R-Crio

What R-Crio does

R-Crio Criogenia S/A is a Brazilian biotechnology company founded in 2014 and headquartered at Rua Cumarú 204, Alphaville Empresarial, Campinas, São Paulo. The company operates a specialized laboratory (CNPJ 19.208.189/0001-30) focused on the collection, processing, multiplication, quality testing, and long-term cryopreservation of mesenchymal stem cells at -196°C in liquid nitrogen. Cell sources include deciduous teeth, wisdom teeth, adipose tissue, and palate tissue. Its customer base spans families with children seeking biological insurance for future regenerative use, adults pursuing preventive medicine, athletes recovering from orthopedic injuries, and individuals with hereditary disease risk profiles. The company holds nine international patents, has published 50 scientific articles, and authored eight books on regenerative medicine and odontology; founder José Ricardo Muniz Ferreira leads the firm, which is privately held with no disclosed outside investors.

The business model blends three revenue streams: subscription-based stem cell storage contracts delivered through R-Crio Plans (which include personalized cell multiplication, credentialed collector consultations, transport logistics, and issuance of a Cryopreservation Certificate), one-time course fees from R-Crio Educacional (an online platform offering two- to 16-hour certified courses in regenerative medicine, gene therapy, biomaterials, and project management priced from free to R$1,599 with installment options), and franchise royalties from three domestic franchise units in Londrina/PR, Mogi das Cruzes/SP, and São Caetano do Sul/SP. Distribution runs exclusively through a Brazilian network of credentialed dentists and doctors, with samples shipped to the Campinas laboratory for processing. The company holds ANVISA Cell Processing Center licensing aligned with RDC 505/2021, RDC 506/2021, and RDC 836/2023, positioning it for the regulated advanced therapy market.

Beyond core storage services, R-Crio is advancing R-Angio-Crio, an Advanced Therapy Product (PTA) using mesenchymal stem cells for neuroprotection, angiogenesis, and inflammatory modulation, which was in pre-clinical development as of 2025 with a stated path toward clinical evaluation. Operations remain entirely domestic (Southeast Brazil) with no international footprint, 11-50 employees, and founder-controlled ownership. Marketing leans on organic social (Instagram, LinkedIn, YouTube), content marketing through the company blog, an educational platform, WhatsApp for bottom-of-funnel conversions, email newsletters, and a customer referral program offering a 5% discount on annual fees.

Name

R-Crio

Legal name

R-Crio Criogenia S/A

Website

https://r-crio.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

11–50 employees

Short description

R-Crio Criogenia S/A is a Brazilian biotechnology company, founded in 2014 in Campinas, that cryopreserves mesenchymal stem cells from deciduous teeth, wisdom teeth, adipose tissue, and palate at -196°C. It serves families and adults seeking preventive regenerative medicine and healthcare professionals seeking credentialed collection partnerships and certified education via R-Crio Educacional.

Ownership category

akta.pro rank

Headquarters

HQ city

Campinas

HQ country

Brazil

HQ region

Latin America

Offices4 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Stem Cell Cryopreservation Services: Collection, processing, multiplication, quality testing, and long-term cryopreservation of mesenchymal stem cells from deciduous teeth, wisdom teeth, adipose tissue, and palate for personal health planning.
2. Educational Courses (R-Crio Educacional): Online courses for healthcare professionals on regenerative medicine, stem cell therapies, gene therapy, biomaterials, and project management. Courses range from 2 to 16 hours with certification.
3. Franchise Units: Licensed franchise operations in Brazil where franchisees operate their own R-Crio branded collection points with their own collection kits and local patient prospecting.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels8 records

Core offering

R-Crio operates a biotechnology laboratory in Campinas, Brazil that collects, processes, multiplies, and cryopreserves mesenchymal stem cells from deciduous teeth, wisdom teeth, adipose tissue, and palate at -196°C in liquid nitrogen for long-term personal storage. Customers contract R-Crio Plans that bundle personalized cell multiplication, credentialed collector consultations, sample transport, quality testing, and a Cryopreservation Certificate. The company also runs R-Crio Educacional, an online platform selling certified courses in regenerative medicine, gene therapy, and biomaterials to healthcare professionals.

Product overview

R-Crio is a Brazilian biotechnology company specializing in stem cell storage and cryopreservation services. The core offering consists of collection, processing, multiplication, and cryopreservation of mesenchymal stem cells from deciduous teeth, wisdom teeth, adipose tissue, and palate at -196°C in liquid nitrogen. Services are delivered through R-Crio Plans, which include personalized stem cell multiplication, credentialed professional consultations, transport logistics, and certification. The company operates R-Angio-Crio, an Advanced Therapy Product (PTA) in pre-clinical development for neuroprotection and angiogenesis. R-Crio also operates R-Crio Educacional, an educational platform offering professional courses in regenerative medicine, gene therapy, biomaterials, and related topics, with franchise opportunities available for health professionals.

Differentiator

Problem solved

Functional benefit

Products and services

• Stem Cell Storage and Cryopreservation Services (R-Crio Plans) End-to-end stem cell cryopreservation service sold to individual consumers and families: collection consultation with a credentialed dentist or doctor, sample transport to the Campinas laboratory, processing and personalized multiplication of mesenchymal stem cells, post-multiplication therapeutic quality testing, and long-term storage in liquid nitrogen at -196°C. Customers receive a Cryopreservation Certificate, Client Portal access, and ongoing newsletter updates; contract structure includes recurring annual storage fees.
• R-Crio Educacional Online continuing-education platform for healthcare professionals (doctors, dentists, biomedics, biochemists, nurses, biologists, biotechnologists) offering 2- to 16-hour certified courses in regenerative medicine, stem cell therapies, gene therapy, biomaterials in regenerative medicine, and project management fundamentals. Courses range from free modules to paid programs up to R$1,599 with 12-installment payment options and certification recognized in the global health sector.

Quantifiable outcome

• Cryopreservation maintains stem cells at the patient's biological age, allowing future cell formation from younger cells while the body ages normally

Named customers2 records

Segments5 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

One partnership is on record.

• Universidade Corporativa da AnademminorStrategic or Co-development PartnerAnadem's corporate university partners with R-Crio for educational content in regenerative medicine, with R-Crio Educacional providing specialized courses for Anadem members.

Scale indicators4 records

Recent moves5 records

Expansion highlights5 records

Direct peers

• Cryo-Cell International: US-based stem cell banking company offering cord blood and tissue cryopreservation services. Directly comparable to R-Crio as a consumer-facing stem cell storage business with recurring storage revenue.
• Future Health Biobank: UK-based family stem cell bank offering cord blood, cord tissue and dental pulp stem cell storage. Comparable to R-Crio as a multi-source consumer stem cell storage service with international reach.
• CordVida: Brazil's largest private umbilical cord blood stem cell bank. Direct Brazilian peer to R-Crio, operating in the same domestic consumer stem cell banking market with similar clinician-driven distribution.
• Bioeden: UK-based stem cell bank specializing in cryopreservation of stem cells from children's teeth. Closely mirrors R-Crio's core proposition of storing mesenchymal stem cells from deciduous teeth for future therapeutic use.
• Cells4Life: UK-based stem cell bank focused on cord blood and tissue storage. Comparable to R-Crio as a private, subscription-based stem cell storage business targeting expectant and family consumers.
• Smart Cells International: UK stem cell bank offering cord blood and tissue storage services globally. Comparable to R-Crio as a family-focused cryopreservation service with recurring storage revenue.
• Precious Cells: UK-based stem cell storage provider offering a range of family banking services. Comparable to R-Crio as a multi-source, recurring-revenue stem cell bank serving families.

Broad incumbents

• Mesoblast: Listed regenerative medicine company commercializing mesenchymal stem cell therapies across multiple indications. Comparable to R-Crio as a mesenchymal stem cell platform with both ATMP development and broader regenerative medicine ambitions.
• ViaCord: Long-established US family cord blood bank now part of a larger life sciences group. Comparable to R-Crio as a branded, consumer-facing family stem cell bank with recurring storage contracts.

Emerging players

• BrainStorm Cell Therapeutics: Clinical-stage cell therapy company developing autologous mesenchymal stem cell therapies for neurodegenerative diseases. Comparable to R-Crio's R-Angio-Crio program as a mesenchymal stem cell-based therapeutic targeting neurological indications.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xinstagram.com/rcriocelulastronco
• YouTubeyoutube.com/@rcriocelulastronco
• LinkedInlinkedin.com/company/r-crio
• Instagraminstagram.com/rcriocelulastronco
• Facebookfacebook.com/rcriocelulastronco

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about R-Crio