Lo.Li. Pharma International

What Lo.Li. Pharma International does

Lo.Li. Pharma International S.r.l. is an Italy-based pharmaceutical company headquartered in Rome, with additional operations in Ancona. It is the global subsidiary of Lo.Li. Pharma Group and was founded by Professor Vittorio Unfer, a gynecologist and pioneering inositol researcher. The company researches, develops, and distributes medical devices and dietary supplements, with a core technology platform centered on Myo-inositol and D-chiro-inositol formulations developed for endocrine, gynecological, and andrological applications.

The company's product portfolio spans four therapeutic areas: gynecology (PCOS management, fertility support, menopause care, vaginal health, and HPV management), endocrinology (thyroid disorders, insulin resistance, metabolic balance, and bone health), andrology (male fertility and hormonal balance), and a newly established therapeutics division covering respiratory, cardiology, and neuropsychiatry. Anchor product lines include the INOFOLIC family (Myo-inositol and alpha-lactalbumin formulations), TIROXIL (thyroid support), DELPHYS and SYNOSTEA (bone health), BIGUANELLE and PERVISTOP (intimate care), ANDROSITOL PLUS and EMOGUT (men's health), and ALERACT (PEA-based nutritional support). The newer Pneumoxytol, Cardiositol, and Deplesin products extend the portfolio into adjacent specialties.

Lo.Li. Pharma operates exclusively through a B2B out-licensing model, partnering with local distributors in 76 countries and providing end-to-end partner support including product registration, strategic positioning, medical education, and marketing tools. Revenue derives from licensing and royalty arrangements with these national partners. The company is privately held under Italian law as a sole-shareholder entity (S.r.l. – Soc. Unipersonale) and holds ISO 9001:2015 certification. Revenue, funding, and detailed financial performance are not publicly disclosed.

Name

Lo.Li. Pharma International

Legal name

Lo.Li. Pharma International S.r.l. – Soc. Unipersonale

Website

https://lolipharmainternational.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

Lo.Li. Pharma International is a Rome-based pharmaceutical company that develops and out-licenses inositol-based medical devices and dietary supplements for gynecology, endocrinology, andrology, and respiratory/cardiology/neuropsychiatry indications to local distribution partners across 76 countries.

Ownership category

akta.pro rank

Product category

Specialty Pharmaceuticals (Women's Health & Endocrinology)

NAICS

Pharmaceutical Preparation Manufacturing (325412), Medicinal and Botanical Manufacturing (325411)

SIC

Pharmaceutical Preparations (2834), Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Women’s Health & Reproductive Specialty Pharmaceuticals (HLAIACAN)

akta.pro secondary industries

Endocrinology & Reproductive Health Pharmaceuticals (incl. Women’s Health) (HLAIAAAJ), Women’s Health Supplements (Prenatal, Menopause, Hormonal) (CRADAGAK), Specialty Pharmacy & Biologics Distribution (CRAOAHAD)

Keywords

• Pharmaceutical out-licensing
• Dietary supplements
• Medical devices
• Inositol formulations
• Gynecological supplements

Headquarters

HQ city

Rome

HQ country

Italy

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Personnel, Operations, Marketing or Sales

Revenue model

1. B2B Out-licensing: The company licenses scientifically proven pharmaceutical solutions (medical devices and food supplements) to local partners in different countries. Partners handle distribution in their national markets while Lo.Li. Pharma provides registration, positioning, and marketing support.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels2 records

Core offering

Lo.Li. Pharma International researches, develops, and out-licenses scientifically validated medical devices and dietary (food) supplements built principally around proprietary inositol (Myo-inositol and D-chiro-inositol) formulations. The portfolio addresses gynecology (PCOS, fertility, menopause, vaginal health, HPV), endocrinology (thyroid, metabolic, bone health), and andrology (male fertility), with a newer division covering respiratory, cardiology, and neuropsychiatry conditions. Products are produced in Italy and distributed globally through a B2B partner network in 76 countries rather than sold directly to end consumers.

Product overview

Lo.Li. Pharma International is a global pharmaceutical company specializing in medical devices and food supplements. The product portfolio spans four main therapeutic areas: Gynecology (including PCOS, fertility, menopause, vaginal health, and HPV), Endocrinology (thyroid disorders, dysmetabolism, osteopenia/osteoporosis), Andrology (male fertility and reproductive health), and a newly established division covering Respiratory, Cardiology, and Neuropsychiatry. The INOFOLIC® product family (HP, COMBI HP, PLUS, PLUS CAPS, LUTEAL, PHD®) forms a core pillar centered on Myo-inositol and Alpha-lactalbumin formulations for hormonal and metabolic support. The company also offers thyroid-support products (TIROXIL® line), bone health supplements (SYNOSTEA®, DELPHYS® line), intimate care solutions (PERVISTOP® line, BIGUANELLE® devices), men\'s health products (ANDROSITOL® PLUS, EMOGUT® line), and the newer Lo.Li. Pharma Therapeutics division covering respiratory (PNEUMOXYTOL®), cardiovascular (CARDIOSITOL®), and neuropsychiatric (DEPLESIN®) conditions. All products are distributed through a B2B out-licensing model across 76 countries.

Differentiator

Problem solved

Functional benefit

Brands

• Lo.Li. Pharma Therapeutics: A newly established division of Lo.Li. Pharma International focusing on respiratory, cardiology, and neuropsychiatry therapeutic areas including products like Pneumoxytol, Cardiositol, and Deplesin.

Products and services

• ALERACT HA Dietary supplement containing hyaluronic acid, magnesium, vitamin B6, and vitamin D for additional nutrient supply in cases of reduced dietary intake or increased nutritional requirements.
• ANDROSITOL PLUS Dietary supplement containing myo-inositol, N-acetyl-L-cysteine, vitamin E, L-carnitine, L-arginine, alfa-lactalbumin, folic acid, and selenium. Selenium contributes to normal spermatogenesis.
• BIGUANELLE Solution Vaginal solution for feminine intimate care.
• BIGUANELLE Vaginal Suppository Vaginal suppository for feminine intimate care.
• BIGUANELLE Gel Intimate hygiene gel product for feminine care.
• DELPHYS Plus Dietary supplement with Vitamin D, Epigallocatechin Gallate, D-chiro-inositol, and Vitamin B6; supports additional nutrient supply and helps maintain testosterone and estradiol homeostasis.
• DELPHYS Dietary supplement with Vitamin D, Epigallocatechin Gallate, and Vitamin B6 supporting cell division and regulation of hormonal activity.
• ELYANNA Food supplement based on Myo-inositol, Diosgenin, Vitamin D, and Alpha-lactalbumin; Dioscorea villosa helps counter menstrual cycle disorders.
• EUMASTÒS Dietary supplement containing folic acid, betaine, vitamins B2, B6, B12, myo-inositol, N-acetylcysteine, and Boswellia serrata extract; Boswellia serrata helps counter localized states of tension.
• EUMASTÒS Gel Topical gel medical device for localized tension relief.
• EUDIAMET 40:1 Dietary supplement containing Myo-inositol, Gymnema Sylvestre, D-chiro-inositol, alpha-lactalbumin, and zinc for additional nutrient supply.
• EMOGUT FORTE Dietary supplement containing alpha-lactalbumin and microencapsulated iron pyrophosphate (SunActive Fe); supports normal red blood cell and hemoglobin formation and reduces tiredness and fatigue.
• EMOGUT Dietary supplement containing alpha-lactalbumin and folic acid supporting normal hematopoiesis, reduction of tiredness and fatigue, and normal homocysteine metabolism.
• SANTES Dietary supplement product for feminine health.
• SANTES Gel Topical gel medical device product for feminine health.
• IALOS Dietary supplement containing hyaluronic acid for additional nutrient supply in cases of reduced dietary intake or increased bodily requirement.
• INOFOLIC HP Dietary supplement containing Myo-inositol, alpha-lactalbumin, and folic acid for additional nutrient supply, foundational to PCOS management.
• INOFOLIC PHD Dietary supplement with Diosgenin, Alpha-lactalbumin, and Vitamin D; Dioscorea villosa helps alleviate menstrual cycle disorders.
• INOFOLIC COMBI HP Dietary supplement containing Myo-inositol, alpha-lactalbumin, D-chiro-inositol, and folic acid for additional nutrient supply.
• INOFOLIC LUTEAL Dietary supplement with Myo-inositol, melatonin, folic acid, and vitamin D; melatonin contributes to reduced sleep onset time.
• INOFOLIC PLUS Dietary supplement containing myo-inositol, melatonin, and folic acid; melatonin helps reduce time to fall asleep.
• INOFOLIC PLUS CAPS Capsule-format dietary supplement containing myo-inositol, melatonin, and folic acid; melatonin helps reduce time to fall asleep.
• PERVISTOP Dietary supplement containing epigallocatechin gallate (EGCG), hyaluronic acid, vitamin B12, and folic acid for additional nutrient supply related to vaginal and intimate wellness.
• PERVISTOP Foam pH 4.5 intimate cleanser with polyhexamethylene biguanide (PHMB) for daily intimate hygiene, contributing to an environment unfavorable to microbial growth with hydrating, emollient, rebalancing, protective and soothing action.
• PROT-AGE Dietary supplement with myo-inositol, cocoa polyphenols, and soy isoflavones for women during menopause; soy extract helps counteract climacteric disorders and supports balanced lipid metabolism.
• SYNOSTEA Dietary supplement with D-chiro-inositol, Alpha-lactalbumin, Calcium, Vitamin D, and Vitamin K contributing to maintenance of normal bones.
• TECADRIOL 600 Dietary supplement containing D-chiro-inositol and alpha-lactalbumin for additional nutrient supply.
• TIROXIL D Dietary supplement with Myo-inositol, Selenium, and Vitamin D; selenium supports normal thyroid function and vitamin D supports normal calcium absorption and bone health.
• TIROXIL 0.4 Dietary supplement containing L-Carnitine and Selenium supporting normal thyroid function.
• TIROXIL 4.0 Dietary supplement with Myo-inositol and Selenium supporting normal thyroid function.
• ZYXELLE Dietary supplement with vitamins, minerals, and Centella Asiatica; helps get rid of cellulite and reduces swelling (heavy legs).
• ZYXELLE PLUS Dietary supplement with vitamins, minerals, and Centella Asiatica; supports macronutrient metabolism via biotin and bone health via vitamin D.
• IODACT Dietary supplement containing Myo-inositol and Iodine supporting normal thyroid hormone production and thyroid function.
• XYMINAL Dietary supplement product for male health.
• Pneumoxytol Sachets Dietary supplement based on Myo-Inositol, N-Acetyl-L-Cysteine, and Alpha-Lactalbumin for additional nutrient intake in respiratory conditions.
• Pneumoxytol Kids Pediatric respiratory dietary supplement marketed under the Lo.Li. Pharma Therapeutics division.
• Pneumoxytol Medical Device Medical device for respiratory conditions marketed under the Lo.Li. Pharma Therapeutics division.
• Deplesin 80:1 Dietary supplement marketed under the Lo.Li. Pharma Therapeutics division for neuropsychiatric indications.
• Cardiositol Cardiometabolic dietary supplement marketed under the Lo.Li. Pharma Therapeutics division for cardiac health and cardiometabolic conditions.

Quantifiable outcome

• Present in 76 countries worldwide

Segments4 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature1 record

Partnerships

One partnership is on record.

• Local Distribution PartnerscoreChannel Partner/ Reseller/ DistributorLo.Li. Pharma International collaborates with a trusted network of local partners who bring their products to national markets. These partners handle distribution within their respective countries and adapt products to local clinical, regulatory, and cultural needs. The company provides end-to-end support including product registration, strategic positioning, medical education, and marketing tools.

Scale indicators2 records

Recent moves5 records

Expansion highlights4 records

Direct peers

• Ovasitol: US-based inositol supplement brand (myo-inositol + D-chiro-inositol in 40:1 ratio) marketed specifically for PCOS and fertility — the closest direct competitor to Lo.Li. Pharma's flagship INOFOLIC Combi HP.
• Italfarmaco: Italian-headquartered specialty pharmaceutical company with a strong women's health and gynecology portfolio (and owner of Effik). Comparable in geographic origin, therapeutic focus on reproductive health, and out-licensing presence in international markets.
• Theramex: Specialty women's health pharmaceutical company operating across contraception, fertility, menopause, and gynecological conditions. Highly comparable to Lo.Li. Pharma's core women's health/gynecology franchise with similar B2B distribution model across international markets.
• Exeltis: Global specialty pharma focused on women's health (contraception, fertility, menopause, gynecological health). Comparable in therapeutic alignment with Lo.Li. Pharma's INOFOLIC/gynecology portfolio and in B2B out-licensing go-to-market across multiple regions.

Broad incumbents

• Recordati: Italian-listed specialty pharmaceutical company with established women's health, endocrinology, and rare disease franchises. Comparable in Italian origin, endocrinology focus, and global B2B/partner distribution model, though at significantly larger scale.
• Zambon: Italian multinational pharmaceutical company with women's health, respiratory, and CNS therapeutic areas. Comparable in Italian heritage, therapeutic breadth (now overlapping with Lo.Li. Pharma Therapeutics' respiratory/neuropsychiatry push), and international B2B presence.
• Bayer Women's Health: Global pharmaceutical incumbent with a dedicated women's health franchise (contraception, menopause, gynecological therapies). Overlaps with Lo.Li. Pharma's therapeutic categories but at much larger scale and broader portfolio scope.
• Angelini Pharma: Private Italian pharmaceutical group with international operations in women's health, CNS, and consumer health. Comparable as a privately-held Italian pharma peer operating globally with specialty therapeutic divisions.
• Gedeon Richter: Hungarian-headquartered multinational with a major women's health franchise (contraception, fertility, menopause). Comparable therapeutic categories and global commercial reach, though much larger and broader in scope.

Emerging players

• Theralogix: US reproductive-health supplement company focused on fertility, PCOS, and prenatal nutrition, with Ovasitol as its lead brand. Comparable in mechanism (inositol-based) and PCOS therapeutic positioning, though operating primarily direct-to-consumer rather than via B2B licensing.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/lo_lipharmainternational
• Facebookfacebook.com/profile.php

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Lo.Li. Pharma International