CMA Microdialysis - Preclinical Business

What CMA Microdialysis - Preclinical Business does

CMA Microdialysis AB is a Sweden-based, privately held manufacturer of microdialysis research solutions, headquartered in Kista near the Karolinska Institute with a US commercial office operated through Harvard Apparatus in Holliston, Massachusetts. The company develops and sells a complete portfolio of preclinical research tools — concentric microdialysis probes with semi-permeable membranes, precision peristaltic pumps (REGLO ICC), stereotaxic implantation instruments (compact, U-frame, and digital variants), microfraction collectors, and accessories including FEP tubing, perfusion fluids, syringes, and surgical tools. Probe lines span CNS applications (CMA 7, 8, 11, 12) for rat and mouse brain studies, peripheral tissue applications (CMA 20, 22 Flex, 30, 31) for soft moving tissues, and large-molecule probes with MWCO ranging from 6 kDa up to 2 MDa; complementary tissue-processing instruments include Compresstome vibrating microtomes and cryostats.

The business operates a hardware-sales revenue model with unit-priced consumables (probes typically sold in packages of three at low-to-mid three-figure price points) and higher-priced capital instruments, supplemented by a custom-probes-and-guides manufacturing service for specialized research applications. Pricing is in USD for US customers and in local currency quotes internationally, with login-gated US pricing and a configuration-assistance workflow that indicates an enterprise sales motion with technical consultation. Distribution runs through direct sales from Sweden HQ and the US Harvard Apparatus office, with a global distributor network covering countries outside the direct-sales footprint.

CMA Microdialysis serves preclinical research institutions, pharmaceutical and biotechnology drug-development groups, and a smaller base of environmental and agricultural researchers, addressing use cases in neurotransmitter analysis, pharmacokinetics, drug distribution, blood-brain barrier penetration, and tissue chemistry exploration. The company is positioned by its own materials as the market leader for full microdialysis research solutions.

Name

CMA Microdialysis - Preclinical Business

Legal name

CMA Microdialysis AB

Website

https://microdialysis.com

Company type

Private

Operating status

Operating

Short description

CMA Microdialysis AB is a Swedish specialty manufacturer of preclinical microdialysis probes, peristaltic pumps, stereotaxic instruments, and accessories, supplying academic neuroscience labs and pharmaceutical/biotech drug-development groups globally through direct sales, Harvard Apparatus in the US, and a distributor network.

Ownership category

akta.pro rank

Product category

Preclinical Microdialysis Research Equipment

NAICS

Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451)

SIC

Laboratory Analytical Instruments (3826), Laboratory Apparatus & Furniture (3821)

akta.pro primary industry

Liquid Handling & Laboratory Automation (Pipettes, Robots, Workstations) (HLAGAIAD)

Keywords

• Microdialysis probes
• Preclinical research equipment
• Stereotaxic instruments
• Tissue chemistry analysis
• Pharmacokinetic research tools

Headquarters

HQ city

Solna

HQ country

Sweden

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Technology or R&D, Operations, Marketing or Sales

Revenue model

1. Microdialysis Probes and Accessories: Sale of specialized microdialysis probes including CNS probes for rat and mouse, peripheral tissue probes, large molecule probes, and consumables such as perfusion fluids, syringes, and tubing.
2. Scientific Instruments: Sale of instruments including microfraction collectors, stereotaxic instruments, digital instruments, manipulator arms, and tissue slicers (Compresstome vibrating microtomes).
3. Custom Probes and Guides: Custom microdialysis probes and guide cannulae manufactured to customer specifications for specialized research applications.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels6 records

Core offering

CMA Microdialysis manufactures and sells specialized microdialysis probes (CNS probes for rat/mouse brain studies, peripheral tissue probes, large-molecule probes with MWCO from 6 kDa to 2 MDa), precision peristaltic pumps (REGLO ICC), microfraction collectors, complete stereotaxic instrument systems, and related consumables/accessories used by preclinical researchers to sample extracellular fluids and measure chemical compounds in living tissue.

Product overview

CMA Microdialysis is a market leader in microdialysis research solutions, offering a comprehensive portfolio of probes, instruments, and accessories. The core product line centers on CMA microdialysis probes including CNS probes (CMA 7, 8, 11, 12) for stereotaxic brain studies in rats and mice, peripheral tissue probes (CMA 20, 22 Flex, 30, 31) for soft moving tissues, and large molecules probes with molecular weight cut-offs from 6 kDa up to 2 MDa. Supporting instrumentation includes the REGLO ICC Digital Peristaltic Pump for precision fluid control, complete stereotaxic instrument systems (Compact, U-Frame, Digital variants) for precise probe implantation, and specialized accessories including FEP tubing, perfusion fluids, and surgical tools. The portfolio also extends to tissue processing equipment including Compresstome vibrating microtomes and cryostats. All products are manufactured to the highest quality standards specifically for microdialysis applications with research-use-only designation.

Differentiator

Problem solved

Functional benefit

Products and services

• CMA 7 Microdialysis Probes Microdialysis probes designed for specific research applications in preclinical studies.
• CMA 8 Microdialysis Probes for Transgenic Mice (20 kDa and 100 kDa MWCO) Specialized probes for transgenic mouse studies with molecular weight cut-offs of 20 kDa and 100 kDa for targeting specific molecules.
• CMA 11 Microdialysis Probes for Discrete Areas of CNS CNS probes designed for stereotaxic work in discrete areas of the brain in rats, ideal for both anesthetized and conscious animals.
• CMA 12 Microdialysis Probes for Stereotaxic Studies (20 kDa and 100 kDa MWCO) Stereotaxic CNS probes with PAES 20 kDa MWCO or PES 100 kDa MWCO membranes, available in metal-free versions with 1, 2, 3, or 4 mm membrane lengths.
• CMA 20 Microdialysis Probes for Soft Moving Tissues (20 kDa and 100 kDa MWCO) Designed for dialysis experiments in moving soft tissues including muscle, heart, skin, adipose tissue, blood, and vitreous fluid of the eye. Soft, non-metallic plastic construction with 4, 10, and 30 mm membrane lengths.
• CMA 22 Flex Microdialysis Probes Flexible probes for peripheral tissue and organs in freely moving mice. New guide design enables long-term studies and intermittent microdialysis. Membranes from 6 kDa up to 2 MDa MWCO; 30mm and 38mm shaft lengths; 3mm and 4mm membrane lengths.
• CMA 30 Linear Microdialysis Probe for Peripheral Tissues (6 kDa MWCO) Linear microdialysis probe for peripheral tissue sampling with 6 kDa molecular weight cut-off.
• CMA 31 Linear Microdialysis Probe for Peripheral Tissues (55 kDa MWCO) Linear microdialysis probe for peripheral tissue sampling with 55 kDa molecular weight cut-off.
• CMA Guide Cannulae Guide cannulae for use with CMA microdialysis probes to facilitate precise implantation in research subjects.
• CMA Custom Probes & Guides Custom-designed microdialysis probes and guide cannulae manufactured to customer specifications for specialized research applications.
• REGLO ICC Digital Peristaltic Pump Independent Channel Control digital peristaltic pump with individually programmable channels (2, 3, or 4 channel variants), 12 rollers for smooth flow down to 0.1 µl/min, bidirectional flow, and USB interface. Recommended for large molecule microdialysis with push-pull system.
• Stereotaxic Instruments Complete line of stereotaxic instruments including Compact, Elevated U-Frame, Large Animal, and Digital variants for precise probe implantation in preclinical research.
• Digital-Compact Stereotaxic Instruments for Mouse Only Digital stereotaxic instrument with LCD display showing real-time coordinates for all three axes at 10 µm resolution. Available in single, dual, or two-mouse configurations with battery or AC power options.
• Compact Stereotaxic Instruments for Mouse and Rat Compact stereotaxic instruments with small footprint, available with manual or digital manipulator arms with 10 µm resolution. Dual-lead screw design for stable, accurate manipulations.
• Compresstome Vibrating Microtomes (Tissue Slicers) Vibrating microtomes for tissue sectioning in research applications.
• Cryostats Cryostats for histological sectioning in research applications.
• Microdialysis Syringes Syringes and syringe accessories for microdialysis perfusion and sample collection.
• CMA Microdialysis Perfusion Fluid Perfusion fluid for microdialysis experiments, designed for optimal probe performance.
• Micro Bone Drill High-speed drill (up to 38,000 rpm) for breaking through skull during stereotaxic procedures, with forward/reverse rotation and footswitch control. Drill bits sold separately.

Quantifiable outcome

• Probes validated in published peer-reviewed research including pharmacokinetic studies, neurotransmitter analysis, and drug distribution research

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Two partnerships are on record, tiered core and minor.

• Harvard ApparatuscoreChannel Partner/ Reseller/ DistributorHarvard Apparatus serves as the US sales and distribution arm for CMA Microdialysis products, operating from 84 October Hill Road, Holliston, Massachusetts. The company handles US phone orders and customer support for North American customers.
• Global Distributor NetworkminorChannel Partner/ Reseller/ DistributorCMA Microdialysis maintains a network of distributors worldwide to serve customers in countries outside their direct sales coverage areas in Sweden and the United States.

Scale indicators1 record

Recent moves6 records

Expansion highlights5 records

Emerging players

• Narishige International: Japanese manufacturer of micromanipulators, microinjectors, and stereotaxic instruments for neuroscience and cell biology research. Adjacent product overlap with CMA's stereotaxic instrument line, primarily serving Japanese and Asian research markets.

Broad incumbents

• Hamilton Company: Large manufacturer of precision laboratory equipment including syringes, pumps, and liquid handling systems. Overlaps with CMA's REGLO ICC pump and related fluid handling components in lab research settings, with broader portfolio reach.
• Harvard Bioscience: Parent/related entity through Harvard Apparatus brand with broader life science research equipment portfolio including cellular analysis, electrophysiology, and surgical instruments. Also a key distribution channel partner for CMA Microdialysis products in North America.
• Thermo Fisher Scientific: Massive life science tools conglomerate with broad lab equipment portfolio. While not a direct microdialysis competitor, overlaps with adjacent lab consumables and instruments (cryostats, microscopes, lab automation) serving similar pharma and academic customers at a much broader scale.

Direct peers

• World Precision Instruments (WPI): US manufacturer of laboratory instruments and consumables for life science research including microdialysis probes, micromanipulators, and stereotaxic equipment, serving overlapping neuroscience and pharmacology research customers with parallel product categories.
• Amuza (formerly Eicom): Japanese manufacturer of microdialysis HPLC systems and automated sampling platforms. Directly competes with CMA in the microdialysis analysis workflow for neuroscience and pharmacology research, particularly in Asian markets.
• Stoelting Co. Manufacturer of stereotaxic instruments and neuroscience research equipment. Directly competes with CMA's stereotaxic instrument line (Compact, U-Frame, Digital variants) for probe implantation in rodent research applications across academic and pharma labs.
• M Dialysis AB: Direct Swedish competitor in microdialysis products, also headquartered in Sweden. Offers competing microdialysis probes and equipment for preclinical research, serving neuroscience and pharmacology research customers nearly identical to CMA's core segments.
• Kopf Instruments: Established US manufacturer of stereotaxic instruments and related neuroscience research tools. Competes directly with CMA's stereotaxic product line in academic and pharma neuroscience research labs, particularly for rodent stereotaxic surgery applications.
• Bioanalytical Systems, Inc. (BASi): US-based life science tools company with established microdialysis product line (Culex automated sampling systems). Serves similar pharma/biotech and academic customers for in vivo sampling and preclinical research, with overlapping sales channels and customer use cases.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xtwitter.com/CMicrodialysis
• LinkedInlinkedin.com/company/cma-microdialysis

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

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