Histion, LLC

What Histion, LLC does

Histion, LLC operates within Inotiv, Inc. (NASDAQ: NOTV), a publicly traded Discovery and Development Contract Research Organization headquartered in West Lafayette, Indiana, with operations spanning Everett and broader U.S. and global markets. The company delivers nonclinical testing services, research models, and laboratory analysis solutions across the drug development continuum from discovery through IND-enabling and pre-marketing authorization. Its service portfolio is organized into three primary lines: Discovery and Translational Sciences (disease pharmacology, DMPK, bioanalysis, cell and molecular biology, computational toxicology, toxicogenomics, targeted proteomics, histology and pathology); Safety Assessment (general and genetic toxicology, safety pharmacology, DART, carcinogenicity, GLP bioanalysis, medical device testing, SEND, cell and gene therapy); and Research Models and Services (genetically engineered models, contract breeding, surgical services, custom antibody production, biospecimen, genetic testing), supplemented by the Teklad sub-brand of laboratory animal diets, bedding, and welfareplus+ enrichment products.

The underlying technology stack combines GLP and non-GLP compliant laboratory infrastructure with proprietary customer-facing platforms, including the LabTracks web portal for project data and task management and the Eusoft Labs LIMS for health monitoring and sample tracking. Digital pathology is delivered via whole slide imaging paired with AI-driven quantitative image analysis, while ADC target quantification is performed via mass spectrometry assays covering 27 oncology and other targets. Revenue is generated through three mechanics: professional services contracts for CRO studies, one-time/model-based sales of research models and related services, and product sales of Teklad diets, bedding, and enrichment. Pricing is primarily quote-based for CRO services, with specialized tiers for NCI grantees and promotional pricing for new academic customers. Distribution runs through direct enterprise sales globally, online ordering for Teklad products, self-service customer portals, and a specialized NCI Grantee program. Customer segments are pharmaceutical and biotechnology companies (primary), plus government agencies, academic institutions, and life science organizations.

Name

Histion, LLC

Legal name

Inotiv, Inc.

Website

https://inotiv.com

Company type

Public

Founded year

2006

Operating status

Operating

Headcount range

11–50 employees

Short description

Histion, LLC operates within Inotiv, Inc., a publicly traded nonclinical CRO providing drug discovery, safety assessment, research models, and Teklad laboratory diets to pharmaceutical, biotechnology, government, and academic customers worldwide.

Ownership category

akta.pro rank

Product category

Preclinical Contract Research Services

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)

akta.pro primary industry

Pathology & Histopathology Services (HLAGAFAI)

akta.pro secondary industries

Anatomic Pathology & Histopathology (Trial Support) (HLAGAEAC), Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI), Anatomic Pathology & Histology/Cytology IVD (Tissue Diagnostics) (HLAHAAAE), Real-World Evidence (RWE), HEOR & Epidemiology CROs (HLAGAAAK)

Keywords

• Medical device testing
• Preclinical research services
• Histology services
• Biomedical product development
• Surgical support services

Headquarters

HQ city

Everett

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Contract Research Services: Inotiv generates revenue through nonclinical contract research services spanning discovery, IND-enabling, and preclinical development phases. Services include toxicology, bioanalysis, pathology, DMPK, and safety assessment studies conducted under GLP and non-GLP conditions.
2. Research Models and Related Services: Sale of research models (rodents and other species) along with supporting services including genetically engineered models, contract breeding, surgical services, genetic testing, and biospecimen services.
3. Laboratory Animal Diets and Supplies: Sale of Teklad laboratory animal diets (standard, custom, medicated), bedding, and environmental enrichment products for research animal colonies.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels4 records

Core offering

Histion, LLC provides scientific and technical expertise and develops products for the Medical Device, Pharmaceutical, and Biotechnology Industries. Operating within Inotiv as a Discovery and Development Contract Research Organization (CRO), Histion delivers nonclinical testing, medical device testing, histology and pathology services, surgical support, and research model-related services across the drug and device development continuum.

Differentiator

Problem solved

Functional benefit

Brands

• Teklad: Laboratory animal diets, bedding, and enrichment products including standard natural ingredient diets, custom research diets, medicated diets, and bedding/enrichment products.

Products and services

• Medical Device Testing and Surgical Support Nonclinical medical device testing services and surgical support for medical device manufacturers and developers across the product lifecycle.
• Histology and Pathology Services Histology and pathology evaluation services supporting drug discovery, toxicology studies, and preclinical development programs for pharmaceutical and biotechnology clients.
• Disease Pharmacology Services In vitro and in vivo disease pharmacology studies covering multiple therapeutic areas for pharmaceutical and biotech drug discovery programs.
• Genetic Toxicology Services (GLP and Non-GLP) Genetic toxicology testing under GLP and non-GLP conditions to support regulatory submissions and safety assessment programs.
• Research Models and Services Comprehensive range of research models including genetically engineered models and services (GEMS), contract breeding, surgical services, custom antibody production, biospecimen services, and genetic testing for research organizations.
• Teklad Laboratory Animal Diets Standard natural ingredient diets, custom research diets, and medicated diets for laboratory animal species with fixed formulation philosophy ensuring consistent batch-to-batch quality.
• Safety Assessment Services Nonclinical safety testing services including general toxicology, safety pharmacology, developmental and reproductive toxicology (DART), carcinogenicity studies, and bioanalysis under GLP conditions.

Quantifiable outcome

• First quarter fiscal 2026 revenue increased 0.8% to $120.9 million

Named customers5 records

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• CumberlandcoreStrategic or Co-development PartnerCumberland is referenced as part of Inotiv's corporate structure, with a dedicated 'About Cumberland' page on the company website, suggesting a parent-subsidiary or affiliated company relationship.

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Emerging players

• HistoWiz: Specialized digital pathology and histology services provider for academic and biotech clients — emerging player directly competing in Histion's core histopathology services niche with a digital-first positioning.
• Flagship Biosciences: Specialty histopathology and tissue image analysis CRO focused on quantitative digital pathology for pharma/biotech drug development — emerging niche player with overlapping offerings to Histion's histology and digital pathology services.

Direct peers

• Charles River Laboratories: Global CRO offering discovery, safety assessment, and research models services — directly comparable to Histion/Inotiv's nonclinical testing and research models portfolio with histology capabilities embedded within its Safety Assessment segment.
• WuXi AppTec: China-headquartered CRO offering discovery, preclinical, and laboratory testing services with comparable capabilities in toxicology, DMPK, and safety assessment for global pharma customers.
• Labcorp: Major CRO via Labcorp Drug Development (formerly Covance) providing nonclinical, central lab, and bioanalytical services across the drug development lifecycle — directly comparable in histopathology and safety assessment work.
• Pharmaron: Global CRO providing drug discovery, preclinical, and CMC services — directly comparable as a CRO offering toxicology, DMPK, safety assessment, and laboratory services across discovery and development phases.
• ICON plc: Global CRO offering laboratory services, bioanalytical, and central lab capabilities — competes with Histion for outsourced preclinical histopathology and safety assessment work.

Broad incumbents

• Medpace: Mid-sized CRO offering full-service clinical development — relevant for outsourced drug development services model although it is more clinical-stage focused than Histion's preclinical histology niche.
• IQVIA: Largest global CRO with end-to-end clinical and preclinical capabilities — relevant comparable for size, customer base, and integrated service model even though it does not specialize narrowly in histopathology like Histion.
• Eurofins Scientific: Global testing services group with significant bioanalytical, central lab, and pharma services exposure — comparable as a contract laboratory services provider serving pharma/biotech sponsors.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xtwitter.com/InotivCRO
• LinkedInlinkedin.com/company/inotiv

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Histion, LLC