What Quad Five does

Quad Five is a Montana-based biotechnology firm specializing in the production of medical-grade animal blood and serum products for use in human diagnostic testing. Founded in 1988 and operating as a division of Materials Bio Inc., the company runs a 100% donor animal operation on a 9,000-acre ranch in Ryegate, Montana, harvesting blood from sheep, horses, bovine, and goats under controlled protocols covering genetics, diet, health, and environment. The facility is USDA-inspected (license MT-TEC-0001) and compliant with European Union Regulation (EC) No. 1774/2002, with over 2 million liters of blood products processed across its 33+ year operating history.

The company's catalog spans 128 SKUs including defibrinated blood, washed red blood cells, blood preserved in seven anticoagulant variants (ACD, Alsevers, Citrate, EDTA, Heparin, Potassium Oxalate, plus custom options), lysed and laked blood variants, sera, plasma, and plasma-derived serum across four core species plus newborn calf and rabbit. Products are collected and processed within 8-48 hours of shipment under cGMPs, with serum filtered through 0.2μm pharmaceutical-grade filters and filled under Class 100 conditions; full traceability is maintained from individual donor animal through final batch file.

Quad Five operates a direct-sales business serving clinical medical centers, laboratories, universities, and pharmaceutical companies globally through online ordering, phone, email, and fax channels. Unit pricing ranges from $31.25 to $547.75 depending on species, product, and volume, with a $35 minimum order charge and volume discounts available. Domestic fulfillment uses FedEx Overnight and UPS Next Day Air, while international orders ship via FedEx International Priority and UPS Worldwide Express, with same-day shipping available for orders received before 10 a.m. Mountain Time. The leadership team is small and tenured (1-10 employees total), with President/Owner Matt McAndrews (16 years), Office Manager Candy Mitchell (24 years), and Livestock Supervisor Ramiro Riviera (23 years) anchoring operations.

Name

Quad Five

Legal name

Materials Bio Inc.

Website

https://quadfive.com

Company type

Private

Founded year

1988

Operating status

Operating

Headcount range

1–10 employees

Short description

Quad Five produces 128 medical-grade animal blood and serum products from donor sheep, horses, bovine, and goats on a 9,000-acre Montana ranch, serving clinical medical centers, laboratories, universities, and pharmaceutical companies globally with 100% traceable, antibiotic-free biological inputs for diagnostic testing.

Ownership category

akta.pro rank

Product category

Biotechnology Reagents

NAICS

Biological Product (except Diagnostic) Manufacturing (325414)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Biological Products, (No Disgnostic Substances) (2836), Agricultural Prod-Livestock & Animal Specialties (200)

akta.pro primary industry

Biologics & Immunotherapies (Non-vaccine) (HLAMAEAK)

Keywords

• Medical-grade animal blood
• Diagnostic serum products
• Biological raw materials
• Donor animal blood collection
• Custom blood processing

Headquarters

HQ city

Ryegate

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Supply Chain, Personnel, Operations, Technology or R&D, Infrastructure

Revenue model

1. Animal Blood and Serum Products: Quad Five generates revenue through the sale of 128 medical-grade animal blood and serum products collected from donor sheep, horses, bovine, and goats. Products are sold as customized, on-demand offerings with various processing options including defibrinated, anticoagulant-preserved, washed, lysed, and laked blood products, as well as serum and plasma variants.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels3 records

Core offering

Quad Five produces medical-grade, customized, on-demand animal blood and serum products (128 SKUs) harvested from donor sheep, horses, bovine, and goats raised on a 9,000-acre Montana ranch. Products include defibrinated blood, washed red blood cells, blood preserved in various anticoagulants (ACD, Alsevers, Citrate, EDTA, Heparin, Potassium Oxalate), lysed and laked blood fractions, sterile-filtered serum, and plasma, processed within 8-48 hours of shipment. These biologicals serve as raw materials for diagnostic kit manufacturers, clinical laboratories, pharmaceutical companies, and universities conducting human diagnostic testing, cell culture, vaccine manufacture, and microbiological culture media applications.

Product overview

Quad Five is a medical-grade animal blood and serum products company offering 128 customized, on-demand blood products for use in human diagnostic testing. The product portfolio centers on four main species (sheep, horse, bovine, and goat) and includes defibrinated blood products (the core offering for pour-plate manufacturers), washed red blood cells in saline or PBS, blood preserved in various anticoagulants (ACD, Alsevers, Citrate, EDTA, Heparin, Potassium Oxalate), lysed blood, laked blood, and laked/lysed supernate blood. Serum products include sterile filtered sera from all four donor species plus newborn calf serum and rabbit serum. Plasma products and plasma-derived serum are also available. All products are collected within 8-48 hours of shipment, processed at their Montana facility, and shipped globally to clinical medical centers, laboratories, universities, and pharmaceutical companies. Custom product configurations (packaging, volume, dispensing ports) and custom anticoagulants are offered upon request.

Differentiator

Problem solved

Functional benefit

Products and services

• Defibrinated Sheep Blood Fibrin-free sheep blood for diagnostic applications. Blood is mechanically defibrinated in the original collection bag and pooled before transfer to final packaging.
• Defibrinated Horse Blood Horse blood with fibrin removed, ideal for microbiological and diagnostic use. Core product for pour-plate manufacturers.
• Defibrinated Bovine Blood Bovine blood without fibrin for diagnostic purposes. Providing bulk bovine blood to pour-plate manufacturers is core to Quad Five's business.
• Defibrinated Goat Blood Goat blood without fibrin, ideal for diagnostic tests.
• Sheep Serum Sterile filtered sheep serum used in culture media, diagnostic kits, tissue culture, and vaccine manufacture.
• Horse Serum Sterile horse serum for cell culture and diagnostic applications.
• Bovine Serum Bovine serum commonly used in cell culture and research.
• Goat Serum Goat serum for biological research and culture media.
• Horse Serum, Heat Inactivated Processed to inactivate complement proteins while preserving essential growth factors. Ideal for applications sensitive to complement activity.
• New Born Calf Serum Sourced from newborn calves, commonly used in cell culture and lab applications.
• Rabbit Plasma/EDTA Rabbit plasma preserved with EDTA for specialized applications.
• Rabbit Serum Serum from rabbit blood used in research and diagnostic testing.
• Washed Red Blood Cells (Sheep, Horse, Bovine, Goat) Red blood cells purified by washing three times with .85% saline and packaged 50:50 v/v in .85% saline. Cells also available using PBS (phosphate buffered saline). Minimum packed cell volume: 35% for sheep/goats, 38% for horses/cattle.
• Blood in Anticoagulants (ACD, Alsevers, Citrate, EDTA, Heparin, Potassium Oxalate) Blood available in various anticoagulants including ACD, Alsevers, Citrate, Sodium Oxalate, Heparin, EDTA, and Potassium Oxalate across sheep, horse, bovine, and goat. Custom anticoagulants also available upon request.
• Laked and Lysed Blood (Sheep, Horse, Bovine, Goat) Defibrinated blood lysed using 50:50 v/v sterile D.I. water (lysed), processed through three freeze/thaw cycles (laked), and shipped frozen for extended shelf life. Laked/lysed supernate variants also available after centrifugation to remove cell debris.
• Plasma (Sheep, Horse, Bovine, Goat) Sheep, horse, bovine, and goat plasma available in anticoagulant and packaging of choice, provided as raw material or sterile filtered. Quad Five maintains inventory of sterile plasma produced in citrate for all four donor species.
• Plasma Derived Serum (Sheep, Horse, Bovine, Goat) Available from all four donor species. Collected in acid citrate dextrose and artificially clotted with CaCl2 to remove fibrin but retain clotting factors.
• Custom Products Customized blood packaging, volume, and dispensing-port configuration of ship bags to best suit customer pouring equipment. Sterile, medical-grade oxygen can be added to blood at customer request for specific media applications or plate appearance.

Quantifiable outcome

• Over 2 million liters of blood products processed
• +2 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Scale indicators4 records

Recent moves5 records

Expansion highlights4 records

Direct peers

• Lampire Biological Laboratories: Lampire is one of the largest US producers of animal blood products, serum, and plasma for diagnostics and research, directly competing with Quad Five in defibrinated blood, washed red cells, and specialty serum offerings across multiple species.
• Innovative Research: Innovative Research supplies human and animal blood products, sera, and plasma to research and diagnostic customers, overlapping with Quad Five's core product lines in animal-derived biological reagents.
• Pel-Freez Biologicals: Pel-Freez produces animal-derived biological products including blood, serum, plasma, and tissues for research and diagnostic use, with comparable custom processing and species breadth to Quad Five.
• Valley Biomedical: Valley Biomedical specializes in human and animal blood products, sera, and antisera for diagnostics and research, directly competing in the same specialty biologicals niche as Quad Five.
• Equitech-Bio: Equitech-Bio manufactures animal serum products (bovine, equine, goat, sheep) for cell culture and diagnostics, with a directly overlapping product portfolio and customer base to Quad Five.
• Rockland Immunochemicals: Rockland produces antibodies and biological reagents including animal-derived products for life science research and diagnostics, with adjacent rather than directly overlapping offerings to Quad Five.

Broad incumbents

• Sigma-Aldrich (Merck KGaA): Sigma-Aldrich/Merck supplies a broad catalog of biological reagents including animal sera and blood products as part of a much larger life sciences portfolio, competing with Quad Five in serum and blood product categories at greater scale.
• Thermo Fisher Scientific: Thermo Fisher is a major life sciences tools and diagnostics company offering sera, blood products, and cell culture reagents through its Gibco and other brands, serving overlapping diagnostic and research customers at significantly greater scale.
• Lonza Group: Lonza is a global leader in cell culture media, sera, and bioprocessing products for pharma and diagnostics, competing with Quad Five in the serum and animal-derived biologicals space with substantially greater scale and capacity.
• Bio-Rad Laboratories: Bio-Rad is a diversified life sciences and clinical diagnostics company whose reagent portfolio includes blood-based products and controls that overlap with Quad Five's diagnostic customer use cases.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/quad-five

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Quad Five