Stilmas

What Stilmas does

Stilmas S.p.A., founded in 1912 in Italy and headquartered in Settala (Milan), designs and manufactures clean water technologies and integrated clean utilities systems for the life sciences and advanced technology industries. The company is a wholly-owned subsidiary of Masco Group, which is backed by Germany's RSBG SE. Stilmas' product portfolio spans distillation (multiple-effect Pharmastill MS, vapor compression VCS, thermosyphon-based Pure Steam Generators), membrane technologies (BioPure LSX WFI, Pharma RO, PHARMADION, BIO PURE H2P, PRO-X90, EDI), storage and distribution systems, and turnkey project delivery. It also serves adjacent markets including cosmetics, food and beverage, laboratory, and microelectronics through the UltraPure LSX ME platform launched in 2024.

The company's core technology stack combines proprietary distillation architectures with membrane-based processing and PLC-controlled automation (Allen Bradley CompactLogix, 21-CFR-11 ready), supplemented by the Masco Digital Platform (MDP) for IIoT-enabled remote monitoring and AI-assisted optimization. Validated to USP, EP, and JP pharmacopoeia standards, Stilmas has shipped 6,000+ generation units and 10,000+ single units to 5,000+ clients worldwide, with 3 production sites and 5 sales/service hubs across Italy, China, Germany, Canada, and the USA, supported by 50+ service engineers and 20+ agents.

Stilmas makes money primarily through direct, enterprise-level sales of capital equipment and turnkey systems, complemented by after-sales services (training, revamping, remote service, preventive maintenance, sustainability assessments, facility management) and spare parts. Customers are concentrated in pharmaceutical and biotech manufacturing, with a growing focus on ATMP/cell-and-gene therapy (via parent Masco Group's XILS BV acquisition in 2022) and semiconductor/microelectronics (via UltraPure LSX ME). The go-to-market combines direct global sales offices with event-driven demand generation at ISPE, CPhI, UltraFacility, and PDA forums.

Name

Stilmas

Legal name

Stilmas SpA

Website

https://stilmas.com

Company type

Private

Founded year

1912

Operating status

Operating

Headcount range

101–250 employees

Short description

Stilmas, an Italy-based subsidiary of Masco Group, designs and manufactures clean water generation, storage, and distribution systems (WFI, Purified Water, Pure Steam, UPW) for pharmaceutical, biotech, and microelectronics manufacturers globally, with turnkey projects and lifecycle services.

Ownership category

akta.pro rank

Product category

Pharmaceutical Water Systems

NAICS

Pump and Compressor Manufacturing (33391), Measuring, Dispensing, and Other Pumping Equipment Manufacturing (333914), Power Boiler and Heat Exchanger Manufacturing (332410)

SIC

Pumps & Pumping Equipment (3561), Steam & Air-Conditioning Supply (4961)

akta.pro primary industry

Water Systems & Treatment (Pumps/Boilers/Water Heaters/Filtration) (IMAIABAK)

akta.pro secondary industry

Pump & Compressor Packages (Skids, Booster Sets) (IMAHANAG)

Keywords

• Pharmaceutical water systems
• Purified water generation
• Pure steam generation
• Water for injection equipment
• Ultra-pure water systems

Headquarters

HQ city

Milan

HQ country

Italy

HQ region

Europe

Offices5 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Equipment Sales: Sale of standalone water treatment equipment including WFI generators, PW generators, Pure Steam generators, pretreatment systems, storage and distribution systems
2. After-Sales Services: Comprehensive lifecycle services including training, revamping, remote service, technical assistance, preventive maintenance, sustainability assessments, and facility management
3. Turnkey Systems: Complete integrated project delivery including design, installation, commissioning, validation, and after-sales assistance for clean utilities systems
4. Spare Parts: Supply of recommended spare parts for preventive maintenance and emergency replacements

Go-to-market motion2 records

Distribution channels1 record

Marketing channels7 records

Core offering

Stilmas designs, manufactures, and sells clean water generation, storage, and distribution systems — including Water for Injection (WFI) stills, Purified Water (PW) and Ultra-Pure Water (UPW) units, Pure Steam generators, pretreatment systems, and turnkey clean utilities projects — for pharmaceutical, biotech, cosmetics, food & beverage, laboratory, and microelectronics customers. The company supplements its equipment with lifecycle services including installation, commissioning, validation, preventive maintenance, revamping, remote monitoring, and spare parts.

Product overview

Stilmas is a global provider of clean water technologies and systems for Life Sciences and Advanced Technologies industries. The company offers a comprehensive portfolio of standalone technologies and integrated solutions organized around key product categories: WFI generation (Pharmastill MS, Vapor Compression Still, Membrane-based WFI Generator, BioPure LSX WFI, Pure Steam Condenser), Purified Water generation (Pharma RO, PHARMADION, BioPure LSX USP, VPure 4400H, BioPure H2P), Pure Steam generation (Pure Steam Generator PSG), Pretreatment (PRO-X90, Other Pretreatment Systems), Storage and Distribution (SDS, Turnkey Systems), and Lab/High Purity Water (4400L, 2200L, EDI). UltraPure LSX ME serves the microelectronics/semiconductor market. The product range spans distillation, membrane, and hybrid technologies with IIoT-enabled controls using Allen Bradley CompactLogix PLC. Services include after-sales support, training, revamping, remote monitoring, preventive maintenance, and spare parts. The company is part of Masco Group.

Differentiator

Problem solved

Functional benefit

Products and services

• Pharmastill MS Falling Film Multiple Effect distillation unit producing WFI (Water for Injection) by gravitational separation, achieving log 6 endotoxin reduction. Available in 3 to 10 effects, output 100 to 22,000 lt/h, with steam, electric, or combination heating versions. For pharmaceutical manufacturers requiring USP/EP/JP-compliant WFI.
• Vapor Compression Still (VCS) Distillation system producing WFI using vapor compression technology, available in rising film and falling film configurations. Output 100 to 24,000 liters/hour with electric, steam-heated, or hybrid heating. Falling film version uses 90% less water in the evaporation column with 65% less starting time. For pharma manufacturers seeking energy-efficient WFI generation.
• Membrane-based WFI Generator WFI generation system combining single-pass Reverse Osmosis, cEDI stack, and ultrafiltration hollow-fiber 6000-dalton membranes. Generates 500 to 30,000 liters/hour with AI self-learning algorithms and automatic CIP/sanitization. For pharmaceutical manufacturers using membrane-based water systems.
• BioPure LSX WFI USP-compliant membrane-based WFI generation system producing 2.5 to 100 GPM with up to 95% water recovery. Features automated heat sanitization, Allen Bradley CompactLogix PLC control, and 21-CFR-11 readiness. For pharmaceutical manufacturers requiring validated, audited-ready WFI systems.
• Pure Steam Condenser (PSC) Double Tube Sheet heat exchanger that partially or totally condenses Pure Steam into WFI. Compact unit with automatic temperature regulation, intended for situations where limited WFI is required. For pharmaceutical manufacturers using pure steam loops.
• Pure Steam Generator (PSG) Thermosyphon-based pure steam generator achieving log 5 endotoxin reduction. Output 50 to 6,000 kg/h with 0-100% production flexibility. Available in electric, combi, and sustainable versions with IIoT readiness via MDP platform. For pharmaceutical manufacturers requiring USP/EP/JP-compliant pure steam.
• Pharma RO (Reverse Osmosis) Double-pass Reverse Osmosis system for Purified Water production, 300 to 30,000 l/h. Features automatic CIP, IIoT readiness through MDP platform, and hot water or chemical sanitization options. For pharmaceutical manufacturers requiring USP Purified Water.
• PHARMADION (Reverse Osmosis + EDI) Alternative to double-pass RO combining single-pass Reverse Osmosis with CEDI stage. Generates 500 to 30,000 lt/h of Purified Water with extremely low conductivity. Features automatic CIP and sanitization with hot water or chemical options. For pharmaceutical manufacturers requiring high-purity Purified Water.
• BioPure LSX USP Next-generation USP Purified Water system producing 2.5 to 100 GPM with up to 95% water recovery. Features automated heat sanitization, self-modulating valves, Allen Bradley CompactLogix PLC, and 21-CFR-11 readiness. For pharmaceutical and biotech manufacturers requiring validated PW.
• VPure 4400H Value-engineered automatic hot water sanitizable RO/EDI system meeting USP, EP, and JP Purified Water requirements. Includes integrated storage and delivery with 2.5–10 gpm RO permeate flow rates and 15–30 gpm distribution flow rates. For pharmaceutical manufacturers seeking a cost-effective PW system.
• BioPure H2P Two-pass sanitary automatic heat sanitizable Reverse Osmosis unit with four independent disinfection modes (1st Pass RO, 2nd Pass RO, Distribution, and Point of Use). Built-in electric heater and low noise air compressor. For pharmaceutical manufacturers requiring flexible PW generation.
• PRO-X90 High-efficiency membrane-based pretreatment system based on RO membranes with full IIoT integration. Achieves at least 90% (up to 98%) water recovery. Generates 3 to 50 m3/h of pretreated water with adaptive algorithm for semi-batch operation. For pharmaceutical and industrial facilities seeking high-recovery pretreatment.
• Other Pretreatment Systems Wide range of water pretreatment systems including multimedia filters, softeners, microfiltration, ultrafiltration, organic scavengers, deironing, ion exchange, carbon filters, and UV lamps. Generates 0.5 to 100 m3/h of pretreated water. For pharmaceutical, biotech, and industrial facilities requiring feedwater preparation.
• Storage and Distribution Systems (SDS) Storage and distribution systems minimizing microbial growth, with options for ozonated or hot water sanitizable distribution. Features sanitary distribution pumps on VFDs, online real-time TOC analyzer, and full validation packages including FAT, SAT, and IQOQ. For pharmaceutical facilities requiring validated WFI/PW distribution loops.
• Turnkey Systems Complete turnkey solutions for clean utilities including basic and detailed engineering, construction, installation, start-up, and full qualification support (DQ, IQ, OQ, PQ). Includes preparation areas, sterile filtration, and integrated automation. For pharmaceutical and biotech customers building or expanding manufacturing facilities.
• 4400L Compact High Purity Water system producing up to 10 US GPM of pure water with storage and delivery up to 80 US GPM. USP, ASTM, NCCLS compliant with optional EDI on the generation skid. For laboratory and small-scale pharmaceutical applications.
• 2200L Compact Low Volume High Purity Water system producing up to 1.5 US GPM to storage with delivery up to 10 US GPM. Single skid polypropylene design with USP, ASTM Type 2/3/4, and NCCLS compliance. For laboratory and low-volume applications.
• EDI (Electrodeionisation) Chemical-free electrodeionisation system with flow rates from 2.5 to 160 USGPM. Features no regeneration chemicals, no hazardous waste stream, and available in sanitary plastic or 316L SS construction. For pharmaceutical and industrial customers requiring high-purity water without chemical regeneration.
• UltraPure LSX ME ASTM D5127 and SEMI F63-0521 compliant Ultra-Pure Water generation system for microelectronics. Available in 25 to 600 GPM platforms with up to 98% automatic variable recovery, Allen Bradley CompactLogix PLC control, and hot water sanitization. For semiconductor and microelectronics manufacturers requiring ultra-pure water.
• After Sales Services Comprehensive lifecycle services including training, revamping, remote service, technical assistance, preventive maintenance, sustainability assessments, and Clean Utilities facility management. For installed base of Stilmas customers across pharmaceutical, biotech, and other industries.
• Spare Parts Recommended and emergency spare parts with critical spares packages based on experience with thousands of plants. Internal stock of critical spare parts selected through statistical analysis of common criticalities. For Stilmas installed base across pharmaceutical, biotech, and other industries.

Quantifiable outcome

• Up to 98% water recovery in UltraPure LSX ME systems
• +5 more outcomes

Segments7 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability3 records

Feature6 records

Partnerships

Two partnerships are on record, tiered core.

• XILS BVcoreStrategic or Co-development Partner · 8 December 2022Masco Group (Stilmas' parent) acquired majority stake in XILS BV, a Belgian engineering firm specializing in ATMPs, cell and gene therapy applications, and cellular agriculture. XILS operates through VILS and BILS subsidiaries. Deal expands Masco Group's capabilities in biotech industry, engineering services and EPC product offerings, particularly in Northern Europe.
• VILS / BILScoreStrategic or Co-development PartnerSubsidiaries of XILS BV - VILS focuses on process engineering for cell and gene therapy, BILS provides turnkey EPC solutions. Active in Western Europe with branches in Netherlands and Switzerland.

Scale indicators8 records

Recent moves11 records

Expansion highlights6 records

Direct peers

• Alfa Laval: Alfa Laval supplies heat exchangers, separation equipment and hygienic process components widely used in pharmaceutical and biotech water/steam systems. Its high-purity and hygienic product portfolio directly overlaps with Stilmas's distillation and heat-transfer equipment.
• GEA Group (Pharma & Healthcare division): GEA designs and supplies process equipment and complete lines for pharmaceutical and biotech manufacturing, including water and steam systems, separators and homogenizers. It overlaps directly with Stilmas in clean utilities for regulated life-sciences customers.
• Pall Corporation (Danaher): Pall provides filtration, separation and purification solutions for pharmaceutical, biotech and microelectronics customers, including integrated UPW and bioprocess water systems. It is a direct competitor to Stilmas in regulated water-purification equipment.
• Evoqua Water Technologies: Evoqua (now part of Veolia) is a specialist in water and wastewater treatment systems, including high-purity water for pharma, biotech and microelectronics. It competes head-to-head with Stilmas on WFI, PW and UPW equipment and aftermarket service.

Broad incumbents

• Thermo Fisher Scientific: Thermo Fisher supplies lab-water purification systems, bioprocess equipment and pharma services globally through its Life Sciences and Laboratory Products segments. It is comparable to Stilmas in regulated lab-water and bioprocess water but operates at much larger scale and broader scope.
• SUEZ Water Technologies & Solutions: SUEZ (incorporating the former GE Water & Process Technologies) supplies water treatment systems, WFI/PW generators and service to pharmaceutical and industrial customers globally. It is one of Stilmas's principal competitors in pharma-grade water systems.
• Merck MilliporeSigma (Life Science): Merck's Life Science division supplies bioprocessing, filtration and water-purification systems (including Milli-Q and related platforms) to pharma, biotech and laboratory customers. It competes with Stilmas in UPW and lab-water segments as part of a much broader consumables and equipment portfolio.
• Veolia Water Technologies (Veolia Environnement): Veolia's Water Technologies division is one of the world's largest suppliers of water treatment and process-water systems, including WFI, PW and high-purity solutions for pharmaceutical, biotech and microelectronics customers — directly comparable product lines and customer base to Stilmas, but at significantly larger scale and scope.

Regional players

• Organo Corporation: Organo is a Japanese specialist in industrial and pharmaceutical pure-water systems (WFI, PW, UPW). It is comparable to Stilmas in product scope and customer type but primarily serves Japan and broader Asia rather than Europe and North America.

Emerging players

• Skalar Analytical: Skalar is a smaller, specialized supplier of wet-chemistry and laboratory/process analyzers used in pharma and industrial QC, including online TOC and conductivity analyzers complementary to Stilmas's Storage & Distribution Systems. It is an adjacent rather than head-to-head competitor but shares Stilmas's regulated-pharma customer base.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/stilmas-spa

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Stilmas