What SCIREQ does

SCIREQ, founded in 1997 and headquartered in Montreal, designs and manufactures specialized laboratory instrumentation for preclinical respiratory research. The company's core platform — anchored by the flexiVent, which uses the Forced Oscillation Technique to quantify lung mechanics across multiple animal species — is positioned as the reference standard in in vivo respiratory phenotyping. Complementary instruments cover the full experimental workflow: inExpose for nose-only and whole-body inhalation exposure (aerosols, cigarette smoke, pollutants, dry powders, biologics), vivoFlow+ for non-invasive plethysmography, expoCube for air-liquid interface in vitro/ex vivo aerosol deposition using thermophoresis, and physioLens for automated Precision Cut Lung Slice imaging. The portfolio is paired with proprietary software (flexiWare, IOX2) and validated integrations to third-party tools (Epithelix and MatTek tissue models, Precisionary slicers, Aeroneb nebulizers, DSI telemetry, micro-CT), enabling combined in vivo, ex vivo, and in vitro studies under the 3Rs framework.

SCIREQ sells through a consultative direct enterprise field-sales motion with application specialists, supplemented by an international distributor network, operating on a quote-based model with 'Request a Quote' and 'Request a web demo' CTAs. Revenue is generated from hardware sales, proprietary software licenses (e.g., flexiWare 8), and ongoing technical support and services. The customer base spans 1,750 research institutions with 7,600 systems deployed worldwide, including pharmaceutical and biotechnology companies (Moderna, Merck, AstraZeneca, Eli Lilly, AbbVie), academic medical centers (Stanford, Johns Hopkins, Harvard, McGill), healthcare providers (Mayo Clinic, National Jewish Health), contract research organizations (Charles River, Battelle), and government agencies (Health Canada).

The company is closely affiliated with emka TECHNOLOGIES (France), which extends the catalog into cardiovascular and neuroscience instrumentation (easyTEL+, emkaPACK5, ecgTUNNEL, emkaBATH, emkaMYO, isolatedHEART, perfusion systems) and provides a European operational footprint. SCIREQ is privately held, employs 11–50 people, and has not disclosed revenue, funding rounds, or M&A activity.

Name

SCIREQ

Legal name

SCIREQ

Website

https://scireq.com

Company type

Private

Founded year

1997

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Product category

Preclinical Respiratory Research Equipment

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

SIC

Laboratory Analytical Instruments (3826)

akta.pro primary industry

Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE)

Keywords

• Preclinical respiratory equipment
• Lung function measurement
• Inhalation exposure systems
• Plethysmography devices
• Precision cut lung slices

Headquarters

HQ city

Montreal

HQ country

Canada

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Scientific Hardware Equipment Sales: Sale of specialized preclinical respiratory research equipment including flexiVent, inExpose, vivoFlow+, expoCube, and physioLens systems along with accessories and configurations.
2. Proprietary Software Licenses: flexiWare software platform for operating and analyzing data from SCIREQ instruments, with version upgrades such as flexiWare 8.
3. Technical Support and Services: Application specialists provide consultation, custom literature searches, and ongoing technical support services.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels7 records

Core offering

SCIREQ manufactures and sells specialized preclinical respiratory research equipment, including the flexiVent lung function measurement system, inExpose inhalation exposure system, vivoFlow+ plethysmographs, expoCube in vitro/ex vivo exposure system, and physioLens automated microscopy platform for Precision Cut Lung Slices. The hardware is paired with proprietary software (flexiWare, IOX2) for data acquisition and analysis, serving pharmaceutical companies, academic research institutions, CROs, healthcare providers, and government agencies.

Product overview

SCIREQ offers a comprehensive portfolio of preclinical respiratory research equipment and integrated solutions. The core product suite includes the flexiVent (gold standard in vivo lung function measurement), inExpose (compact modular inhalation exposure system), vivoFlow+ (plethysmography for breathing patterns), expoCube (air-liquid interface in vitro exposure), and physioLens (automated microscopy for Precision Cut Lung Slices). These systems work together to enable complete in vivo, ex vivo, and in vitro respiratory studies from inhalation exposure through detailed lung function analysis. The portfolio also encompasses emka Technologies cardiovascular solutions including emkaBATH tissue baths, emkaMYO myographs, isolatedHEART systems, Perfusion Systems, and telemetry products (easyTEL+, emkaPACK5, ecgTUNNEL), extending capabilities into cardiovascular and neuroscience research. With 7,600 systems deployed worldwide across 1,750+ institutions supporting 10,000+ publications, SCIREQ provides integrated platforms for drug development, disease modeling, and therapeutic research across respiratory, cardiovascular, and neurological domains.

Differentiator

Problem solved

Functional benefit

Brands

• flexiVent: Gold standard in vivo lung function measurement system for preclinical respiratory mechanics research, compatible with mice, rats, hamsters, rabbits, ferrets, and non-human primates.
• inExpose
• vivoFlow+
• expoCube
• physioLens

Products and services

• flexiVent Gold standard in vivo lung function measurement system using the forced oscillation technique for comprehensive respiratory mechanics, including resistance, compliance, lung volumes, PV loops, and FEV/FVC measurements across mice, rats, hamsters, rabbits, ferrets, and non-human primates. Used by pharmaceutical companies, academic research institutions, and government agencies for preclinical respiratory research.
• inExpose Compact modular inhalation exposure system designed for nose-only and whole-body rodent exposure, supporting aerosol, cigarette smoke, e-cigarette, pollutant, dry powder, and biologic exposures with automated generation and atmospheric monitoring. Used for preclinical inhalation toxicology and respiratory drug delivery studies.
• vivoFlow+ Plethysmography system providing non-invasive breathing pattern measurements in whole body, head-out, and double chamber configurations for conscious spontaneously breathing subjects, measuring minute volume, breathing frequency, and peak flows. Targets respiratory researchers studying breathing patterns in conscious animals.
• expoCube Air-liquid interface (ALI)/Transwell in vitro and ex vivo exposure system that uses thermophoresis technology to deposit aerosols onto cells and tissues, increasing deposition rates from 2% to nearly 40%, with Quartz Crystal Microbalance integration for real-time dose measurement. Used by inhalation scientists studying drug and particle impacts on airway tissues.
• physioLens Turnkey automated microscopy and dosing platform for Precision Cut Lung Slices (PCLS) research, combining high-speed imaging, 3-channel fluorescent microscopy, and precision 3-axis positioning for airway contractility, dose response, cilia beating, and calcium imaging studies. Used by pulmonary and respiratory researchers performing ex vivo tissue analysis.
• emkaBATH Tissue bath system for studying tissue contractility and relaxation responses in isolated tissues, supporting cardiovascular and respiratory research applications.
• emkaMYO Myograph system for studying functional response and vascular reactivity in isolated tissue preparations, supporting cardiovascular research.

Quantifiable outcome

• 10,000+ scientific publications
• +2 more outcomes

Named customers14 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration14 records

Feature5 records

Partnerships

Two partnerships are on record, tiered core.

• Fraunhofer ITEMcoreStrategic or Co-development PartnerSCIREQ and Fraunhofer ITEM have joined forces to develop better research instruments for inhalation scientists. The partnership focuses on the expoCube system for studying impacts of drugs and airborne particles on cells and tissues cultured at air-liquid interface.
• emka TECHNOLOGIEScoreOthersParent/affiliated company providing complementary cardiovascular and neuroscience research equipment including easyTEL+ telemetry, emkaPACK5, ecgTUNNEL, emkaBATH tissue baths, emkaMYO myographs, and isolatedHEART perfusion systems. SCIREQ and emka share the same corporate family with linked websites (scireq.com and emka.fr).

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Data Sciences International (DSI) / Buxco: DSI (formerly Buxco) is the most direct competitor to SCIREQ in preclinical respiratory plethysmography and lung function measurement, offering the FinePointe and other whole-body/head-out plethysmography systems. Both target the same pharma, CRO, and academic pulmonary research customers with overlapping measurement capabilities, including SCIREQ's explicit integration with DSI telemetry.
• emka TECHNOLOGIES: emka TECHNOLOGIES is the affiliated/sister company sharing SCIREQ's website navigation, branding, and product portfolio for cardiovascular (emkaBATH, emkaMYO, isolatedHEART) and neuroscience (easyTEL+, emkaPACK5, ecgTUNNEL) preclinical research. Comparable because both sell specialized physiological measurement instruments to the same pharma/academic preclinical research buyers.
• Copley Scientific: Copley Scientific manufactures inhalation testing equipment for pharmaceutical and academic respiratory drug delivery research, including cascade impactors and aerosol dosing systems. Directly comparable as a specialty inhalation/aerosol exposure equipment provider serving similar pharma OINDP (Orally Inhaled Nasal Drug Product) development customers as SCIREQ's inExpose and expoCube.
• TSE Systems: TSE Systems manufactures behavioral, metabolic, and respiratory research equipment for preclinical rodent studies, including plethysmography and inhalation exposure systems. Comparable as a German-headquartered specialty competitor in the same preclinical respiratory and inhalation research equipment category.
• Panlab / Harvard Bioscience: Panlab (now part of Harvard Bioscience) produces physiological and behavioral research equipment including plethysmography and related respiratory measurement tools. Comparable as a specialty competitor in preclinical respiratory and physiological measurement equipment with similar European academic and pharma customer base.
• EMKA Technologies / emka TECHNOLOGIES (FR): emka TECHNOLOGIES (FR) is the French operating entity directly linked to SCIREQ's website, providing cardiovascular and neuroscience telemetry, tissue bath, and myograph systems. Comparable as the affiliated entity sharing SCIREQ's distribution channels and overlapping pharma/academic customer base in preclinical research instrumentation.

Broad incumbents

• Harvard Bioscience: Harvard Bioscience is a broad life-science tools platform that owns multiple preclinical instrument brands (including legacy Buxco respiratory assets). Comparable as a larger, diversified incumbent in the same preclinical research equipment category with overlapping respiratory and physiological measurement offerings.

Emerging players

• IITC Life Science: IITC Life Science manufactures preclinical physiological measurement instruments including non-invasive blood pressure, metabolic, and respiratory monitoring systems for rodents. Comparable as a smaller specialty player in the same preclinical respiratory and cardiovascular instrumentation niche with overlapping rodent research customers.

Regional players

• Penlon (Respiratory/Preclinical): Penlon produces respiratory and anesthesia equipment with overlap into preclinical/ventilator research applications. Comparable as a respiratory-focused equipment manufacturer, though primarily focused on clinical rather than preclinical use cases, providing an adjacent reference point for SCIREQ's ALI/ARDS and ventilator research offerings.

Others

• MatTek Corporation: MatTek supplies preplated human tissue models (EpiAirway, EpiAlveolar, EpiDerm) that are explicitly compatible with SCIREQ's expoCube in vitro exposure system. Comparable as an enabling ecosystem partner whose tissue models are commonly consumed alongside SCIREQ's equipment in respiratory in vitro research workflows.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/scireq
• Xx.com/SCIREQ

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SCIREQ