Endogen
Endogen is a São Paulo-based Brazilian healthtech commercializing Swiss-standard prescription medical cannabis (Zion Medpharma Full Spectrum) and a clinical nutrition line (Drops, Caps, Powder) via physicians, nutritionists, pharmacies, and an exclusive CannDoc PBM partnership.
- Company typePrivate
- Founded2023
- HeadquartersSão Paulo, Brazil
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Endogen does
Endogen is a privately held Brazilian healthtech, headquartered in São Paulo, that commercializes two integrated product lines: prescription medical cannabis products and clinical nutrition supplements. The cannabis line is anchored by Zion Medpharma Full Spectrum extract (CBD 50 mg/mL, THC <2 mg/mL) manufactured under Swiss pharmaceutical-grade ethanol extraction with batch-level Certificate of Analysis (COA) traceability, sold under Brazilian regulatory framework RDC 327/2019 and Portaria 344/99 via Receita Azul B2 prescription. The nutrition line, branded Endogen Clinical, is organized around a proprietary '10 Pilares do Equilíbrio Nutricional' framework and delivered in three formats — Drops (liquid), Caps (Softgel / Veg Caps / Liquid Capsule Technology) with internationally validated ingredients such as Verisol, Peptan, C-Pure, Promitor, Neumentix, and DHA/EPA, and Powder (collagen, fiber, amino acid, and micronutrient blends).
The company operates a B2B2C go-to-market in which physicians and nutritionists are the primary demand drivers, supported by a dedicated prescriber portal (Área do Prescritor) that delivers technical content and clinical practice support. Products reach patients through Brazilian pharmacy networks and an official e-commerce store. The exclusive CannDoc PBM partnership provides an integrated prescription-to-pharmacy journey with cost-sustainability programs aimed at long-term adherence. Distribution is domestic-only, with current geographic focus on Southeast Brazil.
Commercially, Endogen generates revenue through one-time product sales (cannabis and nutritional supplements) rather than subscriptions, with no public pricing disclosed. The company is led by CEO Lukas Fischer (co-founder of Zion Medpharma, founder of Nature Lab) and benefits from a credentialed board including Hospital Albert Einstein Board President Claudio Lottenberg and former ANVISA Director-President Dirceu Barbano as Chief Regulatory Officer, providing meaningful regulatory and clinical credibility. The company was founded in 2023 and has secured an initial funding round from healthcare-focused investor Green Rock in early 2024.
Endogen firmographics
Firmographics- Name
- Endogen
- Legal name
- Endogen
- Website
- https://endogen.com.br
- Company type
- Private
- Founded year
- 2023
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Endogen is a São Paulo-based Brazilian healthtech commercializing Swiss-standard prescription medical cannabis (Zion Medpharma Full Spectrum) and a clinical nutrition line (Drops, Caps, Powder) via physicians, nutritionists, pharmacies, and an exclusive CannDoc PBM partnership.
- Ownership category
- akta.pro rank
Endogen industry classification
Industry- Product category
- Medical Cannabis & Clinical Nutrition
- NAICS
- Pharmaceutical Preparation Manufacturing (325412)
- SIC
- Pharmaceutical Preparations (2834)
- akta.pro primary industry
- Cannabis Dispensary + Pharmacy/Clinical Model (Patient Services) (CRANAFAI)
- akta.pro secondary industry
- Tobacco, Alcohol & Cannabis Omnichannel (CRAFAEAM)
Keywords
Where Endogen is headquartered
LocationHeadquarters
- HQ city
- São Paulo
- HQ country
- Brazil
- HQ region
- Latin America
Offices1 record
Markets served
Endogen business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Technology or R&D, Marketing or Sales, Personnel, Operations
Revenue model
- Cannabis Medicinal Products: Prescription-based cannabis medicinal products sold through pharmacies and direct-to-patient e-commerce, requiring Receita Azul B2 medical prescription. Revenue generated from product sales with batch-level COA certification and Swiss pharmaceutical quality standards.
- Clinical Nutrition Supplements: Endogen Clinical line of nutritional supplements sold through pharmacy networks and official online store. Products available in three formats: Drops (liquid supplements), Caps (softgel/veg caps/liquid capsule), and Powder (collagen, fiber, amino acids). Integrated approach with cannabis medicinal for synergistic therapeutic outcomes.
Go-to-market motion2 records
Distribution channels2 records
Marketing channels1 record
Endogen product offering
Product offeringCore offering
Endogen is a Brazilian healthtech that develops and sells two integrated product lines: medical cannabis products (Zion Medpharma Full Spectrum cannabis extract with CBD 50mg/mL and THC under 2mg/mL, manufactured under Swiss pharmaceutical standards) and clinical nutrition supplements (Endogen Clinical line in Drops, Caps, and Powder formats). Products require medical prescription (Receita Azul B2) and are distributed through pharmacy networks and an official e-commerce store, targeting the Endocannabinoid System (SEC) for therapeutic outcomes.
Product overview
Endogen is a Brazilian healthtech offering two integrated product lines: medical cannabis products and clinical nutrition supplements. The cannabis line features Zion Medpharma Full Spectrum oil (CBD 50mg/mL, THC <2mg/mL) manufactured under Swiss pharmaceutical standards. The Endogen Clinical nutrition line includes three sub-lines: Drops (liquid supplements with rapid absorption), Caps (capsules with Softgel/Veg Caps/Liquid Capsule Technology), and Powder (collagen and fiber-based supplements). These products are designed to work synergistically by modulating the Endocannabinoid System (SEC), with nutrition and phytocannabinoids complementing each other for therapeutic outcomes.
Differentiator
Problem solved
Functional benefit
Products and services
- Zion Medpharma Full Spectrum Medical cannabis oil formulation with CBD 50 mg/mL and THC less than 2 mg/mL, utilizing full spectrum extract technology with cannabinoid and terpene entourage effect for enhanced therapeutic efficacy. Requires medical prescription (Receita Azul B2).
- Endogen Clinical - Linha Drops Liquid supplements with rapid absorption focused on sleep, immunity, energy, and neurophysiological support, featuring selected aromatic terpenes that synergize with medical cannabis treatment.
- Endogen Clinical - Linha Caps Capsule supplements utilizing Softgel, Veg Caps, and Liquid Capsule Technology to ensure higher bioavailability and stability of active ingredients across multiple pillars of nutritional balance.
- Endogen Clinical - Linha Powder Powder supplements formulated with collagens (Verisol, Peptan, C-Pure), fibers (Promitor, polidextrose, inulin), amino acids, proteins, and essential micronutrients supporting health maintenance and nutritional balance.
Companies that use Endogen
Customer profileSegments2 records
Ideal customer profiles2 records
Endogen technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
Endogen partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core.
- CannDoccoreCannDoc is the exclusive PBM (Programa de Benefício em Medicamentos) and digital platform partner of Endogen, functioning as an integrated patient journey platform connecting physicians, patients, and pharmacies. Beyond traditional medication benefit programs, CannDoc provides therapeutic sustainability through cost reduction ensuring long-term treatment continuity, complete prescription journey support for physicians, specialized patient guidance for correct usage and adherence, and integrated pharmacy access for simplified product acquisition.
- Zion MedpharmacoreZion Medpharma is the Swiss pharmaceutical manufacturer supplying Endogen's Full Spectrum cannabis extract products. The manufacturing uses ethanol extraction in advanced rotary evaporator systems under rigorous European pharmaceutical standards, ensuring non-residual solvents, maximum preservation of phytocannabinoid and terpene profiles, and volatile reincorporation for enhanced therapeutic efficacy and clinical predictability.
Scale indicators1 record
Recent moves6 records
Expansion highlights5 records
Endogen competitors and assessment
Company assessmentDirect peers
- AB Brazil (Associação Brasileira de Cannabis Medicinal) / Greencann: Brazilian medical cannabis patient-services and product platform focused on prescription fulfillment through partner pharmacies. Comparable business model combining clinical patient services with prescription cannabis products.
- Prati-Donaduzzi: Brazilian pharmaceutical company with a dedicated medical cannabis line (Cannazil) sold through pharmacies under ANVISA regulation. Directly comparable as a domestic pharmaceutical-grade cannabis brand targeting prescription-based distribution channels in Brazil.
- Entourage Phytolab: Brazilian healthtech specializing in medical cannabis products with a focus on physician education and pharmacy distribution. Comparable as a clinical-pharmacy cannabis brand operating under RDC 327/2019 with similar prescriber-led go-to-market.
Broad incumbents
- Aurora Cannabis: Global medical cannabis company with established international distribution including into Brazil via partnerships. Comparable as a regulated medical cannabis brand pursuing physician-driven prescription channels.
- Cronos Group: Global cannabis company with a foothold in Latin American markets through branded medical cannabis products. Comparable in regulated medical cannabis distribution model targeting pharmacies and physicians.
- Canopy Growth Corporation: Canadian medical cannabis producer with international footprint including emerging Latin American markets. Comparable in regulated medical cannabis manufacturing and distribution, though Endogen focuses on integrated nutrition-cannabis synergy.
- Tilray Brands: Global medical cannabis leader with operations across multiple countries including Latin America. Comparable as a multi-country medical cannabis producer and brand serving prescription channels, though Tilray operates at much larger scale and broader portfolio.
Others
- SalomãoZoppi Diagnósticos (DASA-acquired): Brazilian diagnostics company co-founded by Endogen board members Dr. Luiz Salomão and Dr. Paulo Zoppi. Comparable as a Brazilian healthtech founded and led by the same investor-physician network now backing Endogen, illustrating the ecosystem.
Emerging players
- Zion Medpharma: Swiss pharmaceutical manufacturer of cannabis extracts and Endogen's primary supply partner. Comparable as a pharmaceutical-grade cannabis extractor but operates as Endogen's supplier rather than a direct competitor in the Brazilian market.
- Flora (parent of Francis, OX, Neutrox): Major Brazilian consumer goods company with significant pharmacy-channel presence; Daniel Tiraboschi (Endogen Commercial Business Consultant) is Director of Businesses at Flora. Comparable adjacency in pharmacy-channel nutritional supplements and personal care, though Flora does not operate in medical cannabis.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
Endogen compliance and trust
Trust signalCompliance2 records
Endogen financial estimates
Financial estimateRevenue estimate
Valuation estimate
Endogen leadership team
Management profileNumber of profiles
Profiles7 records
Endogen funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Endogen M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Endogen
What does Endogen do?
Endogen is a Brazilian healthtech that develops and sells two integrated product lines: medical cannabis products (Zion Medpharma Full Spectrum cannabis extract with CBD 50mg/mL and THC under 2mg/mL, manufactured under Swiss pharmaceutical standards) and clinical nutrition supplements (Endogen Clinical line in Drops, Caps, and Powder formats). Products require medical prescription (Receita Azul B2) and are distributed through pharmacy networks and an official e-commerce store, targeting the Endocannabinoid System (SEC) for therapeutic outcomes.
Is Endogen a public or private company?
Endogen is a private company. It is classified as venture growth investor backed and is currently operating.
When was Endogen founded?
Endogen was founded in 2023. It employs 11 to 50 people.
Where is Endogen based?
Endogen is headquartered in São Paulo, Brazil, in the Latin America region.
How does Endogen make money?
Two revenue lines are on record. Cannabis Medicinal Products are the primary driver. The others are clinical Nutrition Supplements.
Who are Endogen's main competitors?
Direct peers on record are AB Brazil (Associação Brasileira de Cannabis Medicinal) / Greencann, Prati-Donaduzzi and Entourage Phytolab. Broad incumbents are Aurora Cannabis, Cronos Group, Canopy Growth Corporation and Tilray Brands. SalomãoZoppi Diagnósticos (DASA-acquired) is listed as an others. Emerging players are Zion Medpharma and Flora (parent of Francis, OX, Neutrox).
Does Endogen have an API?
No public API is recorded for Endogen.
What industry is Endogen in?
Endogen's product category is Medical Cannabis & Clinical Nutrition. Its primary akta.pro industry code is CRANAFAI, Cannabis Dispensary + Pharmacy/Clinical Model (Patient Services), with a secondary code of CRAFAEAM, Tobacco, Alcohol & Cannabis Omnichannel. Its NAICS code is 325412 and its SIC code is 2834.