Endogen

What Endogen does

Endogen is a privately held Brazilian healthtech, headquartered in São Paulo, that commercializes two integrated product lines: prescription medical cannabis products and clinical nutrition supplements. The cannabis line is anchored by Zion Medpharma Full Spectrum extract (CBD 50 mg/mL, THC <2 mg/mL) manufactured under Swiss pharmaceutical-grade ethanol extraction with batch-level Certificate of Analysis (COA) traceability, sold under Brazilian regulatory framework RDC 327/2019 and Portaria 344/99 via Receita Azul B2 prescription. The nutrition line, branded Endogen Clinical, is organized around a proprietary '10 Pilares do Equilíbrio Nutricional' framework and delivered in three formats — Drops (liquid), Caps (Softgel / Veg Caps / Liquid Capsule Technology) with internationally validated ingredients such as Verisol, Peptan, C-Pure, Promitor, Neumentix, and DHA/EPA, and Powder (collagen, fiber, amino acid, and micronutrient blends).

The company operates a B2B2C go-to-market in which physicians and nutritionists are the primary demand drivers, supported by a dedicated prescriber portal (Área do Prescritor) that delivers technical content and clinical practice support. Products reach patients through Brazilian pharmacy networks and an official e-commerce store. The exclusive CannDoc PBM partnership provides an integrated prescription-to-pharmacy journey with cost-sustainability programs aimed at long-term adherence. Distribution is domestic-only, with current geographic focus on Southeast Brazil.

Commercially, Endogen generates revenue through one-time product sales (cannabis and nutritional supplements) rather than subscriptions, with no public pricing disclosed. The company is led by CEO Lukas Fischer (co-founder of Zion Medpharma, founder of Nature Lab) and benefits from a credentialed board including Hospital Albert Einstein Board President Claudio Lottenberg and former ANVISA Director-President Dirceu Barbano as Chief Regulatory Officer, providing meaningful regulatory and clinical credibility. The company was founded in 2023 and has secured an initial funding round from healthcare-focused investor Green Rock in early 2024.

Name

Endogen

Legal name

Endogen

Website

https://endogen.com.br

Company type

Private

Founded year

2023

Operating status

Operating

Headcount range

11–50 employees

Short description

Endogen is a São Paulo-based Brazilian healthtech commercializing Swiss-standard prescription medical cannabis (Zion Medpharma Full Spectrum) and a clinical nutrition line (Drops, Caps, Powder) via physicians, nutritionists, pharmacies, and an exclusive CannDoc PBM partnership.

Ownership category

akta.pro rank

Product category

Medical Cannabis & Clinical Nutrition

NAICS

Pharmaceutical Preparation Manufacturing (325412)

SIC

Pharmaceutical Preparations (2834)

akta.pro industry

PRIMARYCRANAFAI

Cannabis Dispensary + Pharmacy/Clinical Model (Patient Services)

Consumer Products & Retail/Tobacco, Alcohol & Cannabis Retail/Cannabis Dispensaries (Adult-Use & Medical)

SECONDARYCRAFAEAM

Tobacco, Alcohol & Cannabis Omnichannel

Consumer Products & Retail/E-commerce & Marketplaces/Omnichannel Retail E-commerce

Keywords

• Medical cannabis products
• Clinical nutrition supplements
• Pharmaceutical-grade extracts
• Cannabinoid therapeutics
• Preventive health supplements

Headquarters

HQ city

São Paulo

HQ country

Brazil

HQ region

Latin America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Marketing or Sales, Personnel, Operations

Revenue model

1. Cannabis Medicinal Products: Prescription-based cannabis medicinal products sold through pharmacies and direct-to-patient e-commerce, requiring Receita Azul B2 medical prescription. Revenue generated from product sales with batch-level COA certification and Swiss pharmaceutical quality standards.
2. Clinical Nutrition Supplements: Endogen Clinical line of nutritional supplements sold through pharmacy networks and official online store. Products available in three formats: Drops (liquid supplements), Caps (softgel/veg caps/liquid capsule), and Powder (collagen, fiber, amino acids). Integrated approach with cannabis medicinal for synergistic therapeutic outcomes.

Go-to-market motion2 records

Distribution channels2 records

Marketing channels1 record

Core offering

Endogen is a Brazilian healthtech that develops and sells two integrated product lines: medical cannabis products (Zion Medpharma Full Spectrum cannabis extract with CBD 50mg/mL and THC under 2mg/mL, manufactured under Swiss pharmaceutical standards) and clinical nutrition supplements (Endogen Clinical line in Drops, Caps, and Powder formats). Products require medical prescription (Receita Azul B2) and are distributed through pharmacy networks and an official e-commerce store, targeting the Endocannabinoid System (SEC) for therapeutic outcomes.

Product overview

Endogen is a Brazilian healthtech offering two integrated product lines: medical cannabis products and clinical nutrition supplements. The cannabis line features Zion Medpharma Full Spectrum oil (CBD 50mg/mL, THC <2mg/mL) manufactured under Swiss pharmaceutical standards. The Endogen Clinical nutrition line includes three sub-lines: Drops (liquid supplements with rapid absorption), Caps (capsules with Softgel/Veg Caps/Liquid Capsule Technology), and Powder (collagen and fiber-based supplements). These products are designed to work synergistically by modulating the Endocannabinoid System (SEC), with nutrition and phytocannabinoids complementing each other for therapeutic outcomes.

Differentiator

Problem solved

Functional benefit

Products and services

• Zion Medpharma Full Spectrum Medical cannabis oil formulation with CBD 50 mg/mL and THC less than 2 mg/mL, utilizing full spectrum extract technology with cannabinoid and terpene entourage effect for enhanced therapeutic efficacy. Requires medical prescription (Receita Azul B2).
• Endogen Clinical - Linha Drops Liquid supplements with rapid absorption focused on sleep, immunity, energy, and neurophysiological support, featuring selected aromatic terpenes that synergize with medical cannabis treatment.
• Endogen Clinical - Linha Caps Capsule supplements utilizing Softgel, Veg Caps, and Liquid Capsule Technology to ensure higher bioavailability and stability of active ingredients across multiple pillars of nutritional balance.
• Endogen Clinical - Linha Powder Powder supplements formulated with collagens (Verisol, Peptan, C-Pure), fibers (Promitor, polidextrose, inulin), amino acids, proteins, and essential micronutrients supporting health maintenance and nutritional balance.

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Two partnerships are on record, tiered core.

• CannDoccoreChannel Partner/ Reseller/ DistributorCannDoc is the exclusive PBM (Programa de Benefício em Medicamentos) and digital platform partner of Endogen, functioning as an integrated patient journey platform connecting physicians, patients, and pharmacies. Beyond traditional medication benefit programs, CannDoc provides therapeutic sustainability through cost reduction ensuring long-term treatment continuity, complete prescription journey support for physicians, specialized patient guidance for correct usage and adherence, and integrated pharmacy access for simplified product acquisition.
• Zion MedpharmacoreTechnology or IntegrationZion Medpharma is the Swiss pharmaceutical manufacturer supplying Endogen's Full Spectrum cannabis extract products. The manufacturing uses ethanol extraction in advanced rotary evaporator systems under rigorous European pharmaceutical standards, ensuring non-residual solvents, maximum preservation of phytocannabinoid and terpene profiles, and volatile reincorporation for enhanced therapeutic efficacy and clinical predictability.

Scale indicators1 record

Recent moves6 records

Expansion highlights5 records

Direct peers

• AB Brazil (Associação Brasileira de Cannabis Medicinal) / Greencann: Brazilian medical cannabis patient-services and product platform focused on prescription fulfillment through partner pharmacies. Comparable business model combining clinical patient services with prescription cannabis products.
• Prati-Donaduzzi: Brazilian pharmaceutical company with a dedicated medical cannabis line (Cannazil) sold through pharmacies under ANVISA regulation. Directly comparable as a domestic pharmaceutical-grade cannabis brand targeting prescription-based distribution channels in Brazil.
• Entourage Phytolab: Brazilian healthtech specializing in medical cannabis products with a focus on physician education and pharmacy distribution. Comparable as a clinical-pharmacy cannabis brand operating under RDC 327/2019 with similar prescriber-led go-to-market.

Broad incumbents

• Aurora Cannabis: Global medical cannabis company with established international distribution including into Brazil via partnerships. Comparable as a regulated medical cannabis brand pursuing physician-driven prescription channels.
• Cronos Group: Global cannabis company with a foothold in Latin American markets through branded medical cannabis products. Comparable in regulated medical cannabis distribution model targeting pharmacies and physicians.
• Canopy Growth Corporation: Canadian medical cannabis producer with international footprint including emerging Latin American markets. Comparable in regulated medical cannabis manufacturing and distribution, though Endogen focuses on integrated nutrition-cannabis synergy.
• Tilray Brands: Global medical cannabis leader with operations across multiple countries including Latin America. Comparable as a multi-country medical cannabis producer and brand serving prescription channels, though Tilray operates at much larger scale and broader portfolio.

Others

• SalomãoZoppi Diagnósticos (DASA-acquired): Brazilian diagnostics company co-founded by Endogen board members Dr. Luiz Salomão and Dr. Paulo Zoppi. Comparable as a Brazilian healthtech founded and led by the same investor-physician network now backing Endogen, illustrating the ecosystem.

Emerging players

• Zion Medpharma: Swiss pharmaceutical manufacturer of cannabis extracts and Endogen's primary supply partner. Comparable as a pharmaceutical-grade cannabis extractor but operates as Endogen's supplier rather than a direct competitor in the Brazilian market.
• Flora (parent of Francis, OX, Neutrox): Major Brazilian consumer goods company with significant pharmacy-channel presence; Daniel Tiraboschi (Endogen Commercial Business Consultant) is Director of Businesses at Flora. Comparable adjacency in pharmacy-channel nutritional supplements and personal care, though Flora does not operate in medical cannabis.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Endogen