ClinicalConnection.com

What ClinicalConnection.com does

ClinicalConnection.com operates a web-based clinical trial patient recruitment platform that connects pharmaceutical sponsors, contract research organizations, and individual research sites with patients and healthy volunteers seeking participation opportunities. The company was founded in 1998 by medical research professionals and is headquartered in Needham, Massachusetts, serving a global partner base of more than 2,000 research organizations with documented operations in the United States, Canada, and the United Kingdom.

The platform is anchored by the proprietary PatientEdge database, which holds over one million registered members who have completed health interest profiles covering 200+ medical conditions, enabling condition- and geography-targeted trial notifications. Around this core asset, the company offers a suite of integrated services: the Clinical Ad Network (a pay-per-click digital advertising network running across search engines and health websites), Patient Direct Mail Alerts (offline recruitment using member postal data), PATIENTSelect (direct-to-patient advertising for non-clinical buyers such as market researchers and patient education providers), SiteConnection (investigator site identification for sponsors and CROs), and tiered Study Listings with optional Virtual Clinical Trial advertising modules. The site attracts more than 250,000 monthly visitors via organic search, and the system delivers real-time referral alerts to research centers when members indicate interest.

ClinicalConnection monetizes through a mix of recurring subscriptions (Basic, Plus, Pro, and Enterprise tiers billed month-to-month with no long-term contracts), usage-based PPC fees, transaction-priced direct mail campaigns, and advertising revenue from PATIENTSelect. The go-to-market is hybrid: a self-service web platform for individual research sites and mid-market customers, supplemented by direct enterprise sales engagement for multicenter studies, CROs, and sponsors with complex, high-volume recruitment needs. The company is privately held, has never disclosed external funding, and operates with a headcount of 11–50 employees.

Name

ClinicalConnection.com

Legal name

ClinicalConnection.com

Website

https://clinicalconnection.com

Company type

Private

Founded year

1998

Operating status

Operating

Headcount range

11–50 employees

Short description

ClinicalConnection.com is a privately held, web-based patient recruitment platform founded in 1998 that connects pharmaceutical sponsors, CROs, and research sites with a proprietary database of over 1 million patients seeking clinical trial participation, monetizing through subscriptions, PPC advertising, and direct mail.

Ownership category

akta.pro rank

Headquarters

HQ city

Newton

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Marketing or Sales, Personnel, Operations, Supply Chain

Revenue model

1. Study Listing Subscriptions: Research sites pay monthly subscription fees to post clinical trial listings and receive patient referrals. Plans include Basic/Standard (listing only), Plus, Pro, and Enterprise tiers with increasing services. Billing is month-to-month with no contracts.
2. Clinical Ad Network PPC Advertising: Pay-per-click digital advertising campaigns where study sponsors and sites pay when someone clicks their targeted study ads. Fees vary by keyword competitiveness and geographic targeting. Included in Plus, Pro, and Enterprise pricing plans.
3. Direct Mail Patient Recruitment: Custom direct mail campaigns targeting specific patient populations in the database. Pricing based on number of relevant patients and includes printing, postage, and mailing services.
4. Multicenter Study Recruitment Services: Services for CROs and sponsors managing trials across multiple sites, including multicenter study listings, newsletter placements, social media marketing, and enhanced digital advertising campaigns.
5. PATIENTSelect Direct-to-Patient Advertising: Non-clinical companies pay to reach specific patient populations for market research, surveys, product testing, patient education, and other approved applications using the PatientEdge database.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

ClinicalConnection operates a web-based patient recruitment platform that connects clinical trial sponsors, CROs, and research sites with potential study participants. Its core asset is the PatientEdge™ database of over 1 million members, complemented by subscription-based study listings, pay-per-click digital advertising through the Clinical Ad Network™, physical direct mail outreach, PATIENTSelect™ direct-to-patient advertising, and SiteConnection investigator site identification services.

Product overview

ClinicalConnection.com operates a web-based clinical trial notification and search platform that connects patients with relevant clinical research opportunities. The platform comprises a core PatientEdge™ member database of over 1 million individuals seeking trial participation, complemented by multiple recruitment service modules including the Clinical Ad Network™ (PPC advertising), Patient Direct Mail Alerts (physical mail outreach), PATIENTSelect™ (direct-to-patient marketing for non-research companies), SiteConnection (investigator site identification), and Study Listings platforms for individual and multicenter trials. The services are designed for research sites, CROs, sponsors, and other recruitment companies seeking to accelerate patient enrollment.

Differentiator

Problem solved

Functional benefit

Brands

• PatientEdge™: Study participant database containing over 1 million members actively seeking clinical trial participation.
• PATIENTSelect™
• Clinical Ad Network™

Products and services

• Study Listings

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Two partnerships are on record, tiered core.

• Science 37coreStrategic or Co-development PartnerScience 37, a leading provider of decentralized clinical trial solutions, partners with ClinicalConnection to expand patient recruitment reach. ClinicalConnection's database complements Science 37's extensive partner network, enabling recruitment across diverse therapeutic areas including respiratory, oncology, and rare disease for underserved populations.
• Research Sites NetworkcoreStrategic or Co-development PartnerClinicalConnection has partnered with thousands of research sites over 20+ years including academic medical centers, community hospitals, physician practices, independent research centers, and site networks. These sites utilize ClinicalConnection's recruitment platform and database to connect with patients and sponsors for clinical trial opportunities.

Scale indicators7 records

Recent moves6 records

Expansion highlights5 records

Market position

Strengths4 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/clincon

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about ClinicalConnection.com