Sequani
Sequani is a UK-based non-clinical contract research organization providing GLP toxicology, bioanalysis, formulation, and pathology services to pharmaceutical, crop protection, and chemical companies for regulatory safety submissions.
- Company typePrivate
- Founded1982
- HeadquartersLedbury, United Kingdom
- Headcount51–100
- GTM typeB2B
- OfferingServices
What Sequani does
Sequani is a UK-based, privately held contract research organization (CRO) specializing in non-clinical safety assessment for the pharmaceutical, crop protection, and chemical industries. Founded in the early 1980s and headquartered in Ledbury, Herefordshire, the company operates a purpose-built facility comprising 820m² of laboratory space and a 910m² modern vivarium, processing over 500,000 histology samples per year with a staff of 51–100. Sequani is structured around three service divisions — Drug Development, Crop Protection, and Chemical Safety — and offers an integrated portfolio covering general, genetic, reproduction, juvenile, and carcinogenicity toxicology, plus pathology, clinical pathology, bioanalysis, toxicokinetics/pharmacokinetics, formulation analysis, biomarkers, and SEND-compliant data services.
The company's core technology stack combines in vivo toxicology study execution under GLP (compliant with OECD, EPA, and JMAFF guidelines) with conventional bioanalytical instrumentation — Sciex LC-MS/MS, Roche cobas, Sysmex hematology analyzers, and Phoenix WinNonLin for PK/PD modeling. Differentiated capabilities include microsampling techniques (≤50 µL blood volumes) deployed across more than 100 studies, a pioneering cross-fostering juvenile toxicology approach reducing animal usage by more than 65% (with 70+ regulatory juvenile studies completed), and the SEND ASSURE service, which guarantees 100% consistency between SEND datasets and final study reports for FDA and PMDA submissions via a partnership with PointCross.
Sequani generates revenue through professional-services contracts on a project-by-project basis, with study fees negotiated based on study complexity, duration, and species used; pricing is not publicly disclosed. The go-to-market is direct enterprise sales supported by dedicated programme managers, with demand generation through industry conferences (SOT, EuroTox, British Toxicology Society), webinars (notably with Medicines Discovery Catapult), scientific publications, and a content-rich website. Customers are large pharmaceutical companies, crop protection product developers, and chemical manufacturers operating in EMEA, with global reach implied by marketing activity though only the UK is listed as an operating geography.
Sequani firmographics
Firmographics- Name
- Sequani
- Legal name
- Sequani Limited
- Website
- https://sequani.com
- Company type
- Private
- Founded year
- 1982
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- Sequani is a UK-based non-clinical contract research organization providing GLP toxicology, bioanalysis, formulation, and pathology services to pharmaceutical, crop protection, and chemical companies for regulatory safety submissions.
- Ownership category
- akta.pro rank
Sequani industry classification
Industry- Product category
- Contract Research Organization (CRO) - Non-Clinical Toxicology
- NAICS
- Testing Laboratories and Services (541380)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)
- akta.pro primary industry
- Toxicology & Safety Assessment CROs (GLP) (HLAGAAAC)
- akta.pro secondary industries
- Laboratory Quality & GLP/GCLP Compliance (HLAGAKAK), GxP Audits & Supplier Qualification (GMP/GCP/GLP/GDP) (HLAGAKAE)
Keywords
Where Sequani is headquartered
LocationHeadquarters
- HQ city
- Ledbury
- HQ country
- United Kingdom
- HQ region
- Europe
Offices1 record
Markets served
Sequani business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales
Revenue model
- Contract Research Services: Sequani generates revenue through providing contract research services including toxicology studies, bioanalysis, formulation sciences, pathology, and pharmacokinetics/toxicokinetics services to pharmaceutical, crop protection, and chemical companies. Studies are conducted on a project-by-project basis with fees based on study complexity, duration, and species used.
Go-to-market motion1 record
Distribution channels1 record
Marketing channels6 records
Sequani product offering
Product offeringCore offering
Sequani is a contract research organization (CRO) providing non-clinical safety assessment services to pharmaceutical, crop protection, and chemical companies. Services span toxicology studies (general, genetic, reproduction, juvenile, carcinogenicity), bioanalysis, formulation sciences, pathology, clinical pathology, toxicokinetics/pharmacokinetics, biomarkers, microsampling, and SEND regulatory data compliance, all delivered under GLP with OECD, EPA, and JMAFF guideline adherence from a custom-designed facility with co-located laboratory and vivarium space.
Product overview
Sequani operates as a contract research organization (CRO) providing non-clinical laboratory services across three divisions: Drug Development, Crop Protection, and Chemical Safety. The company offers an integrated service portfolio encompassing toxicology (general, genetic, reproduction, juvenile, carcinogenicity, investigative), pathology, clinical pathology, bioanalysis, formulation sciences, toxicokinetics/pharmacokinetics, biomarkers, and programme management. Specialized offerings include SEND ASSURE for CDISC data compliance, microsampling techniques for reduced animal use, and REACH regulatory services for chemical safety. Studies are conducted under GLP with OECD, EPA, and JMAFF guideline compliance. The service is delivered through purpose-built laboratory and vivarium facilities with dedicated study directors coordinating cross-functional scientific teams.
Differentiator
Problem solved
Functional benefit
Brands
- SEND ASSURE: A turnkey service that thoroughly checks generated SEND (Standard for Exchange of Nonclinical Data) datasets against the final PDF Study Report, providing 100% guarantee of data consistency and submission quality.
Products and services
- Drug Development Services Comprehensive non-clinical drug development services supporting all phases from lead optimization through Phase III, including toxicology, bioanalysis, pharmacokinetics, formulation sciences, pathology, clinical pathology, biomarkers, microsampling, safety pharmacology, and SEND regulatory submission support. Targeted at pharmaceutical companies developing drug candidates.
- Crop Protection Services
- Chemical Safety Services
- SEND ASSURE
- Reproduction Toxicology Studies
- Juvenile Toxicology Studies
- Carcinogenicity Studies
- REACH Regulation Services
- Bioanalysis Services
- Programme Management Service
Quantifiable outcome
- Animal usage reduction of more than 65% through cross-fostering approach
- +2 more outcomes
Companies that use Sequani
Customer profileSegments3 records
Ideal customer profiles3 records
Sequani technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
Sequani partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered core and minor.
- Medicines Discovery Catapult (MDC)coreCollaborated on MDC Connects Webinar series presenting on nonclinical strategies for First in Man clinical trials, specifically on 'How to get your molecule into humans' with focus on developing nonclinical strategy and enhancing nonclinical efficiency.
- Ellegaard MinipigsminorCollaborative presentation at 2018 SOT conference with Ellegaard Minipigs comparing toxic response of mouse and minipig to novel anticancer drug. Ellegaard provides Göttingen Minipigs used in toxicology studies.
- Marshall BioResourcesminorCollaborative presentation at 2018 SOT conference with Marshall BioResources alongside Ellegaard Minipigs on preclinical toxicology model comparison.
- PointCrosscorePartnership for SEND ASSURE service providing turnkey validation of SEND datasets against regulatory requirements. PointCross eDataValidator is used alongside Pinnacle21 validation to ensure FDA Technical Conformance Guide compliance and Technical Rejection Criteria avoidance.
Scale indicators5 records
Recent moves6 records
Expansion highlights4 records
Sequani competitors and assessment
Company assessmentDirect peers
- Charles River Laboratories: Largest global non-clinical CRO offering a broad portfolio of toxicology, reproductive toxicology, juvenile toxicology, and pathology services to pharma and agrochemical sponsors. Directly comparable to Sequani across most service lines but with materially greater scale, geographic reach, and integrated discovery-to-clinical offerings.
- Labcorp Drug Development (Fortrea): Major non-clinical CRO providing GLP toxicology, safety assessment, and bioanalysis for pharmaceutical and chemical clients. Overlaps Sequani's drug development, REACH, and SEND-related service portfolio with significantly larger capacity and global footprint.
- Inotiv (formerly Envigo): Preclinical CRO with strong toxicology, reproductive toxicology, and research-models capabilities serving pharma and crop protection sponsors. Direct overlap with Sequani on rodent/non-rodent toxicology and reproduction studies.
- Smithers (Smithers Avanza / Viscient): Preclinical CRO with non-clinical toxicology, SEND, and agrochemical regulatory testing services. Direct overlap with Sequani on GLP toxicology, SEND data services, and crop protection safety studies.
- CiToxLAB (now part of Charles River): Former independent European non-clinical CRO with strong general toxicology, reproduction, and inhalation toxicology capabilities; now part of Charles River but historically a direct peer to Sequani on European pharma and agrochemical safety work.
Broad incumbents
- WuXi AppTec: Global CRO/CDMO with non-clinical safety assessment, bioanalysis, and SEND capabilities across pharma and agrochemical clients. Comparable service lines to Sequani but operating at significantly larger scale with broad geographic presence.
- Eurofins Scientific: International testing laboratory group with extensive agrochemical, REACH, and pharmaceutical safety testing services. Overlaps Sequani on chemical safety, REACH, and crop protection toxicology testing through its agrochemical and pharma testing divisions.
- SGS: Global testing, inspection and certification company with REACH and crop protection regulatory testing services. Comparable to Sequani's chemical safety and crop protection divisions, though as part of a much broader TIC portfolio.
Emerging players
- Pharmaron: Integrated CRO/CDMO offering non-clinical toxicology, DMPK, bioanalysis, and SEND services for pharma and agrochemical clients. Comparable to Sequani's toxicology and bioanalysis capabilities but with broader integrated discovery services.
- Bionova Scientific: Preclinical CRO providing toxicology, bioanalysis, and SEND data services for biopharma sponsors. Overlaps Sequani on SEND ASSURE / regulatory data packages and GLP toxicology for smaller biotech clients.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
Sequani social profiles
Digital presenceSequani financial estimates
Financial estimateRevenue estimate
Valuation estimate
Sequani leadership team
Management profileNumber of profiles
Profiles2 records
Sequani funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Sequani M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Sequani
What does Sequani do?
Sequani is a contract research organization (CRO) providing non-clinical safety assessment services to pharmaceutical, crop protection, and chemical companies. Services span toxicology studies (general, genetic, reproduction, juvenile, carcinogenicity), bioanalysis, formulation sciences, pathology, clinical pathology, toxicokinetics/pharmacokinetics, biomarkers, microsampling, and SEND regulatory data compliance, all delivered under GLP with OECD, EPA, and JMAFF guideline adherence from a custom-designed facility with co-located laboratory and vivarium space.
Is Sequani a public or private company?
Sequani is a private company. It is classified as unknown and is currently operating.
When was Sequani founded?
Sequani was founded in 1982. It employs 51 to 100 people.
Where is Sequani based?
Sequani is headquartered in Ledbury, United Kingdom, in the Europe region.
How does Sequani make money?
One revenue line is on record: contract Research Services.
Who are Sequani's main competitors?
Direct peers on record are Charles River Laboratories, Labcorp Drug Development (Fortrea), Inotiv (formerly Envigo), Smithers (Smithers Avanza / Viscient) and CiToxLAB (now part of Charles River). Broad incumbents are WuXi AppTec, Eurofins Scientific and SGS. Emerging players are Pharmaron and Bionova Scientific.
Does Sequani have an API?
No public API is recorded for Sequani.
What industry is Sequani in?
Sequani's product category is Contract Research Organization (CRO) - Non-Clinical Toxicology. Its primary akta.pro industry code is HLAGAAAC, Toxicology & Safety Assessment CROs (GLP), with a secondary code of HLAGAKAK, Laboratory Quality & GLP/GCLP Compliance. Its NAICS code is 541380 and its SIC code is 8731.