AdvantaPure

What AdvantaPure does

AdvantaPure is the high-purity products division of NewAge Industries, Inc., a privately held, 100% employee-owned (ESOP) manufacturer established in 2000 and headquartered in Southampton, Pennsylvania, with a heritage dating back to 1954 through its parent. The company designs and manufactures platinum-cured silicone tubing (AdvantaSil), biopharmaceutical-grade thermoplastic elastomer tubing (AdvantaFlex), sustainable TPE tubing (EcoFlex), and custom single-use assemblies, complemented by PUPSIT integrity-testing assemblies, Final Fill assemblies, BioClosures container closure systems, molded manifolds, and the patented AdvantaPass aseptic transfer and Verigenics RFID (U.S. Patent 8,519,846) product lines. Manufacturing is vertically integrated across ISO Class 7 cleanrooms in the USA (Southampton and Warrington, PA) and the Netherlands (Coevorden, opened 2023), supported by in-house R&D, analytical, test, and pilot laboratories and an inventory of more than 100 prequalified components sourced from over 20 manufacturers.

The company sells primarily to biopharmaceutical and pharmaceutical manufacturers, with secondary reach into life science research, addressing contamination control, EU GMP Annex 1 alignment, sterility assurance, and validation documentation requirements. Revenue is generated through unit-priced hardware sales (tubing coils, assemblies, bottles, fittings, RFID tags) via a global network of more than 40 authorized distributors across North America, South America, Europe, Asia, Middle East, Africa, and the South Pacific, supplemented by direct sales for custom assemblies and large accounts; sales offices are operated in Hong Kong (2022) and Sao Paulo, Brazil. The pricing model is quote-based, not publicly disclosed, with reported product availability above 95%. Recent strategic emphasis has been on sustainability-led product innovation (EcoFlex, EcoVadis Platinum recognition in 2024, 1+ MW of solar generation, Zero Waste-to-Landfill commitment) and on broadening the primary-container portfolio (PETG Square Media Bottles, launched April 2026).

The business is led by CEO Mary Marcus of parent NewAge Industries following Ken Baker's 2026 retirement, with a board including former Deloitte, Avantor, and VWR executives, and a management team that has added senior commercial (Tim Shannon, formerly DSM Biomedical) and operational (Richard Chomik, formerly ALOE Group COO) leadership in 2024-2025.

Name

AdvantaPure

Legal name

NewAge Industries, Inc.

Website

https://advantapure.com

Company type

Private

Founded year

2000

Operating status

Operating

Headcount range

101–250 employees

Short description

AdvantaPure is the high-purity products division of NewAge Industries, manufacturing platinum-cured silicone and TPE tubing, single-use assemblies, BioClosures, and PETG bottles for biopharmaceutical and pharmaceutical manufacturers worldwide.

Ownership category

akta.pro rank

Product category

Biopharmaceutical Fluid Handling Components

NAICS

Surgical Appliance and Supplies Manufacturing (339113)

SIC

Plastics Products, Nec (3089)

akta.pro primary industry

Sterilization Consumables & Packaging (Wraps, Pouches, Indicators, Trays/Containers) (HLAHANAC)

akta.pro secondary industries

Aseptic Processing, Fill-Finish & Sterile Manufacturing Tech (isolators, lyophilization interfaces) (HLAAAJAG), Sterile & Aseptic Medical Packaging (Pouches, Wraps, Sterile Barriers) (IMALAIAB), Medical & Pharmaceutical Thermoformed Packaging (IMANAHAB), Lab Safety, PPE & Contamination Control (Hoods, Biosafety Cabinets, Clean Air) (HLAGAIAK)

Keywords

• High purity tubing
• Silicone hose manufacturing
• Single use assemblies
• Biopharmaceutical fluid handling
• Sterile tubing components

Headquarters

HQ city

Southampton

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Supply Chain, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Tubing and Hose Products: Sale of high-purity tubing and hose products including AdvantaSil platinum-cured silicone, AdvantaFlex TPE, and EcoFlex sustainable tubing. Products sold per unit (coils, pieces) with pricing based on size and material.
2. Custom Single-Use Assemblies: Custom-manufactured single-use assemblies combining tubing, connectors, filters, sensors, bottles, and other components. Assembled and packaged in ISO Class 7 clean rooms with validated sterility.
3. Molded Components and Products: Precision injection molded components including manifolds, BioClosure systems, stoppers, and overmolded connections for single-use biopharmaceutical applications.
4. PETG Bottles and Containers: Sale of PETG square media bottles in sizes from 125mL to 2000mL for storage and transfer of critical fluids in pharmaceutical and biopharmaceutical applications.
5. Clamps, Fittings, and Accessories: Component sales including Oetiker clamps, crimp fittings, Thermobarb fittings, hose holders, and other fluid transfer accessories.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

AdvantaPure manufactures high-purity platinum-cured silicone and TPE tubing, hose, PETG media bottles, molded connectors and BioClosures, and custom single-use fluid transfer assemblies for biopharmaceutical and pharmaceutical manufacturers. Products are assembled in ISO Class 7 cleanrooms under a validated gamma sterility program and distributed globally for applications including media preparation, buffer storage, aseptic filling, cell culture, fill-finish, and PUPSIT integrity testing.

Product overview

AdvantaPure is a manufacturer of high-purity tubing, hose, and single-use assemblies for the biopharmaceutical and pharmaceutical industries. The product portfolio centers on two main tubing families: the AdvantaSil® platinum-cured silicone line (including APST, APLT, APHP, APSPG pump tubing, APSH braid-reinforced hoses, and APSW wire-reinforced hoses) and the AdvantaFlex®/EcoFlex® biopharmaceutical TPE tubing lines. These are complemented by single-use assemblies (custom-built with validated sterility programs), PUPSIT integrity testing assemblies, Final Fill assemblies, PETG bottles, BioClosures® container closure systems, AdvantaPass® cleanroom pass-through technology, molded manifolds, hose holders, RFID tracking solutions (Verigenics/GammaTag), labeling systems (AdvantaLabel, Doculink), and clamps & fittings. The company operates manufacturing facilities in the USA (Southampton and Warrington, PA) and the Netherlands (Coevorden), with global sales offices in Hong Kong and Brazil.

Differentiator

Problem solved

Functional benefit

Brands

• AdvantaSil: Platinum-cured silicone tubing and hose product line
• AdvantaFlex
• EcoFlex
• BioClosure
• AdvantaPass
• Verigenics
• AdvantaLabel
• AdvantaBio

Products and services

• AdvantaSil Platinum-Cured Silicone Tubing & Hose Exclusive line of platinum-cured silicone tubing and hose for biopharmaceutical and pharmaceutical fluid transfer, including unreinforced tubing, pump tubing, braid-reinforced hoses, and wire-reinforced suction hoses. Designed for contamination-sensitive processes and validated to USP Class VI and ISO standards.
• AdvantaFlex Biopharmaceutical TPE Tubing Flexible, sterilizable, weldable, and heat-sealable biopharmaceutical-grade thermoplastic elastomer tubing manufactured without silicone oils. Maintains physical properties and translucence following sterilization, and is weldable to similar TPE tubing assemblies for single-use systems.
• EcoFlex Sustainable TPE Tubing Sustainable bio-based thermoplastic elastomer tubing for single-use biopharmaceutical and pharmaceutical applications, reducing product carbon footprint by approximately 15–25% versus fossil-based TPE without compromising single-use performance.
• APFOS Stainless Steel Overbraided PTFE Hose High-purity process hose with white PTFE liner, smooth or convoluted interior, and optional silicone jacketing for demanding chemical transfer applications in pharmaceutical and bioprocessing environments.
• Single-Use Assemblies Custom-manufactured single-use assemblies using AdvantaSil platinum-cured silicone or AdvantaFlex TPE tubing, designed and built in ISO Class 7 clean rooms with validated sterility programs. Assemblies combine tubing, connectors, filters, sensors, bottles, and other prequalified components with no minimum order quantity.
• PUPSIT Assemblies Pre-Use Post-Sterilization Integrity Testing single-use assemblies designed to meet EU GMP Annex 1 requirements, supporting manual, semi-automated, or fully automated filter integrity testing configurations in sterile fill-finish operations.
• Final Fill/Bulk Filling Assemblies Custom bioprocess filling assemblies engineered for final fill-finish and bulk filling operations with precision overmolding and molded manifold capabilities for aseptic filling of sterile injectable products.
• BioClosures Container Closure Systems Precision-molded single-use container closure systems for secure, sterile fluid handling in biopharmaceutical processes. Compatible with bottles, flasks, and carboys with configurable tubing and vent filters.
• PETG Square Media Bottles High-clarity PETG square media bottles for secure storage and transfer of critical fluids in pharmaceutical and biopharmaceutical applications, available in 125, 250, 500, 1000, and 2000 mL sizes with gamma stability up to 50 kGy and freeze/thaw capability to -85°C. Tested to USP <665> Extractables/Leachables and USP <661.2>.
• Molded Manifolds and Components Single-use molded components produced via precision injection molding and overmolding, including Y connectors, T connectors, cross connectors, reducer connectors, and Tri-Clamp connectors in silicone. Reduces assembly time from hours to minutes and eliminates barbs, fittings, and clamps.
• AdvantaPass Clean Room Pass-Through Technology Patented wall or bulkhead pass-through system for aseptic fluid transfer between cleanrooms and processing areas, available in 4-inch and 6-inch portal sizes with optional purge ports. Eliminates hard piping cleaning and validation steps.
• Hose Holders Hose management devices that keep hoses off floors, eliminate contamination and tangling, and reduce tripping hazards in bioprocessing and pharmaceutical manufacturing environments. Made of HDPE in orange and yellow.
• Verigenics RFID Tracking Solutions (GammaTag) Read/write RFID technology (GammaTag) for identifying and tracking critical process components including single-use systems, bags, manifolds, filters, and tubing through gamma radiation sterilization. Covered by U.S. Patent 8,519,846 and RoHS-compliant.
• AdvantaLabel Hose Labeling System Sealed label applied directly onto tube or hose that withstands chemical cleaning and steam sterilization without degrading, made from permanently vulcanized silicone with optional color striping for hose identification in biopharma and pharmaceutical applications.
• Doculink Manifold Assembly Identification System Single-use manifold tracking system with label permanently molded into silicone connection for document retrieval and part tracking. Handles CIP, SIP, gamma irradiation, and autoclave processes.
• Clamps & Fittings Premium sanitary clamps and fittings including Oetiker Clamps, Crimp Fittings, and Thermobarb Fittings for bioprocess and pharmaceutical fluid transfer assembly construction.

Quantifiable outcome

• 25% reduction in product carbon footprint with EcoFlex sustainable tubing
• +3 more outcomes

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

Ten partnerships are on record, tiered regional and core.

• Carolina Components GroupregionalChannel Partner/ Reseller/ Distributor · 24 February 2026Regional distributor partnership for the EcoFlex sustainable tubing launch. Formal industry introduction conducted at ISPE Carolina-South Atlantic Chapter event on February 25, 2026 in Raleigh, NC.
• Fisher Scientific CompanycoreChannel Partner/ Reseller/ DistributorMajor scientific distributor providing AdvantaPure products to laboratory and research customers across North America (primarily Canada).
• High Purity New EnglandcoreChannel Partner/ Reseller/ DistributorRegional distributor specializing in high purity products serving the New England biopharmaceutical market.
• Qosina Corp.coreChannel Partner/ Reseller/ DistributorDistributor of single-use components and process equipment for medical device and pharmaceutical manufacturers.
• ESI Technologies (Ireland)regionalChannel Partner/ Reseller/ DistributorRegional distributor serving the Irish and European market from North Esk Business Park, Dunkettle, Co. Cork.
• Bioprocess Systems Alliance (BPSA)coreStrategic or Co-development PartnerActive member of BPSA, participating in BPSA Summit 2026. BPSA is the industry association for bioprocess systems technology.
• BiophorumcoreStrategic or Co-development PartnerActive member of Biophorum, collaborating on industry best practices and development for biopharmaceutical manufacturing.
• ISPE (International Society for Pharmaceutical Engineering)coreStrategic or Co-development PartnerActive member and participant in ISPE events including regional chapter events (ISPE Carolina-South Atlantic Chapter) for product launches and industry engagement.
• PDA (Parenteral Drug Association)coreStrategic or Co-development PartnerActive member supporting pharmaceutical engineering and manufacturing excellence through industry association.
• ISO (International Organization for Standardization)coreStrategic or Co-development PartnerOperations certified and aligned with ISO standards including ISO 9001:2015 quality management.

Scale indicators9 records

Recent moves9 records

Expansion highlights6 records

Broad incumbents

• Sartorius Stedim Biotech: Largest pure-play bioprocess supplier, offering integrated single-use systems (Flexsafe, Ambr), tubing, filters, and bioreactors. Directly competes with AdvantaPure in single-use assemblies for biopharma fluid handling while bundling broader upstream and downstream offerings.
• Cytiva (Danaher): Major supplier of bioprocessing single-use solutions (Xcellerex, ReadyToProcess, Allegro) including tubing, manifolds, and assemblies. A primary direct competitor serving overlapping pharma/biopharma accounts with broader portfolio depth.
• Thermo Fisher Scientific: Through its BioProduction and Chemicals segments (e.g., Nalgene, Nunc), Thermo Fisher supplies high-purity fluid transfer, single-use containers, and bioprocessing consumables competing with AdvantaPure's tubing/assembly and PETG bottle lines.
• Avantor: Global supplier of biopharma production materials, single-use assemblies, and fluid handling solutions (J.T.Baker, VWR legacy). Competes with AdvantaPure in biopharma consumables, and AdvantaPure board member Mark Thornton previously held leadership roles at Avantor.

Direct peers

• Saint-Gobain Life Sciences: Manufactures C-Flex, Sani-Tech, PharMed, and Tygon high-purity tubing and single-use assemblies for pharma and biopharma, a direct comparable for AdvantaSil and AdvantaFlex lines with similar regulatory documentation and customization capabilities.
• Trelleborg Healthcare & Medical: Produces silicone and TPE tubing, BioPharma single-use solutions, and molded components serving medical device and biopharmaceutical manufacturers - overlapping product portfolio and customer base with AdvantaPure.
• Watson-Marlow Fluid Technology: Specializes in peristaltic pumps and platinum-cured silicone/TPE tubing (PureWeld, BioPure) for bioprocessing. Maurice LeCompte (VP Business Development at AdvantaPure) previously worked at Watson-Marlow, indicating a strong adjacency in product, application, and customer base.
• Parker Hannifin (domnick hunter / Life Sciences): Provides high-purity fluid handling and single-use bioprocessing solutions (domnick hunter / SciLog / Parker) including filtration, sensors, and aseptic transfer technology - overlapping with AdvantaPure's assemblies, AdvantaPass-style aseptic transfer, and BioClosure portfolio.
• Qosina: Distributor and assembler of single-use components and bioprocess fittings used in pharma/medical device manufacturing. Lists AdvantaPure as a partner today, but mirrors the single-use assembly, clamps, and fittings category from an OEM/distributor dual perspective.

Regional players

• Cole-Parmer (Antylia Scientific): Distributes Masterflex platinum-cured silicone tubing and single-use bioprocess fluid handling components in lab and production settings, overlapping in product type and serving similar end-users, with broader North American laboratory distribution strength.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/user/AdvantaPure
• LinkedInlinkedin.com/company/advantapure
• Xx.com/advantapure
• Facebookfacebook.com/AdvantaPure-High-Purity-Tubing-Hose-Single-Use-Systems-1808704052684627

Compliance11 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Subsidiaries3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about AdvantaPure