What ProteoGenex does

ProteoGenex is a privately held US biospecimen and clinical-information provider founded in 2003 in Los Angeles (now headquartered in Inglewood, CA). The company operates a centralized biorepository of over 450,000 unique specimens — and more than 800,000 collected cumulatively over 20+ years — spanning fresh frozen tissues, FFPE tissues, blood products, biofluids, bone marrow/PBMCs, RNA/DNA, FDA Tissue Panels, matched tumor/normal pairs, and single-cell suspensions, with coverage across 450+ disease indications in Oncology, Dermatology, Neurology, Immunology, Infectious Diseases, Autoimmune, and Metabolic Disorders. Every specimen is accompanied by extensive clinical and pathological metadata including diagnosis, grade, TNM staging, biomarker status, treatment history, and up to five years of follow-up, with quality enforced through RIN≥7 RNA integrity checks, H&E pathology review by certified pathologists, and ≥60% tumor content thresholds.

The company's revenue model mixes transactional catalog sales of pre-collected specimens with higher-value custom services. Inventory sales operate on per-specimen, pay-as-you-go pricing across a range of tissue, blood, biofluid, and nucleic-acid formats. Custom Collections — a multi-year professional services offering — covers prospective specimen procurement with project management, custom protocol and Informed Consent Form development, site monitoring, and longitudinal study support. Tissue Microarray (TMA) construction (up to 300 cores per block in 0.6mm, 1mm, or 2mm sizes) and Human Single-Cell Suspension services extend the custom-service line into biomarker-screening and single-cell genomics workflows. A wholly-owned sister company, DxBiosamples, extends US tissue collection capacity.

ProteoGenex serves two primary B2B segments — pharmaceutical and biotechnology companies (drug discovery, companion diagnostics, clinical trial support, biomarker validation) and academic/government/non-profit research institutions (cancer research, proteomics, genomics, diagnostic assay development) — through direct enterprise sales organized by customer type, with dedicated phone/email channels for industry versus academia. Marketing relies on regular scientific conference presence (AACR, Molecular Medicine Tri-Conference, World Pharma Week), the company's publication footprint across hundreds of peer-reviewed papers, and a specimen-request-driven website funnel. All operations are conducted under IRB/IEC, HIPAA, GCP, and ICH compliance with WHO-aligned ethical standards.

Name

ProteoGenex

Legal name

ProteoGenex, Inc.

Website

https://proteogenex.com

Company type

Private

Founded year

2003

Operating status

Operating

Headcount range

11–50 employees

Short description

ProteoGenex is a privately held US biospecimen provider (founded 2003) operating a 450,000+ specimen biorepository across 450+ disease indications, serving pharmaceutical, biotechnology, and academic research customers with catalog specimens, custom prospective collections, tissue microarrays, and single-cell suspensions under full IRB/HIPAA compliance.

Ownership category

akta.pro rank

Product category

Biobanking & Human Biospecimen Supply

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Sample Logistics, Biorepository & IVD Kit Management (Trial Support) (HLAGAEAI)

Keywords

• Human biospecimen supply
• Tissue specimen procurement
• Biorepository services
• Custom biospecimen collection
• Tissue microarray construction

Headquarters

HQ city

Inglewood

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Supply Chain, Infrastructure, Marketing or Sales, Technology or R&D

Revenue model

1. Biospecimen Sales (Inventory): Direct sales of pre-collected human biological specimens from existing inventory including fresh frozen tissues, FFPE tissues, blood products, biofluids, and RNA/DNA. One-time transaction model with per-specimen pricing.
2. Custom Collection Services: Prospective specimen collection services tailored to specific research requirements. Includes project management, site monitoring, protocol development, and custom Informed Consent Form development. Long-term study support with diagnosis through treatment and beyond.
3. Tissue Microarray (TMA) Services: Custom-built TMA blocks for target expression and biomarker analysis. Core sizes 0.6mm, 1mm, 2mm; up to 300 cores per block. Slides cut and prepared from TMA blocks with H&E images provided.
4. Single-Cell Suspension Services: Isolation of primary cells from fresh tissues using collagenase digestion. Approximately 1x10^7 cells per tissue specimen, stored in vapor phase liquid nitrogen.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels3 records

Core offering

ProteoGenex provides ethically sourced human biological specimens—fresh frozen tissues, FFPE tissues, FDA Tissue Panels, blood products (whole blood, serum, plasma), viable BMMCs/PBMCs, biofluids, and RNA/DNA—from a centralized biorepository of 450,000+ unique specimens. The company also delivers custom specimen collection services, custom-design tissue microarray (TMA) blocks, and human single-cell suspensions, all accompanied by extensive clinical and pathological data and verified through a stringent quality control program.

Product overview

ProteoGenex is an established provider of human biological specimens and clinical information, operating a centralized biorepository with over 450,000 specimens. The portfolio consists of the core Biorepository product offering various specimen types (fresh frozen tissues, FFPE tissues, blood products, biofluids, RNA/DNA, BM/PBMCs), complemented by Custom Services (Custom Collections, Tissue Microarrays, Human Single-Cell Suspensions) and a Quality Control Program. The Biorepository serves as the foundational inventory, while Custom Services enable prospective collection and custom-designed tissue-based research solutions. All products are supported by extensive pathology information and patient clinical history documentation.

Differentiator

Problem solved

Functional benefit

Products and services

• Biorepository (centralized specimen catalog) Centralized inventory of 450,000+ human clinical specimens including frozen and FFPE tissues, blood products, biofluids, bone marrow, PBMCs, and RNA/DNA, covering disease targets in Oncology, Hematology, Neurology, Immunology, Infectious Diseases, and other clinical areas. Sold to pharmaceutical, biotechnology, and academic researchers.
• Fresh Frozen Tissues Snap-frozen human tissue specimens collected under IRB approval by certified medical pathologists, stored in vapor-phase liquid nitrogen at -190°C, with standard sample weight 0.5-1.0 gram and RNA Integrity Number (RIN) of 7 or higher. Available for oncology, neurology, immunology, and other research use.
• Formalin-Fixed Paraffin-Embedded (FFPE) Tissues FFPE tissue specimens fixed in 10% Neutral-Buffered Formalin within 30-60 minutes of surgery and embedded in IHC-grade paraffin, stored at room temperature with detailed clinical and pathological information. Designed for IHC, ISH, and molecular pathology research applications.
• FDA Tissue Panel Full FDA Panel of high-quality normal tissues for antibody cross-reactivity studies, available in fresh frozen and FFPE formats with clinical data including age, gender, ethnicity, and collection information. Targeted at antibody developers and diagnostic assay developers.
• Whole Blood, Serum, and Plasma Blood products collected from normal and diseased donors: whole blood (up to 40 mL per donor), serum (~10-12 mL per draw), and plasma (~12-15 mL per draw), processed within 4 hours of collection and stored at -80°C. Used for biomarker, serology, and clinical research.
• Bone Marrow Mononuclear Cells (BMMCs) & Peripheral Blood Mononuclear Cells (PBMCs) Viable bone marrow mononuclear cells and peripheral blood mononuclear cells with at least 95% viability at freezing, stored and shipped in vapor-phase liquid nitrogen at -190°C. Designed for immunology, cell-therapy, and immune-monitoring research.
• Biofluids Biofluid specimens including urine, stool, ascites fluid, saliva, sputum, synovial fluid, and cerebrospinal fluid (CSF) collected from normal and diseased donors under IRB approval. Used for metabolomics, microbiome, and biomarker research.
• RNA & DNA Genetic derivatives (RNA and DNA) extracted from human tissues and biological fluids, with RNA specimens analyzed for integrity using the Agilent 2100 Bioanalyzer and stored in vapor-phase liquid nitrogen. Sold for genomics, transcriptomics, and molecular biology research.
• Custom Collections (Prospective Specimen Collection Services) Custom specimen collection services tailored to specific research requirements, including project management, custom protocol development, clinical site training, custom Informed Consent Form development, and longitudinal study support from diagnosis through treatment and beyond. Sold to pharmaceutical/biotech programs and academic investigators needing prospective or matched-donor collections.
• Tissue Microarray (TMA) Blocks Custom-designed TMAs for target expression and biomarker analysis using carefully selected donors' FFPE tissues, with core sizes of 0.6 mm, 1 mm, and 2 mm and up to 300 cores per block (0.6 mm). Includes detailed tissue-core maps linking each core to clinical information, H&E images, and follow-up data where available. Sold to pharma, biotech, and academic researchers running high-throughput tissue studies.
• Human Single-Cell Suspensions Isolated primary human cells from fresh tissues (solid tumors and normal tissues) prepared via collagenase digestion, yielding approximately 1×10⁷ cells per tissue specimen, stored in vapor-phase liquid nitrogen. Designed for single-cell genomics, cell-therapy research, and downstream cellular assay applications.

Named customers1 record

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

One partnership is on record.

• DxBiosamplescoreStrategic or Co-development PartnerSister company providing tissue specimen collection services in the United States. ProteoGenex refers custom tissue collection requests to DxBiosamples, expanding their collective collection network and capabilities for prospective specimen procurement.

Scale indicators6 records

Recent moves5 records

Expansion highlights5 records

Direct peers

• Cureline: Human biospecimen CRO specializing in prospective collection of tissues, blood, and biofluids under IRB-approved protocols with detailed clinical data. Comparable to ProteoGenex's custom collections and longitudinal offerings, with similar disease-area breadth.
• Tissue Solutions: UK-based provider of ethically sourced human tissue and biofluid samples with global distribution to pharma and academic clients. Directly comparable on custom and catalog biospecimen procurement, though operating primarily from a European base.
• Discovery Life Sciences: Integrated biospecimen and bioservices provider offering tissue, blood, and cell products plus custom collections, flow cytometry, and molecular services. Overlaps heavily with ProteoGenex in biospecimen catalog and custom procurement, with broader downstream service capabilities.
• BioIVT: One of the largest global providers of human biospecimens, including fresh frozen tissues, FFPE, blood products, and biofluids for pharma and academic research. Directly competes with ProteoGenex on catalog inventory, custom collections, and disease-area coverage, but at significantly greater scale and multi-site footprint.
• BioChain Institute: Supplier of human tissue specimens, RNA/DNA derivatives, and protein products for research and diagnostic development. Overlaps with ProteoGenex's catalog offerings in FFPE tissues and nucleic acid derivatives for pharma and academic use.
• Indivumed: Provider of high-quality, clinically annotated human tissue samples and biofluids with a focus on oncology research. Competes with ProteoGenex on premium, annotated biospecimens and custom oncology collections.

Emerging players

• iSpecimen: Marketplace platform connecting researchers to a federated network of human biospecimen providers. Represents an alternative procurement model that could disintermediate traditional catalog providers like ProteoGenex by aggregating supply digitally.
• Capitainer: Provider of dried blood spot and volumetric sampling technologies used in biospecimen collection and biobanking. Adjacent rather than directly competitive, but relevant as an enabling technology provider in the broader human biospecimen ecosystem.

Broad incumbents

• ReproCELL: Life science company offering biospecimens (including fresh and frozen tissues), primary cells, and iPSC-derived products for drug discovery. Broader portfolio than ProteoGenex, but overlaps on tissue procurement and custom human biological samples.
• Asterand Bioscience (now part of BioIVT): Historically a direct peer in human tissue biospecimens, now absorbed into BioIVT's xPDC (Biospecimen) division. Referenced as a benchmark for the type of mid-sized competitor that has been consolidated into larger incumbents.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/proteogenex-inc-

Revenue estimate

Valuation estimate

Number of profiles

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about ProteoGenex