Reproductive Genetics Institute

What Reproductive Genetics Institute does

Reproductive Genetics Institute (RGI, formally Reproductive Genetic Innovations, LLC) is a Northbrook, Illinois-based specialty clinical genetics laboratory founded in 1989 by Dr. Yury Verlinsky. The company performs Preimplantation Genetic Testing (PGT) on embryo biopsies produced during IVF cycles, offering PGT-A (aneuploidy) using Next-Generation Sequencing with 98% accuracy on blastocyst biopsies, PGT-M (monogenic/single-gene defects) using PCR combined with proprietary DNA linked-marker analysis across a catalog of 850+ testable disorders, PGT-SR (structural rearrangements) down to 4-5 Mb resolution, and PGT-HLA matching for stem cell transplantation compatibility. RGI operates a referral-driven model serving approximately 200 IVF centers and clinics globally, augmented by direct-to-consumer patient and provider portals for genetic counseling, scheduling, and results.

The company monetizes laboratory testing as professional services revenue per cycle with no publicly disclosed pricing; ancillary revenue streams include embryology services (ICSI, blastocyst culture, biopsy, vitrification), andrology services (semen analysis and processing), and short- and long-term cryobank storage including international frozen specimen logistics. Free insurance consultations are offered to expand patient access. RGI is privately held with no disclosed institutional investors and appears to operate on a cash-flow positive basis given its 35-year history, though no revenue figures are public.

Leadership is concentrated among field-defining figures. Dr. Svetlana Rechitsky has served as President and Lab Director since 2010, succeeding founder Dr. Yury Verlinsky; the executive board includes former PGDIS and ASRM presidents and 100+ years of combined PGT experience. The company's regulatory footprint includes CAP accreditation, CLIA certification, and state laboratory permits in New York and Maryland. RGI claims multiple first-in-world achievements including the first PGT for a single gene disorder (1990), first PGT-HLA matching (1999), and first PGT for Prion disorder (2014), and reports facilitating the birth of more than 10,000 healthy babies across 42,000+ cumulative PGT cycles.

Name

Reproductive Genetics Institute

Legal name

Reproductive Genetic Innovations, LLC

Website

https://rgiscience.com

Company type

Private

Founded year

1989

Operating status

Operating

Headcount range

11–50 employees

Short description

Reproductive Genetic Innovations (RGI) is a Northbrook, Illinois-based genetic testing laboratory founded in 1989 that provides preimplantation genetic testing (PGT) for aneuploidy, monogenic disorders, structural rearrangements, and HLA matching via approximately 200 IVF clinic partners worldwide.

Ownership category

akta.pro rank

Product category

Reproductive Genetic Testing Services

NAICS

Research and Development in the Physical, Engineering, and Life Sciences (54171), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Medical Laboratories (8071)

akta.pro primary industry

Prenatal, Newborn & Reproductive Diagnostics (NIPT, IVF/PGT, newborn screening) (HLAAALAJ)

akta.pro secondary industry

Genetic, Cytogenetic & Prenatal Screening IVD (HLAHAAAI)

Keywords

• Preimplantation genetic testing
• Reproductive genetics lab
• IVF genetic services
• Embryology and andrology
• Cryobank storage services

Headquarters

HQ city

Northbrook

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. PGT Laboratory Testing Services: Preimplantation genetic testing services including PGT-A, PGT-M, PGT-SR, and PGT-HLA performed on embryo biopsy samples submitted from IVF cycles.
2. Cryobank Services: Short and long-term cryopreservation storage for oocytes, embryos, and semen samples. Services include receiving transferred frozen specimens from other facilities.
3. IVF and Embryology Services: Full spectrum of embryology services including oocyte/embryo culture, insemination (ICSI), blastocyst culture, embryo transfer, embryo and oocyte vitrification, embryo biopsies, semen analysis, and cryopreservation.
4. Andrology Services: Comprehensive semen analysis including sperm count, motility, morphology, viability assessment, special analysis on TESE/MESA samples, sperm processing for IVF, and cryopreservation.
5. Genetic Counseling Services: Pre-test genetic counseling consultations, case review, and interpretation of genetic results provided as part of PGT services.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels4 records

Core offering

Reproductive Genetics Institute (RGI) is a clinical genetics laboratory that performs preimplantation genetic testing (PGT) on embryo biopsy samples submitted from IVF cycles, including PGT-A for aneuploidy, PGT-M for monogenic/single gene disorders, PGT-SR for structural rearrangements, and PGT-HLA for HLA-matched stem cell donor identification. RGI also provides complementary embryology, andrology, cryobank, and genetic counseling services to fertility clinics, IVF centers, and patients.

Differentiator

Problem solved

Functional benefit

Products and services

• PGT-A (Preimplantation Genetic Testing for Aneuploidy) NGS-based test that determines whether an embryo contains the normal number of chromosomes prior to pregnancy, with 98% accuracy on blastocyst (Day 5/6) biopsy. Performed on embryo biopsy samples referred by fertility clinics during IVF cycles.
• PGT-M (Preimplantation Genetic Testing for Monogenic/Single Gene Defects) Customized PCR-based testing to identify single-gene disorders (autosomal dominant, recessive, X-linked, and de novo) using proprietary linked-marker DNA fingerprinting for accuracy. Designed for at-risk couples, with test setups for rare conditions not available at other labs.
• PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements) NGS-based test that detects structural chromosomal abnormalities from translocations, inversions, deletions, and duplications, including fragments as small as 4-5 Mb, combined with aneuploidy identification.
• PGT-HLA (Preimplantation HLA Matching) Test that identifies embryos HLA-compatible with a sibling needing bone marrow or cord blood transplant, using DNA fingerprinting of the affected child's HLA region with 8+ polymorphic markers.
• Embryology Services Full spectrum of embryology services including oocyte/embryo culture, insemination (ICSI), blastocyst culture, embryo transfer, embryo and oocyte vitrification, embryo biopsies, and semen analysis. Includes traveling embryology services for partner clinics.
• Andrology Services Comprehensive semen analysis including sperm count, motility, morphology, viability, TESE/MESA special analysis, sperm processing for IVF, and cryopreservation.
• Cryobank Services Short and long-term cryopreservation storage for oocytes, embryos, and semen samples, including receiving transferred frozen specimens from other facilities. Special pricing available for new long-term cryobank patients.
• Genetic Counseling Services Pre-test genetic counseling consultations, case review, and interpretation of genetic results provided as part of PGT services by board-certified genetic counselors.

Quantifiable outcome

• 98% accuracy in PGT testing
• +4 more outcomes

Named customers2 records

Segments4 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

AI capability4 records

Feature6 records

Partnerships

One partnership is on record.

• IVF Centers and Clinics WorldwidecoreChannel Partner/ Reseller/ DistributorRGI works with approximately 200 IVF centers and clinics worldwide, providing laboratory testing services for PGT and embryology support. These clinics refer patients to RGI for specialized genetic testing.

Scale indicators11 records

Recent moves7 records

Expansion highlights5 records

Broad incumbents

• Good Start Genetics (Invitae): Genetic testing platform (now part of Labcorp/Invitae) offering carrier screening and reproductive genetics panels that complement and partly overlap with RGI's PGT-M offering.
• Myriad Genetics: Established genetic diagnostics company with reproductive health offerings including carrier and prenatal screening. Adjacent competitor with much broader scale and a sales force that touches referring OB/GYNs.
• Sema4 (now part of GeneDx): Clinical genomics and reproductive health testing service with NGS-based offerings that overlap with parts of RGI's PGT and hereditary disease testing portfolio.
• Labcorp / Esoterix Reproductive Genetics: Large national reference laboratory network offering PGT and reproductive genetics through its Esoterix specialty lab. Broad incumbent competing on scale, logistics, and payer contracts rather than customization.

Direct peers

• CooperGenomics (CooperSurgical): Reproductive genetics laboratory specializing in PGT, NGS-based aneuploidy screening, and carrier screening for the IVF market. Directly comparable service portfolio and customer base to RGI.
• Igenomix: Global reproductive genetics laboratory offering PGT-A, PGT-M, PGT-SR, and complementary carrier/NIPT testing. Closest direct competitor to RGI in PGT services for IVF clinics and patients worldwide.
• Natera: Public genetic testing company with a dedicated reproductive health franchise (Spectrum PGT-A/PGT-M/PGT-SR) and broader women's health panels. Direct competitor in PGT lab services with greater commercial scale.
• Genomics Cooperative Laboratory: Reproductive genetics laboratory providing preimplantation and prenatal genetic testing services. Comparable niche player serving IVF clinics with overlapping test menus.

Emerging players

• Progenity: Molecular diagnostics company with reproductive and prenatal genetic testing products that compete for the same OB and fertility specialist mindshare as RGI.
• Genomic Prediction: NGS-based reproductive genetics laboratory focused on PGT-A and advanced embryo screening with polygenic risk scoring. Emerging player with overlapping technology but different clinical positioning.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/rgipgd
• Facebookfacebook.com/ReproductiveGeneticInnovations
• LinkedInlinkedin.com/company/reproductive-genetic-innovations

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Reproductive Genetics Institute