Limb Preservation Platform

What Limb Preservation Platform does

Limb Preservation Platform (LPP Research) is a privately held, freestanding clinical research and wound care center headquartered in Fresno, California, founded in 2014 by Dr. Shawn M. Cazzell, DPM. The company operates a single 8-treatment-room facility equipped with an on-site blood drawing and processing lab, refrigerated centrifuge, -80°C medical freezer, ECG machines, Doppler waveform/ABI/Nicolet diagnostic equipment, and X-ray capabilities. Its core offering is Phase I–IV clinical research trials focused on chronic difficult-to-heal lower extremity wounds — including diabetic foot ulcers, venous leg ulcers, peripheral arterial disease with neuroischemic ulcers, diabetic peripheral neuropathy, plantar fasciitis, onychomycosis, and bunions — alongside traditional wound care services delivered without hospital-based facility fees.

The business model is dual-track professional services. On the enterprise side, LPP contracts with pharmaceutical and medical device companies as a clinical trial site, leveraging GCP, NIH, and IATA-certified coordinators and Dr. Cazzell's standing as a Global Key Opinion Leader in diabetic lower limb/wound healing (40+ PI trials completed). On the patient side, the center recruits from the greater Fresno region (population exceeding 1,000,000) via local media (radio, TV), health fairs, community events, and referrals from local health centers, diabetes educators, and physicians' offices, offering free medical evaluation, treatment, supplies, and time/travel reimbursement for clinical trial participants — no medical insurance required.

The company remains founder-owned and controlled, with Dr. Cazzell as Founder/CMO and Vanessa Cazzell, PhD as President. It has no disclosed funding rounds, no external institutional investors, no patents, no awards, no partnerships, and no multi-site footprint. Operating scope is limited to the Central Valley of California. Revenue is generated through sponsor trial contracts and direct patient wound care fees, with no public pricing or revenue disclosure.

Name

Limb Preservation Platform

Legal name

LPP Research – Limb Preservation Platform, Inc.

Website

https://lppresearch.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

1–10 employees

Short description

Limb Preservation Platform is a Fresno-based clinical research and wound care center running Phase I–IV trials for chronic lower extremity wounds, serving pharmaceutical and medical device sponsors and recruiting patients from California's Central Valley.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Offices of Podiatrists (621391), Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Specialty Outpatient Facilities, Nec (8093)

akta.pro primary industry

Investigator & Site Training / GCP Support (HLAGACAF)

akta.pro secondary industries

Wound Care & Ulcer Management (HLAKACAN), Wound Care & Diabetic Foot Infection (HLAKAGAK)

Keywords

• Clinical research trials
• Wound care services
• Diabetic foot ulcer research
• Lower extremity wound management
• Phase I-IV clinical trials

Headquarters

HQ city

Fresno

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Clinical Research Trial Contracts: LPP conducts Phase I-IV clinical trials for pharmaceutical and medical device companies (sponsors), earning revenue through research contracts. They have experience with device and product trials ranging from topical administration to cell-based therapy for FDA submission.
2. Wound Care Patient Services: Traditional wound care services provided to patients without hospital-based facility fees, offering advanced wound management.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels3 records

Core offering

LPP Research is a freestanding wound care and clinical research center in Fresno, California that conducts Phase I-IV clinical trials for pharmaceutical and medical device sponsors focused on chronic difficult-to-heal wounds of the lower extremities (diabetic foot ulcers, venous leg ulcers, peripheral arterial disease, neuroischemic ulcers, peripheral neuropathy, plantar fasciitis, and onychomycosis). It also delivers traditional wound care services directly to patients without hospital-based facility fees, including free medical evaluation, treatment, supplies, and time/travel reimbursement for eligible clinical trial participants.

Product overview

Limb Preservation Platform (LPP) operates as a freestanding wound care and clinical research center dedicated to limb preservation and the advancement of lower extremity wound management. The company offers a unified offering composed of Phase I-IV clinical research trials focused on chronic non-healing wounds (diabetic foot ulcers, venous leg ulcers, peripheral arterial disease, peripheral neuropathy, plantar fasciitis, onychomycosis, Achilles tendonitis) alongside traditional wound care services delivered without hospital-based facility fees. The two service lines are closely integrated: the clinical research arm evaluates drugs and medical devices for wound healing while the wound care facility provides advanced wound management to patients and research participants. The company also conducts trial sponsorship coordination with pharmaceutical and medical device companies, featuring GCP/NIH/IATA-certified coordinators, on-site lab capabilities, and a -80°C medical freezer.

Differentiator

Problem solved

Functional benefit

Products and services

• Phase I-IV Clinical Research Trials Comprehensive Phase I through Phase IV clinical research trials focused on chronic difficult-to-heal wounds and therapeutic areas targeting the lower extremities, including diabetic foot ulcers, venous leg ulcers, peripheral arterial disease, peripheral neuropathy, plantar fasciitis, and onychomycosis. Trials are conducted for pharmaceutical and medical device sponsors at LPP's freestanding facility in Fresno, CA, with GCP/NIH/IATA-certified coordinators, on-site lab and diagnostic capabilities, and Central IRB submission support.
• Traditional Wound Care Services Freestanding wound care services offering advanced wound management without hospital-based facility fees, focused on lower extremity wound management and diabetic limb salvage for patients in California's Central Valley region.
• Diabetic Foot and Lower Leg Wound Care Specialized wound care services for diabetic foot ulcers, neuroischemic ulcers, heel pain, bunions, and peripheral neuropathy, including free medical evaluation, treatment, supplies, and time/travel reimbursement for eligible clinical trial participants.

Quantifiable outcome

• 50%+ of all wounds become infected; approximately 20% of infected lower extremity wounds lead to amputation - LPP works to prevent these outcomes

Segments8 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators9 records

Recent moves4 records

Expansion highlights4 records

Direct peers

• DM Clinical Research: Multi-site clinical research network specializing in diabetes and related therapeutic areas including diabetic foot ulcers — a closely comparable SMO focused on the same patient population and sponsor demand LPP serves.
• Accellacare (now part of a global site network): Specialty clinical research site network offering sponsors access to multi-site patient enrollment across Phase II-IV trials in multiple therapeutic areas — directly comparable to LPP's clinical trial recruitment model at a multi-site, scaled level.
• Meridien Research: Independent clinical research site network running multi-therapeutic Phase I-IV trials — closely comparable independent-site operator model to LPP, demonstrating the template for scaling beyond a single location.
• Woundtech: Specialized wound care clinical services provider focused on advanced wound management in non-hospital settings — directly comparable to LPP's outpatient wound care service line.
• Catawba Research: Independent clinical research services company supporting Phase I-IV trials across multiple therapeutic specialties including wound care — a comparable mid-size independent research services peer to LPP.

Broad incumbents

• IQVIA: Largest global CRO/SMO with broad therapeutic coverage and vast site network — the dominant scale competitor sponsors turn to for multi-site wound care and diabetic foot ulcer studies.
• Healogics: Largest US provider of wound care management services, operating hundreds of outpatient wound care centers and partnering with hospitals on limb preservation — directly comparable to LPP's traditional wound care service line at vastly larger scale.
• Medpace: Mid-size global CRO with a strong therapeutic focus including metabolic/endocrinology and wound-related indications — competes with LPP indirectly for sponsor trial placement decisions and exemplifies the scale LPP must compete against for high-value studies.
• Sarah Cannon Research Institute: Large US site management and clinical research network (part of HCA Healthcare) conducting Phase I-IV trials across multiple therapeutic areas — a different scale archetype of the SMO model LPP operates in.
• RestorixHealth: Multi-state operator of outpatient wound care centers and limb preservation programs across the US — overlapping wound care services focus with LPP at substantially larger geographic scale.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/limb-preservation-platform-inc

Compliance5 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Limb Preservation Platform