What Biotech Support Group does

Biotech Support Group LLC (BSG) is a privately held biotechnology research consumables company founded in 2004 by Swapan Roy, Ph.D. and headquartered in Monmouth Junction, New Jersey. The company develops and sells bead-based sample preparation products for proteomics, genomics, and metabolomics workflows, anchored on its proprietary NuGel silica surface chemistry platform and the NRicher Bead Chemistry Platform (introduced 2010). Core product lines include albumin/IgG depletion kits (AlbuVoid, AlbuSorb and PLUS variants), hemoglobin depletion kits (HemogloBind, HemoVoid), lipid clarification reagents (Cleanascite, Cleanascite LX), NRicher sub-proteome enrichment kits (Mx2, Apo, Ig, C, plus the forthcoming 4SP and 6 multi-bead formats), NuGel functionalized beads (Phenyl Boronic Acid, Poly-Aldehyde, Poly-Amine, Poly-Carboxy, BindPro), and ProCipitate DNA/RNA sample cleanup. The company was the first to commercialize proteomic enrichment and depletion products not based on immunoaffinity and claims over 100 peer-reviewed citations for Cleanascite alone with citations in Nature, Science, and Nature Protocols.

BSG sells consumables directly through its e-commerce website with worldwide phone/email support and a downloadable price list (specific prices not publicly displayed). Pricing is unit-based with trial kits for evaluation and standard catalog kits in 10–100+ prep sizes plus bulk bead formats; there is no recurring subscription, instrument rental, or service contract layer. Distribution is extended via a channel partnership with DPX Technologies (announced October 2021) to integrate depletion reagents with the pipette XTRaction automated workflow and via Pro Test Diagnostics AB (Sweden, 2019) for anti-doping applications. Revenue is generated entirely from one-time consumable purchases by proteomics researchers in academic, government, and commercial biopharma laboratories.

The customer base spans research institutions (Battelle National Laboratories), healthcare providers (Cleveland Clinic, Morton General Hospital), academic medical centers (Mount Sinai School of Medicine, Leiden University Medical Center, Rutgers Proteomics Center), government agencies (USDA, US Center for Disease Control, US Federal Drug Administration, US Army Medical Research Institute), and commercial diagnostics (Pro Test Diagnostics AB). The company also pursues co-development partnerships — notably with Leiden on the patent-pending Stroma Liquid Biopsy cancer biomarker panel and with Lawson Health Research Institute on COVID-19 protease monitoring — positioning itself as a bridge between proteomic biomarker discovery and clinical/diagnostic translation. BSG markets primarily through peer-reviewed citations and conference presence (ASMS, HUPO, ASBMB, MSACL) rather than traditional sales-led demand generation.

Name

Biotech Support Group

Legal name

Biotech Support Group LLC

Website

https://biotechsupportgroup.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

1–10 employees

Short description

Biotech Support Group, founded in 2004 and headquartered in Monmouth Junction, NJ, sells bead-based sample preparation consumables — albumin, hemoglobin, and lipid depletion kits plus the NRicher sub-proteome enrichment platform — built on its proprietary NuGel silica chemistry and serves proteomics researchers in academic, government, and biopharma laboratories worldwide.

Ownership category

akta.pro rank

Product category

Proteomic Sample Preparation Consumables

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industries

Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization) (HLAAAIAC), Impurity / Reference Standard Synthesis & Characterization (HLAGAHAG)

Keywords

• Proteomic sample preparation
• Bead-based depletion kits
• Albumin hemoglobin removal
• Lipid clarification reagents
• LC-MS sample prep

Headquarters

HQ city

Monmouth Junction

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Operations, Marketing or Sales, Personnel, Infrastructure

Revenue model

1. Proteomic Sample Prep Consumables: Sale of bead-based sample preparation kits and reagents including AlbuVoid, HemoVoid, Cleanascite, NRicher, and related products. Products are supplied as dry powders or kits including buffers, sold in catalog sizes ranging from trial kits to bulk formats. Consumable use model — no regeneration or specialized instruments required.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels6 records

Core offering

Biotech Support Group manufactures and sells bead-based sample preparation consumables (reagents, kits, and bulk bead products) used by proteomics, genomics, and metabolomics researchers to enrich low-abundance proteins, deplete high-abundance interfering proteins (albumin, IgG, hemoglobin), and clarify lipid-rich samples prior to LC-MS and other analytical workflows. Its products are built on two proprietary platforms — the NuGel passivated silica surface chemistry and the NRicher Bead Chemistry Platform — and are sold as catalog consumables in trial, standard prep, and bulk sizes.

Product overview

Biotech Support Group is a proteomic and genomic sample preparation company offering a portfolio of bead-based products centered on two proprietary technology platforms: the NuGel™ silica platform and the NRicher™ Bead Chemistry Platform. The core product lines include Albumin & IgG Removal Kits (AlbuSorb™, AlbuVoid™ and PLUS variants), Hemoglobin Removal Kits (HemogloBind™, HemoVoid™), Lipid Removal & Clarification products (Cleanascite™, Cleanascite™ LX), and NRicher™ enrichment kits for targeted proteomics. The NRicher™ platform provides family-specific enrichment for apolipoproteins, immunoglobulins, and complement cascade proteins, while NuGel™ serves as the foundational bead chemistry supporting all NRicher™-derived products. Additionally, ProCipitate™ provides DNA/RNA sample cleanup, and the company offers Stroma Liquid Biopsy™ as a biomarker panel offering. All products feature the 'BSG Advantage': consumable use not derived from biologicals, functional integrity, on-bead digestion capability, and species-agnostic chemistry.

Differentiator

Problem solved

Functional benefit

Products and services

• AlbuSorb™
• AlbuSorb™ PLUS Albumin and IgG depletion kit for serum or plasma that combines AlbuSorb chemistry with integrated Protein A technology to deplete >85% albumin and 85% IgG from 25 µL serum samples, intended for proteomics sample preparation.
• AlbuVoid™ Albumin depletion and low-abundance protein enrichment kit that selectively voids albumin while binding the low-abundance proteome on bead surfaces, achieving >95% albumin voiding in a <30 minute protocol. Supports on-bead digestion and is designed for proteomic sample preparation workflows.
• AlbuVoid™ LC-MS On-Bead Serum proteomics kit that selectively voids albumin and binds the low-abundance proteome before LC-MS use, with a seamless on-bead digestion workflow integrated into the kit format.
• AlbuVoid™ PLUS Albumin and IgG depletion kit for serum or plasma proteomics achieving >95% albumin removal and >90% IgG removal (70-80% total immunoglobulins) in a <1 hour protocol.
• AlbuTrial™ Kit Trial kit bundling 1 g AlbuSorb™ and 5 preps AlbuVoid™ to enable researchers to evaluate both albumin depletion workflows before scaling to standard kit sizes.
• AlbuTrial™ PLUS Kit Trial kit bundling 5 preps AlbuSorb™ PLUS and 5 preps AlbuVoid™ PLUS to enable researchers to evaluate combined albumin and IgG depletion workflows prior to scale-up.
• HemogloBind™ Hemoglobin depletion reagent for hemolyzed serum, plasma, RBC lysate, whole blood lysate, and tissue lysates, optimized for serum and plasma samples and removing 90-95% hemoglobin to improve biomarker visibility in proteomics workflows.
• HemogloBind™ Kit Complete hemoglobin depletion kit for hemolyzed serum and plasma, supplied with pre-measured reagents and buffers for a streamlined workflow.
• HemogloBind™ Blood Card Kit Hemoglobin depletion kit designed for dried blood spot processing, compatible with low-volume samples and suited to remote collection workflows.
• HemogloBind™ Trial Kit Trial kit bundling 5 mL HemogloBind™ and 5 preps NuGel-HemogloBind™ to support depletion-focused workflow validation.
• HemoVoid™ Proteomic enrichment product that selectively voids hemoglobin while capturing the majority of the remaining low-abundance proteome on bead for protein enrichment from erythrocytes (RBCs), delivering 20-fold PRDX6 enrichment versus alternative extraction methods.
• HemoVoid™ LC-MS On-Bead Direct LC-MS workflow kit in an on-bead digestion format for red blood cell proteomics, reducing processing steps and optimizing for downstream LC-MS analysis.
• HemoVoid™ Blood Card Kit Hemoglobin depletion kit for dried blood cards (DBS), enabling protein enrichment from dried blood spot samples with compatible downstream analysis.
• HemoVoid™ - Hemoglobin Variant Hemoglobin variant enrichment product designed to enrich hemoglobin variants from blood, supporting hemoglobin variant analysis and improved detection sensitivity.
• HemoTrial™ Kit Trial kit bundling 5 mL HemogloBind™, 5 preps NuGel-HemogloBind™, and 5 preps HemoVoid™ to enable comparison of multiple hemoglobin removal workflows.
• NuGel-HemogloBind™ Hemoglobin capture reagent for blood and hemolyzed serum with enhanced hemoglobin binding efficiency for complex sample matrices.
• Cleanascite™ Flagship lipid removal reagent and clarification product that selectively binds lipids, phospholipids, and phosphates while leaving proteins, antibodies, and nucleic acids intact, serving as a replacement for hazardous solvent extraction. Supports LC-MS, immunoassays, and cell response assays, with over 100 peer-reviewed citations.
• Cleanascite™ LX Lipid clarification product for lipemic serum and plasma samples, designed for visual and analytical sample cleanup with dilution-based turbidity removal.
• NRicher™ Mx2 General enrichment product for all biofluids and tissue lysates providing broad low-abundance proteome enrichment with a simple microfuge-compatible workflow.
• NRicher™ Apo Family-specific apolipoprotein enrichment kit targeting apolipoprotein-enriched fractions in serum and plasma workflows as part of the NRicher family-specific product line.
• NRicher™ Ig Family-specific immunoglobulin enrichment kit for enrichment of all isotypes and subclasses of immunoglobulins, introduced as part of the 2024 NRicher family-specific product line.
• NRicher™ C Family-specific complement cascade enrichment kit supporting innate immunity studies with targeted proteomics workflows, introduced as part of the 2024 NRicher family-specific product line.
• NuGel™ Phenyl Boronic Acid Glycoprotein enrichment bead system featuring phenyl boronic acid chemistry for selective glycoprotein capture, sold as a standalone NuGel bead reagent.
• NuGel™ Glycoprotein Enrichment PBA Kit Phenyl boronic acid-based glycoprotein enrichment kit built on NuGel™ beads for targeted glycoprotein isolation in proteomic sample preparation workflows.
• NuGel™ BindPro™ Protein removal and metabolite/analyte enrichment product from serum or plasma, designed for metabolomics sample preparation workflows using NuGel™ bead chemistry.
• NuGel™ Poly-Aldehyde Functionalized NuGel bead reagent with poly-aldehyde surface chemistry for targeted protein interactions and ligand immobilization in bioseparations workflows.
• NuGel™ Poly-Amine Functionalized NuGel bead reagent with poly-amine surface chemistry for enrichment workflows and ligand immobilization in bioseparations.
• NuGel™ Poly-Carboxy Functionalized NuGel bead reagent with poly-carboxy surface chemistry for protein binding applications and bioseparations.
• ProCipitate™ Sample cleanup and protein removal reagent for DNA/RNA preparation, originally invented by John Krupey, Ph.D. and used throughout the Human Genome Sequencing Project, now sold as a catalog reagent for genomic sample preparation.
• NuGel™ Platform Proprietary passivated silica platform that is the foundational chemistry behind every NRicher product, featuring a polymer coating that virtually eliminates non-specific protein binding sites and is stable across pH 2-10 using 50 µm porous (800 Å) silica. Sold as a bead product line with multiple functionalized variants.
• NRicher™ Platform Bead chemistry platform for proteome enrichment that enables sub-proteome fractionation without immuno-affinity, supporting simple consumable workflows without HPLC or specialized equipment. Includes broad, family-specific, and multi-bead formats for functional, chemical, and top-down proteomics alongside LC-MS workflows.
• Stroma Liquid Biopsy™ Patent-pending pan-cancer biomarker panel of dysregulation derived from blood, developed in collaboration with Leiden University Medical Center to correlate blood-borne biomarkers to tissue-derived tumor-stroma ratio scoring methods for liquid biopsy applications.

Quantifiable outcome

• Albumin depletion: 90-95% removal; AlbuVoid depletes albumin in flow-through >95%
• +7 more outcomes

Named customers12 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature5 records

Partnerships

Six partnerships are on record, tiered core and minor.

• DPX TechnologiescoreChannel Partner/ Reseller/ Distributor · 5 October 2021In-market partnership with DPX Technologies to integrate BSG's proprietary albumin, IgG, and HemogloBind depletion reagents with DPX's pipette XTRaction product line for high-throughput proteomic sample prep workflows. Extends BSG products into automated, pipette-based processing environments.
• Lawson Health Research InstitutecoreStrategic or Co-development Partner · 24 September 2021Collaborative research agreement to monitor protease inhibitor function during COVID-19 infections. Joint goal to develop proteomic methods that can monitor how the body's protease inhibitors are predisposed to suppress SARS-CoV-2 cell entry mechanisms, with potential for biomarkers to manage severe disease and guide therapeutic development.
• Leiden University Medical CentercoreStrategic or Co-development Partner · 20 May 2019Mutual research collaboration to correlate BSG's patent-pending Stroma Liquid Biopsy panel of blood-borne biomarkers to tissue-derived tumor-stroma ratio (TSR) scoring methods developed by LUMC. A 2022 publication in Cancers journal reported a gene signature ratio predicting survival in colon cancer based on this correlation.
• Pro Test Diagnostics AB (Umeå, Sweden)coreChannel Partner/ Reseller/ Distributor · 4 April 2019Supply agreement for HemoVoid product for blood doping detection applications. Pro Test Diagnostics AB distributes BSG's HemoVoid for forensic and anti-doping testing markets in Sweden.
• Rutgers Proteomics CentercoreStrategic or Co-development PartnerCollaboration on methods to improve LC-MS workflows for cost-effective data output. The New Jersey Catalyst Phase II Award ($40,000) for 'Evaluating the NRicher Bead Platform for Targeted LC-MS Quantification' is being conducted at The Rutgers Biological Mass Spectrometry Facility.
• ArrayBridge (St. Louis, MO)minorStrategic or Co-development PartnerCollaboration on new gel-based functional proteomic strategies and methods to sequence annotate the multi-functional proteome.

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Revvity (formerly PerkinElmer Life Sciences): Reagent and analytical solutions provider whose proteomics and translational-research offerings (including immunoassay and LC-MS sample-prep reagents) overlap BSG's clinical/translational customer base. Larger bundled enterprise contracts could pressure standalone vendors like BSG.
• Agilent Technologies: Mass-spectrometry and consumables supplier whose Affinity Removal Columns and proteomics sample-prep reagents target the same LC-MS workflow as BSG's NRicher and AlbuVoid kits, and whose integrated instrument-plus-reagents model puts competitive pressure on smaller consumable specialists.
• Cell Signaling Technology (CST): Antibody-based reagents and immunoaffinity depletion/enrichment kits (e.g., PTMScan, SeHTL) target the same proteomics customers as BSG's non-immunoaffinity NRicher and AlbuVoid products — representing the incumbent immunoaffinity paradigm BSG explicitly differentiates against.
• Thermo Fisher Scientific: Global life-sciences giant whose Pierce Albumin/IgG Depletion Kits and broader proteomics sample-prep portfolio directly overlap BSG's AlbuSorb, AlbuVoid and HemogloBind products. Comparably serves LC-MS proteomics customers but as part of a much broader reagents + instruments + services catalog, with bundled pricing and large field sales teams.
• Cytiva (Danaher Life Sciences): Provides bead-based and chromatography-based protein separation products (mixed-mode resins, affinity columns) used in protein purification workflows adjacent to BSG's bead depletion and enrichment kits. Competes for the same LC-MS and bioprocess sample-prep budget, but as part of a broader bioprocess platform.
• MilliporeSigma (Merck KGaA Life Science): Operates the legacy Sigma-Aldrich proteomics reagent catalog including albumin/IgG removal products, mixed-mode silica bead chemistries, and lipid-removal solvents that compete with BSG's NuGel and Cleanascite lines. Sells through an enormous direct and distributor footprint that dwarfs BSG's e-commerce storefront.

Emerging players

• Sengenics: Niche proteomics company offering protein-array-based biomarker discovery products for autoantibody and functional proteomics. Overlaps BSG's translational/biomarker customer base rather than its core bead-depletion workflow, making it an adjacent emerging player rather than a direct competitor.
• Olink Proteomics: Niche proteomics company built around targeted protein-biomarker platforms (Proximity Extension Assay). Competes for translational proteomics research budgets but solves a different problem (highly multiplexed readout) than BSG's bead-based sample-prep for LC-MS, making it more of a category adjacent than direct rival.

Direct peers

• Bio-Rad Laboratories: Direct competitor in proteomics sample prep, with Aurum Serum Protein Kits and related depletion/enrichment consumables used in similar LC-MS workflows to BSG's AlbuVoid and HemoVoid. Closely overlapping product format (kit-based, prep-count packaging) and target customer (academic and clinical proteomics labs).
• Promega Corporation: Privately held life-science reagent manufacturer with comparable size, founder/employee tenure, and proteomics/biomarker consumables portfolio (sample-prep kits, protease mixes, mass-spectrometry reagents) that overlaps BSG's catalog and customer base. Closest size- and business-model analog despite broader product breadth.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks7 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/biotech-support-group
• Xx.com/bioseparations
• Facebookfacebook.com/biotechsupportgroup

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Biotech Support Group