Genomics & Bioinformatics Core Facility

What Genomics & Bioinformatics Core Facility does

The Genomics & Bioinformatics Core Facility (GBCF) is an internal core facility of the University of Notre Dame, established in 2008-2009, that provides fee-for-service genomics experiments and bioinformatics analysis to the Notre Dame research community, Indiana Clinical and Translational Sciences Institute (CTSI) partner institutions, and external academic and industry clients. Located in B005 McCourtney Hall East, Notre Dame, Indiana, the facility combines wet-lab genomics capabilities with computational bioinformatics analysis under a single operational umbrella, with service requests processed through the iLab Core Facility Management System and pricing structured on a quote-based, usage-billed model.

GBCF's service portfolio spans next-generation DNA sequencing, single-cell sequencing, spatial transcriptomics, Sanger sequencing, and custom bioinformatics analysis, supported by an instrument base that includes the 10X Genomics Chromium Controller for high-throughput single-cell partitioning and molecular barcoding, the Illumina NextSeq 500 Sequencing System for whole-genome, exome, and transcriptome sequencing, the 10X Visium Spatial Gene Expression platform for spatial transcriptomics, and the ABI3730xl DNA Analyzer. The bioinformatics group performs data processing, standard and custom analytical workflows, and develops new computational tools, while the facility also delivers education and training through the REACT (Rapid Exposure to Advanced Computational Training) program and individual instruction. A COVID-19 Saliva Surveillance Testing operation added during the pandemic demonstrated operational scale at more than 1,100 tests per day with a one-day turnaround.

The facility generates revenue through a combination of fee-for-service charges to internal and external users, University of Notre Dame internal equipment grants, and pass-through funding from CTSI Pilot Funding (up to $10,000) and Postdoc Challenge (up to $5,000) programs. GBCF is a nonprofit unit within Notre Dame Research with no venture or private equity ownership, and operates as a cost-recovery service organization rather than a venture-backed business. Its go-to-market is direct sales to research PIs, with iLab serving as the bottom-of-funnel ordering platform and the Notre Dame Research website plus the REACT program serving as top-of-funnel awareness channels. Documented published collaborations span cancer biology, evolutionary and ecological genomics, vector-borne disease, climate change biology, and Daphnia genome assembly. The facility holds no patents and conducts no M&A.

Name

Genomics & Bioinformatics Core Facility

Legal name

University of Notre Dame

Website

https://genomics.nd.edu

Company type

Private

Founded year

2009

Operating status

Operating

Headcount range

1–10 employees

Short description

The Genomics & Bioinformatics Core Facility is the University of Notre Dame's internal core facility providing fee-for-service next-generation sequencing, single-cell profiling, spatial transcriptomics, and bioinformatics analysis to Notre Dame researchers, Indiana CTSI partner institutions, and external academic and industry clients.

Ownership category

akta.pro rank

Product category

Genomics Research Services

NAICS

Scientific Research and Development Services (5417), Research and Development in the Physical, Engineering, and Life Sciences (54171)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Bioinformatics, Multi-Omics Data Analysis & Interpretation Services (HLAGANAI)

Keywords

• Genomics sequencing services
• Bioinformatics analysis
• Next-generation sequencing
• Single-cell sequencing
• Spatial transcriptomics

Headquarters

HQ city

Notre Dame

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Infrastructure, Operations

Revenue model

1. Core Facility Services: Fee-for-service genomics and bioinformatics services provided to the Notre Dame research community, external academic institutions, and industry. Pricing is quote-based through an online request system.
2. Indiana CTSI Funding Programs: Postdoc Challenge grants ($5,000 awards for core facility services) and Core Pilot Funding (up to $10,000 for research use of core facilities) provide funding that flows to the facility for services

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

The Genomics & Bioinformatics Core Facility (GBCF) provides comprehensive genomics and bioinformatics services and support to academic and industry researchers. Offerings include next-generation DNA sequencing (Illumina NextSeq 500), single-cell sequencing (10X Genomics Chromium Controller), spatial transcriptomics (Visium), Sanger sequencing (ABI3730xl), PCR-based COVID-19 surveillance testing, custom bioinformatics analysis, and computational training through the REACT program. Services are delivered on a fee-for-service, quote-based pricing model.

Differentiator

Problem solved

Functional benefit

Products and services

• Genomics Sequencing Services Comprehensive genomics sequencing services including next-generation DNA sequencing, single-cell sequencing, whole genome/exome/transcriptome sequencing, and Sanger sequencing provided to academic researchers and external clients on a fee-for-service basis.
• Bioinformatics Analysis Bioinformatics analysis service offering data processing, custom bioinformatics tool development, and tailored computational analysis for genomic data generated by the facility or external sources.
• COVID-19 Saliva Surveillance Testing PCR-based saliva COVID-19 surveillance testing service operating at the Saliva Surveillance Lab in McCourtney Hall with robotic liquid handling for high-throughput sample processing.
• REACT Computational Training Program Short-term training program (Rapid Exposure to Advanced Computational Training) providing up to $1,300 per graduate student to attend computational workshops and training in bioinformatics tools and techniques.

Quantifiable outcome

• Over 1,100 COVID-19 surveillance tests processed per day with one-day turnaround during pandemic response
• +3 more outcomes

Named customers5 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• Mayo CliniccoreStrategic or Co-development Partner · 12 October 2022Notre Dame has partnered with Mayo Clinic on cancer research. GBCF provides genomics and bioinformatics support for collaborative cancer research projects.
• 10X GenomicscoreTechnology or Integration · 28 February 2019Partnership for Chromium Controller single-cell sequencing equipment and Visium Spatial Gene Expression technology. 10X Genomics provides equipment and reagent kits; GBCF provides processing, sequencing, and bioinformatics support. Cost share funding provided by Eck Institute of Global Health, Harper Cancer Research Institute, Boler-Parseghian Center for Rare and Neglected Diseases, and Center for Stem Cells and Regenerative Medicine.
• Indiana Clinical and Translational Sciences Institute (CTSI)coreStrategic or Co-development PartnerGBCF is an Indiana CTSI-approved Core Facility. CTSI provides funding programs including Postdoc Challenge grants ($5,000) and Core Pilot Funding (up to $10,000) that support researchers in using GBCF services. Services available to all CTSI partner institutions including Indiana University, IU School of Medicine, IUPUI, Purdue University, and IBRI.
• Harper Cancer Research InstitutecoreStrategic or Co-development PartnerGBCF is affiliated with the Harper Cancer Research Institute. Co-funded the acquisition of 10X Genomics Chromium Controller and Visium spatial transcriptomics technology. Collaborates on the REACT computational training program.
• Eck Institute for Global HealthcoreStrategic or Co-development PartnerGBCF is supported by the Eck Institute of Global Health with cost share funding for equipment acquisitions including the 10X Genomics Chromium Controller. Collaborates on REACT computational training program.
• Boler-Parseghian Center for Rare and Neglected DiseasescoreStrategic or Co-development PartnerCo-funded the acquisition of 10X Genomics Chromium Controller single-cell sequencing equipment. Funded cancer research through Catalyst Award supporting single-cell profiling studies.
• Center for Stem Cells and Regenerative MedicineminorStrategic or Co-development PartnerProvided cost share funding for the 10X Genomics Chromium Controller single-cell sequencing equipment acquisition.
• Environmental Change InitiativecoreStrategic or Co-development PartnerCo-funds the REACT (Rapid Exposure to Advanced Computational Training) program providing up to $1,300 for graduate students to attend computational workshops. Multiple groups including ECI, EIGH, GBCF, and HCRI collaborate on this initiative.

Scale indicators4 records

Recent moves9 records

Expansion highlights5 records

Direct peers

• Purdue University Genomics Core: CTSI partner institution core providing NGS and bioinformatics to Purdue researchers; serves the same regional Indiana CTSI customer pool and competes for shared CTSI grant funding.
• University of Oregon Genomics & Cell Characterization Core: Pfrender's alma mater and former collaborator (Bradshaw/Holzapfel mosquito genomics published in PNAS). Academic core offering overlapping services to biology researchers with similar non-model-organism focus.
• Indiana University Center for Genomics and Bioinformatics: Same-state genomics/bioinformatics core at Indiana University Bloomington; offers overlapping NGS and bioinformatics services to IU researchers and CTSI partners. Most direct institutional peer given geographic and partnership overlap.
• Notre Dame Genomics Core Facility (predecessor / sister): The same entity referenced in some records as the broader Notre Dame Genomics Core — a directly overlapping academic core offering similar sequencing and bioinformatics services to the same Notre Dame research community.
• University of Michigan Advanced Genomics Core: Big Ten academic genomics core offering NGS, single-cell, and spatial services to a large Midwestern research base. Directly comparable in mission, instrumentation, and academic-customer model.
• Mayo Clinic Genomics Core: Mayo Clinic operates a clinical/academic genomics core that supports translational research including cancer genomics — a direct peer given the Notre Dame-Mayo Clinic cancer research partnership disclosed in the data.

Broad incumbents

• Novogene Corporation: Global commercial sequencing services provider offering NGS, exome, transcriptome, and single-cell services at published per-sample pricing. Comparable in technology but commercial scale and geographic reach far exceed GBCF.
• Azenta Life Sciences (formerly GENEWIZ): Commercial genomics services provider with published pricing, web ordering, and global turnaround times for NGS, Sanger, and synthesis. Closest commercial analogue to the GBCF service model.
• Broad Institute Genomics Platform: Large-scale academic genomics platform offering NGS, single-cell, and spatial services at scale across a global research base. Comparable technology stack and service menu but vastly larger scale and external customer reach.

Others

• Eck Institute for Global Health (Notre Dame): Internal Notre Dame research institute that co-funds GBCF equipment and collaborates on REACT training. Not a competitor but a strategic cost-share partner whose continued funding directly supports GBCF capex.

Market position

Strengths5 records

Weaknesses3 records

Competitive moat5 records

Key risks7 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/ndgenomics

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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