What Gram BioLine does

Gram BioLine, operating under the legal entity Gram Scientific ApS, designs and manufactures professional-grade biostorage refrigerators and freezers for life science applications at a single facility in Vojens, Denmark. The portfolio spans seven product families covering the full temperature spectrum required in regulated laboratory work: BioUltra ultra-low temperature freezers at -86°C using cascade refrigeration and vacuum-insulated panels, BioPlus premium units from 500 to 1,400 liters, BioMidi mid-range 425 to 625 liter models, BioCompact II compact cabinets from 125 to 600 liters, BioBasic entry-level models, BioBlood blood bank and plasma storage (marketed outside the European Union), and ExGuard ATEX-certified hazardous-atmosphere storage. Supporting the hardware are the HELIX next-generation controller with touchscreen interface and data logging, the standardized MPC control unit, and a web-based product configurator that delivers instant pricing and PDF documentation. The Gram brand traces back to 1901, and the BioLine line was established in 2006; on January 1, 2023, the business was transferred from Gram Commercial (formerly a branch of Hoshizaki Europe BV) to the independent Gram Scientific ApS.

The company sells configured-to-order biostorage equipment directly from its Danish headquarters and through a network of regional distributors and sales agents in Germany, France, the Netherlands, Belgium, Norway, Sweden, and the United Kingdom. Customers include life-science laboratories, blood banks and transfusion services, pharmaceutical manufacturers operating under GMP, hospitals and pharmacies, and government analytical laboratories; pricing is not publicly listed but is generated through the online configurator and tailored to each specification. ATEX Cat. 3 Zone 2 compliance, ISO 9001, ISO 14001, ISO 13485, and DIN 58371/58375/13277 conformity kits are included as standard or low-friction options across the range. Documented wins include a €2.5M Danish Regions EU tender for clinical refrigeration and twelve consecutive months of 100% customer satisfaction across 3,700 after-sales inquiries, indicating an established installed base across European regulated life-science infrastructure.

Name

Gram BioLine

Legal name

Gram Scientific ApS

Website

https://gram-bioline.com

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

251–500 employees

Short description

Gram BioLine designs and manufactures professional-grade biostorage refrigerators and freezers in Vojens, Denmark, serving life-science laboratories, hospitals, blood banks, and pharmaceutical manufacturers across Europe via direct sales and a regional distributor network.

Ownership category

akta.pro rank

Product category

Biostorage Refrigeration Equipment

NAICS

Ventilation, Heating, Air-Conditioning, and Commercial Refrigeration Equipment Manufacturing (33341), Air-Conditioning and Warm Air Heating Equipment and Commercial and Industrial Refrigeration Equipment Manufacturing (333415), Refrigeration Equipment and Supplies Merchant Wholesalers (423740)

SIC

Air-Cond & Warm Air Heatg Equip & Comm & Indl Refrig Equip (3585), Refrigeration & Service Industry Machinery (3580)

akta.pro primary industry

Cold Chain, Cryopreservation & Biologics Storage/Handling Technologies (HLAAAJAN)

akta.pro secondary industries

Pharma & Biotech Cold Storage (2–8°C, CRT) (AFAOAFAG), Biologics, Vaccines & Ultra-Low Temperature (ULT) Storage (TLALABAG)

Keywords

• Biostorage refrigeration systems
• Laboratory freezers
• Pharmaceutical cold storage
• ATEX certified cabinets
• Ultra-low temperature freezers

Headquarters

HQ city

Vojens

HQ country

Denmark

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Biostorage Equipment Sales: Gram BioLine generates revenue primarily from the manufacture and sale of high-performance refrigerators and freezers for life science applications. Products are sold as configured units with custom interior layouts and optional features. All products are developed and manufactured at the Vojens, Denmark facility.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels4 records

Core offering

Gram BioLine designs, manufactures, and sells professional-grade biostorage refrigerators and freezers for life science applications, covering ultra-low temperature storage (-86°C), blood bank, pharmaceutical, hospital, and ATEX-regulated hazardous-material use cases. All products are developed and produced at the company's Vojens, Denmark facility and are sold as configured-to-order units through direct sales and a European distributor network.

Product overview

Gram BioLine offers a comprehensive portfolio of high-performance refrigerators and freezers for bioscience applications, including laboratories, hospitals, pharmaceutical, and industrial use. The product lineup consists of seven distinct biostorage solution families: BioUltra (ultra-low temperature freezers at -86°C with cascade refrigeration and VIP insulation), BioPlus (premium high-performance models, 500-1400L, -35°C to +20°C), BioMidi (mid-range models, 425-625L, -40°C to +20°C), BioCompact II (compact universal units, 125-600L), BioBlood (specialized blood bank storage for non-EU markets), BioBasic (cost-effective entry-level), and ExGuard (ATEX-certified hazardous material storage). Supporting these product lines are the HELIX next-generation controller with touchscreen interface and data logging, the MPC Control Unit providing standardized operation across models, and a Product Configurator for custom configuration. All products are developed and manufactured in Vojens, Denmark, with ATEX compliance included as standard without extra charge.

Differentiator

Problem solved

Functional benefit

Brands

• BioLine: Main product series brand for biostorage refrigerators and freezers for life science applications including laboratories, hospitals, and pharmaceutical industries.
• ExGuard
• BioUltra
• BioPlus
• BioMidi
• BioCompact II
• BioBlood
• BIOBASIC
• HELIX

Products and services

• BioUltra Ultra-low temperature freezer reaching -86°C for long-term storage of sensitive biological materials, using cascade refrigeration and VIP insulation to achieve ultra-low temperatures on a relatively small footprint. Designed for life science laboratories, pharmaceutical storage, and research applications requiring the most stringent temperature conditions.
• BioPlus Premium high-performance biostorage refrigerator and freezer series with capacities from 500 to 1400 liters and temperature range from -35°C to +20°C. Features top-mounted compressor and full stainless steel interior for the most sensitive biomaterials in pharmaceutical, hospital, and research environments.
• BioMidi Mid-range biostorage refrigerator and freezer with 425 or 625 liter capacities and temperature range from -40°C to +20°C, offering core BioPlus features at a more accessible price point. Designed for demanding biostorage requirements in laboratories and healthcare facilities.
• BioCompact II Compact universal refrigerator and freezer cabinet for general-purpose biostorage, available in 125 to 600 liter sizes operating as refrigerator (+2°C/+20°C) or freezer (-25°C/-5°C). Features forced air distribution, no cold walls, and internal/external ATEX compliance. DTI 22ATEX0251X certified for ATEX Cat. 3 Zone 2.
• BioBlood Specialized blood bank storage refrigerators and freezers in 425-1400 liter capacities, including blood refrigerator (BR: +2°C/+6°C), blood freezer (BF: -25°C/-5°C), and plasma freezer (PF: -35°C/-5°C to -40°C/-5°C). Compliant with DIN 58371 and DIN 58375. Exclusively available for markets outside the European Union.
• BioBasic Cost-effective biostorage cabinet range in 125L, 218L, 346L, and 600L capacities with adjustable wire shelves, integrated temperature alarms, internal and external ATEX protection, forced air cooling, and user-friendly control system. Targeted at price-sensitive laboratory and research users.
• ExGuard ATEX-certified storage cabinet for materials that may emit harmful, odorous, and/or explosive atmospheres. Features integrated ventilation activation and electromagnetic locking that purges potentially hazardous atmospheres before allowing user access. Complies with ATEX Category 3, Zone 2 requirements both internally and externally.

Quantifiable outcome

• 12 consecutive months of 100% customer satisfaction with 3700 after-sales inquiries handled
• +3 more outcomes

Named customers5 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Three partnerships are on record, tiered regional.

• Eberhardt (France)regionalChannel Partner/ Reseller/ Distributor · 1 January 2024Eberhardt serves as the French distributor for Gram BioLine products. Located at 18 rue des frères Eberts, F-67100 Strasbourg, France. Handles sales and support for the French market.
• Andersen Partners Business Center (Germany)regionalChannel Partner/ Reseller/ Distributor · 1 January 2024Andersen Partners Business Center in Hamburg serves as the German representative office for Gram BioLine, handling sales and distribution in the German market.
• Matrix Bedrijvencentrum (Netherlands and Belgium)regionalChannel Partner/ Reseller/ Distributor · 1 January 2024Matrix Bedrijvencentrum based in Almelo serves as the distributor for the Netherlands and Belgium, representing Gram BioLine products in the Benelux market.

Scale indicators3 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• PHCbi (formerly Panasonic Healthcare): Japanese-owned manufacturer of biomedical and pharmaceutical-grade refrigerators and ULT freezers with deep global reach; a primary competitor in the BioUltra -86°C segment and hospital pharmacy refrigeration market.
• B Medical Systems: Luxembourg-based manufacturer specializing in vaccine cold chain, blood bank refrigerators, and ULT freezers—the most direct competitor to Gram BioLine across life science and blood storage segments, with comparable product certifications and EU/global footprint.
• Helmer Scientific: US-based manufacturer of medical-grade blood bank refrigerators, plasma freezers, and pharmacy refrigeration—directly comparable in BioBlood product category and regulated medical storage segments.
• Arctiko: Danish-headquartered peer specializing in biomedical and laboratory ULT freezers and blood bank refrigerators; competes in the same Danish/nordic and European life-science refrigeration market as Gram BioLine.
• Haier Biomedical: Chinese manufacturer of biomedical refrigerators, ULT freezers, and cold chain storage with global distribution; competes in the same biostorage category with significant pricing pressure in EU tenders and emerging markets.
• Philipp Kirsch: German manufacturer of laboratory refrigerators, blood bank storage, and pharmacy refrigerators—overlaps directly with Gram BioLine's BioLine, BioBlood, and BioCompact II product lines in the DACH hospital/lab market.

Emerging players

• BINDER GmbH: German manufacturer of laboratory incubators, drying ovens, and ultra-low temperature freezers; comparable in regulated laboratory storage category with growing overlap in pharma stability and ULT biostorage segments.

Broad incumbents

• Eppendorf: Premium German life-science equipment manufacturer with laboratory freezers and cryopreservation storage in its portfolio; adjacent competitor at the higher end of the biostorage market and in pharma/biotech labs.
• Thermo Scientific (Thermo Fisher Scientific): Broad life-science equipment incumbent offering TSX and TDE series ULT freezers and lab refrigerators as part of a much wider portfolio; competes in ULT and lab refrigeration but does not specialize in biostorage the way Gram BioLine does.
• Liebherr (Laboratory and Medical segment): Major commercial refrigeration manufacturer with laboratory and medical-grade refrigerator/freezer lines; competes on reliability and brand in European lab markets but is a broader appliance player.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Gram BioLine