Brain Research Center
Brain Research Center is a Netherlands-based clinical research organization running Phase II neurology trials for Alzheimer's, Parkinson's, and Dementia with Lewy bodies at three Dutch sites, serving global pharmaceutical and biotech sponsors and licensing the proprietary Amsterdam IADL Questionnaire worldwide.
- Company typePrivate
- Founded2009
- HeadquartersAmsterdam, Netherlands
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Brain Research Center does
Brain Research Center is a Netherlands-based, privately-held clinical research organization (CRO) specializing in Phase II drug trials for neurological diseases, primarily Alzheimer's disease, Parkinson's disease, and Dementia with Lewy bodies. Founded in 2009 by Amsterdam UMC, the company operates three full-service research centers in Amsterdam, Den Bosch, and Zwolle, staffed by a permanent team of neurologists, geriatricians, neuropsychologists, and study coordinators. The organization has executed 75 clinical trials enrolling more than 500 participants and is ISO9001-certified, GCP-compliant, and operates a GDPR-compliant proprietary patient management system with in-house laboratory capabilities.
The company generates revenue through three streams: (1) full-service clinical trial execution for pharmaceutical and biotech sponsors, (2) consultancy services for trial design, endpoint definition, and regulatory strategy, and (3) commercial licensing of the proprietary Amsterdam IADL Questionnaire — a psychometrically valid outcome measure for everyday functioning in dementia, available in 28 languages and adopted in 23 trials. Sponsors include Biogen, Roche, MSD, EIP Pharma, and AriBio. Strategic academic and hospital partners include Amsterdam UMC, Jeroen Bosch Hospital, and Isala. Distribution is primarily domestic (Netherlands) with growing global reach via the IADL Questionnaire licensing arm.
Brain Research Center firmographics
Firmographics- Name
- Brain Research Center
- Legal name
- Brain Research Center Holding B.V.
- Website
- https://brainresearchcenter.nl
- Company type
- Private
- Founded year
- 2009
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Brain Research Center is a Netherlands-based clinical research organization running Phase II neurology trials for Alzheimer's, Parkinson's, and Dementia with Lewy bodies at three Dutch sites, serving global pharmaceutical and biotech sponsors and licensing the proprietary Amsterdam IADL Questionnaire worldwide.
- Ownership category
- akta.pro rank
Brain Research Center industry classification
Industry- Product category
- Clinical Research Services
- NAICS
- Scientific Research and Development Services (5417), Other Scientific and Technical Consulting Services (54169)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Specialty Therapeutic-Area CROs (e.g., oncology/rare disease) (HLAGAAAL)
- akta.pro secondary industries
- Clinical CROs (Phase I–IV) (HLAGAAAA), Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI)
Keywords
Where Brain Research Center is headquartered
LocationHeadquarters
- HQ city
- Amsterdam
- HQ country
- Netherlands
- HQ region
- Europe
Offices4 records
Markets served
Brain Research Center business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales
Revenue model
- Clinical Trial Execution Services: Full-service clinical research execution for pharmaceutical companies, biotechs, and CROs. Services include participant recruitment, screening, and trial conduct across three research centers covering most of the Netherlands.
- Clinical Consultancy: Advisory services for design, implementation, and supervision of clinical trials. Includes study protocol development, endpoint definition, and inclusion/exclusion criteria. Consultants can serve on clinical advisory boards and regulatory meetings.
- Amsterdam IADL Questionnaire Licensing: Commercial licensing of the Amsterdam IADL Questionnaire for use in clinical trials. Partnership established with Amsterdam UMC in January 2022 for global commercial distribution.
Go-to-market motion3 records
Distribution channels3 records
Marketing channels5 records
Brain Research Center product offering
Product offeringCore offering
Brain Research Center is a full-service clinical research organization (CRO) that executes Phase II clinical trials for new drug candidates targeting Alzheimer's disease, Parkinson's disease, Dementia with Lewy bodies, and other neurological conditions. It operates three dedicated research centers in the Netherlands (Amsterdam, Den Bosch, Zwolle) staffed by neurologists, geriatricians, neuropsychologists, and study coordinators, providing participant recruitment, pre-screening, full trial conduct, and consultancy/advisory services to pharmaceutical, biotech, and CRO clients.
Product overview
Brain Research Center operates as a full-service clinical research organization connecting patients, pharmaceutical companies, biotech companies, and medical specialists to find breakthrough treatments for brain diseases. The company offers two core services: Trial Execution Services (conducting clinical trials at three full-service research centers in Amsterdam, Den Bosch, and Zwolle) and Consultancy Services (expert advisory for clinical trial design and regulatory support). An additional offering is the Amsterdam IADL Questionnaire, a validated outcome measure for dementia trials developed in partnership with Amsterdam UMC. The company conducts clinical trials across three therapeutic areas: Alzheimer's disease, Parkinson's disease, and Dementia with Lewy bodies, with multiple active drug candidates in Phase II development.
Differentiator
Problem solved
Functional benefit
Brands
- Amsterdam IADL Questionnaire: A psychometrically valid outcome measure developed to measure meaningful and early changes in everyday functioning for dementia patients. Brain Research Center coordinates commercial licensing of this questionnaire in partnership with Amsterdam UMC.
Products and services
- Trial Execution Services Full-service clinical trial execution at three research centers in Amsterdam, Den Bosch, and Zwolle, covering most of the Netherlands. The service includes participant recruitment, pre-screening, and complete trial conduct with a team of experienced doctors, neuropsychologists, and study coordinators for pharmaceutical, biotech, and CRO clients developing neurological therapies.
- Consultancy Services Expert advisory services for designing, implementing, and supervising clinical trials, including study protocol development, endpoint definition, and inclusion/exclusion criteria. Provides access to international knowledge networks in neurology and geriatrics, with consultants serving on clinical advisory boards and regulatory meetings for biotech, pharma, and CRO clients.
- Amsterdam IADL Questionnaire Psychometrically valid outcome measure for assessing Instrumental Activities of Daily Living (IADL) in early dementia, developed in partnership with Amsterdam UMC. Covers modern everyday technology and is suitable for younger populations under 65. Uses Item Response Theory (IRT) scoring for interval-level properties and is commercially licensed for use by sponsors and research organizations running dementia clinical trials.
Quantifiable outcome
- 38 participants randomized in PRImus-AD study, nearly double the original target
- +2 more outcomes
Companies that use Brain Research Center
Customer profileNamed customers6 records
Segments3 records
Ideal customer profiles3 records
Brain Research Center technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration6 records
Feature3 records
Brain Research Center partnerships and signals
Strategic signalPartnerships
Eleven partnerships are on record, tiered core.
- Amsterdam UMCcoreFounding partner - Brain Research Center was established in 2009 by Amsterdam UMC. Partnership for the Amsterdam IADL Questionnaire commercial licensing established in January 2022. Amsterdam UMC conducts research (e.g., Efavirenz study) commissioned through Brain Research Center.
- Jeroen Bosch HospitalcoreStrategic partner for clinical research operations. Hospital serves as referral source and collaborative partner in brain disease research.
- IsalacoreStrategic partner for clinical research operations, particularly for the Zwolle location and surrounding region.
- PRinnovation GmbHcoreSponsor of the PRImus-AD study (Phase II trial for PRI-002 in Alzheimer's). Collaboration enabled successful recruitment exceeding targets by nearly double.
- Julius ClinicalcoreCollaborative partner in the PRImus-AD study. Partnership credited for successful recruitment strategy and achievement of study goals.
- EIP PharmacoreSponsor of the RewinD-LB study evaluating neflamapimod for Dementia with Lewy bodies treatment.
- BiogencoreSponsor of Celia study (BIIB080 for Alzheimer's) and LUMA study (BIIB122 for Parkinson's disease).
- RochecoreSponsor of Selnoflast study for Parkinson's disease treatment.
- AriBiocoreSponsor of Polaris AD study (AR1001) for early Alzheimer's disease treatment.
- Merck Sharp & Dohme (MSD)coreSponsor of MK-1167 study for mild to moderate Alzheimer's disease.
- Amsterdam UMC (Research)coreCommissioned Efavirenz study for early Alzheimer's disease treatment. Research conducted based on Amsterdam UMC findings about cholesterol accumulation in Alzheimer's development.
Scale indicators7 records
Recent moves6 records
Expansion highlights5 records
Brain Research Center competitors and assessment
Company assessmentDirect peers
- Worldwide Clinical Trials: Mid-sized specialty CRO with a strong neuroscience focus, running Phase I–III neurology and rare-disease trials for pharma sponsors. Comparable to BRC because both compete for the same sponsor neurology trial budget, though Worldwide is materially larger and global.
- CTI Clinical Trial & Consulting Services: Specialty CRO with therapeutic depth in neurology, rare disease, and immunology. Comparable as a mid-sized sponsor-facing CRO competing for neurology Phase II/III trial work, but with broader geographic reach than BRC.
- Julius Clinical: Netherlands-based academic CRO and existing BRC partner. Comparable because both run neuroscience and metabolic trials from a Dutch hub, though Julius operates as a project-management CRO across multiple European sites rather than a dedicated site network.
Broad incumbents
- Medpace: Mid-to-large full-service global CRO with a strong neuroscience therapeutic unit. Comparable as a competing trial-execution vendor for the same pharma sponsors, but it offers full-service global operations versus BRC's Dutch-only site specialization.
- ICON plc: Large global CRO with dedicated biotech and CNS franchises. Comparable as a competitor for sponsor neurology Phase II/III contracts; competes at materially larger scale and breadth than BRC.
- Parexel International: Top-tier full-service CRO with significant neuroscience and rare disease trial execution. Comparable as a competing full-service vendor for the same pharma neuroscience budgets, but operating globally versus BRC's local Dutch footprint.
- IQVIA: World's largest CRO with deep neuroscience and Alzheimer's trial experience. Comparable as the dominant competitor for sponsor neurology trial execution; BRC often serves as a specialty sub-site within IQVIA-managed studies.
- Syneos Health: Large full-service biopharma solutions provider covering clinical development and commercialization across CNS and other therapeutic areas. Comparable as a competing CRO for sponsor CNS trial work at significantly larger scale and geographic reach.
- Charles River Laboratories: Global CRO and preclinical services provider with CNS trial capabilities among others. Comparable in offering trial services to the same pharma neuroscience clients, though it spans preclinical through clinical at much larger scale.
Emerging players
- Bioskin: Specialty CRO with neurology and dermatology focus running Phase II–IV trials. Comparable as a niche neurology CRO competing for similar sponsor budgets, though smaller and less established in Alzheimer's pivotal trials than BRC.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights6 records
Customer concentration
Brain Research Center social profiles
Digital presenceBrain Research Center compliance and trust
Trust signalCompliance3 records
Brain Research Center financial estimates
Financial estimateRevenue estimate
Valuation estimate
Brain Research Center leadership team
Management profileNumber of profiles
Profiles6 records
Brain Research Center funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Brain Research Center M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Brain Research Center
What does Brain Research Center do?
Brain Research Center is a full-service clinical research organization (CRO) that executes Phase II clinical trials for new drug candidates targeting Alzheimer's disease, Parkinson's disease, Dementia with Lewy bodies, and other neurological conditions. It operates three dedicated research centers in the Netherlands (Amsterdam, Den Bosch, Zwolle) staffed by neurologists, geriatricians, neuropsychologists, and study coordinators, providing participant recruitment, pre-screening, full trial conduct, and consultancy/advisory services to pharmaceutical, biotech, and CRO clients.
Is Brain Research Center a public or private company?
Brain Research Center is a private company. It is classified as unknown and is currently operating.
When was Brain Research Center founded?
Brain Research Center was founded in 2009. It employs 11 to 50 people.
Where is Brain Research Center based?
Brain Research Center is headquartered in Amsterdam, Netherlands, in the Europe region.
How does Brain Research Center make money?
Three revenue lines are on record. Clinical Trial Execution Services are the primary driver. The others are clinical Consultancy and amsterdam IADL Questionnaire Licensing.
Who are Brain Research Center's main competitors?
Direct peers on record are Worldwide Clinical Trials, CTI Clinical Trial & Consulting Services and Julius Clinical. Broad incumbents are Medpace, ICON plc, Parexel International, IQVIA, Syneos Health and Charles River Laboratories. Bioskin is listed as an emerging player.
Does Brain Research Center have an API?
No public API is recorded for Brain Research Center.
What industry is Brain Research Center in?
Brain Research Center's product category is Clinical Research Services. Its primary akta.pro industry code is HLAGAAAL, Specialty Therapeutic-Area CROs (e.g., oncology/rare disease), with a secondary code of HLAGAAAA, Clinical CROs (Phase I–IV). Its NAICS code is 5417 and its SIC code is 8731.