San Raffaele

What San Raffaele does

San Raffaele S.p.A. is a privately held Italian healthcare company headquartered in Rome at Via di Val Cannuta 247, operating an integrated healthcare network (the 'SR Network') spanning hospitals, rehabilitation centers, residential care facilities (RSA), outpatient clinics, and home care services across Lazio, Abruzzo, Puglia, Basilicata, Campania, and Sardinia. The network comprises over 4,000 inpatient and residential beds and employs more than 4,000 health professionals, with services delivered through both Italian National Health Service (SSN) accreditation via regional ASL (Aziende Sanitarie Locali) agreements and private-pay channels. The company is structured around 14+ wholly-owned operating subsidiaries (S.r.l. entities), each holding separate SSN accreditations, and includes the IRCCS San Raffaele research hospital and the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET) as scientific research anchors.

The core technology stack combines advanced diagnostic imaging—including Siemens MAMMOMAT Inspiration PRIME Edition 3D mammography with tomosynthesis (up to 30% dose reduction) and the newly inaugurated digital PET-CT scanner with AI integration at IRCCS San Raffaele Cassino—with rehabilitation technologies such as EKSO and ATLAS 2030 robotic exoskeletons for adult and pediatric neurorehabilitation respectively. The SR-TIGET gene therapy platform supports parallel development of therapies for lysosomal storage diseases (MPS IVA, GLB1-related disorders, and alpha-mannosidosis), and in March 2026 established the first Danaher Beacon in continental Europe via a multi-year partnership with Cytiva, Aldevron, and IDT to advance lentiviral vector production and gene editing. Digital infrastructure includes the SR Telemedicina platform for remote consultations, an integrated Single Reservation Center (CUP), online booking (prenotazioni.sanraffaele.it), and the Referti Online portal for report retrieval.

San Raffaele's business model operates through five principal revenue streams: regulated SSN tariff reimbursement across the accredited facility network; private-pay outpatient services and promotional screening packages (e.g., the SR Donna women's health screening package at €120); continuing medical education (ECM) courses delivered through its national ECM Provider status; PNRR and Fondazione Telethon research grants supporting SR-TIGET gene therapy programs; and ancillary services including home care (ADI – Assistenza Domiciliare Integrata). Customer access flows through GP/ASL referrals for SSN services, direct-to-consumer booking for private-pay offerings, and centralized Customer Care for international patients, with go-to-market spanning institutional SSN contracts, scientific conference participation, and event-driven reputation building.

Name

San Raffaele

Legal name

San Raffaele S.p.A.

Website

https://sanraffaele.it

Company type

Private

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

San Raffaele S.p.A. operates an integrated Italian healthcare network (SR Network) of 16+ hospitals, rehabilitation centers, nursing homes, and outpatient clinics across Lazio, Abruzzo, Puglia, Basilicata, and Sardinia, with 4,000+ beds and 4,000+ health professionals serving general, rehabilitation, and elderly patients through SSN-accredited and private-pay services, including the IRCCS research hospital and the SR-TIGET gene therapy institute.

Ownership category

akta.pro rank

Product category

Integrated Healthcare and Rehabilitation Services

NAICS

Home Health Care Services (62161), Nursing Care Facilities (Skilled Nursing Facilities) (62311), Diagnostic Imaging Centers (621512), Services for the Elderly and Persons with Disabilities (624120), Services for the Elderly and Persons with Disabilities (62412)

SIC

Services-Home Health Care Services (8082), Services-Skilled Nursing Care Facilities (8051), Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Nursing & Personal Care Facilities (8050)

akta.pro primary industry

Home Health Therapy Services (PT/OT/SLP) Providers (HLAFAEAM)

akta.pro secondary industries

Virtual Specialty Care Platforms (tele-stroke, tele-ICU, tele-derm, tele-cardiology) (HLALABAD), Decentralized & Hybrid Trial Site Services (Home Health/Nursing) (HLAGACAH), Hospital-at-Home & Acute-at-Home Remote Monitoring (step-down, escalation workflows) (HLALAFAH), Private Duty 24/7 Nursing (RN/LPN) In-Home Care (HSABAHAJ)

Keywords

• Rehabilitation services
• Residential elderly care
• Diagnostic imaging
• Neurorehabilitation programs
• Home healthcare services

Headquarters

HQ city

Roma

HQ country

Italy

HQ region

Europe

Offices18 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales, Supply Chain

Revenue model

1. Healthcare Service Delivery: Direct revenue from patient care services delivered across the SR Network of hospitals, rehabilitation centers, nursing homes (RSA), outpatient clinics, and home care (ADI). Services are provided both through the National Health Service (SSN/accreditation) and as private-pay. Revenue is generated from diagnostic procedures, specialist visits, inpatient stays, rehabilitation programs, and home care.
2. National Health Service (SSN) Accreditations: Facilities operate under regional health system accreditation agreements, with funding flows from ASL (Aziende Sanitarie Locali) based on authorized capacity and service volume. Multiple subsidiaries hold separate SSN accreditations (Casa di Cura Nepi, Centro Geriatrico Matera, IRCCS San Raffaele Roma, Medica Group, Montecompatri, Nuova Nomentana Hospital, Portuense, Residenza dei Renai, Rocca di Papa, Rosa del Marganai, RSA San Raffaele Sabaudia, San Raffaele S.p.A., Villa dei Fiori, Villa Monica, Viterbo, SGAS).
3. Continuing Medical Education (ECM): The San Raffaele Training Center is a National ECM Provider recognized by the Commissione Nazionale per la Formazione Continua, generating revenue from accredited training courses for healthcare professionals.
4. Research Grants and PNRR Funding: IRCCS San Raffaele participates in projects funded by Italy's National Recovery and Resilience Plan (PNRR), with grants supporting gene therapy research, robotics rehabilitation, and translational medicine. Fondazione Telethon co-funds SR-TIGET gene therapy programs.
5. Private-Pay Diagnostic and Screening Packages: Direct consumer revenue from promotional screening packages (e.g., SR Donna breast screening at €120) and private specialist consultations not covered by SSN.

Pricing tiers

Go-to-market motion3 records

Distribution channels7 records

Marketing channels8 records

Core offering

San Raffaele S.p.A. operates the SR Network, an integrated Italian healthcare system providing diagnostic imaging, specialist outpatient care, inpatient and residential rehabilitation (RSA), home care (ADI), and telemedicine through more than 16 facilities with 4,000+ beds and 4,000+ health professionals. Services are delivered both under Italian National Health Service (SSN) accreditation and as private-pay offerings, with a research arm (IRCCS San Raffaele and SR-TIGET) advancing gene therapy and neurorehabilitation science.

Product overview

San Raffaele is a comprehensive healthcare network (SR Network) providing integrated healthcare, scientific research, and assistance services through over 40 facilities with more than 4,000 beds and 4,000 health professionals. The network offers diagnostic imaging services (including 3D mammography with tomosynthesis, digital PET-TC with AI), rehabilitation services (neuromotor, equestrian rehabilitation, developmental age), telemedicine (SR Telemedicina), home care (ADI), outpatient specialist clinics, and operates research institutes including IRCCS San Raffaele for neuroscience and the San Raffaele-Telethon Institute for Gene Therapy. Patients can access services through online booking (CUP) and digital report retrieval.

Differentiator

Problem solved

Functional benefit

Products and services

• SR Network (San Raffaele Healthcare Network) Integrated healthcare network providing diagnostics, specialist outpatient care, inpatient rehabilitation, residential elderly care (RSA), home care (ADI), and research services across multiple Italian regions.
• Outpatient Specialist Clinics SSN-affiliated outpatient clinics offering specialist services including cardiology, dermatology, diagnostic imaging, endocrinology, gynecology, neurology, orthopedics, otolaryngology, physiatrics, speech therapy, ultrasound, and urology.
• Specialized Rehabilitation Services (Neurorehabilitation and Equestrian Rehabilitation) Specialized rehabilitation including physical, mental, and sensory rehabilitation, equestrian rehabilitation, onotherapy, robotic exoskeleton therapy (EKSO, ATLAS 2030), music therapy, and neuroprosthetics. Includes 95 residential beds and 35 semiresidential beds at San Raffaele Viterbo.
• ADI – Assistenza Domiciliare Integrata (Integrated Home Care) Integrated home care service delivering healthcare assistance to patients in their homes across the SR Network catchment area.
• SR Telemedicina Telemedicine service enabling remote medical consultations, online report access, and home care coordination.
• San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET) Research institute developing gene therapy platforms for lysosomal storage diseases (MPS IVA, GLB1-related disorders, alpha-mannosidosis) and next-generation genomic medicine including lentiviral vector production and gene editing in hematopoietic stem cells.
• IRCCS San Raffaele Neuroscience and Neurorehabilitation Unit Research and clinical unit focused on neuroscience and neurorehabilitation, including the CDCD (Centro Disturbi Cognitivi e Demenze), formally recognized as a Center of Excellence by Lazio Region.
• San Raffaele Formazione (Continuing Medical Education / ECM Provider) National ECM Provider delivering accredited continuing medical education and specialized training programs for healthcare professionals.
• SR Donna Women's Health Screening Package Private-pay women's health screening package combining gynecological consultation, Pap test, mammography, and breast ultrasound for early detection of breast and gynecological conditions.
• Residential Care (RSA) Services Residential, semi-residential, hospice, and integrated home care services for elderly and non-self-sufficient adults, including dementia care (CDCD), across multiple SSN-accredited facilities.

Quantifiable outcome

• Up to 30% dose reduction in mammography with maintained image quality (PRIME technology)
• +4 more outcomes

Named customers5 records

Segments7 records

Ideal customer profiles8 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability1 record

Feature7 records

Partnerships

Eight partnerships are on record, tiered flagship, supporting, core and minor.

• Cytiva (Danaher company)flagshipStrategic or Co-development Partner · 23 March 2026Cytiva and SR-TIGET launched a multi-year collaboration to advance next-generation genomic medicine platforms, establishing the first Danaher Beacon on the European continent. The initiative focuses on optimizing lentiviral vector production and homology-directed repair-based gene editing in hematopoietic stem cells. SR-TIGET provides scientific leadership while Cytiva provides manufacturing expertise. Partners Aldevron and IDT also participate. The goal is to help developers overcome bottlenecks in cell and gene therapy translation, scalability, and reproducibility to make breakthrough advanced therapies more sustainable and accessible to patients.
• AldevronsupportingTechnology or Integration · 23 March 2026Aldevron participates as a technology partner alongside Cytiva in the SR-TIGET genomic medicine collaboration, contributing to the Danaher Beacon initiative for cell and gene therapy manufacturing optimization.
• IDTsupportingTechnology or Integration · 23 March 2026IDT participates alongside Cytiva and Aldevron in the SR-TIGET collaboration as a technology partner contributing to the Danaher Beacon genomic medicine platform for gene editing optimization.
• Tosinvest SanitàcoreStrategic or Co-development Partner · 26 November 2004Tosinvest Sanità is the parent healthcare group of San Raffaele, organizing quality initiatives such as the World Quality Day in Healthcare with Fondazione San Raffaele, attended by Italian Ministry of Health officials. The group oversees the SR Network of healthcare facilities.
• WHO (World Health Organization)minorStrategic or Co-development Partner · 17 November 2004San Raffaele served as venue and institutional partner for World COPD Day conference organized by the Italian Association of COPD Patients, under the auspices of the WHO and NIH, recognizing San Raffaele's translational research role in rehabilitation and prevention.
• NIH – National Institutes of Health, BethesdaminorStrategic or Co-development Partner · 17 November 2004NIH Bethesda co-sponsored the World COPD Day conference held at San Raffaele, acknowledging San Raffaele's scientific contributions to respiratory rehabilitation and prevention research.
• Ospedale Bambino GesùsupportingStrategic or Co-development PartnerIRCCS San Raffaele and Ospedale Bambino Gesù jointly organize the International Epilepsy Course (XIII edition in Tagliacozzo), combining clinical and research expertise in pediatric and adult epilepsy.
• AREDA – Amateur Sports AssociationsupportingOthersAREDA provides technical support for equestrian rehabilitation activities at San Raffaele Viterbo's Equestrian Rehabilitation Center, including free-roaming Haflinger horses for therapy, mini ponies for children, and donkey onotherapy sessions.

Scale indicators11 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Gruppo San Donato: Italy's largest private hospital group, which notably owns the IRCCS Ospedale San Raffaele in Milan (distinct from the Rome-based San Raffaele S.p.A. analyzed here). Comparable as an Italian multi-facility hospital network with research capabilities and SSN-accredited operations.
• Korían Group: Major European operator of nursing homes, rehabilitation clinics, and home care services with operations in France, Italy, Germany, and beyond. Comparable to San Raffaele's residential, rehabilitation, and home care (ADI) service lines.
• emeis (formerly Orpea): Large European operator of nursing homes, post-acute and rehabilitation clinics. Comparable for the RSA/nursing home and rehabilitation components of San Raffaele's network, though at significantly larger scale.

Direct peers

• Humanitas: Italian private hospital group with IRCCS-recognized research (Humanitas Research Hospital) and integrated care across multiple specialties. Directly comparable to San Raffaele as an Italian multi-site hospital/research network with SSN accreditation and academic partnerships.
• Kos Group: Italian healthcare group operating hospitals, rehabilitation centers, nursing homes (RSA), and home care services. Closely matches San Raffaele's mix of rehabilitation, residential care, and acute services in Italy.
• Villa Maria Group: Italian private hospital and rehabilitation network with multiple facilities across regions. Comparable for multi-site Italian hospital/rehabilitation operations and SSN accreditation model.
• Segesta Group (Lifenet): Italian private healthcare operator focused on rehabilitation, RSA residential care, and psychiatric services. Directly comparable to San Raffaele's rehabilitation and elderly care footprint in central Italy.
• Affidea: European operator of advanced diagnostic imaging centers (MRI, CT, PET-CT) including in Italy. Comparable to San Raffaele's diagnostic imaging investments (digital PET-CT, 3D mammography) at the facility/outpatient level.
• Policlinico Universitario A. Gemelli IRCCS: Major Italian IRCCS university hospital in Rome with strong research portfolio. Comparable to IRCCS San Raffaele Roma in terms of designation, research prestige, and acute specialty services within the same metropolitan market.

Others

• Fondazione Telethon: Italian non-profit funding gene therapy research, long-standing co-funder of SR-TIGET. Adjacent player — represents the demand-side ecosystem for San Raffaele's gene therapy platform rather than a direct competitor.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/SanRaffaelespa
• YouTubeyoutube.com/@sanraffaelespa
• Facebookfacebook.com/sanraffaele.official
• LinkedInlinkedin.com/company/san-raffaele/mycompany
• Instagraminstagram.com/san.raffaele

Revenue estimate

Valuation estimate

Number of profiles

Profiles13 records

Subsidiaries15 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about San Raffaele