Sanford Guide

What Sanford Guide does

Sanford Guide, operated by Antimicrobial Therapy, Inc., is a privately held, family-owned medical reference publisher founded in 1969 and headquartered in Sperryville, Virginia. The company produces clinician-facing antimicrobial therapy decision-support content used in 100+ countries, with flagship products including the Sanford Guide Antimicrobial Therapy reference, the Sanford Guide Pediatric Acute Care reference, and a mobile application. Its content is curated and continuously updated by an editorial board of infectious-disease specialists from major academic medical centers, with a stated policy of editorial independence from pharmaceutical industry sponsorship.

The company's product surface has expanded beyond a print reference into a multi-format digital subscription business: individual clinician subscriptions are priced between $4.99 and $79.99, with print editions sold between $37.99 and $57.99, while institutional customers license content via Single Sign-On (SSO) integration into hospital workflows on a quote-based enterprise basis. Additional products include Stewardship Assist, an antimicrobial stewardship workflow platform, and GuidelineHQ, a white-label platform that allows partner organizations to deploy Sanford Guide content within their own branded digital properties. The longest-standing institutional relationship is a white-label partnership with the European AIDS Clinical Society (EACS) in place since 2012.

The business model spans individual subscriptions (B2C), enterprise SSO licensing to hospitals and health systems (B2B), white-label platform licensing via GuidelineHQ, print sales, and ancillary merchandise. Visible enterprise customers include major U.S. health systems such as HCA, Sutter Health, Tampa General, Piedmont, Bon Secours Mercy, MedStar, and Phoenix Children's, and the company has reported formal collaborations with the U.S. Centers for Disease Control and Prevention (CDC, 2023) and engagement with a Centers for Medicare & Medicaid Services (CMS) prior-authorization effort (May 2026).

Name

Sanford Guide

Legal name

Antimicrobial Therapy, Inc.

Website

https://sanfordguide.com

Company type

Private

Founded year

1969

Operating status

Operating

Headcount range

11–50 employees

Short description

Sanford Guide, operated by Antimicrobial Therapy, Inc., is a privately held medical reference publisher founded in 1969 that produces clinician-facing antimicrobial therapy decision-support content used in 100+ countries, serving individual clinicians, hospitals, and white-label partners via digital, print, and enterprise SSO subscriptions.

Ownership category

akta.pro rank

Headquarters

HQ city

Sperryville

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure, Supply Chain

Revenue model

1. Digital Antimicrobial Therapy Subscriptions: Recurring individual digital subscriptions for the Sanford Guide to Antimicrobial Therapy across web ($59.99), mobile ($34.99), and All Access ($79.99) tiers, plus add-on US Vaccine Guidelines ($4.99). The All Access subscription provides a hybrid usage across web, mobile, and full content.
2. Print Edition Sales: One-time sales of physical reference books in three formats: Pocket Edition ($37.99), Spiral Edition ($47.99), and Library Edition ($57.99).
3. Institutional / Enterprise Licensing (Stewardship Assist SSO): Site-license / enterprise agreements with hospitals, health systems, and academic medical centers for Stewardship Assist and Antimicrobial Therapy with single sign-on, sold to entities such as HCA, Sutter Health, Piedmont Healthcare, Tampa General Hospital, UF Health-Shands, MedStar, Bon Secours Mercy Health, and Phoenix Children's.
4. GuidelineHQ White-Label Licensing: OEM / white-label licensing of the GuidelineHQ platform to medical societies for branded clinical guideline delivery; powering branded guideline delivery in 100+ countries including the European AIDS Clinical Society (EACS) since 2012.
5. Specialty Products & Merchandise: One-time sales of specialty items including the Pediatric Acute Care guide ($49.99), Empiric! Card Game ($15.99), and Spectra of Activity Mug ($19.99).

Pricing tiers

Go-to-market motion4 records

Distribution channels5 records

Marketing channels7 records

Core offering

Sanford Guide (Antimicrobial Therapy, Inc.) publishes and licenses point-of-care clinical references for infectious disease and pediatric acute care treatment. The portfolio centers on The Sanford Guide to Antimicrobial Therapy and The Sanford Guide to Pediatric Acute Care, delivered as digital subscriptions (web, mobile, all-access), print editions (Pocket, Spiral, Library), and supplemented by the Stewardship Assist institutional add-on and the GuidelineHQ white-label platform for medical societies.

Product overview

Sanford Guide (Antimicrobial Therapy, Inc.) is a family-owned clinical reference company founded in 1969 that sells a two-product core portfolio — The Sanford Guide to Antimicrobial Therapy and The Sanford Guide to Pediatric Acute Care — each delivered via digital subscriptions (web, mobile, all-access) and print editions (Pocket, Spiral, Library), with free clinical calculators such as the Vanco AUC24 Calculator, an antibiotic stewardship card game (Empiric!), and accessories. Both core references are supported by a free monthly ID Update newsletter and dedicated multi-institutional editorial boards. On top of this core, Sanford Guide offers the Stewardship Assist add-on module for hospitals/health systems (which localizes the app and website with institutional antibiograms and guidelines) and GuidelineHQ, a separate white-label app/web platform that lets medical societies and health systems publish their own branded guidelines — built on 15 years of Sanford Guide guideline technology. Subscription and print tiers are listed at sanfordguide.com, and the platform also offers an institutional SSO option for hospitals plus bundled offerings such as the Antimicrobial + infektioStandards subscription.

Differentiator

Problem solved

Functional benefit

Brands

• Stewardship Assist: A guideline technology platform that places an institution's antimicrobial guidelines and antibiograms inside the Sanford Guide app and website for hospitals and health systems.
• GuidelineHQ
• The Sanford Guide to Antimicrobial Therapy
• The Sanford Guide to Pediatric Acute Care

Products and services

• The Sanford Guide to Antimicrobial Therapy Treatment-led, evidence-based, continuously updated clinical reference for infectious diseases. Available as digital subscriptions (All Access, Web, Mobile, and Mobile + U.S. Vaccine Guidelines bundles) and print editions (Pocket, Spiral, Library). For physicians, pharmacists, nurses, NPs, PAs, and students; includes 15+ clinical calculators, interactive Spectra of Activity, and U.S. Vaccine Guidelines content.
• The Sanford Guide to Pediatric Acute Care Point-of-care pediatric acute care reference covering manifestations, diagnostics, and management for children in acute care settings. Built for pediatric hospitalists, emergency physicians, urgent care providers, and residency programs. Available as a digital subscription (MSRP $49.99) on app and web.
• Stewardship Assist Platform Institutional add-on module that places an institution's own antimicrobial guidelines and antibiograms inside the Sanford Guide app and website. Supports SAML-based single sign-on (SSO) and is used by hospitals and health systems including HCA, Sutter Health, Tampa General Hospital, Piedmont Healthcare, and Bon Secours Mercy Health. Institutions report 3x more prescribers consulting their guidelines after deployment.
• GuidelineHQ Custom-branded white-label app and website platform for medical societies and health systems to deliver their own clinical practice guidelines, algorithms, and decision tools. Includes editorial dashboard with versioning, push updates, usage analytics, custom app icons/colors, and custom domain on iOS, Android, and web. Sold via OEM/white-label licensing.
• Empiric! Sanford Guide Edition Antibiotic Card Game Physical antibiotic stewardship card game designed to reinforce empiric antibiotic selection for trainees and clinicians, priced at $15.99.
• Spectra of Activity Mug Ceramic mug featuring the Spectra of Activity reference table, priced at $19.99 as a branded accessory.
• Sanford Guide Antimicrobial + infektioStandards Bundle Bundled subscription combining the Sanford Guide Antimicrobial Therapy content with infektioStandards (antimicrobial susceptibility reference), marketed to institutions and prescribers needing German/European standard data alongside Sanford Guide content.

Quantifiable outcome

• Used by clinicians in 100+ countries
• +2 more outcomes

Named customers23 records

Segments7 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

Feature6 records

Partnerships

Two partnerships are on record, tiered major and flagship.

• Centers for Disease Control and Prevention (CDC)majorStrategic or Co-development Partner · 1 June 2023Collaboration announced in June 2023 with the US Centers for Disease Control and Prevention to increase the availability of antimicrobial and infectious disease guidance. Specifics of joint activities (e.g., co-developed content, distribution channels, or funding) are not fully described in the available source material.
• European AIDS Clinical Society (EACS)flagshipOEM/ Whitelabel/ Licensing Partner · 1 January 2012Long-term partnership since 2012 in which Sanford Guide's GuidelineHQ platform powers branded clinical guideline delivery for the European AIDS Clinical Society. The platform powers branded guideline delivery in 100+ countries through this and other society relationships. This is an OEM / white-label arrangement where Sanford Guide provides the underlying technology and EACS provides the clinical content and brand.

Scale indicators5 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Epocrates: Mobile-first clinical reference for drug information, dosing, and infectious disease guidance used by individual prescribers; comparable to Sanford Guide in target user (prescribing clinicians), mobile delivery model, and point-of-care use case.
• Micromedex: Merative's clinical drug and disease reference suite used by hospitals and pharmacists for point-of-care decision support; directly overlaps with Sanford Guide's antimicrobial and pediatric content, with comparable enterprise licensing and pharmacy-led GTM.
• DynaMed: EBSCO's evidence-based clinical reference delivered via web and mobile to individual clinicians and institutions; competes head-to-head with Sanford Guide for hospital SSO licensing and clinician subscriptions, with a similarly curated, frequently updated editorial model.
• UpToDate: Wolters Kluwer's flagship evidence-based clinical decision support resource used at the point of care by physicians, pharmacists, and other clinicians; directly competes with Sanford Guide for institutional site licenses and individual clinician subscriptions, with broader specialty coverage.
• Lexicomp: Wolters Kluwer's drug information and clinical decision support suite widely licensed by hospital pharmacies and health systems; directly comparable to Sanford Guide in drug dosing, antimicrobial content, and institutional pharmacy/SSO buying motion.
• Johns Hopkins ABX Guide: Johns Hopkins antibiotic and infectious disease point-of-care guide; the closest specialty-direct competitor to Sanford Guide in antimicrobial therapy, sharing the same hospital, pharmacist, and ID-physician audience and content category.

Broad incumbents

• Medscape: WebMD Health's broad clinician reference and decision support platform offering free drug, disease, and guideline content; overlaps with Sanford Guide for the same clinician audience but competes on breadth and a free/ad-supported rather than subscription model.
• ClinicalKey: Elsevier's broad clinical decision support and reference platform covering dozens of specialties and licensed to institutions; overlaps with Sanford Guide in antimicrobial and pediatric content but is a much wider portfolio play targeting health system-wide reference budgets.

Emerging players

• OpenEvidence: AI-native clinical decision support tool that synthesizes medical literature into conversational answers for clinicians; an emerging disruptor whose LLM-based approach could substitute for traditional point-of-care references like Sanford Guide in specific use cases.
• VisualDx: Visual clinical decision support system used by clinicians for diagnosis and differential at the point of care; adjacent to Sanford Guide in clinician workflow and institutional licensing, with a differentiating visual/image-based approach.

Market position

Strengths1 record

Weaknesses4 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xtwitter.com/sanfordguide
• YouTubeyoutube.com/c/SanfordGuide-YouTube
• Facebookfacebook.com/SanfordGuide
• LinkedInlinkedin.com/company/sanfordguide
• Instagraminstagram.com/sanfordguide

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Sanford Guide