Name

Proteome Sciences

Legal name

Proteome Sciences plc

Website

https://proteomics.com

Company type

Public

Founded year

1994

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Product category

Proteomics Contract Research Services

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731), Laboratory Analytical Instruments (3826)

akta.pro primary industry

Proteomics & Mass Spectrometry Services (HLAGANAB)

akta.pro secondary industries

Mass Spectrometry & Spectroscopy Instruments (HLAGAIAB), Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation) (HLAAAIAI), DMPK / ADME & Bioanalysis (HLAGAFAC)

Keywords

• Proteomics services
• Protein biomarker discovery
• Mass spectrometry CRO
• Tandem mass tag reagents
• Clinical proteomics

Headquarters

HQ city

London

HQ country

United Kingdom

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. CRO Proteomics Services: Full suite of Mass Spectrometric based protein discovery and detection services offered on an outsourced client-driven basis. Services include Discovery Proteomics, Targeted Proteomics, Speciality Proteomics, and bioinformatics. Revenue generated through project-based contracts with biopharma clients.
2. TMT Reagent Sales: Manufacture and supply of TMT (Tandem Mass Tag) reagents - TMT 11-plex, TMTpro 18-plex and TMTpro 35-plex isobaric tags. Products sold exclusively through distribution partner ThermoFisher Scientific as part of their Mass Spectrometry consumable range.
3. GCLP Contract Services: Good Clinical Laboratory Practice compliant contract services for clinical trial sample analysis. The company secured two GCLP contracts worth over $1.5 million, with trial samples shipping in late Q1 2026.

Go-to-market motion2 records

Distribution channels2 records

Marketing channels7 records

Core offering

Proteome Sciences is a specialised Contract Research Organisation (CRO) offering a full suite of mass spectrometry-based protein discovery, validation and detection services on an outsourced client-driven basis. Its services span Discovery Proteomics (TMT LC-MS2/LC-MS3, SysQuant for PTMs, TMTcalibrator, Super Depletion), Targeted Proteomics (SRM/PRM, TMT-SRM) and Specialty Proteomics (Single Cell Proteomics, Peptidomics/MHC immunopeptidomics, IP Pull Down, Off-Gel Protein Sequencing, Protein Degrader/PROTAC assays), supported by computational proteomics and bioinformatics. The company also invented, developed and exclusively manufactures the proprietary TMT and TMTpro isobaric mass tag reagents (11-plex, 18-plex, 35-plex), which it sells globally through ThermoFisher Scientific.

Product overview

Proteome Sciences is a Contract Research Organisation (CRO) offering a full suite of mass spectrometry-based proteomic services. The core offering centers on their proprietary Tandem Mass Tag (TMT) technology platform, with TMT 11-plex, TMTpro 18-plex, and newly launched TMTpro 35-plex reagents sold exclusively through Thermo Scientific. Their service portfolio spans Discovery Based Proteomics (TMT LC-MS2 and LC-MS3 workflows), SysQuant for global phosphoproteomics, TMTcalibrator for tissue-enhanced fluid biomarker discovery, and Super Depletion for plasma/serum analysis. Targeted services include SRM/PRM assays and TMT-SRM for biomarker validation, plus specialty services such as Single Cell Proteomics (SysQuant SCP), Peptidomics, IP Pull Downs, Off-Gel Protein Sequencing, and Protein Degrader/PROTAC Assays. All services include comprehensive Computational Proteomics and Bioinformatics analysis using ML/AI tools for data interpretation.

Differentiator

Problem solved

Functional benefit

Products and services

• TMT (Tandem Mass Tags) Reagents Proprietary isobaric mass tagging reagents for multiplexed quantitative proteomics, including TMT 11-plex, TMTpro 18-plex and TMTpro 35-plex variants, sold as consumables to mass spectrometry laboratories worldwide via ThermoFisher Scientific.
• Discovery Based Proteomics Service Unbiased TMT-based mass spectrometry discovery service for detecting and quantifying thousands of proteins from fluid and tissue samples across multiple species; the umbrella service into which TMT LC-MS2, TMT LC-MS3 and the SysQuant workflows sit.
• TMT LC-MS3 Service High-accuracy quantitative proteomics workflow using TMT multiplexing with MS3 (SPS-MS3) fragmentation for enhanced precision, recommended for plasma biomarker discovery and complex samples.
• TMT LC-MS2 Service Standard quantitative proteomics workflow combining TMT multiplexing with LC-MS2 mass spectrometry for broad proteome coverage in cells and tissues.
• SysQuant Service (Global Phosphoproteomics) TMTpro-enabled workflow combining standard proteomic analysis with phospho- and other post-translational modification proteomics, simultaneously quantifying the proteome and specified PTMs (e.g. phosphorylation sites).
• TMTcalibrator Service Tissue-enhanced biomarker discovery workflow that combines fluids and tissues using TMT multiplexing to bias biomarker discovery toward disease-related proteins in peripheral fluids such as CSF and plasma.
• Super Depletion Service Advanced immunoaffinity depletion of highly-abundant proteins (Top-14 and Top-65) from plasma/serum, enabling detection of over 8,500 proteins in plasma/serum when combined with TMTcalibrator.
• SRM/PRM Targeted Assays Service Targeted mass spectrometry assays for absolute biomarker quantitation using Selected Reaction Monitoring (SRM) or Parallel Reaction Monitoring (PRM) for validation of 1 to 100+ protein targets.
• TMT-SRM Service Combined TMT and SRM workflow enabling rapid validation of biomarker candidates identified in TMT discovery workflows in a single multiplexed assay.
• SysQuant SCP (Single Cell Proteomics) Service Mass spectrometry-based single cell proteomics service detecting 1,000-1,500 proteins per individual cell using TMTpro reagents and extensive mass spectrometric analysis across 576 cells per run.
• Peptidomics Service Analysis of endogenously created protein fragments including MHC I/II immunopeptidomics for immune cell therapy, neoantigen identification and peptide vaccine development.
• IP Pull Down Service Immuno-precipitation sample pre-treatment service for specific protein enrichment, protein complex isolation and ultra-sensitive assays when commercial antibodies are unavailable.
• Off-Gel Protein Sequencing Service Gel-based protein identification service for analysis of proteins from SDS-PAGE bands or 2D gel spots, including biotherapeutic characterisation.
• Protein Degrader / PROTAC Assays Service Multi-level analytical service supporting targeted protein degradation drugs: proteomics for target confirmation, peptidomics for degradation fragments, and enrichment proteomics for monitoring ubiquitination.
• Computational Proteomics Service (AI/ML) Machine learning and AI-driven proteomics data analysis for biomarker discovery, pathway analysis and multi-omics integration to identify disease hallmarks and enable personalised treatment.
• Bioinformatics Package Service Comprehensive computational proteomics and bioinformatics analysis including data normalisation, exploratory analysis, linear modelling and functional enrichment.
• GCLP-Compliant Clinical Targeted Assay Service Good Clinical Laboratory Practice (GCLP) compliant targeted proteomics assays run at the Frankfurt facility for clinical trial sample analysis, including the target engagement/chemoproteomics clinical contract.

Quantifiable outcome

• Detects >8,500 proteins in plasma/serum
• +4 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability3 records

Feature7 records

Partnerships

One partnership is on record.

• ThermoFisher ScientificcoreChannel Partner/ Reseller/ DistributorExclusive distribution partnership where ThermoFisher Scientific sells TMT and TMTpro reagents as part of their Mass Spectrometry consumable range globally. Proteome Sciences manufactures all TMT products in their Frankfurt laboratory while ThermoFisher handles global distribution and sales.

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Emerging players

• Seer: Proteomics platform company developing nanoparticle-based deep proteome profiling. Competes conceptually in deep plasma/serum proteomics, overlapping with Proteome Sciences' TMTcalibrator and Super Depletion workflows.
• Nautilus Biotechnology: Emerging single-molecule proteomics platform company pursuing large-scale proteome quantification. Partial overlap with Proteome Sciences' SysQuant SCP single-cell proteomics service and adjacent to the broader proteomics market.

Broad incumbents

• Eurofins Scientific: Global laboratory services group offering a wide range of bioanalytical and proteomics testing services. Adjacent competitor via breadth rather than proteomics specialization.
• Charles River Laboratories: Large CRO with extensive drug-discovery and preclinical services, including proteomics/biomarker capabilities within a much broader portfolio. Competes for the same biopharma budget as Proteome Sciences but at much greater scale.
• LabCorp (Covance): Major clinical and bioanalytical laboratory services provider with central lab and biomarker capabilities used by biopharma across clinical trials. Competes for clinical trial sample analysis work that Proteome Sciences targets through its GCLP service.

Direct peers

• Caprion Biosciences: Specialized proteomics and immune monitoring CRO offering biomarker discovery and validation services to biopharma. Comparable business model and customer base to Proteome Sciences.
• Cell Signaling Technology (CST): US-based proteomics reagents and assay developer with strong antibody and immunoassay portfolio serving the same academic and biopharma research market. Overlaps with Proteome Sciences' targeted assay offering.
• Reaction Biology: CRO offering mass spectrometry-based drug discovery services including protein characterization and target engagement assays. Comparable niche CRO positioning with biopharma clients.
• Biognosys: Swiss contract research organisation specializing in mass spectrometry-based proteomics services (TrueDiscovery, TrueTarget, TrueSignature). Closest functional peer to Proteome Sciences' discovery and targeted proteomics CRO offering.
• Olink (Standard BioTools): Swedish proteomics tools company offering proximity-extension assay-based protein biomarker reagents and services. Directly comparable as a proteomics-focused vendor selling into biopharma discovery and clinical research.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/proteomescience
• LinkedInlinkedin.com/company/proteome-sciences-plc

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Subsidiaries2 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Proteome Sciences