Naturalendo Tech

What Naturalendo Tech does

Naturalendo Tech (주식회사 내츄럴엔도텍) is a Seongnam, South Korea-headquartered, KOSDAQ-listed biotechnology company (IPO October 2013) founded in May 2001 that develops proprietary botanical bioactive ingredients for health functional foods and functional cosmetics. Its technology base, anchored by the corporate-affiliated Herbal Hormone Research Institute established 2001, centers on patented phytochemical formulations — most notably EstroG-100® (a Cynanchi Wilfordii Radix / Phlomis Umbrosa Turczaninow / Angelica Gigas blend that is the first KFDA-approved functional ingredient for women's menopause), HabaNova™ (non-spicy capsinoid body fat ingredient from the exclusive SNU WONDER HO chili variety, Plant Variety Protection No. 8991, protected through 2042), NET 2401 insomnia formulation, Q.186 male menopause complex, NET 1701 prostate health, YGF 251 height growth, Stauntonia hexaphylla anti-inflammatory, and the world's-first micro-needle patch using cross-linked hyaluronic acid. The portfolio comprises 22 Korean and 20 international patents.

The company operates a dual B2B/B2C revenue model. On the B2B side it licenses and exports proprietary ingredient formulations and OEM/ODM contract-manufactured extracts to global pharmaceutical, supplement, and cosmetic companies in 52 countries — anchor partners include STADA (Germany), DM Drogerie Markt (Germany), Unilever/OLLY (USA, Mellow Menopause), Geneian Pharmed (Iran), Somar (Mexico), Aim Global (Philippines), Walgreens/CVS (USA), Douglas/Flaconi (Germany), and Curato (India). On the B2C side it sells finished branded products through NEEDLY (a low-irritation clean-beauty skincare brand whose Daily Toner Pad surpassed 1 million cumulative units as of April 2024) and NEEDIN (an inner-beauty enzyme supplement brand), distributed in Korea via Olive Young, LALAVLA, Market Kurly, MiniStop, CHICOR, Naver Smart Store, and brand e-commerce, and internationally through Olive Young Global (150+ countries), home-shopping channels (EVINE, HSE24, Zhejiang TV), and reverse-import channels.

Manufacturing is vertically integrated through two certified Korean facilities: a 33,058 m² GMP/HACCP/FSSC 22000-certified health supplement plant in Icheon (operational since August 2014; FSSC 22000 acquired June 2025) and a 1,818 m² CGMP/ISO-certified cosmetics and micro-needle patch plant in Osong, both reinforcing the OEM/ODM offering. EstroG-100® holds hard-to-replicate regulatory approvals across KFDA (April 2010), U.S. FDA NDI (October 2010), Health Canada NPN (July 2011), and EU EFSA Novel Food (August 2018), and additional registrations have been secured for microneedle patches (Japan cosmetics August 2016, China CFDA May 2017, Malaysia HALAL October 2017). China operations run through a wholly-owned subsidiary, Beijing Biochemistry Co., Ltd. (北京生化化學有限公司), established February 2015. The company is led by CEO Kim Hee-do (김희도).

Name

Naturalendo Tech

Legal name

(주) 내츄럴엔도텍

Website

https://naturalendo.co.kr

Company type

Public

Founded year

2001

Operating status

Operating

Short description

Naturalendo Tech (주식회사 내츄럴엔도텍) is a KOSDAQ-listed Korean biotech (founded 2001) that develops patented botanical ingredients — most prominently EstroG-100® for women's menopause — licensing them in 52 countries while selling NEEDLY skincare and NEEDIN inner-beauty supplements direct-to-consumer in Korea and internationally.

Ownership category

akta.pro rank

Product category

Botanical Health Supplements & Clean Beauty

NAICS

Medicinal and Botanical Manufacturing (325411), Food (Health) Supplement Retailers (456191)

SIC

Medicinal Chemicals & Botanical Products (2833), Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro primary industry

Herbal & Botanical Supplements (CRADAGAD)

akta.pro secondary industries

Condition-Specific Bioactives (Glucosamine/Chondroitin, Plant Sterols, Melatonin, Lutein/Zeaxanthin) (AFAJAKAK), Personal Care & Cosmetic Ingredients (IMAEABAJ), Botanical/Herbal & Adaptogen Functional Beverage Production (AFAFAFAF), Healthy Aging & Cognitive Support Supplements (CRADAGAM), Functional Foods & Wellness Beverage Retail (Kombucha, Adaptogens, CBD where legal) (CRAHAEAH)

Keywords

• Botanical health ingredients
• Menopause dietary supplements
• Clean beauty skincare
• Functional food extracts
• Cosmetic microneedle patches

Headquarters

HQ city

Seongnam

HQ country

South Korea

HQ region

Asia

Offices4 records

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Proprietary Ingredient Licensing & Export (B2B): Licensing and exporting proprietary botanical ingredient formulations (EstroG-100®, HabaNova™, NET 2401, Q.186, NET 1701, etc.) to global health supplement and cosmetic brands and distributors. Products sold as raw materials or licensed formulations to international partners including STADA, DM, Unilever/Olly, Geneian Pharmed, Somar, and others across 52 countries.
2. Consumer Brand Sales (B2C): Direct-to-consumer sales of finished products under proprietary brands NEEDLY (skincare/clean beauty) and NEEDIN (inner beauty dietary supplements) through e-commerce channels (official mall, Naver Smart Store) and retail distribution (Olive Young, LALAVLA, Market Kurly, convenience stores).
3. Contract Manufacturing (OEM/ODM): Manufacturing and supplying high-quality botanical extract raw materials to global partners, including GMP-certified liquid extract products, powder extract products, and powder processed goods from Icheon factory.

Go-to-market motion3 records

Distribution channels7 records

Marketing channels8 records

Core offering

Naturalendo Tech researches, develops, and manufactures proprietary botanical ingredient formulations (such as EstroG-100®, HabaNova™, NET 2401, Q.186, and YGF 251) for women's health, sleep, weight management, anti-inflammation, and men's health applications. It sells these ingredients B2B to global health supplement and cosmetic brands across 52 countries, while also selling finished consumer products directly through its NEEDLY skincare and NEEDIN inner beauty supplement brands via Korean retail and e-commerce channels.

Product overview

Naturalendo Tech is a health and beauty company specializing in natural bioactive material research and development. The company operates two main business areas: Health (health functional food ingredients and supplements) and Beauty (cosmetics and skincare products). The health segment centers on patented natural ingredient formulations including EstroG-100® for women's menopause, HabaNova™ for weight management, YGF 251 for height growth, NET 2401 for sleep improvement, Stauntonia hexaphylla for anti-inflammation, Q.186 for male menopause, NET 1701 for prostate health, and Quercus Acuta Thunb extract for skin anti-aging. The beauty segment operates through two sub-brands: NEEDLY (clean beauty skincare featuring pad products like Daily Toner Pad and Anti Trouble Pad) and NEEDIN (inner beauty supplements including enzyme powders and diet products). The company exports to 52 countries worldwide and operates GMP-certified manufacturing facilities in Icheon and Osong, Korea.

Differentiator

Problem solved

Functional benefit

Brands

• NEEDLY: A low-irritation skincare brand offering clean beauty products including Daily Toner Pad, Anti Trouble Pad, Mild Cleansing Gel, and Mild Enzyme Cleansing Powder. Slogan: 'For what's needed, just the right amount.'
• NEEDIN

Products and services

• EstroG-100® Patented phytoestrogen blend of Cynanchi Wilfordii Radix, Phlomis Umbrosa Turczaninow, and Angelica Gigas that improves 10 menopausal symptoms without affecting estrogen levels (E2, FSH) or binding to estrogen receptors. Licensed globally to supplement and pharma brands.
• HabaNova™ Non-spicy chili variety developed through crossbreeding from 653 genetic resources, delivering capsinoid health benefits (capsiate 384.91 mg/kg) for body fat reduction without the pungency or digestive irritation of capsaicin. Activates UCP1 for fat burning.
• NET 2401 Patented insomnia improvement formulation featuring Phlomis Umbrosa Turczaninow and HerbEx Polygala Extract. Clinically shown to increase adenosine A1 receptors by 280% and melatonin levels by 43%, reducing sleep latency by 22% and increasing sleep duration by 50%.
• NET 1701 Patented male prostate health formulation that inhibits 5α-reductase to prevent prostate enlargement while increasing testosterone without sexual function-related side effects.
• Q.186 Complex Patented male menopause improvement formulation containing Elaeagnus Multiflora Thunb and Cynanchi Wilfordii Radix Water Extract. Clinically proven to increase testosterone by 278% and reduce AMS scores by 32.5% in men aged 45-75.
• YGF 251 Patented height growth promoter containing Phlomis Umbrosa Turczaninow and Commelina Communis Extract. Increases IGF-1 production and stimulates femoral bone length growth by approximately 6%.
• Stauntonia hexaphylla Fruit Extract Patented anti-inflammatory ingredient selected from over 100 native plant species. Inhibits multiple inflammatory substances (NO, PGE2, COX-2, TNF-α, IL-1β, IL-6) and reduces foot edema inflammation.
• Quercus Acuta Thunb Fruit Extract (UVerry™) Patented UV-induced skin aging prevention cosmetic ingredient. Blocks multiple photoaging pathways, increases collagen production by 143%, and inhibits elastase by 72%.
• NEEDLY Skincare Brand Clean beauty skincare brand offering low-irritation products with reliable clean formulas and eco-friendly minimal packaging. Key products include Daily Toner Pad, Anti Trouble Pad, Mild Cleansing Gel, Mild Enzyme Cleansing Powder, and Mild Micellar Cleansing Water. Sold through Korean retail (Olive Young, LALAVLA, CHICOR) and e-commerce.
• NEEDIN Inner Beauty Brand Inner beauty dietary supplement brand offering enzyme powders (Bium Enzyme, Guma Enzyme) and diet supplements (Haru Diet Burning, Bium Diet Clean). Sold through Korean H&B retail (Olive Young, Market Kurly, MiniStop convenience stores) and e-commerce.
• NEEDLY Daily Toner Pad (데일리 토너 패드) Daily moisturizing pad with 80mm diameter and 280g high-volume essence containing BHA and PHA for gentle daily exfoliation. Completed 4-fold pore improvement human application test. Vegan-certified, low-irritation formula.
• NEEDLY Anti Trouble Pad (안티 트러블 패드) Trouble care pad containing 4 types of peeling ingredients (AHA, BHA, PHA, LHA) and DERMATIC AC 3 patented ingredient. Vegan certified, 100% biodegradable material, completed sensitive skin and acne-prone skin tests.
• NEEDLY Mild Cleansing Foam (마일드 클렌징폼) Gentle cleansing foam with 'mochi' foam texture using upcycled oat meal. Contains moisturizing ingredients while maintaining strong cleansing power for makeup and sunscreen removal.
• NEEDLY Glow Peeling Serum (글로우 필링 세럼)

Quantifiable outcome

• KMI (Kupperman Menopause Index) improved by 62% with EstroG-100® use
• +9 more outcomes

Named customers11 records

Segments4 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature9 records

Partnerships

15 partnerships are on record, tiered core, flagship, minor and major.

• Chonnam National University Industry-Academia Cooperation Foundation (전남대학교 산학협력단)coreStrategic or Co-development Partner · 1 June 2025Collaborating as lead research institution on the Ministry of Agriculture's 2 billion KRW 'Food Microbiome Enzyme Resource Technology Development' project (April 2024 – December 2028), together with 4 other institutions. Focus on domestic enzyme development to replace imported enzymes from Novozyme (Denmark), DuPont (USA), and DSM (Netherlands).
• Ministry of Agriculture, Food and Rural Affairs (MAFRA) – Agri-Bio Microbiome Innovation Technology ProjectcoreOthers · 1 April 2025Selected for the 'Agri-Bio Microbiome Innovation Technology Project' led by MAFRA. Total research budget of 2 billion KRW over April 2024 to December 2028. Research focuses on enzyme resource utilization technology for food microbiome, collaborating with Chonnam National University and 4 other institutions.
• Unilever / OLLY (United States)flagshipGTM or Marketing Partner · 1 August 2024Naturalendo Tech partnered with Unilever's health supplement subsidiary OLLY to launch 'Mellow Menopause' in the US market. The product combines Naturalendo's proprietary EstroG-100® with GABA for comprehensive menopause symptom relief. OLLY is a San Francisco-based health functional food brand established in 2013, known for its appealing product formulations and sensory packaging design.
• Ministry of SMEs and Startups (MSS) – SME Technology Development Support ProjectminorOthers · 1 July 2023Selected for the 'SME Technology Development Support – Purchase-Conditioned New Product Development Project' in July 2023.
• Korea Forest Service – Forest Biomaterials Utilization Technology Development ProjectminorOthers · 1 April 2023Selected for the Korea Forest Service's 'Forest Biomaterials Utilization Technology Development Project' in April 2023.
• Seoul National University Industry-Academia Cooperation Foundation (South Korea)coreStrategic or Co-development Partner · 1 November 2022Signed technology transfer agreement for HabaNova™ (body fat reduction ingredient) developed through a joint breeding program. The agreement covers the exclusive use of the SNU WONDER HO chili variety (Plant Variety Protection No. 8991) for the HabaNova™ product. HabaNova™ was developed by selecting from 653 chili genetic resources and crossbreeding with habanero peppers.
• Jeonnam Bio Foundation (전남바이오진흥원, South Korea)coreStrategic or Co-development Partner · 1 March 2021Multiple technology transfer agreements signed: (1) March 2017 - next-generation women's health improvement ingredient; (2) October 2019 - male menopause symptom improvement ingredient (Q.186); (3) March 2022 - UVerry™ anti-wrinkle cosmetic ingredient (Quercus Acuta Thunb extract); (4) October 2024 - cognitive improvement ingredient.
• Douglas & Flaconi (Germany)majorChannel Partner/ Reseller/ Distributor · 1 August 2019Microneedle patches launched through German premium beauty retailers Douglas and Flaconi in August 2019.
• Aim Global (Philippines)majorChannel Partner/ Reseller/ Distributor · 1 June 2019Angel-E women's menopause product launched with Philippine direct sales company Aim Global in June 2019.
• DM Drogerie Markt (Germany)majorChannel Partner/ Reseller/ Distributor · 1 February 2019Women's menopause product supply contract signed in February 2019 for distribution through DM drugstore chain in Germany.
• Somar (Mexico)majorChannel Partner/ Reseller/ Distributor · 1 September 2018Microneedle patch supply contract signed with Mexican pharmaceutical company Somar in September 2018.
• Curato (India)majorChannel Partner/ Reseller/ Distributor · 1 June 2018Microneedle patches launched by Curato, a dermatology-focused pharmaceutical company in India, in August 2018.
• Geneian Pharmed (Iran)majorChannel Partner/ Reseller/ Distributor · 1 February 2016EstroG-100® registered with Iranian pharmaceutical company Geneian Pharmed in February 2016, marking the first registration in the Middle East. Expanded to additional Middle East and Africa countries including Egypt.
• STADA Arzneimittel AG (Germany)coreChannel Partner/ Reseller/ Distributor · 1 December 2015Contract signed in December 2015 for EstroG-100® licensing and distribution in European markets. STADA is a German pharmaceutical company distributing health supplements across Europe.
• Egyptian Pharmaceutical CompanymajorChannel Partner/ Reseller/ Distributor · 1 December 2015EstroG-100® product launched by Egyptian pharmaceutical company in November 2023. Contract also covered 12 additional Middle East and Africa countries.

Scale indicators5 records

Recent moves8 records

Expansion highlights7 records

Broad incumbents

• Givaudan (Naturex): Swiss global leader in flavors and fragrances with significant botanical extracts and natural ingredients business via Naturex. Competes with Naturalendo Tech in plant-derived nutraceutical and cosmetic ingredient supply.
• Innisfree: Korean clean beauty brand under Amorepacific with botanical/natural positioning. Comparable as a Korean botanical-focused skincare brand with global retail distribution.
• Symrise: German-based global supplier of flavors, fragrances, and natural ingredients including plant-based extracts for food, supplement, and cosmetic applications. Comparable B2B ingredient model.
• Kolmar Korea: Major Korean cosmetics and health functional food contract manufacturer with global brand partners. Comparable in GMP-certified manufacturing capabilities and B2B/B2C hybrid model.
• IFF (International Flavors & Fragrances): US-listed global ingredient powerhouse with health, biosciences, and scent divisions including botanical extracts. Competes in the global B2B specialty ingredient supply market.
• Amorepacific: Korea's largest cosmetics group with herb/botanical-based skincare (Sulwhasoo, Innisfree) and supplements. Comparable as a Korean incumbent combining botanical R&D with global brand distribution.

Direct peers

• Indena: Italian producer of botanical active ingredients for pharmaceutical, nutraceutical, and personal care markets. Directly comparable as a vertically integrated botanical extract specialist with patented ingredients.
• COSRX: Korean clean beauty skincare brand with strong Olive Young and global e-commerce presence. Directly comparable NEEDLY competitor in low-irritation skincare category.
• Sabinsa: US-based manufacturer of patented branded botanical extracts and nutraceutical ingredients for B2B licensing. Closely comparable business model to Naturalendo Tech's proprietary ingredient licensing model.

Regional players

• Kwang Dong Pharmaceutical: Korean pharmaceutical company with health functional food and herbal product portfolio. Comparable as a Korean herbal/botanical health supplement player.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/naturalendo-tech-co-ltd-

Compliance10 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Naturalendo Tech