Pain Institute of Southern Arizona

What Pain Institute of Southern Arizona does

Pain Institute of Southern Arizona (PISA) is a privately-held interventional pain management medical practice founded in 2004 and headquartered in Tucson, Arizona. It operates five clinic locations - three in Tucson and two Regional Pain Institute (RPI) locations in Queen Creek/San Tan Valley and Apache Junction - delivering minimally invasive procedures such as spinal cord stimulation, basivertebral nerve ablation (Intracept), peripheral nerve and spinal cord neuromodulation (Nalu, Saluda Evoke closed-loop system), radiofrequency ablation, epidural steroid injections, facet joint injections, kyphoplasty, and the MILD minimally invasive lumbar decompression procedure, alongside medication management and durable medical equipment dispensing. It employs approximately 8 fellowship-trained interventional pain physicians (with credentials from Mayo Clinic, Stanford, Harvard, Johns Hopkins, and other top institutions) plus multiple advanced practice providers, and treats chronic pain patients primarily through physician referrals, insurance billing, and limited self-referral.

Revenue is generated from two streams: professional services billed to insurance for patient consultations, diagnostic evaluations, and interventional procedures, and durable medical equipment sales covering spinal braces, knee unloader braces, cervical collars, and wrist supports. Distribution is direct-to-patient through scheduled appointments at clinic locations, supported by a multi-channel marketing approach that combines local TV media appearances, provider-led webinars, community presentations, an annual CME conference on Pain Management, and a substantial patient-review system. The practice maintains clinical partnerships and sponsorships with major neuromodulation device vendors including Saluda Medical, Abbott, Nalu Medical, Boston Scientific, Medtronic, Vertos, Sprint/SPR, Lucid Lane, and Nevro, and holds a new partnership with Banner Surgery Center - Fort Lowell for outpatient surgical access.

In 2025, PISA consolidated its footprint by closing its Benson Clinic and integrating the Regional Pain Institute, while continuing physician and APP hiring. Key leadership includes Dr. Eric Cornidez (Stanford-trained, Executive MBA, Mayo fellowship) as Chief Medical Officer and Managing Partner, and Dr. Efrain Cubillo (Harvard fellowship, Mayo anesthesia residency) as Managing Partner. The practice competes on talent credentials, brand recognition earned over 20 years, and adoption of emerging FDA-cleared neuromodulation devices, and is described in its own materials as the largest and most respected pain management center in Southern Arizona.

Name

Pain Institute of Southern Arizona

Legal name

Pain Institute of Southern Arizona

Website

https://pisapain.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

101–250 employees

Short description

Pain Institute of Southern Arizona is a private interventional pain management medical practice serving chronic pain patients across Southern Arizona through five clinic locations, with fellowship-trained physicians delivering spinal cord stimulation, the Intracept procedure, Nalu neurostimulation, and related minimally invasive therapies.

Ownership category

akta.pro rank

Product category

Pain Management Services

NAICS

Offices of Physical, Occupational and Speech Therapists, and Audiologists (621340)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Specialty Outpatient Facilities, Nec (8093), Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842)

akta.pro primary industry

Pain Management Clinics (Interventional & Medical) (HLAFABAH)

akta.pro secondary industry

Pain Management & Interventional Procedure Centers (HLAFAIAH)

Keywords

• Interventional pain management
• Chronic pain treatment
• Spinal cord stimulation
• Pain management procedures
• Durable medical equipment

Headquarters

HQ city

Tucson

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Supply Chain, Marketing or Sales, Technology or R&D

Revenue model

1. Patient Clinical Services: Revenue generated from patient consultations, diagnostic evaluations, interventional procedures, and ongoing pain management treatments. Services include epidural steroid injections, nerve blocks, radiofrequency ablation, spinal cord stimulation, joint injections, and other interventional pain procedures. The practice accepts insurance and processes claims through health plans.
2. Durable Medical Equipment (DME): Sale and dispensing of durable medical equipment including spinal braces (LSO, TLSO), knee unloader braces, cervical collars, and wrist supports for pain management and post-procedure support.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels8 records

Core offering

Pain Institute of Southern Arizona (PISA) is a specialized interventional pain management medical practice that diagnoses and treats chronic pain conditions through minimally invasive procedures. The practice offers a comprehensive suite of services including spinal cord stimulation, radiofrequency ablation, epidural steroid injections, joint injections, the Intracept procedure for vertebrogenic low back pain, the Nalu Neurostimulation System, and the MILD procedure for lumbar spinal stenosis. PISA also dispenses durable medical equipment such as spinal braces, knee unloader braces, and cervical collars.

Product overview

Pain Institute of Southern Arizona (PISA) is a specialized interventional pain management medical practice, not a software product company. The organization operates as a network of pain management clinics offering a comprehensive suite of medical treatments and procedures. The core offerings include interventional pain procedures (epidural injections, radiofrequency ablation, spinal cord stimulation), specialized minimally invasive treatments (Intracept Procedure for vertebrogenic pain, Nalu Neurostimulation System for chronic pain), and Durable Medical Equipment (DME) including braces and orthotic devices. The practice serves patients throughout Southern Arizona with multiple clinic locations.

Differentiator

Problem solved

Functional benefit

Products and services

• Intracept® Procedure A minimally invasive, implant-free outpatient procedure that relieves vertebrogenic chronic low back pain by heating the basivertebral nerve (BVN) with a radiofrequency probe to stop pain signals from reaching the brain. The procedure is FDA-cleared, same-day, and provides pain relief lasting more than 5 years after a single treatment. It is offered to patients with chronic vertebrogenic low back pain who have failed conservative treatments.
• Nalu Neurostimulation System A novel micro-IPG (implantable pulse generator) system used for Peripheral Nerve Stimulation (PNS) and Spinal Cord Stimulation (SCS) to manage chronic intractable pain. It features an external battery/wearable Therapy Disc with an FDA-cleared minimum 18-year service life, smartphone control via iPhone/Android app, minimally invasive implantation, and a trial period before permanent implant. Offered to patients with chronic intractable pain.
• Durable Medical Equipment (DME) Prescription medical equipment including lumbar support braces (LSO Revel Plus, Trend TLSO), knee unloader braces, cervical therapy collars, and wrist immobilization devices sold and dispensed by the practice for pain management and post-procedure support.
• Pain Management Procedures Comprehensive interventional pain management procedures including epidural steroid injections, facet joint injections, radiofrequency ablation (including Saluda Evoke closed-loop spinal cord stimulation), kyphoplasty, trigger point injections, joint injections, and other minimally invasive treatments offered to patients with chronic pain conditions.

Quantifiable outcome

• 5-year sustained pain relief after single Intracept treatment
• +1 more outcomes

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Six partnerships are on record, tiered core.

• Saluda MedicalcoreTechnology or Integration · 1 January 2025Platinum Breakfast Sponsor of PISA 2025 CME Conference. Provider of the Evoke Spinal Cord Stimulation System which PISA offers to chronic pain patients.
• AbbottcoreTechnology or Integration · 1 January 2025Gold Sponsor of PISA 2025 CME Conference. Abbott provides neuromodulation and spinal cord stimulation technologies.
• Nalu MedicalcoreTechnology or Integration · 1 January 2025Silver Sponsor of PISA 2025 CME Conference. Provider of the Nalu Neurostimulation System for PNS and SCS that PISA offers to chronic pain patients.
• Boston ScientificcoreTechnology or Integration · 1 January 2025Silver Sponsor of PISA 2025 CME Conference. Medical device company providing pain management technologies.
• MedtroniccoreTechnology or Integration · 1 January 2023Gold Sponsor of PISA 2023 CME Conference. Major medical device company providing pain management technologies.
• Banner Surgery Center - Fort LowellcoreStrategic or Co-development PartnerNew partnership announced with Banner Surgery Centers. The surgical center formerly operated under a different name has been rebranded as Banner Surgery Center - Fort Lowell, providing surgical facility access for PISA patients requiring interventional pain procedures.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Cleveland Clinic Pain Management Center: Academic medical center-based pain management program offering comprehensive interventional pain services within a large integrated delivery system; comparable procedure mix and patient population at scale.
• Clearway Pain Solutions: PE-backed national pain management platform consolidating multi-site pain practices; competes directly for physicians and patients in regional markets using similar procedural offerings.
• Mayo Clinic Pain Clinic: Academic pain medicine program within Mayo Clinic offering interventional pain therapies; comparable in clinical sophistication and overlaps with several PISA physicians' training pedigree.

Emerging players

• Saluda Medical: Manufacturer of the Evoke closed-loop spinal cord stimulation system used at PISA; platinum sponsor of PISA's CME conference and strategically aligned in driving SCS adoption.
• PainTEQ: Medical device company behind the mild® Minimally Invasive Lumbar Decompression procedure that PISA offers; close ecosystem partner with aligned commercial interest in expanding the procedure's adoption.
• Relievant Medsystems: Developer of the Intracept Procedure for vertebrogenic low back pain, a flagship PISA offering; close commercial relationship and shared growth interest in BVN ablation adoption.

Direct peers

• Arizona Pain Specialists: Phoenix-metro based interventional pain management practice serving the Arizona market — directly competitive in geography and overlapping in service offerings.
• US Pain & Spine Centers: Multi-state interventional pain management group offering SCS, RFA, injections, and other minimally invasive pain procedures — directly comparable in service mix and growth-by-acquisition strategy.
• Texas Pain Relief Group: Multi-location interventional pain practice offering epidural steroid injections, facet injections, RFA, spinal cord stimulation, and other procedures — comparable procedural portfolio to PISA.
• National Spine & Pain Centers: One of the largest interventional pain management practices in the U.S., operating multi-site clinics across multiple states with a similar mix of epidural injections, RFA, spinal cord stimulation, and other interventional procedures.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/PainInstituteAZ
• Facebookfacebook.com/pisapain

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pain Institute of Southern Arizona