What Polypure does

Polypure AS is a Norwegian specialty chemical manufacturer founded in 1999 and headquartered in Fornebu (Oslo), Norway, producing high-purity monodisperse polyethylene glycol (PEG) and polypropylene glycol (PPG) oligomers and derivatives for pharmaceutical, biotechnology, and nanotechnology customers. The company's core technology is a proprietary Simulated Moving Bed Chromatography (SDC) purification platform developed by founder and CEO Erik Agner, which fractionates polydisperse polymer blends into single-length oligomer species at >99% purity for PEG and >98% for PPG — protected in part by US Patent No. 6,576,134. The product catalog spans PEG diols (PEG-7 to PEG-45), mPEGs, PEG azides and amines, amino PEG acids, PEG esters and acids, PEG thiols and disulfides, and special reagents (biotin-PEGs, maleimide/NHS-ester heterobifunctionals), with a newly launched monodisperse PPG line for thermoresponsive drug delivery.

Polypure operates a sales-led B2B model: products are sold directly from its Norwegian headquarters through email inquiry ([email protected], [email protected]) and phone (+47 21 08 07 40), with no resellers or distribution intermediaries. Pricing is in EUR on a per-gram or per-multi-gram basis, ranging from approximately 125 EUR (1 g of low-MW PEG diol) to 2,025 EUR (5 g of mPEG-44 amine), with volume discounts available for larger quantities. Revenue is generated through two streams: (1) catalog sales of off-the-shelf monodisperse PEG derivatives in gram to multi-kilogram quantities, and (2) custom synthesis services for clients with specialized requirements. Customers are concentrated in pharmaceutical drug development (PEGylation of peptides, lipid nanoparticles for vaccines including mRNA LNPs, drug delivery) with biotech and academic research as secondary segments; Polypure's PEG derivatives are used from early research through clinical trials and into approved drugs on market.

The company is founder-led and privately held with no disclosed external funding. Its roughly 12-person team includes a CEO, CTO, Director of Commercial Development, Sales Manager, production engineers, R&D scientists, and a senior technical development engineer. Strategic positioning emphasizes participation in three EU-funded research consortia (PAVE, NOVA-MRI, PIANO), attendance at CPHI Frankfurt 2025, an academic Ph.D. pipeline with University of Stavanger, and continuous product portfolio expansion including a 5 kDa PEG line and the first-ever monodisperse PPG offering.

Name

Polypure

Legal name

Polypure AS

Website

https://polypure.com

Company type

Private

Founded year

1999

Operating status

Operating

Headcount range

1–10 employees

Short description

Polypure AS is a Norwegian specialty chemical manufacturer founded in 1999 that produces high-purity monodisperse PEG and PPG oligomers via proprietary SDC chromatography for pharmaceutical, biotech, and nanotechnology customers, selling catalog derivatives and custom synthesis services on a direct B2B basis.

Ownership category

akta.pro rank

Product category

Specialty Chemicals (Pharmaceutical Excipients)

NAICS

Plastics Material and Resin Manufacturing (325211)

SIC

Plastic Materials, Synth Resins & Nonvulcan Elastomers (2821), Industrial Organic Chemicals (2860)

akta.pro primary industry

Polymer Compounds & Masterbatches (Compounding, Color/Fill/Additive Concentrates) (IMAEANAJ)

Keywords

• Monodisperse PEG oligomers
• Polyethylene glycol derivatives
• Pharmaceutical excipients
• PEGylation reagents
• Bioconjugation linkers

Headquarters

HQ city

Oslo

HQ country

Norway

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Supply Chain, Marketing or Sales, Infrastructure

Revenue model

1. Monodisperse PEG Product Sales: Sale of catalog monodisperse PEG derivatives including PEG-45, mPEG variants, PEG azides, amines, esters, acids, thiols, and special reagents. Products are sold in gram to multi-kilogram quantities with pricing ranging from approximately 125 EUR (1g) to several thousand EUR (5g) depending on molecular weight and complexity.
2. Custom Synthesis Services: Custom synthesis and production of high-purity materials for clients with specialized requirements. The company has expertise to provide customized products and services for clients seeking specialized solutions in multi-kilo quantities.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Polypure synthesizes, purifies, and delivers high-purity monodisperse polyethylene glycol (PEG) and polypropylene glycol (PPG) oligomers and their functionalized derivatives. Products are sold in gram to multi-kilogram quantities to pharmaceutical, biotech, and nanotech customers for applications including PEGylation, drug delivery, lipid nanoparticles for vaccines, and bioconjugation. Custom synthesis services are offered in parallel with the catalog range.

Product overview

Polypure is a Norwegian chemical manufacturing company founded in 1999 specializing in high-purity, monodisperse polyethylene glycol (PEG) and polypropylene glycol (PPG) oligomers and derivatives for pharmaceutical, biotech, and nanotech applications. The product portfolio comprises multiple product lines including: PEG 2kDa products (PEG-45, mPEG-45, mPEG-44 amine, mPEG-45 propionic acid, mPEG-44 thiol, PEG-43 diamine); PEG 5kDa products (Azido PEG-116, mPEG-117, mPEG-116 amine, Azido PEG-106 amine); general PEG diols (PEG-8, PEG-12, PEG-28); mPEGs (mPEG-11, mPEG-45 diol); PEG azides & amines (Azido PEG-7 amine, Azido PEG-22 amine, Azido PEG-44, PEG-26 diamine, PEG-43 diamine, Boc amino PEG-6 amine, Boc amino PEG-10 amine); amino PEG acids (Amino PEG-23 acid, Amino PEG-35 acid); PEG esters & acids (mPEG-11 propionic acid, mPEG-45 propionic acid, PEG-12 diacid, PEG-7 thiol acid, PEG-29 thiol acid, Azido PEG-7 diglycolic acid, Boc-amino PEG-27 propionic acid, Fmoc-amino PEG-11/23/27 propionic acid, PEG-12 tBu-propionate); PEG thiols & disulfides (PEG-7 thiol, mPEG-6 thiol, mPEG-44 thiol, mPEG-6 disulfide, PEG-7 acid disulfide, PEG-7 NHS ester disulfide); and special reagents (Biotin PEG-8 amine, Biotin PEG-11 propionic acid, Biotin PEG-10 thiol, Maleimidopropionyl PEG-27 NHS ester, Pyr-S-S-PEG-29 NHS ester). The company also developed a new monodisperse PPG product line for thermoresponsive drug delivery applications. Custom synthesis services are available for specialized requirements.

Differentiator

Problem solved

Functional benefit

Products and services

• Monodisperse PEG 2 kDa Product Line Monodisperse polyethylene glycol products with approximately 2 kDa molecular weight (around 45 ethylene glycol units) including PEG-45, mPEG-45, mPEG-44 amine, mPEG-45 propionic acid, mPEG-44 thiol, mPEG-45 diol, Azido PEG-44, and PEG-43 diamine. Sold to pharmaceutical, biotech, and nanotech customers for PEGylation of biomolecules and as 2 kDa PEG linkers.
• Monodisperse PEG 5 kDa Product Line
• PEG Diols Monodisperse PEG diol products including PEG-8 (MW 370.4), PEG-12 (MW 546.7), and PEG-28 (MW 1251.5). Bifunctional PEGs with terminal hydroxyl groups used as linkers and spacers in chemical synthesis and pharmaceutical applications.
• Monomethoxypolyethylene Glycol (mPEG) Products Monodisperse methoxypolyethylene glycol (mPEG) products including mPEG-11 (MW 516.6) and mPEG-45 (MW 2014.4). Monofunctional PEGs used for PEGylation of therapeutics.
• PEG Azides and Amines Monodisperse PEG derivatives with azide and amine functional groups for click chemistry, bioconjugation, peptide synthesis, and crosslinking applications. Includes heterobifunctional and homobifunctional variants.
• Amino PEG Acids Monodisperse bifunctional PEG derivatives carrying both an amine and a carboxylic acid, including Amino PEG-23 acid (MW 1146.4) and Amino PEG-35 acid (MW 1675.0). For bioconjugation in pharmaceutical applications.
• PEG Esters and Acids Monodisperse PEG esters, propionic acids, diacids, and protected forms (Boc, Fmoc, tBu) used as linkers and spacers in peptide synthesis, bioconjugation, and pharmaceutical formulations.
• PEG Thiols and Disulfides Monodisperse PEG derivatives with thiol groups and disulfide linkages for thiol-reactive bioconjugation and reversible conjugation via disulfide exchange.
• Special Reagents (Biotin PEGs and NHS Esters) Monodisperse PEG-based specialty reagents including biotinylated PEGs, heterobifunctional maleimide/NHS ester PEGs, and pyridyl disulfide PEG NHS esters for biotinylation, controlled bioconjugation, and reversible conjugation.
• Monodisperse Polypropylene Glycol (PPG) First-ever high-purity, monodisperse PPG product line developed by Polypure. Designed for hydrophobic drug delivery applications and exhibits thermoresponsive LCST behavior for controlled drug release and smart responsive materials.
• Custom Synthesis Services Bespoke synthesis and production of high-purity monodisperse PEG and PPG materials for clients with specialized requirements, available in multi-kilogram quantities. Customers engage Polypure via direct inquiry.

Quantifiable outcome

• Oligomer purity >99% achieved through proprietary purification technology
• +1 more outcomes

Named customers1 record

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Three partnerships are on record, tiered core.

• PAVE ConsortiumcoreStrategic or Co-development Partner · 1 January 2021EU-funded research project (MSCA Grant #861190) focused on immunotherapy-driven strategies for pancreatic cancer treatment. Polypure's role is to develop PEG products for vaccine technologies including lipid nanoparticles (LNPs) and peptide-based vaccines.
• NOVA-MRI ConsortiumcoreStrategic or Co-development Partner · 1 January 2021EU-funded research project where Polypure supplies monodisperse PEG derivatives for various applications within the consortium.
• PIANO ConsortiumcoreStrategic or Co-development Partner · 1 January 2021EU-funded research project where Polypure provides high-purity PEG derivatives and uniform PPG oligomers to consortium partners.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Biopharma PEG: U.S.-based supplier specializing in monodisperse and discrete PEG products for PEGylation and drug delivery. Closest functional match to Polypure in monodisperse PEG derivatives for pharma/biotech.
• Laysan Bio: U.S. manufacturer of PEG derivatives and PEGylation reagents including multi-arm, mPEG, and heterobifunctional PEGs. Comparable catalog and pharmaceutical/biotech customer base to Polypure.
• Jenkem Technology: PEG derivative supplier offering standard and custom PEG products across molecular weights. Overlaps with Polypure in PEG reagents and bioconjugation chemistry.
• Creative PEGWorks: Specialty supplier of PEG derivatives and PEGylation reagents including monodisperse PEG, mPEG, and heterobifunctional linkers. Directly competes in the same monodisperse PEG chemistry niche as Polypure.
• Iris Biotech: German PEG and bioconjugation reagent manufacturer offering monodisperse PEGs, PEG lipids, and custom synthesis. Comparable European specialty supplier with overlapping catalog to Polypure.
• NOF Corporation: Japanese specialty chemical company that supplies pharmaceutical-grade PEG-lipids and PEG derivatives, including SUNBRIGHT branded monodisperse PEGs used in LNPs and approved biologics. Direct competitor in pharma-grade PEG chemistry.

Broad incumbents

• Merck KGaA (Sigma-Aldrich): Life science giant offering broad PEG reagent and bioconjugation product lines plus custom chemistry. Competes with Polypure on catalog breadth and global distribution rather than on monodisperse specialty chemistry.
• Thermo Fisher Scientific (Pierce): Major life sciences supplier with PEGylation reagents and bioconjugation chemistry within its Pierce portfolio. Competes with Polypure as a broad incumbent rather than a monodisperse specialist.

Emerging players

• Biomatrik: PEG and biopolymer derivative supplier focused on biomedical and pharmaceutical applications. Smaller player with comparable monodisperse PEG offering and emerging custom synthesis capabilities.
• ChemPep: Specialty custom synthesis provider of PEG peptides and PEG-based polymers for pharma and biotech. Overlaps with Polypure in custom PEG synthesis services for smaller specialty customers.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Polypure