Spenglersan

What Spenglersan does

Spenglersan GmbH is a German family-owned pharmaceutical company headquartered in Bühl, Baden-Württemberg, with a secondary sales office in Bad Neuenahr-Ahrweiler. Founded in 1936 by Paul A. Meckel to commercialise the antigen-antitoxine immunotherapy developed by Dr. med. Carl Spengler in early-20th-century Davos, the company was rebranded from 'Paul Meckel Pharmazeutische Spezialitäten' to Spenglersan GmbH in 2014. It manufactures and distributes registered homeopathic and immunotherapeutic medicines under §38 of the German Medicines Act (apothekenpflichtige Arzneimittel), with all production conducted in-house at a GMP-certified facility.

The product portfolio is organised around two pillars: (1) Spenglersan Immunotherapy — ten colloidal preparations (Kolloide A, D, Dx, E, G, K, M, Om, R, T) applied topically via spray to the crook of the elbow, supported by the Spenglersan Blut-Test diagnostic that matches colloids to patients via blood agglutination; and (2) the Entoxin line of 13+ complex homeopathic remedies developed by Dr. med. Ewald Kleine for biological detoxification, acquired with Kleine&Steube Entoxin GmbH in 1993. The portfolio is rounded out by dermatological products (Creme and Bodylotion containing proprietary ImmunModulationsWasser), acid-base balance supplements (BASASAN), gut health products (Testisan, Lactasan), and GINKGOSAN for microcirculation.

Revenue is generated through a dual distribution model: apothekenpflichtige products are dispensed via German retail pharmacies and a network of online pharmacy partners (DocMorris, Shop-Apotheke, aponeo, apo-discounter, apotal, medikamente-per-klick), alongside direct B2C sales through the company's own shop (shop.spenglersan.de). The primary go-to-market targets licensed medical professionals — physicians, Heilpraktiker, and pharmacists — served through a gated Fachkreise platform providing therapy concepts, studies, CME-accredited webinars, and a practitioner certification programme. The company employs approximately 12 staff, operates exclusively in Germany, has received no institutional funding, and remains under family ownership with Dr. Kathrin Koll and Udo Kaufmann as Managing Directors.

Name

Spenglersan

Legal name

Spenglersan GmbH

Website

https://spenglersan.de

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

11–50 employees

Short description

Spenglersan GmbH is a German family-owned manufacturer of registered homeopathic immunotherapeutics, producing colloidal Spenglersan Kolloide and Entoxin remedies in Bühl for distribution through German pharmacies and its online shop, serving medical professionals and consumers.

Ownership category

akta.pro rank

Product category

Homeopathic Pharmaceuticals

NAICS

Pharmaceutical Preparation Manufacturing (325412), Drugs and Druggists' Sundries Merchant Wholesalers (42421), Health and Personal Care Retailers (456)

SIC

Pharmaceutical Preparations (2834), Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro primary industry

Dermatology Specialty Pharmaceuticals (HLAIACAL)

akta.pro secondary industries

Dermatology OTC & Skin Health (Acne Treatments, Eczema/Psoriasis OTC, Antifungals, Wart Removal) (CRADAMAF), Dermocosmetics & Medical-Grade Skincare (CRABAAAF), Pulmonology & Allergy Specialty Pharmaceuticals (HLAIACAF)

Keywords

• Homeopathic pharmaceuticals
• Immunotherapy products
• Natural medicine remedies
• Cosmeceutical skincare
• Dietary supplements

Headquarters

HQ city

Rastatt

HQ country

Germany

HQ region

Europe

Offices3 records

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Supply Chain, Marketing or Sales, Technology or R&D

Revenue model

1. Spenglersan Kolloide (Immunotherapy Products): Core revenue driver — topical colloidal immunotherapeutic preparations sold in pharmacies and via the company's own online shop. Products are applied by spraying onto skin. Sold as registered pharmacy-only medicines (apothekenpflichtige Arzneimittel) under §38 Arzneimittelgesetz.
2. Entoxin Complex Remedies: 13 registered homeopathic complex remedies targeting specific organ systems (liver/gallbladder, respiratory, gastrointestinal, urinary, cardiovascular). Sold through pharmacies and online shop. Revenue from repeat purchases.
3. BASASAN / BASASAN Vital (Acid-Base Balance Supplements): Dietary supplements supporting acid-base metabolism, including BASASAN Vital capsules (zinc, calcium citrate, L-cysteine) and BASASAN base baths. Sold through pharmacies and online shop.
4. Testisan and Lactasan (Gut Health Supplements): Dietary supplements for gut flora support — Testisan with 7 bacterial strains and inulin, Lactasan with calcium, zinc, lactic acid, apple cider vinegar powder and inulin. Sold through pharmacies and online shop.
5. Spenglersan Creme and Bodylotion (Cosmeceuticals): Cosmeceutical skincare products containing ImmunModulationsWasser, sweet almond oil, beeswax, and urea. Positioned at the intersection of cosmetics and dermatological care. Sold through pharmacies and online shop.
6. GINKGOSAN (Ginkgo biloba Preparation): Registered homeopathic medicine based on Ginkgo biloba leaves in D4 potency. Indicated for microcirculation support, memory, concentration, and tinnitus. Sold as pharmacy-only medicine.
7. Online Shop Direct Sales: Direct B2C e-commerce sales via shop.spenglersan.de to end consumers in Germany. Payment methods include SEPA direct debit, PayPal, advance bank transfer, and invoice. A minimum order value may apply. B2C transaction-based revenue.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels9 records

Core offering

Spenglersan GmbH manufactures and distributes homeopathic colloidal immunotherapy products (the Spenglersan Kolloide applied topically by spray), Entoxin complex remedies for elimination therapy, the Spenglersan Blut-Test diagnostic system, dermatological cosmeceuticals (Creme and Bodylotion containing ImmunModulationsWasser), the Ginkgo-based Ginkgosan homeopathic medicine, and dietary supplements (BASASAN, Testisan, Lactasan). Products are sold as pharmacy-only medicines and supplements through German retail pharmacies, online pharmacy partners, and the company's own online shop, with a separate professional ordering channel for medical practitioners.

Product overview

Spenglersan GmbH is a German family-owned pharmaceutical company producing natural remedies rooted in over 100 years of tradition, originating from the research of Dr. med. Carl Spengler and Dr. med. Ewald Kleine. The portfolio is organized around two core pillars: (1) Spenglersan® Immunotherapy — centered on 10 colloidal homeopathic preparations (Kolloid A, D, Dx, E, G, K, M, Om, R, T) applied via spray to the crook of the elbow, supported by the Spenglersan® Blut-Test diagnostic system and a kinesiological Testsatz; and (2) the Entoxin® Therapy — 13 complex homeopathic preparations (including Fella-Entoxin, Matrix-Entoxin, Uresin-Entoxin, Erkältungs-Entoxin, Broncho-Entoxin, Magen-Darm-Entoxin, Neolin-Entoxin, Viscum-Entoxin, D.B.-Entoxin, Adenolin-Entoxin, Prostata-Entoxin, and Spasmo-Entoxin) developed by Dr. Kleine for biological detoxification and elimination therapy. These are sold individually and in therapeutic combination sets (Allergie-Set, Erkältungs-Set, Blutdruck-Set, Entoxin Set). Supporting the core portfolios are Ginkgosan® (Ginkgo biloba homeopathic product), dermatological products (Spenglersan® Creme and Bodylotion with ImmunModulationsWasser), acid-base balance products (BASASAN® Vital capsules and BASASAN® Basenbad), and gut health supplements (Testisan® with 7 bacterial strains and Lactasan®). All products are manufactured in Bühl, Germany, under GMP conditions.

Differentiator

Problem solved

Functional benefit

Brands

• Ginkgosan: Ginkgo biloba-based homoeopathic product for memory, concentration, and tinnitus support.
• BASASAN
• Lactasan
• Testisan
• Entoxin

Products and services

• Spenglersan Kolloid A

Quantifiable outcome

• The Spenglersan Blut-Test enables individualised colloid selection based on agglutination response, allowing tailored immunotherapy protocols per patient
• +1 more outcomes

Named customers4 records

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Three partnerships are on record, tiered core and minor.

• Prof. Dr. Gerhard Bundschuh (Institut für Medizinische Immunologie, Charité Berlin)coreStrategic or Co-development Partner · 1 January 1990University research collaboration beginning in the 1990s. Prof. Dr. Bundschuh (founder of the Institut für Medizinische Immunologie at Charité Berlin) led scientific and clinical studies that validated the efficacy of Spenglersan Kolloide. His work established the immunological basis for the antigen-antitoxine immunotherapy approach and was instrumental in gaining academic credibility for the products.
• Prof. Dr. med. Rainer Klopp (Institut für Mikrozirkulation, Charité Berlin)coreStrategic or Co-development Partner · 1 January 1990University research collaboration beginning in the 1990s. Prof. Dr. Klopp (founder of the Institut für Mikrozirkulation at Charité Berlin) contributed scientific and clinical evidence on the mechanisms and efficacy of Spenglersan Kolloide. Together with Prof. Bundschuh, his research at Charité Berlin was a catalyst for international research projects, including those supported by the WHO.
• Online Pharmacy Partners (DocMorris, aponeo, Shop-Apotheke, apo-discounter, apotal, medikamente-per-klick)minorChannel Partner/ Reseller/ DistributorSpenglersan products are distributed through major German online pharmacy platforms including DocMorris, aponeo, Shop-Apotheke, apo-discounter, apotal, and medikamente-per-klick. These partners extend the company's reach to online consumers beyond the proprietary e-commerce shop.

Scale indicators3 records

Recent moves9 records

Expansion highlights4 records

Direct peers

• Dr. Willmar Schwabe GmbH & Co. KG: Major German homeopathic pharmaceutical manufacturer producing single remedies and complex preparations distributed through German pharmacies. Highly comparable in homeopathic regulatory positioning, Kolloid-adjacent immune support category, and German practitioner/patient target segments.
• ISO-Arzneimittel GmbH & Co. KG: German manufacturer specialising in homeopathic and anthroposophic medicines distributed through pharmacies. Comparable in mid-sized German homeopathic pharma positioning, regulatory registrations, and complementary medicine practitioner targeting.
• Biologische Heilmittel Heel GmbH: One of the largest German homeopathic pharmaceutical manufacturers, producing combination homeopathic medicines for immune and systemic support. Heel is the most direct peer to Spenglersan in terms of homeopathic regulatory positioning, German GMP manufacturing, and distribution through German pharmacies, but operates at significantly larger scale.
• Pascoe pharmazeutische Präparate GmbH: German family-owned pharmaceutical company producing natural medicines, homeopathic remedies, and dietary supplements, distributed through German pharmacies. Comparable in family-owned SME profile, complementary medicine focus, and pharmacy distribution model.
• Wala Heilmittel GmbH: German manufacturer of anthroposophic and homeopathic medicines including immunotherapy-adjacent remedies. Directly comparable in natural medicine portfolio breadth, German GMP manufacturing, and practitioner/patient dual-channel distribution.
• Deutsche Homöopathie-Union (DHU-Arzneimittel GmbH & Co. KG): Leading German manufacturer of homeopathic single remedies and complex preparations, distributed through German pharmacies. Directly comparable to Spenglersan in homeopathic pharmacy-only positioning and German regulatory framework, with overlapping practitioner (Heilpraktiker, physician) target customers.
• Sanum-Kehlbeck GmbH & Co. KG: German manufacturer of homeopathic, isopathic, and biological medicines for immune and microbial balance therapy. Highly comparable in immunotherapy-adjacent positioning, German pharmacy distribution, and Heilpraktiker/practitioner customer segments.
• Hevert Arzneimittel GmbH & Co. KG: German family-owned manufacturer of homeopathic and phytopharmaceutical medicines, distributed through German pharmacies. Comparable in family-owned SME profile, homeopathic regulatory framework, and complementary medicine practitioner focus.
• Infirmarius GmbH: German manufacturer of homeopathic complex remedies and spagyric medicines distributed through German pharmacies. Comparable in mid-sized German homeopathic pharma positioning, complex remedy portfolio structure (similar to Entoxin line), and Heilpraktiker/practitioner customer focus.
• Weleda AG: Swiss-German manufacturer of anthroposophic medicines and natural cosmetics with pharmacy distribution across Germany. Comparable in natural/holistic positioning and German pharmacy channel, with particular overlap in the dermatology/cosmeceutical product category where Spenglersan Bodylotion and Creme compete.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/spenglersan.original
• LinkedInlinkedin.com/company/spenglersan
• Instagraminstagram.com/spenglersan_gmbh

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Spenglersan