Fondazione Casa Sollievo della Sofferenza

What Fondazione Casa Sollievo della Sofferenza does

Fondazione Casa Sollievo della Sofferenza is an Italian religious foundation (Fondazione di Religione e di Culto) headquartered in San Giovanni Rotondo (Puglia) and operating under direct Holy See oversight, with the President and Board appointed by the Vatican Secretary of State. Founded in 1956 by Saint Pio da Pietrelcina, the foundation runs Casa Sollievo della Sofferenza, one of Italy's largest polyclinics, designated as an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) for Oncology, Neurology and Diagnostics since 1991 and re-confirmed by decree of October 23, 2023. It functions as a classified religious hospital within the Italian National Health Service (SSN), serving SSN-reimbursed patients, private-pay patients, rare disease cohorts, oncology patients, and pediatric patients across inpatient, outpatient, emergency, and surgical care lines; its main campus spans approximately 100,000 sqm, supplemented by the Poliambulatorio Giovanni Paolo II (25,000 sqm, 60 specialist clinics) and satellite dialysis centers in Manfredonia, Rodi Garganico, and Vieste.

The foundation's core products and infrastructure include the main hospital, the ISBREMIT research center (one of few Italian facilities with a GMP-compliant cell factory for clinical stem cell production), the Istituto CSS-Mendel in Rome for medical genetics (acquired in 1998), a PET-TAC diagnostic center, Da Vinci robotic surgery, stereotactic radiotherapy, and an advanced cardiac surgery program. Digital services (online appointment booking, online report retrieval, online clinical record access, teleconsultation, and a virtual service desk) extend the service surface beyond the physical campus. The research portfolio spans genetic and hereditary-familial diseases, innovative therapies, regenerative medicine, oncology, neurology, and rare diseases, organized across multiple specialized research units (Cancer Stem Cells, Cancer Biomarkers, Bioinformatics, Tissue Engineering, Huntington, Cellular Reprogramming, Advanced Therapies Production, and others).

The business model combines SSN tariff-based reimbursement for standard inpatient and outpatient services, private medical service fees for patients opting out of SSN, voluntary donations from the global community of Padre Pio Prayer Groups, 5x1000 tax designations, and public research funding (notably PNRR / NextGenerationEU grants for projects including RECOUNT, OMIC PROFILE IN AUTISM SPECTRUM DISORDER, and patient-derived organoids research). The foundation operates as a private nonprofit religious entity — its legal name is Fondazione di Religione e di Culto Casa Sollievo della Sofferenza — and is supervised jointly by the Holy See and the Italian Ministry of Health. Headcount is in the 5,001-10,000 range, and the recently presented 2024-2029 Strategic Plan targets positive net equity with EBITDA turning positive in 2025, supported by a 73 million euro supplier agreement.

Name

Fondazione Casa Sollievo della Sofferenza

Legal name

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza

Website

https://operapadrepio.it

Company type

Private

Founded year

1956

Operating status

Operating

Headcount range

5,001–10,000 employees

Short description

Fondazione Casa Sollievo della Sofferenza is an Italian religious foundation under Holy See oversight that operates IRCCS Casa Sollievo, a large polyclinic in San Giovanni Rotondo providing inpatient, outpatient, and research services in oncology, neurology, regenerative medicine, and rare diseases to SSN and private patients.

Ownership category

akta.pro rank

Product category

Hospital Healthcare Services

NAICS

General Medical and Surgical Hospitals (6221), Specialty (except Psychiatric and Substance Abuse) Hospitals (622310), Offices of Physicians (62111)

SIC

Services-General Medical & Surgical Hospitals, Nec (8062), Services-Hospitals (8060)

akta.pro primary industry

Oncology & Cancer Specialty Hospitals (HLAFAHAC)

akta.pro secondary industry

Neurology & Neurosurgical Specialty Hospitals (HLAFAHAD)

Keywords

• Hospital healthcare services
• Medical research and treatment
• Oncology neurology diagnostics
• Regenerative medicine research
• Rare disease treatment

Headquarters

HQ city

San Giovanni Rotondo

HQ country

Italy

HQ region

Europe

Offices5 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Supply Chain, Others

Revenue model

1. Italian National Health Service (SSN) Reimbursements: As an accredited religious hospital classified within the Italian National Health System, Casa Sollievo receives reimbursement for medical services provided to patients under the public healthcare system.
2. Private Medical Services: Private medical examinations and diagnostic services for patients choosing private healthcare options outside the SSN framework.
3. 5x1000 Tax Designations: Receives 5x1000 tax designations from Italian taxpayers for scientific research activities.
4. Research Grants and Funding: PNRR (Piano Nazionale di Ripresa e Resilienza) and other government research funding for specific research projects.
5. Donations: Voluntary donations from supporters and devotees of San Pio da Pietrelcina worldwide.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels6 records

Core offering

Fondazione Casa Sollievo della Sofferenza operates an IRCCS-classified religious hospital in San Giovanni Rotondo, Italy, delivering comprehensive inpatient and outpatient medical, surgical, and diagnostic care across multiple specialties. It also runs scientific research programs in genetics, regenerative medicine, oncology, and neurology, supported by the ISBREMIT stem cell production facility, Istituto CSS-Mendel in Rome, the Poliambulatorio Giovanni Paolo II outpatient complex, and satellite dialysis centers across Puglia.

Product overview

Fondazione Casa Sollievo della Sofferenza operates a multi-component healthcare and research ecosystem centered around IRCCS Casa Sollievo della Sofferenza hospital, a renowned medical facility in San Giovanni Rotondo. The institution encompasses the main hospital providing inpatient and outpatient services across multiple departments, the Poliambulatorio 'Giovanni Paolo II' outpatient complex with 60 specialist clinics, ISBREMIT for stem cell and regenerative medicine research with GMP-compliant production facilities, and Istituto CSS-Mendel in Rome for clinical genetics. Digital health services include online appointment booking (Prenotazioni Online), online report retrieval (Ritiro Referti), medical record access (Cartella Clinica Online), teleconsultation (Televisita), and virtual service desk (Sportello Virtuale). Specialized diagnostic services include the PET-TAC imaging center. Educational offerings comprise ECM continuing medical education courses and SIUMB ultrasound training programs.

Differentiator

Problem solved

Functional benefit

Products and services

• Casa Sollievo della Sofferenza (IRCCS Hospital) IRCCS hospital in San Giovanni Rotondo, Italy, offering comprehensive inpatient and outpatient medical services across multiple specialties including emergency care, surgery, diagnostics, and scientific research in genetics, regenerative medicine, oncology, and neurology.
• Poliambulatorio Giovanni Paolo II 25,000 square meter outpatient complex in San Giovanni Rotondo with 60 specialist clinics across 7 floors, featuring advanced diagnostic equipment and centralized appointment booking system (CUP).
• ISBREMIT (Institute for Stem-cell Biology, Regenerative Medicine and Innovative Therapies) State-of-the-art research center for stem cell biology, regenerative medicine and innovative therapies, housing a GMP-compliant cell factory and biopharmaceutical production laboratory — one of few such facilities in Italy.
• Istituto CSS-Mendel (Rome) Research institute in Rome providing integrated clinical genetics consultation and advanced diagnostic services for genetic diseases. Founded by Luigi Gedda in 1953 and donated to Casa Sollievo della Sofferenza in 1998.
• Prenotazioni Online (Online Appointments) Online portal for requesting or canceling medical appointments via form submission, with callback from the CUP contact center.
• Ritiro Referti Online (Online Report Retrieval) Secure online portal for accessing radiology and laboratory examination results conducted at the facility.
• Ritiro Cartella Clinica Online (Online Medical Record Retrieval) Service enabling patients to request, pay for, and download medical records directly from a computer or mobile device.
• Televisita (Teleconsultation) Remote medical consultation service allowing patients to receive healthcare follow-up from home in a secure environment.
• Sportello Virtuale (Virtual Service Desk) Online portal for registering medical prescriptions, printing invoices, and making credit card payments.
• Centro PET-TAC Positron emission tomography and computed tomography diagnostic center for advanced oncological imaging, diagnostics, and treatment planning.
• Corsi ECM (Continuing Medical Education) Regional provider since 2012 for continuing medical education courses, offering both internal training programs and external professional development events in Puglia.
• Scuola SIUMB (Ultrasound Training) Ultrasound training programs including courses on musculoskeletal, thoracic, and internal medicine sonography, affiliated with SIUMB (Società Italiana di Ultrasonologia in Medicina e Biologia).

Quantifiable outcome

• IRCCS recognition for Oncology, Neurology, and Diagnostics since 1991, re-confirmed October 2023
• +2 more outcomes

Named customers1 record

Segments5 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Five partnerships are on record, tiered core and moderate.

• Università degli Studi di FoggiacoreStrategic or Co-development Partner · 1 January 1956Casa Sollievo della Sofferenza hosts the Corso di Laurea in Scienze Infermieristiche (Nursing Degree Program) of the Faculty of Medicine and Surgery of the University of Foggia.
• Università degli Studi di Roma La SapienzacoreStrategic or Co-development PartnerThe CSS-Mendel Institute in Rome is a teaching site for the School of Specialization in Medical Genetics of the Faculty of Medicine and Surgery of Sapienza University of Rome.
• Various Italian UniversitiesmoderateStrategic or Co-development PartnerCollaborative scientific and training relationships with nearly all Italian universities and numerous other IRCCS (Scientific Institutes for Research, Hospitalization and Healthcare).
• Italian Ministry of HealthcoreStrategic or Co-development PartnerWorks in close contact with the Ministry of Health and major Italian and European research centers for clinical research activities.
• Università Cattolica del Sacro Cuore di RomacoreStrategic or Co-development PartnerScientific Director Ornella Parolini is a full professor of Cellular Biology Applied to Medicine at the Faculty of Medicine of Università Cattolica del Sacro Cuore in Rome.

Scale indicators8 records

Recent moves3 records

Expansion highlights6 records

Broad incumbents

• ASST Papa Giovanni XXIII: Large Italian public hospital and reference center in Bergamo; broadly comparable in scale, SSN reimbursement model, and multi-specialty academic hospital positioning.
• Mayo Clinic: Global benchmark for integrated clinical care, research, and education at a not-for-profit research hospital; thematically comparable as a large-scale non-profit academic medical center combining specialty research with broad clinical services.
• ASST Grande Ospedale Metropolitano Niguarda: Major public general and specialty hospital in Milan operating within the SSN with research activity; broadly comparable as a large Italian public hospital with multiple specialty services and research infrastructure.
• IRCCS Ospedale San Raffaele: Large multi-specialty research hospital and IRCCS in Milan affiliated with Vita-Salute San Raffaele University; broadly comparable in scale, advanced technology adoption (robotic surgery, regenerative medicine), and academic medical center positioning.

Direct peers

• Fondazione IRCCS Istituto Neurologico Carlo Besta: Milan-based neurology specialty IRCCS; directly comparable on the neurology research line of Casa Sollievo's IRCCS designation and on its foundation/non-profit governance structure.
• Fondazione Poliambulanza: Brescia-based non-profit hospital with research activity (including the CREM regenerative medicine center previously directed by Casa Sollievo's new Scientific Director); closely comparable in non-profit Italian hospital model with active regenerative medicine research.
• Istituto Europeo di Oncologia (IEO): Milan-based oncology specialty hospital also recognized as an IRCCS; directly comparable in IRCCS research status, oncology specialty focus, and Italian public-private hospital structure.
• Istituto Nazionale dei Tumori (INT) - Milan: Italy's national cancer institute and IRCCS dedicated to oncology research and treatment; directly comparable in oncology research depth, IRCCS designation, and public-hospital status within the Italian SSN.
• Fondazione Policlinico Universitario Agostino Gemelli IRCCS: Large Catholic-affiliated IRCCS university hospital in Rome; directly comparable in religious-affiliated governance, multi-specialty academic hospital model, and IRCCS research designation.
• IRCCS Istituto Clinico Humanitas: Research hospital with IRCCS designation near Milan integrating clinical care, research, and teaching; closely comparable in IRCCS status, research-clinical integration, and Italian private-academic hospital positioning.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/playlist?list=PLqIQP-t63nGB9264WMDdw_gYrau0JDp3o&si=nhNMAqPP3YDFASVD
• Xx.com/operapadrepio
• Facebookfacebook.com/operapadrepio
• LinkedInlinkedin.com/company/operapadrepio

Revenue estimate

Valuation estimate

Number of profiles

Profiles13 records

Subsidiaries7 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Fondazione Casa Sollievo della Sofferenza