Bionos Biotech
Bionos Biotech is a Valencia-based CRO (founded 2013, Hospital La Fe spin-off) that runs in vitro, ex vivo, and in vivo efficacy studies for cosmetic, food, and nutraceutical clients internationally, using proprietary imaging scanners and validated Medaka fish models.
- Company typePrivate
- Founded2013
- HeadquartersValencia, Spain
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Bionos Biotech does
Bionos Biotech S.L. is a Valencia-based contract research organization (CRO) founded in January 2013 as a spin-off from the Developmental Biology Laboratory at Hospital La Fe. The company designs and executes efficacy studies for the cosmetic and food-nutraceutical industries, using in vitro, ex vivo, and in vivo methodologies, and operates from the Biopolo at Hospital Universitario y Politécnico La Fe. Its portfolio spans cosmetic efficacy testing (anti-aging, depigmentation, anti-pollution, UV-IR-HEV protection, hair care, anti-inflammatory, epigenetic, antioxidant, firming, regeneration, skin penetration studies), food/nutraceutical clinical trials (functional food, toxicology, metabolism, enzymatic activity, regenerative capacity), and pharmaceutical dermatological actives research.
Bionos differentiates through proprietary technical platforms — including the Bio Blue Light Scanner for high-resolution cutaneous surface evaluation, the Bio3D Structured-Light Scanner for volumetric clinical analysis, a validated Medaka (Oryzias latipes) fish model platform for antioxidant and anti-aging screening, and skin microbiome analysis — supported by peer-reviewed publications and partnerships with IIS-La Fe, CIPF, UPV, Isdin, Mibelle Biochemistry, and others. The company is ISO 9001:2015 certified, registered as a Sanitary Center (No. 22043) with the Generalitat Valenciana, and holds EIBT and Pyme Innovadora accreditations.
The business model is quote-based professional services revenue from B2B clients, with 135+ international customers (50% of 2019 revenue from international billing), reach through trade shows (IFSCC, In-Cosmetics Global/Asia, Cosmetorium, Supplier's Day NYC), and direct commercial contact. In 2020 the company launched a Testing by Bionos sub-brand for COVID-19 PCR and antibody testing services, and it participates in EU-funded consortia (PHOCNOSIS, AlgaeCeuticals, BRYOMOLECULES, EDUALGAE, SINUé). Funding has been limited to public grants (CDTI NEOTEC 2015, Valencia Emprende SEED, IVACE 2022) with no disclosed institutional venture capital.
Bionos Biotech firmographics
Firmographics- Name
- Bionos Biotech
- Legal name
- Bionos Biotech S.L.
- Website
- https://bionos.es
- Company type
- Private
- Founded year
- 2013
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Bionos Biotech is a Valencia-based CRO (founded 2013, Hospital La Fe spin-off) that runs in vitro, ex vivo, and in vivo efficacy studies for cosmetic, food, and nutraceutical clients internationally, using proprietary imaging scanners and validated Medaka fish models.
- Ownership category
- akta.pro rank
Bionos Biotech industry classification
Industry- Product category
- Contract Research Organization (Cosmetic & Food Efficacy Testing)
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)
- akta.pro primary industry
- Cell-Based & Potency Assays (Bioassays) (HLAGADAH)
- akta.pro secondary industries
- Clinical CROs (Phase I–IV) (HLAGAAAA), Toxicology & Safety Assessment CROs (GLP) (HLAGAAAC), Bioanalytical & Biomarker CROs (PK/PD/Immunogenicity) (HLAGAAAD), Central Laboratory & Clinical Trial Testing CROs (HLAGAAAE)
Keywords
Where Bionos Biotech is headquartered
LocationHeadquarters
- HQ city
- Valencia
- HQ country
- Spain
- HQ region
- Europe
Offices2 records
Markets served
Bionos Biotech business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales
Revenue model
- Efficacy Studies for Cosmetics: Contract research services providing efficacy testing for cosmetic products and ingredients. Services include anti-aging, depigmentation, anti-pollution, UV-IR-HEV protection, hair care, anti-inflammatory, epigenetic, antioxidant, firming, regeneration, and skin penetration studies.
- Clinical Trials for Food Industry: Clinical efficacy testing services for functional foods, toxicology, metabolism, enzymatic activity, and regenerative capacity studies.
- COVID-19 Diagnostic Testing (Testing by Bionos): PCR and antibody testing services for public and private entities including regional health authorities, companies, nursing homes, hospitals, health insurance funds, and schools. Performed 200-400 daily analyses during pandemic.
Go-to-market motion2 records
Distribution channels3 records
Marketing channels4 records
Bionos Biotech product offering
Product offeringCore offering
Bionos Biotech is a Contract Research Organization (CRO) specialized in efficacy testing for the cosmetic and food-nutraceutical industries. The company designs and develops bioassays using in vitro, ex vivo, and in vivo methodologies to scientifically validate product claims for anti-aging, depigmentation, anti-pollution, UV-IR-HEV protection, hair care, anti-inflammatory, antioxidant, firming, regeneration, and skin penetration applications. It also operates a Testing by Bionos sub-brand for COVID-19 diagnostic testing services.
Product overview
Bionos Biotech is a Contract Research Organization (CRO) offering a comprehensive portfolio of efficacy studies for the cosmetic and food industries. The core offering consists of bioassays conducted through three methodological approaches—in vitro, ex vivo, and in vivo—spanning cosmetic efficacy testing (anti-wrinkle, depigmenting, UV protection, hair care, antioxidant, and skin penetration studies) and food clinical trials (functional food, toxicology, metabolism). Proprietary technology platforms include the Bio Blue Light Scanner for high-resolution skin imaging and the Bio3D Structured-Light Scanner for volumetric analysis. The company operates a sub-brand, Testing by Bionos, for COVID-19 diagnostic services. Bionos also participates in collaborative EU-funded research projects including BRYOMOLECULES (bryophyte bioactive compounds) and EDUALGAE (microalgae-based sweeteners).
Differentiator
Problem solved
Functional benefit
Products and services
- In Vitro Bioassays (Bioensayos In Vitro) Laboratory-based efficacy studies using in vitro methods for cosmetic and food industry products, analyzing biological responses in controlled environments outside living organisms. Serves cosmetic and food companies requiring molecular-level and cellular efficacy data.
- Ex Vivo Bioassays (Bioensayos Ex Vivo) Efficacy testing using living tissue or cells maintained outside the body, bridging in vitro and in vivo approaches for product validation. Serves cosmetic and food companies seeking intermediate-complexity biological testing.
- In Vivo Bioassays (Bioensayos In Vivo) Clinical efficacy studies conducted with human volunteers to validate cosmetic and food product claims under real-use conditions. Serves cosmetic and food companies seeking human clinical evidence.
- Cosmetic Efficacy Studies (Ensayos Cosmética) Comprehensive efficacy testing services for cosmetic products including anti-wrinkle, depigmenting, anti-pollution, UV-IR-HEV protection, anti-aging, hair care, anti-inflammatory, epigenetic, antioxidant, firming, regeneration, and skin penetration studies. Serves cosmetic and personal care companies.
- Food Clinical Trials (Ensayos Alimentación) Clinical trials and efficacy studies for the food industry including functional food, toxicology, metabolism, enzymatic activity, and regenerative capacity assessments. Serves food and beverage companies requiring health-claim validation.
- Testing by Bionos (COVID-19 Diagnostic Testing) Dedicated COVID-19 testing service brand offering PCR and antibody tests with response times under 24 hours. Serves public health authorities, companies, nursing homes, hospitals, health insurance funds, and schools. Performed 200-400 daily analyses during the pandemic.
Quantifiable outcome
- 1,750+ products and ingredients tested
- +3 more outcomes
Companies that use Bionos Biotech
Customer profileNamed customers4 records
Segments3 records
Ideal customer profiles3 records
Bionos Biotech technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
Bionos Biotech partnerships and signals
Strategic signalPartnerships
17 partnerships are on record, tiered core and secondary.
- EDUALGAE ProjectcoreResearch project for developing natural sweeteners from lichenic microalgae as sugar substitutes for bakery and pastry products.
- BRYOMOLECULES Consortium (EU)coreEU-funded initiative for systematic search of bioactive compounds from European bryophytes (mosses and liverworts) for sustainable cosmetic and pharmaceutical applications. Documentary released in 2025.
- SINUÉ ProjectcoreSurgical planning solutions for brain tumors using identity habitats of gliomas enabling intraoperative immunotherapeutic treatment decisions.
- Eurofins Cosmetics & Personal CarecoreNetwork collaboration with Eurofins, described as having 30+ years of experience and leadership in cosmetics and personal care testing, for expanded testing capabilities and services.
- PhenocellsecondaryCollaboration in new venture combining Phenocell's capabilities with Bionos testing expertise.
- CTIBiotechsecondaryPartnership in new testing venture combining CTIBiotech's 3D tissue models with Bionos bioassay expertise.
- Hospital La Fe / Instituto de Salud Carlos IIIcoreCollaboration on COVID-19 epidemiological prevalence project during the pandemic.
- Mibelle BiochemistrycoreCollaboration to functionally validate MossCellTech No.1 active ingredient, which won In-Cosmetics Global Innovation Award 2018. Article published in Industria Cosmética magazine.
- AlgaeCeuticals (RISE H2020)coreEU RISE H2020 project exploring microalgae and cyanobacteria metabolites for beneficial applications in cosmetics and pharmaceuticals.
- Instituto de Investigación Sanitaria del Hospital La Fe (IIS-La Fe)coreCollaboration for antioxidant and anti-aging research using Medaka fish model. Joint publication in Rejuvenation Research demonstrating cocoa extract's protective effects against oxidative stress.
- Centro de Investigación Príncipe Felipe (CIPF)coreTrilateral collaboration with IIS-La Fe for research on cocoa extract antioxidant and anti-aging properties, validating Medaka as screening platform.
- IsdincoreCollaboration to demonstrate antioxidant capacity of topical melatonin using in vitro Medaka model, measuring gene expression of antioxidant enzymes (SOD1, CAT, Nrf2, GPx1).
- Beauty Cluster de BarcelonasecondaryCluster membership as first member joined in 2017, providing networking and ecosystem integration within Barcelona's beauty industry cluster.
- BIOVALsecondaryCluster membership as associated company in BIOVAL, the BIO sector cluster of the Valencian Community, for industry networking and collaboration.
- PHOCNOSIS Consortium (EU H2020)coreEU Horizon 2020 project for early diagnosis of cardiovascular diseases through portable device. Bionos participates in functional validation of the device. Led by UPV.
- Universitat Politècnica de València (UPV)coreMultiple collaborations including PHOCNOSIS project led by UPV's Nanophotonic Technology Center (NTC) and joint research initiatives.
- Inkemia IUCTcoreJoint venture agreement to research potential cosmetic ingredients and dermatological actives with biological action such as skin regeneration, repair, anti-aging and antioxidant effects.
Scale indicators13 records
Recent moves7 records
Expansion highlights6 records
Bionos Biotech competitors and assessment
Company assessmentBroad incumbents
- Eurofins Cosmetics & Personal Care: Global leader in cosmetics and personal care testing with 30+ years of experience. Already a network partner of Bionos and the dominant reference point in the segment where Bionos operates; directly comparable for efficacy, safety, and claim-substantiation services.
- SGS: Global TIC (testing, inspection, certification) major offering cosmetic product testing, clinical trials, and claim substantiation services. Comparable to Bionos on service overlap but vastly larger in scale and geographic reach.
- Intertek: Multinational testing, inspection, and certification company with broad cosmetics and consumer products testing capabilities. Competes for the same enterprise R&D testing budgets as Bionos but at global scale.
- Charles River Laboratories: Large global CRO with established safety assessment, bioanalysis, and research services for cosmetics, chemicals, and pharma. Adjacent to Bionos in endpoints and regulatory expertise but at substantially larger scale.
- Eurofins CDMO / Eurofins Discovery: Wider Eurofins group offering discovery, bioanalytical, and in vitro pharmacology services. Competes for early-stage cosmetic/pharma R&D budgets that overlap with Bionos's efficacy screening work.
Direct peers
- Bioalternatives: France-based CRO specializing in in vitro and ex vivo efficacy testing for cosmetic and pharmaceutical ingredients. Closest comparable in niche: same methodologies, similar customer base (ingredient suppliers and cosmetic brands) and similar size class.
- CeeTox: US-based CRO focused on in vitro toxicology and efficacy testing for cosmetics, personal care, and pharmaceutical clients. Comparable scope in cell-based assays, claim-substantiation studies, and ingredient screening.
- SkinEthic / Episkin (L'Oréal): Provider of reconstructed human skin models and in vitro testing services for cosmetic, chemical, and pharmaceutical industries. Comparable offering on reconstructed tissue assays and claim-substantiation testing.
- XCellR8: UK-based CRO providing non-animal efficacy and safety testing for cosmetics and chemicals, including in vitro bioassays and skin sensitization. Highly comparable service mix and target customer base (ethical beauty, ingredient suppliers).
Emerging players
- Phylogene: France-based CRO offering biomarker, omics, and bioassay services to cosmetics and nutrition clients. Comparable in technical approach (molecular readouts, skin biology) and emerging-segment positioning.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat4 records
Key risks7 records
Key highlights7 records
Customer concentration
Bionos Biotech social profiles
Digital presenceBionos Biotech compliance and trust
Trust signalCompliance4 records
Bionos Biotech financial estimates
Financial estimateRevenue estimate
Valuation estimate
Bionos Biotech leadership team
Management profileNumber of profiles
Profiles2 records
Bionos Biotech funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Bionos Biotech M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Bionos Biotech
What does Bionos Biotech do?
Bionos Biotech is a Contract Research Organization (CRO) specialized in efficacy testing for the cosmetic and food-nutraceutical industries. The company designs and develops bioassays using in vitro, ex vivo, and in vivo methodologies to scientifically validate product claims for anti-aging, depigmentation, anti-pollution, UV-IR-HEV protection, hair care, anti-inflammatory, antioxidant, firming, regeneration, and skin penetration applications. It also operates a Testing by Bionos sub-brand for COVID-19 diagnostic testing services.
Is Bionos Biotech a public or private company?
Bionos Biotech is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Bionos Biotech founded?
Bionos Biotech was founded in 2013. It employs 11 to 50 people.
Where is Bionos Biotech based?
Bionos Biotech is headquartered in Valencia, Spain, in the Europe region.
How does Bionos Biotech make money?
Three revenue lines are on record. Efficacy Studies for Cosmetics are the primary driver. The others are clinical Trials for Food Industry and COVID-19 Diagnostic Testing (Testing by Bionos).
Who are Bionos Biotech's main competitors?
Broad incumbents on record are Eurofins Cosmetics & Personal Care, SGS, Intertek, Charles River Laboratories and Eurofins CDMO / Eurofins Discovery. Direct peers are Bioalternatives, CeeTox, SkinEthic / Episkin (L'Oréal) and XCellR8. Phylogene is listed as an emerging player.
Does Bionos Biotech have an API?
No public API is recorded for Bionos Biotech.
What industry is Bionos Biotech in?
Bionos Biotech's product category is Contract Research Organization (Cosmetic & Food Efficacy Testing). Its primary akta.pro industry code is HLAGADAH, Cell-Based & Potency Assays (Bioassays), with a secondary code of HLAGAAAA, Clinical CROs (Phase I–IV). Its NAICS code is 541714 and its SIC code is 8731.