PreAnalytiX

What PreAnalytiX does

PreAnalytiX GmbH is a Swiss specialty manufacturer (Hombrechtikon, Switzerland; 11–50 employees) that develops and commercializes the PAXgene product line — a portfolio of preanalytical specimen collection, stabilization, and processing systems used prior to molecular diagnostic testing. The company operates as a joint venture with QIAGEN N.V. and Becton, Dickinson and Company (BD), with QIAGEN handling global distribution through its webshop and field sales force across 70+ countries (China excluded). The portfolio covers five specimen types: blood (RNA, miRNA, genomic DNA, and circulating cell-free DNA tubes plus purification kits, with IVD and FDA-cleared variants), urine (the PAXgene Urine Liquid Biopsy Set for cfDNA, developed under a September 2024 three-way strategic alliance with QIAGEN and BD), saliva (DNA collector), tissue (a proprietary formalin-free, non-crosslinking FIX and STABILIZER system enabling combined histological and molecular analysis from a single specimen, plus RNA/miRNA and DNA purification kits), and bone marrow (RNA tubes and kits).

Underlying technology centers on proprietary stabilization chemistries that preserve nucleic acid integrity at room temperature, stabilize cfDNA in blood and urine for up to seven days, and — in the case of the Tissue System — avoid the destructive crosslinking of traditional formalin fixation, producing unmodified nucleic acids suitable for demanding downstream applications such as NGS. Products are tightly integrated with QIAGEN's downstream automated purification platforms (QIAcube, QIAsymphony SP) and QIAGEN purification kits, creating a system-level workflow rather than standalone consumables.

The revenue model is a per-kit/unit pricing consumables business (e.g., $241 for a 10-pack of PAXgene Tissue FIX Containers, $332 for a 4-liter STABILIZER unit), with one-time purchases of IVD or Research Use Only kits and recurring pull-through from purification consumables. Go-to-market is hybrid: digital e-commerce through the QIAGEN webshop for long-tail clinical and research lab buyers, supplemented by QIAGEN enterprise field sales for larger laboratory and hospital accounts, and amplified by scientific content marketing (knowledge hub, peer-reviewed publications, webinars, AMP conference participation, SPIDIA4P European preanalytical standardization project). The September 2024 strategic alliance with QIAGEN and BD is the most significant recent commercial signal, formalizing co-development of standardized urine liquid biopsy solutions and adding BD's medical device distribution to the existing QIAGEN channel.

Name

PreAnalytiX

Legal name

PreAnalytiX GmbH

Website

https://preanalytix.com

Company type

Private

Operating status

Operating

Headcount range

11–50 employees

Short description

PreAnalytiX GmbH is a Swiss specialty manufacturer (joint venture of QIAGEN and BD) that produces the PAXgene preanalytical specimen collection, stabilization, and processing systems used by clinical research labs, pathology labs, and liquid biopsy developers across 70+ countries.

Ownership category

akta.pro rank

Product category

Preanalytical specimen collection and processing for molecular diagnostics

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Sample Collection, Stabilization & Pre-Analytics (biobanking, transport media, extraction kits) (HLAAALAM)

akta.pro secondary industry

Sample Logistics, Biorepository & IVD Kit Management (Trial Support) (HLAGAEAI)

Keywords

• Preanalytical specimen collection
• Nucleic acid stabilization
• Blood collection tubes
• Formalin-free tissue fixation
• Liquid biopsy workflows

Headquarters

HQ city

Hombrechtikon

HQ country

Switzerland

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. PAXgene Tissue Products: Sale of tissue fixation containers, stabilizer concentrates, and tissue processing kits (RNA/miRNA, DNA) for histopathology and molecular research applications. One-time purchase model per kit/container with recurring revenue from consumables.
2. PAXgene Blood Collection Products: Sale of blood collection tubes (RNA, DNA, ccfDNA variants), purification kits and accessories. IVD and RUO variants available. Sold through QIAGEN distribution network.
3. PAXgene Urine Liquid Biopsy Products: Sale of urine cfDNA stabilization and collection products for liquid biopsy research applications, including the PAXgene Urine Liquid Biopsy Set (RUO).
4. Strategic Partnership Products: Products developed through strategic alliance with QIAGEN and BD for standardized urine liquid biopsy solutions targeting non-invasive cell-free DNA analysis.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels5 records

Core offering

PreAnalytiX manufactures and sells the PAXgene product line of preanalytical specimen collection and processing systems that integrate and standardize the collection, transport, storage, stabilization and purification of nucleic acids (RNA, miRNA, DNA, ccfDNA, proteins) from human specimens including blood, urine, saliva, tissue, and bone marrow for molecular diagnostic testing and clinical research. The portfolio includes specialized blood collection tubes, formalin-free tissue fixation and stabilization reagents, a urine liquid biopsy set, saliva DNA collectors, bone marrow RNA tubes, and配套 nucleic acid isolation kits designed to interoperate with QIAGEN purification platforms.

Product overview

PreAnalytiX is a Swiss manufacturer (Hombrechtikon, Switzerland) offering the PAXgene product line—a comprehensive preanalytical specimen collection and processing system. The portfolio consists of specialized products across five sample types: Blood (RNA, miRNA, DNA, ccfDNA collection tubes and purification kits), Urine (liquid biopsy set for cfDNA), Saliva (DNA collector), Tissue (formalin-free fixation and stabilization system with associated RNA/DNA kits), and Bone Marrow (RNA tubes and kits). The PAXgene Tissue System represents a formalin-free alternative to traditional histology, enabling simultaneous preservation of tissue morphology and biomolecules for downstream molecular analysis. Many blood products are designed for use on QIAGEN's QIAsymphony automated platforms. The company operates as a joint venture among PreAnalytiX GmbH, QIAGEN, and BD (Becton, Dickinson and Company).

Differentiator

Problem solved

Functional benefit

Products and services

• PAXgene Blood RNA Tube (IVD) Pre-filled blood collection tube for isolation of total RNA, including miRNA, from whole blood, designed for in vitro diagnostic use.
• PAXgene Blood RNA Kit (IVD) FDA
• PAXgene 96 Blood RNA Kit
• QIAsymphony PAXgene Blood RNA Kit
• PAXgene Blood miRNA Kit
• PAXgene Blood DNA Tube (IVD)
• PAXgene Blood DNA Tube
• PAXgene Blood DNA Kit
• PAXgene Blood ccfDNA Tube (RUO)
• QIAsymphony PAXgene Blood ccfDNA Kit
• PAXgene Urine Liquid Biopsy Set (RUO)
• PAXgene Saliva Collector (MBA)
• PAXgene Tissue FIX Container
• PAXgene Tissue STABILIZER Concentrate
• PAXgene Tissue RNA/miRNA Kit
• PAXgene Tissue DNA Kit
• PAXgene Bone Marrow RNA Tube
• PAXgene Bone Marrow RNA Kit

Quantifiable outcome

• Blood samples can be stored for up to 7 days at room temperature in PAXgene Blood ccfDNA Tubes with results comparable to immediately processed EDTA samples
• +2 more outcomes

Named customers2 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

Feature4 records

Partnerships

Two partnerships are on record, tiered core.

• QIAGEN N.V.coreStrategic or Co-development Partner · 1 September 2024PreAnalytiX, a joint venture company involving QIAGEN and BD, formed a strategic alliance in September 2024 to develop standardized urine liquid biopsy solutions for non-invasive cell-free DNA analysis. QIAGEN handles global distribution through its webshop and sales network. Products are sold under the PAXgene brand with integrated purification kits designed for QIAGEN platforms (QIAcube, QIAsymphony).
• Becton, Dickinson and Company (BD)coreStrategic or Co-development Partner · 1 September 2024BD partnered with PreAnalytiX and QIAGEN in September 2024 to develop standardized urine liquid biopsy solutions. BD contributes collection device technology and global medical device distribution capabilities. PreAnalytiX is the joint manufacturing entity for PAXgene products with both QIAGEN and BD involvement. BD registered trademarks appear alongside PreAnalytiX marks on the website footer.

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Zymo Research: US-based company specializing in nucleic acid sample collection, stabilization (e.g., DNA/RNA Shield), and purification products. Competes with PAXgene in collection-to-purification workflows for genomics and liquid biopsy applications.
• Streck: US-based manufacturer of blood collection tubes and stabilization products for molecular diagnostics and cell-free DNA, including Cell-Free DNA BCT and other preanalytical products that directly compete with PAXgene Blood ccfDNA Tubes.
• Greiner Bio-One: Austrian/German manufacturer of vacuum blood collection tubes, cell culture products, and preanalytical consumables serving clinical diagnostics and life science research; directly overlaps with PAXgene's blood collection product line.
• Sarstedt: German manufacturer of blood collection systems, sample tubes, and laboratory consumables for clinical diagnostics and research, including specialized nucleic acid collection tubes that compete with PAXgene products.
• Macherey-Nagel: German manufacturer of nucleic acid purification kits, sample collection devices, and laboratory consumables, with NucleoSpin and other product lines overlapping PAXgene Blood and Tissue kits.

Emerging players

• Norgen Biotek: Canadian manufacturer of sample collection, preservation, and nucleic acid purification kits for clinical and research use, with overlapping product lines in cfDNA and liquid biopsy preanalytics.

Broad incumbents

• Bio-Techne: Life sciences tools company offering sample preparation kits, ExoDx liquid biopsy products, and diagnostic consumables that intersect with PAXgene's preanalytical workflow in molecular diagnostics and exosome/cfDNA research.
• Thermo Fisher Scientific: Global life sciences tools company offering a broad portfolio of sample collection, nucleic acid purification, and molecular diagnostics products that overlap with multiple PAXgene product lines across blood and tissue.
• Becton, Dickinson and Company (BD): Major medical device and life sciences company that is itself a JV partner in PreAnalytiX but also manufactures competing blood collection tubes, Vacutainer systems, and preanalytical products through its BD Life Sciences segment.
• QIAGEN N.V. JV partner and global leader in sample preparation, nucleic acid purification, and molecular diagnostics automation. Distributes PAXgene products but also offers competing purification kits and instruments that integrate with the PAXgene ecosystem.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/preanalytix-gmbh

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PreAnalytiX