Regenerative Medicine Institute

What Regenerative Medicine Institute does

RMI Health, operating under the legal entity RMI Investment Group, LLC (Montclair, New Jersey), is a physician-led regenerative medicine institute that delivers advanced cellular therapies at a licensed clinical facility in San José, Costa Rica. Its core technology combines umbilical cord-derived mesenchymal stem cells (UC-MSCs) and Multilineage-differentiating Stress-Enduring (MUSE) cells, processed in an in-house ISO 5 and ISO 7 certified laboratory with an 80%+ cell viability guarantee. RMI holds the only license in Costa Rica to produce and expand mesenchymal stem cells, granted under Decreto 39,986-S by the Costa Rican Ministry of Health — a regulatory position that permits high-dose protocols unavailable in FDA-restricted US settings.

The clinical offering is anchored by RMI's proprietary 3-Step Regenerative Protocol — Therapeutic Plasma Exchange to clear inflammatory molecules, high-volume UC-MSC infusion for immunomodulation, and MUSE cell administration for pluripotent-like reconstruction — and is delivered across five verticals: Longevity Medicine, Cognition & Neuroprotective Care, Orthopedics & Pain Management (including the Orthropic subchondral bone protocol), Sexual Wellness (Harmony for women, Enhance for men), and Regenerative Dermatology. Treatments are priced between $19,000 and $60,000+ per protocol on a quote-based, one-time license model, with bundled concierge medical tourism services (travel, 5-star partner hotels, ground transport, recovery support).

RMI serves high-net-worth international patients — including executives, biohackers, professional athletes, and individuals with chronic or autoimmune conditions — through a physician-led, sales-led GTM motion. Patient acquisition relies on high-profile testimonials, thought-leadership content, and a concierge intake process spanning eligibility review, medical onboarding, treatment at the Costa Rica facility, and structured multi-stage follow-up care. Across 15+ years, the clinic has treated 1,800+ patients, reports a 92% Net Promoter Score, and is co-founded by Nobel Prize nominee Dr. Vincent Giampapa, a recognized pioneer in anti-aging medicine.

Name

Regenerative Medicine Institute

Legal name

RMI Investment Group, LLC

Website

https://rmihealth.com

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

11–50 employees

Short description

RMI Health is a physician-led regenerative medicine institute that delivers stem cell and MUSE cell therapies at a licensed facility in Costa Rica, serving international high-net-worth patients across longevity, orthopedics, cognition, sexual wellness, and dermatology via a concierge medical tourism model.

Ownership category

akta.pro rank

Product category

Regenerative Medicine

NAICS

Other Ambulatory Health Care Services (6219), Scientific Research and Development Services (5417)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011), Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

Stem Cell–Based Regenerative Therapies (HLAAAGAA)

akta.pro secondary industries

Stem Cell Therapies (MSC/iPSC/HSC-derived) (HLAAABAE), Regenerative Immunology & Inflammation Modulation (pro-regenerative biologics) (HLAAAGAL), Cartilage, Bone & Musculoskeletal Regeneration (HLAAAGAH), Medical Wellness & Longevity (Health Screening, Biohacking, Anti-aging Programs) (THAJAHAI), Medical Spas (Medi-Spa) (HSADAKAB)

Keywords

• Regenerative medicine services
• Stem cell therapy
• Longevity medicine
• Therapeutic plasma exchange
• Orthopedic regenerative treatment

Headquarters

HQ city

San José

HQ country

Costa Rica

HQ region

Latin America

Offices2 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Regenerative Medicine Treatments: Comprehensive regenerative treatments including stem cell therapy, therapeutic plasma exchange, and targeted injections for longevity, orthopedics, sexual wellness, and cognitive enhancement. Treatments are multi-day clinical protocols delivered at the Costa Rica facility with concierge support.
2. Bio-Insurance Services: Collection and cryopreservation of circulating stem cells after bone marrow pharmacologic stem cell mobilization for future therapeutic use.
3. Concierge Medical Tourism Services: Private coordination including travel arrangements, accommodation booking, airport transfers, and recovery support services bundled with treatment packages.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels6 records

Core offering

RMI Health delivers physician-led regenerative medicine treatments at its Costa Rica clinical facility, anchored by a proprietary 3-Step Regenerative Protocol that combines Therapeutic Plasma Exchange (TPE), high-volume umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions, and MUSE cell administration. The company offers treatment programs across Longevity Medicine, Cognitive and Neuroprotective Care, Orthopedics and Pain Management, Sexual Wellness, and Regenerative Dermatology, with concierge support for travel, accommodation, and recovery.

Product overview

RMI Health operates as a physician-led regenerative medicine institute offering a structured portfolio of treatments centered around their proprietary 3-Step Regenerative Protocol. The core protocol combines Therapeutic Plasma Exchange (TPE) for biological environment preparation, umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions for immunomodulation, and MUSE cell administration for targeted tissue regeneration. Treatment programs span five primary categories: Longevity Medicine (including TPE, Bio-Insurance, and Stem Cell Infusions), Cognition & Neuroprotective Care, Orthopedics & Pain Management (Regenerative Orthopedics and Orthropic), Sexual Wellness (Harmony for females and Enhance for males), and Regenerative Dermatology (Face and Neck Treatments). All cellular preparation is performed in-house under ISO 5 and ISO 7 certifications.

Differentiator

Problem solved

Functional benefit

Brands

• RMI Health: Primary brand name for the physician-led regenerative medicine institute focused on structured evaluation, lab-grade control, and patient-specific clinical pathways.
• TPE – Therapeutic Plasma Exchange
• Bio-Insurance
• Stem Cell Infusions
• Harmony
• Enhance
• Orthropic
• Regenerative Orthopedics
• Face and Neck Treatments

Products and services

• Therapeutic Plasma Exchange (TPE) Therapeutic Plasma Exchange that resets the bloodstream by removing inflammatory molecules, dysfunctional proteins, and circulating senescent factors and replacing them with clean plasma proteins such as albumin, creating a healthier internal environment for downstream regenerative interventions.
• Bio-Insurance Collection and cryopreservation of circulating stem cells after bone marrow pharmacologic stem cell mobilization with G-CSF, stored for future therapeutic use including emerging technologies such as partial cellular reprogramming ex-vivo.
• Stem Cell Infusions Intravenous delivery of umbilical cord-derived mesenchymal stem cells (UC-MSCs) and MUSE cells into the bloodstream to support cellular renewal, tissue repair, immune balance, and inflammation modulation as part of the regenerative protocol.
• Cognitive & Neuroprotective Care Guided by advanced imaging, patients receive a sequence of synchronised therapies that prepare the brain for autologous cell infusion, a non-surgical approach designed to improve memory, focus, mood, and overall cognitive vitality.
• Regenerative Orthopedics Regenerative orthopedic treatment using stem cell therapy to repair joints, reduce inflammation, and delay or prevent surgery for patients with chronic joint and orthopedic conditions.
• Orthropic

Quantifiable outcome

• 1800+ patients treated successfully with advanced regenerative therapies
• +4 more outcomes

Named customers6 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

Feature4 records

Partnerships

Three partnerships are on record, tiered core and minor.

• Regenesis LabscoreStrategic or Co-development PartnerPartnership with Regenesis Labs for enhanced quality oversight and GMP certification support. Regenesis Labs is currently pursuing GMP (Good Manufacturing Practice) certification, providing additional regulatory validation of RMI's laboratory processes and cell preparation standards.
• Partner HotelsminorOthersRelationships with 5-star partner hotels for patient accommodation during treatment protocols. Concierge services coordinate recovery stays at vetted hospitality partners, providing seamless patient experience throughout the treatment journey.
• Local Costa Rican HospitalscoreImplementation/ SI/ Consulting PartnerLocal partnerships with Costa Rican medical facilities for comprehensive patient care, including hospital access for emergency situations and advanced diagnostic capabilities. Supports the medical tourism ecosystem in Costa Rica.

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• BioXcellerator: Stem cell clinic operating in Colombia with similar umbilical cord-derived MSC and exosome offerings, directly competing for international medical-tourism patients seeking regenerative therapies.
• Regenexx: US-based regenerative orthopedic network specializing in image-guided stem cell injections for joints and spine; competes most directly in RMI's orthopedic and pain management indication.
• INFUSIO: Multi-location regenerative medicine clinic offering stem cell and exosome therapies in the US and Germany for longevity and chronic conditions; comparable in treatment scope and premium positioning.
• DVC Stem: Grand Cayman-based stem cell therapy clinic using umbilical cord-derived MSCs for anti-aging and regenerative use cases; competes for the same affluent international patient demographic.
• Swiss Medica: International regenerative medicine clinic offering stem cell therapies in Switzerland and Serbia for longevity and chronic disease indications, attracting similar high-net-worth medical-tourism clientele.
• Celltex Therapeutics: US-based autologous MSC therapy provider with Mexico clinical operations; competes directly in the high-dose stem cell therapy market targeting anti-aging and orthopedic patients.
• U.S. Stem Cell: US stem cell clinic offering autologous and allogeneic cell therapies across orthopedic and systemic indications; competes in the same regenerative treatment category.

Emerging players

• AgeRejuvenation: US-based longevity and regenerative therapy provider focusing on hormone optimization and cell-based treatments; partial overlap with RMI's longevity segment.
• Viability Sciences (formerly Regenesis Labs partner ecosystem): Stem cell lab and clinical services provider pursuing GMP certification; RMI's named GMP partner and adjacent capability in cell processing and quality systems.

Regional players

• Clínica Universidad Católica / Costa Rica Medical Tourism Ecosystem: Broader Costa Rican hospital/medical-tourism ecosystem where RMI operates; relevant comparables for facility-based premium medical services catering to international patients in the same geography.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/RMI_Costa_Rica
• Facebookfacebook.com/RMI.Health
• LinkedInlinkedin.com/company/rmi-international
• Instagraminstagram.com/rmi.health

Compliance5 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Regenerative Medicine Institute