Longevity Science Foundation

What Longevity Science Foundation does

The Longevity Science Foundation (LSF) is a 501(c)(3) nonprofit foundation established in November 2021 in Zug, Switzerland and incorporated in Miami, Florida in February 2022, with U.S. tax-exempt status granted in August 2022. The foundation's core activity is catalytic grantmaking for early-stage research in human longevity and chronic disease prevention, with grant sizes up to $200,000 per project allocated across four focus areas: Therapeutics, Personalized Medicine, Artificial Intelligence, and Predictive Diagnostics. LSF operates a three-stage scientific review process (Letter of Intent, full proposal review, and Scientific Advisory Board evaluation) and currently funds three active research projects at the University of Oxford, University of Copenhagen, and the Healthy Longevity Medicine Society, with 31 additional projects in its pipeline.

LSF's revenue model is entirely philanthropic, relying on individual donations, corporate partnerships, and campaign-based fundraising, with the stated commitment that 100% of donations go directly to research and operating costs are funded separately. The foundation runs a five-tier donor program ranging from "LSF Ally" (any amount) to "LSF Founders Fund" ($500,000+), with the top tier offering co-investment rights alongside LongeVC. Donations are accepted via cash, wire, donor-advised funds, appreciated securities, cryptocurrency (through The Giving Block), QCD from IRAs, and bequests. The foundation differentiates itself through the credibility of its Scientific Advisory Board (including Nobel laureate Michael Levitt) and its strategic integration with LongeVC, which was co-founded by overlapping leadership.

The foundation's primary stakeholders are: (1) academic researchers and research institutions applying for catalytic early-stage funding; (2) individual donors and philanthropists seeking tax-efficient vehicles to engage with longevity science, including the prospect of commercial co-investment rights on grantee spinouts; (3) women and the general public concerned with healthy aging and chronic disease prevention; and (4) strategic partners across the longevity ecosystem (academic institutions, medical societies, longevity-focused VCs, and corporate sponsors). LSF pursues a community-led, event-driven go-to-market approach anchored by the annual Longevity Science Summit (120 attendees at inaugural 2025 event in Miami), educational content series ("Hype vs. Reality," "Spotlight"), and themed campaigns such as the "Invested in Her" initiative targeting women's health and ovarian aging ($250,000 goal by September 2026).

Name

Longevity Science Foundation

Legal name

Longevity Science Foundation

Website

https://longevity.foundation

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

11–50 employees

Short description

The Longevity Science Foundation is a 501(c)(3) nonprofit that funds early-stage research on healthy aging and chronic disease prevention through grants of up to $200,000 per project, serving academic researchers, individual donors, and the global longevity ecosystem.

Ownership category

akta.pro rank

Product category

Longevity Research Philanthropy

NAICS

Voluntary Health Organizations (813212), Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Research & Science Grantmaking Foundations (BPAGAKAI)

akta.pro secondary industry

Health & Medical Research Grantmaking Foundations (BPAGAKAL)

Keywords

• Longevity research funding
• Biomedical grant programs
• Healthspan extension research
• Preventive medicine philanthropy
• Aging science grants

Headquarters

HQ city

Miami

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Operations, Personnel, Marketing or Sales, Others

Revenue model

1. Individual Donations: Tax-deductible donations from individuals at various giving levels. 100% of donations go directly to research; operating costs are funded separately. Accepted via cash/wire, DAF, appreciated securities, cryptocurrency, QCD from IRAs, and bequests.
2. Corporate & Institutional Grants: Corporate partnerships and institutional funding for specific research initiatives. LSF Founders Fund ($500K+) offers named grant calls, first investment rights into spinouts, and co-investment alongside LongeVC.
3. Campaign-Specific Fundraising: Time-limited campaigns like 'Invested in Her' targeting women's health and menopause research ($250,000 goal by September 2026), with partner match incentives (e.g., LongeVC contributing additional $25,000).

Pricing tiers

Go-to-market motion2 records

Distribution channels5 records

Marketing channels9 records

Core offering

The Longevity Science Foundation (LSF) is a 501(c)(3) nonprofit foundation that funds early-stage scientific research aimed at preventing chronic and age-related diseases and extending the healthy human lifespan. It awards research grants of up to $200,000 per project to academic institutions across four focus areas: Therapeutics, Personalized Medicine, Artificial Intelligence, and Predictive Diagnostics. The foundation also operates donor engagement programs, educational content (Hype vs. Reality series, Spotlight publications), and convening events such as the annual Longevity Science Summit.

Product overview

The Longevity Science Foundation is a nonprofit organization that does not offer commercial products or services. Its primary activities include funding early-stage longevity research through grant programs, providing educational content on longevity science, and facilitating donations for research initiatives. The Foundation funds research across areas including female fertility and longevity, brain aging, heart aging, and other age-related diseases through grant awards typically up to $200,000 per project.

Differentiator

Problem solved

Functional benefit

Products and services

• Research Grant Program Core three-stage grant program (Letter of Intent, full proposal, Scientific Advisory Board evaluation) awarding up to $200,000 per project to academic researchers and institutions conducting early-stage R&D in human longevity and chronic disease prevention. Funds are disbursed in installments over multi-year project durations.
• Female Fertility & Longevity Grant Call Targeted funding call for innovative scientific proposals on ovarian aging, oocyte preservation, hormonal/genetic interventions, and lifestyle/environmental factors affecting fertility decline. Awards up to $200,000 per selected project and addresses the most underfunded areas in medicine affecting hundreds of millions of women globally.
• Invested in Her Campaign Time-limited campaign targeting women's health and menopause research with a $250,000 fundraising goal by September 1, 2026. Includes a three-pillar research portfolio covering Measurement (menopause clock, molecular sensors), Biology (mechanisms linking reproductive aging to systemic decline), and Intervention (gene therapy, epigenetic reprogramming). Features matching partner LongeVC contributing an additional $25,000.
• Multi-Tiered Donor Recognition Program Structured donor engagement program with five giving tiers ranging from LSF Ally ($0+) to LSF Founders Fund ($500K+). Each tier offers escalating benefits including tax-deductible donations, quarterly research updates, lab visits, observer seats at grant reviews, named grant calls, co-investment rights alongside LongeVC, and summit panel participation. 100% of donations flow directly to research with operating costs funded separately.

Quantifiable outcome

• Women with early menopause face ~2x higher mortality risk vs typical timing
• +5 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

13 partnerships are on record, tiered secondary, core and minor.

• International Longevity Alliance (ILA)secondaryStrategic or Co-development Partner · 1 October 2023Global nonprofit uniting longevity groups from 50+ countries; supports aging research, fosters networking, enhances geroprotective tech regulation, and educates public on science-based life extension.
• European Society of Preventive Medicine (ESPM)coreStrategic or Co-development Partner · 9 July 2023Global Fellowship committed to promoting health and well-being through prevention of diseases; LSF and ESPM work together on new educational initiatives and opportunities; ESPM's focus on prevention aligns with LSF's mission.
• King's College London (KCL)coreStrategic or Co-development Partner · 14 February 2022First academic partner of LSF; collaboration with ARK (Ageing Research at King's) on research and educational efforts focused on ageing, psychedelics, and mental health treatments; synergizes with 2022 funding call for projects in these areas.
• Healthy Longevity Medicine Society (HLMS)coreStrategic or Co-development PartnerInternational longevity medical society; LSF played pivotal role in HLMS establishment and ongoing support; President and VP of HLMS serve on LSF Scientific Advisory Board, creating deep integration.
• Healthspan Action Coalition (HSAC)secondaryStrategic or Co-development PartnerUS 501(c)(3) nonprofit working towards global societal movement supporting healthy aging; promotes favorable policy and funding for scientific research, innovations and patient engagement.
• The Giving BlockcoreTechnology or IntegrationLeading platform enabling nonprofits to accept cryptocurrency and other donations; processes crypto donations (100+ currencies), stock donations, and DAF grants securely for LSF with automatic tax receipts.
• Clear (Water Purification)minorGTM or Marketing PartnerOfficial Water Purification Sponsor; water quality company redefining purification in real estate; demonstrates LSF's corporate sponsorship network for events and campaigns.
• Miami Downtown Development AuthoritysecondaryGTM or Marketing PartnerSupporting partner for Longevity Science Summit 2025; helps position Miami as hub for longevity sciences in the US; provides venue and local support for events.
• Baptist Health Concierge MedicineminorGTM or Marketing PartnerSponsor and speaker at Longevity Science Summit; concierge medicine practice specializing in preventive care and longevity; Dr. Ravindra Ganesh speaks at events.
• Muhdo HealthminorGTM or Marketing PartnerSponsor for Longevity Science Summit; provides biological age testing for Research Builder donor tier ($10K+); offers discounted epigenetic age assessment.
• Bean Intellisphere GroupminorGTM or Marketing PartnerSponsor for Longevity Science Summit 2025; part of the supporting companies ecosystem for the event.
• University of CopenhagencoreStrategic or Co-development PartnerGrant recipient for 'Rejuvenating the Aging Brain' study led by Dr. Morten Scheibye-Knudsen; 3-year study beginning 2025 using AI-driven compound screening to eliminate senescent brain cells.
• University of OxfordcoreStrategic or Co-development PartnerGrant recipient for 'Metabolic Mechanisms of Aging in the Heart' study led by Prof. Pawel Swietach; 3-year study beginning 2024 on diet-related methylation changes and cardiac aging; collaboration with ARK at King's College London.

Scale indicators14 records

Recent moves10 records

Expansion highlights6 records

Emerging players

• Impetus Grants: Impetus Grants is a nonprofit funding platform that vets and recommends high-impact nonprofits to donors, including health and aging causes. Comparable as a donor-routing infrastructure in the longevity philanthropy space that competes for the same HNW donor segment.
• Buck Institute for Research on Aging: Buck Institute is a leading independent biomedical research institute focused on aging, whose president Eric Verdin sits on LSF's Scientific Advisory Board. It is partly comparable as both a research performer and a recipient of philanthropic funding in the same field.
• Life Extension Advocacy Foundation (LEAF): LEAF is a US 501(c)(3) nonprofit supporting longevity research through donations to academic labs and public education. Smaller-scale emerging peer operating with a similar nonprofit-grantmaking-plus-advocacy model.
• Longevity Impact Fund: Longevity Impact Fund is a smaller grantmaker focused on translating aging research into clinical applications, with overlapping mission in healthy longevity and chronic disease prevention. It is a smaller emerging peer in the same catalytic-grant niche.

Direct peers

• American Federation for Aging Research (AFAR): AFAR is a US nonprofit providing individual grants and postdoctoral fellowships to researchers in aging biology and clinical geriatrics. It is a direct competitor for donor mindshare and for academic grantees in the same translational longevity space.
• SENS Research Foundation: SENS Research Foundation funds and conducts research into the seven hallmarks of aging and operates a research center in Mountain View. As a longevity-focused research nonprofit with a grantmaking component, it is a direct peer competing for both donors and scientific credibility.
• Glenn Foundation for Medical Research: Glenn Foundation funds basic research on the biology of aging through grants to academic institutions and co-funds the Glenn Center for Aging Research at multiple universities. Direct peer in academic longevity grantmaking with established university relationships.
• Methuselah Foundation: Methuselah Foundation is a US-based nonprofit funding regenerative medicine and longevity research through prizes, grants, and investments. It shares LSF's model of catalytic grantmaking plus venture-style spinout support (via Methuselah Fund) and directly competes for longevity-focused donor attention.

Broad incumbents

• Hevolution Foundation: Hevolution is a Saudi-backed nonprofit committing roughly $1B/year to aging and longevity research, offering grants and operating funds to academic and biotech projects. It is the dominant incumbent in the same grantmaking space LSF occupies, but at vastly greater scale and with a global mandate.
• Wellcome Trust: Wellcome Trust is a large UK-based charitable foundation funding biomedical research and public health globally. It is a broad incumbent in science philanthropy, with an increasingly active portfolio in aging-relevant research that competes for similar institutional donor dollars.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xtwitter.com/longescience
• Facebookfacebook.com/Longevity-Science-Foundation-104037182049933
• LinkedInlinkedin.com/company/longevity-science-foundation

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Longevity Science Foundation