Tymora Analytical Operations
Tymora Analytical Operations is a Purdue University spinout R&D laboratory that develops proprietary nanopolymer-based products and contract research services for non-invasive biomarker discovery using extracellular vesicle proteomics and phosphoproteomics, serving academic researchers, CROs, and pharmaceutical and biotechnology companies worldwide.
- Company typePrivate
- Founded2011
- HeadquartersWest Lafayette, United States
- Headcount1–10
- GTM typeB2B
- OfferingServices
What Tymora Analytical Operations does
Tymora Analytical Operations is a Purdue University spinout founded in 2010–2011 in West Lafayette, Indiana, operating as a small R&D laboratory (1–10 employees) specializing in non-invasive biomarker discovery for cancer, Parkinson's, Alzheimer's, and other diseases. The company's technical core is built around three proprietary nanopolymer-based platforms: EVtrap (Extracellular Vesicles Total Recovery and Purification) for isolating extracellular vesicles from minute biofluid volumes without antibodies, pIMAGO — a universal non-antibody phosphoprotein detection reagent based on multifunctionalized dendrimers with Ti(IV) ions, available in Western Blot, ELISA/microplate, and microarray formats — and PolyMAC, a soluble nanopolymer for homogeneous phosphopeptide enrichment prior to mass spectrometry. Tymora combines this IP into two distinct revenue streams: (1) a research products catalog sold direct-to-consumer through the company's e-commerce storefront at unit prices ranging from $55 to $487, including pIMAGO kits, PolyMAC enrichment kits, avidin-fluorophore conjugates, control phosphoproteins, and optimized buffers/plates; and (2) a contract research services business offering EV-based proteomics and phosphoproteomics analysis from plasma, urine, saliva, tissue, cell lysate, and custom sample types for CROs, pharmaceutical, biotechnology, and academic clients. The company monetizes and validates its science through NIH and NSF SBIR/STTR grants (disclosed cumulative funding above $1.6M since 2012), foundation awards from the Michael J. Fox Foundation, peer-reviewed publications in PNAS, Nature Communications Medicine, and Molecular and Cellular Proteomics, and a global distributor network covering 14+ countries across Asia, Europe, and Oceania. Go-to-market is sales-led via direct engagement and technical support, supplemented by content marketing through scientific publications and conference presentations.
Tymora Analytical Operations firmographics
Firmographics- Name
- Tymora Analytical Operations
- Legal name
- Tymora Analytical Operations
- Website
- https://tymora-analytical.com
- Company type
- Private
- Founded year
- 2011
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- Tymora Analytical Operations is a Purdue University spinout R&D laboratory that develops proprietary nanopolymer-based products and contract research services for non-invasive biomarker discovery using extracellular vesicle proteomics and phosphoproteomics, serving academic researchers, CROs, and pharmaceutical and biotechnology companies worldwide.
- Ownership category
- akta.pro rank
Tymora Analytical Operations industry classification
Industry- Product category
- Proteomics & Biomarker Discovery Services
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), Testing Laboratories and Services (541380)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)
- akta.pro primary industry
- Proteomics & Mass Spectrometry Services (HLAGANAB)
- akta.pro secondary industries
- Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI), Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation) (HLAAAIAI)
Keywords
Where Tymora Analytical Operations is headquartered
LocationHeadquarters
- HQ city
- West Lafayette
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Tymora Analytical Operations business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Supply Chain, Marketing or Sales
Revenue model
- Research Products: Sale of phosphoprotein detection and phosphopeptide enrichment products including pIMAGO kits (Western Blot and ELISA formats) and PolyMAC enrichment kits. Products sold directly through website with pricing from $60 to $487.
- Contract Research Services: Proteomics contract services including plasma, urine, saliva, and tissue EV proteomics/phosphoproteomics analysis. Services offered to CROs, pharmaceutical companies, and research scientists for biomarker discovery and drug development.
- Custom Proteomic Analysis: Custom analysis services for diverse sample types including plant, fungi, bacteria proteomics, IP samples, and in-gel digests for research institutions requiring specialized analysis.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | pIMAGO HRP Detection on Western Blot complete kit |
| Unit Pricing | Pay-as-you-go | Spin-Tip PolyMAC-Ti Phosphopeptide Enrichment Kit |
| Unit Pricing | Pay-as-you-go | pIMAGO HRP Colorimetric Detection on Microplate (ELISA) |
| Unit Pricing | Pay-as-you-go | Avidin-Fluor detection reagents |
| Unit Pricing | Pay-as-you-go | Control Phosphoprotein for Western Blot |
| Unit Pricing | Pay-as-you-go | Supplementary products (blocking buffer, binding buffer, plates) |
Go-to-market motion1 record
Distribution channels3 records
Marketing channels5 records
Tymora Analytical Operations product offering
Product offeringCore offering
Tymora Analytical Operations is an R&D laboratory that develops and sells proprietary phosphoproteomics reagents (pIMAGO detection kits and PolyMAC enrichment kits) and provides contract research services for non-invasive biomarker discovery. The company analyzes extracellular vesicles (EVs) and post-translational modifications from biofluids such as plasma, urine, saliva, and tissue, using proprietary EVtrap, pIMAGO, and PolyMAC nanopolymer technologies combined with LC-MS/MS.
Product overview
Tymora Analytical Operations offers two core technology platforms: pIMAGO and PolyMAC, supported by EVtrap services. pIMAGO is a universal non-antibody phosphoprotein detection reagent based on multifunctionalized nanopolymers (dendrimers) available for Western Blot, ELISA/microplate, and microarray formats. PolyMAC is a metal-ion functionalized soluble nanopolymer for phosphopeptide enrichment prior to mass spectrometry. Both products are supported by supplementary reagents including avidin conjugates, blocking buffers, binding buffers, control phosphoproteins, and 96-well plates. The company also provides contract proteomics services using EVtrap technology for biomarker discovery from plasma, urine, saliva, tissue, and cell lysate samples, routinely identifying 600-1,200+ unique proteins from microliter-scale sample volumes.
Differentiator
Problem solved
Functional benefit
Products and services
- pIMAGO Phosphoprotein Detection Universal non-antibody phosphoprotein detection reagent based on water-soluble, globular nanopolymers (dendrimers) functionalized with Ti(IV) ions for phosphate group recognition. Available as kits for Western Blot (HRP or Fluor 550/680/800 detection) and ELISA/microplate (HRP or Fluor 550/680/800 detection) formats. Sold to academic and industry research scientists conducting protein phosphorylation studies.
- PolyMAC Phosphopeptide Enrichment Metal-ion functionalized soluble nanopolymer for homogeneous phosphopeptide enrichment prior to mass spectrometry analysis. Sold as a Spin-Tip PolyMAC-Ti Phosphopeptide Enrichment Kit (48 or 96 enrichments). Used by mass spectrometry labs for phosphoproteomics sample preparation with high reproducibility, selectivity, and recovery.
- Plasma Proteomics/PTMs Services LC-MS/MS analysis services including plasma EV proteomics, plasma EV phosphoproteomics, plasma EV glycoproteomics, and other plasma EV PTM analyses using the EVtrap method. Can identify more than 1,000 unique proteins from 10 uL plasma or 600-1,000 unique phosphoproteins from 0.5 mL plasma. Offered to pharmaceutical, biotech, and academic clients.
- Urine Proteomics/PTMs Services LC-MS/MS analysis services including urine EV proteomics, urine EV phosphoproteomics, urine EV glycoproteomics, and other urine EV PTM analyses using the EVtrap method. Can identify more than 1,200 unique proteins from 0.2 mL urine or 800-1,000 unique phosphoproteins from 10 mL urine. Offered to pharmaceutical, biotech, and academic clients.
- Saliva Proteomics/PTMs Services LC-MS/MS analysis services including saliva EV proteomics, saliva EV phosphoproteomics, saliva EV glycoproteomics, and other saliva EV PTM analyses using the EVtrap method. Can identify more than 1,000 unique proteins from 20 uL saliva or 500-1,000 unique phosphoproteins from 1 mL saliva. Offered to pharmaceutical, biotech, and academic clients.
- Tissue Proteomics/PTMs Services LC-MS/MS analysis services including tissue proteomics, tissue phosphoproteomics, tissue glycoproteomics, and other tissue PTM analyses for frozen tissue samples with optimized homogenization, protein extraction, lipid removal, and PolyMAC-based enrichment. Offered to pharmaceutical, biotech, and academic clients.
- Cell Lysate Proteomics Services Cell lysate analysis services including global proteome analysis, phosphoproteome analysis, glycoprotein analysis in cell lysates, LC-MS/MS analysis of low abundant proteins, and other PTM analysis from frozen cells or cell lysate samples. Offered to pharmaceutical, biotech, and academic clients.
- Custom Proteomic Analysis Services Custom proteomic services for diverse sample types including plant proteomics/phosphoproteomics, fungi proteomics/PTMs, bacteria proteomics/PTMs, IP sample analysis, in-gel digests, and tailored analysis for plant and bacterial samples. Offered to research institutions requiring specialized analysis.
Quantifiable outcome
- Identifies over 1,000 unique proteins from just 0.01 mL plasma or 0.2 mL urine
- +3 more outcomes
Companies that use Tymora Analytical Operations
Customer profileNamed customers3 records
Segments1 record
Ideal customer profiles3 records
Tymora Analytical Operations technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
Tymora Analytical Operations partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered minor and core.
- Johns HopkinsminorCollaboration to investigate brain EVs and organoids for Alzheimer's disease diagnosis and treatment research using mini brain-like structures.
- Purdue University (Dr. W. Andy Tao lab)coreCollaborative research with Purdue University professor W. Andy Tao (CSO of Tymora) pioneering liquid biopsy methods for measuring drug response based on metabolizing proteins in circulating EVs.
- St. Jude Children's Research HospitalcoreCollaborative study to detect drug response using plasma EVs, with article published in PNAS Nexus titled 'Monitoring drug metabolic pathways through extracellular vesicles in mouse plasma.'
- Integrated Micro-Chromatography Systems (IMCS)corePartnership between IMCS (a leader in automating laboratory workflows) and Tymora Analytical (authority in exosome purification and proteomics services) to advance exosome research through workflow integration and streamlining capabilities.
Scale indicators5 records
Recent moves6 records
Expansion highlights5 records
Tymora Analytical Operations competitors and assessment
Company assessmentEmerging players
- System Biosciences (SBI): EV isolation and exosome research reagent provider. Competes with Tymora's EVtrap in supplying EV purification tools for biomarker and translational research.
- NanoString Technologies (Bruker Spatial Biology): Specialized proteomics and spatial omics platform, including nCounter and GeoMx workflows for protein/RNA profiling. Comparable as a mid-sized omics platform with research-use proteomics overlap.
- MBL International: Japanese reagent supplier with exosome/EV research tools and immunoassay kits. Comparable niche EV reagent and assay catalogue to Tymora's reagents portfolio.
Broad incumbents
- MilliporeSigma (Merck KGaA Life Science): Large proteomics reagent and analytical chemistry supplier, including phosphopeptide enrichment tools and immunoassay reagents. Incumbent competitor in the phosphoprotein detection and enrichment space.
- Cell Signaling Technology: Major provider of phospho-specific antibodies and reagents for Western Blot and ELISA. Competes in the phosphoprotein detection market that pIMAGO addresses, with a much larger reagent catalog.
- Promega Corporation: Provider of proteomics and sample-prep reagents, including mass spec-compatible phosphopeptide enrichment and ELISA tools. Comparable in product categories that overlap with PolyMAC and pIMAGO workflows.
- Bio-Techne: Life sciences tools company offering proteomics reagents, ELISA kits, and exosome diagnostics (via Exosome Diagnostics). Overlaps with Tymora across phosphoprotein detection and EV-based biomarker workflows.
Direct peers
- SomaLogic: Proteomics platform (SomaScan) for large-scale biomarker discovery from biofluids. Comparable to Tymora in offering non-invasive, high-multiplex proteomic measurements for research and translational use.
- Olink Holding: Proximity Extension Assay-based proteomics platform for biomarker discovery across plasma and other biofluids. Comparable proteomics technology category and customer base to Tymora.
- Biognosys: Contract proteomics and phosphoproteomics services provider using mass spec workflows. Closely comparable to Tymora's EV phosphoproteomics services for biomarker discovery.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights6 records
Customer concentration
Tymora Analytical Operations financial estimates
Financial estimateRevenue estimate
Valuation estimate
Tymora Analytical Operations leadership team
Management profileNumber of profiles
Profiles2 records
Tymora Analytical Operations funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Tymora Analytical Operations M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Tymora Analytical Operations
What does Tymora Analytical Operations do?
Tymora Analytical Operations is an R&D laboratory that develops and sells proprietary phosphoproteomics reagents (pIMAGO detection kits and PolyMAC enrichment kits) and provides contract research services for non-invasive biomarker discovery. The company analyzes extracellular vesicles (EVs) and post-translational modifications from biofluids such as plasma, urine, saliva, and tissue, using proprietary EVtrap, pIMAGO, and PolyMAC nanopolymer technologies combined with LC-MS/MS.
Is Tymora Analytical Operations a public or private company?
Tymora Analytical Operations is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Tymora Analytical Operations founded?
Tymora Analytical Operations was founded in 2011. It employs 1 to 10 people.
Where is Tymora Analytical Operations based?
Tymora Analytical Operations is headquartered in West Lafayette, United States, in the North America region.
How does Tymora Analytical Operations make money?
Three revenue lines are on record. Research Products are the primary driver. The others are contract Research Services and custom Proteomic Analysis.
Who are Tymora Analytical Operations's main competitors?
Emerging players on record are System Biosciences (SBI), NanoString Technologies (Bruker Spatial Biology) and MBL International. Broad incumbents are MilliporeSigma (Merck KGaA Life Science), Cell Signaling Technology, Promega Corporation and Bio-Techne. Direct peers are SomaLogic, Olink Holding and Biognosys.
Does Tymora Analytical Operations have an API?
No public API is recorded for Tymora Analytical Operations.
What industry is Tymora Analytical Operations in?
Tymora Analytical Operations's product category is Proteomics & Biomarker Discovery Services. Its primary akta.pro industry code is HLAGANAB, Proteomics & Mass Spectrometry Services, with a secondary code of HLAGAIAI, Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes). Its NAICS code is 541714 and its SIC code is 8731.