Soluzioni Informatiche

What Soluzioni Informatiche does

S-IN Soluzioni Informatiche S.r.l. is an Italian scientific data and informatics consultancy headquartered in Brescia, operating across pharmaceutical, chemical, cosmetics, food & feed, and agrochemical industries. The company is organized around two service brands: S-IN, which delivers cheminformatics, lab informatics, and KNIME-based workflow automation services; and TOXIT, a dedicated computational toxicology department providing in silico risk and safety assessment using QSAR, rule-based expert (SAR), and read-across methodologies compliant with OECD principles and EU regulations including REACH, CLP, EFSA guidance, and Cosmetics Regulation 1223/2009.

The technical stack combines proprietary TOXIT modeling capabilities with distribution and integration partnerships for third-party platforms, notably ACD/Labs (Spectrus, Percepta, ChemSketch), Dassault Systèmes BIOVIA Unified Lab Suite, Sartorius Umetrics Suite (SIMCA, MODDE), KNIME, Gaussian, Wave, and (effective January 2025) Advance/NanoLabo. S-IN acts as Italian distributor and system integrator for these vendors, delivering configured solutions for ELN, LIMS-adjacent data management, compound registration, multivariate analytics, and computational materials simulation.

Revenue is generated through four streams: tailored consulting services, contract research engagements, software distribution and integration (licensing/resale of third-party platforms), and corporate training delivered jointly with Sartorius Stedim Data Analytics. Pricing is project-based and not publicly disclosed. The customer base is enterprise B2B, concentrated in Italy/EMEA, with Chiesi Farmaceutici cited as a named reference. The company participates in EU-funded research projects with EFSA, ECHA, and JRC, providing both revenue and regulatory credibility. S-IN is a privately held Italian S.r.l. with 11-50 employees and no disclosed external investment, M&A, or funding events.

Name

Soluzioni Informatiche

Legal name

S-IN Soluzioni Informatiche S.r.l.

Website

https://s-in.it

Company type

Private

Founded year

1994

Operating status

Operating

Headcount range

11–50 employees

Short description

S-IN Soluzioni Informatiche is an Italian cheminformatics and computational toxicology consultancy serving pharmaceutical, chemical, cosmetics, and food companies in Italy and EMEA, combining proprietary in silico modeling with distribution and integration of third-party scientific software platforms.

Ownership category

akta.pro rank

Product category

Cheminformatics and Computational Toxicology Services

NAICS

Computer Systems Design and Related Services (54151), Analytical Laboratory Instrument Manufacturing (334516)

SIC

Services-Commercial Physical & Biological Research (8731), Laboratory Analytical Instruments (3826)

akta.pro primary industry

In Silico / Computational Toxicology & PK/PD Modeling (HLAGAFAM)

akta.pro secondary industries

AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO), Data Management, Biostatistics & Statistical Programming FSP (HLAGAOAB), DMPK / ADME & Bioanalysis (HLAGAFAC)

Keywords

• Cheminformatics consulting
• Computational toxicology services
• In silico predictions
• Laboratory informatics integration
• Scientific software distribution

Headquarters

HQ city

Vicenza

HQ country

Italy

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Consulting Services: Tailored consulting services for cheminformatics, scientific data analysis, digital transformation, and process optimization across chemical, pharmaceutical, agrochemical, food, and cosmetic industries.
2. Contract Research: Contract research services including in silico predictions, toxicological assessments, and computational toxicology services for regulatory compliance.
3. Software Distribution: Italian distribution and resale of specialized software including ACD/Labs solutions, Sartorius Umetrics Suite (SIMCA, MODDE, Easy Analytics), Dassault Systèmes BIOVIA, KNIME, Gaussian, and Advance/NanoLabo Simulation Software.
4. Training Services: Corporate training courses in Design of Experiments (DOE) and Multivariate Data Analysis in collaboration with Sartorius Stedim Data Analytics – Umetrics, offered in Italian for R&D, production, and quality control researchers.

Go-to-market motion1 record

Distribution channels6 records

Marketing channels3 records

Core offering

Soluzioni Informatiche (S-IN) is an Italian company that provides cheminformatics consulting, contract research, and in silico (Q)SAR-based toxicology prediction services for pharmaceutical, chemical, cosmetics, and food & feed companies. It operates a dedicated computational toxicology department (TOXIT) that delivers risk and safety assessments compliant with REACH, EFSA, and EU cosmetics regulations, and it serves as the Italian distributor and system integrator for life-science software platforms including ACD/Labs, Dassault Systèmes BIOVIA, Sartorius Umetrics Suite, KNIME, Gaussian, Wave, and Advance/NanoLabo.

Product overview

S-IN Soluzioni Informatiche is an Italian company offering a portfolio of cheminformatics, scientific consulting, and in silico services applied to chemical, toxicological, ecotoxicological, and environmental information across pharmaceutical, chemical, cosmetics, food, and other industries. The offering consists of three pillars: (1) Informatics & Cheminformatics Services including ADMS (Analytical Data Management System) consulting, LIMS, and KNIME-based workflow automation; (2) TOXIT Computational Toxicology Services providing QSAR, read-across, and rule-based expert model predictions for regulatory compliance; and (3) Software Distribution representing third-party platforms including ACD/Labs (Spectrus, Percepta, ChemSketch), Dassault Systèmes BIOVIA, Sartorius Umetrics Suite (SIMCA, MODDE, Easy Analytics), KNIME, Gaussian, Wave, and Advance/NanoLabo. The company operates as both a service provider and software distributor/system integrator, with industry-specific service packages for pharma, chemicals, cosmetics, food & feed, and other sectors. A training program in collaboration with Sartorius Umetrics provides courses on multivariate analysis and experimental design.

Differentiator

Problem solved

Functional benefit

Products and services

• Informatics & Cheminformatics Services Data science and cheminformatics consulting services combining analytical data management with informatics skills, covering LIMS configuration, BIOVIA Unified Lab Suite integration, KNIME-based workflow development, multivariate data analysis, design of experiments, and process optimization for regulated industries.
• TOXIT Computational Toxicology Services Specialized toxicological department delivering in silico risk and safety assessment for chemicals without in vivo or in vitro testing, using QSAR models, rule-based expert models (SAR), and read-across approaches compliant with OECD principles and applicable to REACH, pharmaceuticals, medical devices, cosmetics, food, plant protection, and biocides regulations.
• Pharma Industry Services Cheminformatics and toxicology services tailored for pharmaceutical R&D including computer-assisted structure elucidation (CASE), chromatographic method development, analytical chemistry informatics, molecular modeling, impurity characterization, and in silico toxicological evaluation of N-nitrosamines.
• Chemicals Industry Services Regulatory compliance services for chemical substances under REACH and CLP regulations, including Safety Data Sheet preparation, database and literature research, in silico predictions, genotoxicity impurities assessment, computer-assisted structure elucidation, chromatographic method development, and quality by design approaches.
• Cosmetics Industry Services Support for EU Regulation No. 1223/2009 compliance including eco-toxicological characterization of cosmetic ingredients, in silico toxicological assessment, database research, cosmetic label review, and Product Information File (PIF) documentation support.
• Food & Feed Industry Services Computational and cheminformatics solutions for food additives, flavorings, novel food, nutraceuticals, dietary supplements, and food contact materials, based on EFSA guidance, including database search, (Q)SAR predictions, read-across, and alert profiling for food-related substances.
• ACD/Labs Software Distribution Italian distribution of Advanced Chemistry Development, Inc. (ACD/Labs) solutions, including the Spectrus Platform for chemical structure and spectra management, Percepta for physicochemical and ADME predictions, and ChemSketch for molecular drawing and report generation, targeted at Italian life-science enterprises.
• Sartorius Umetrics Suite Distribution Italian distribution of the Sartorius Umetrics Suite including SIMCA for multivariate statistical analysis, MODDE for design of experiments, and Easy Analytics for process analytical technology, plus accompanying software implementation and system integration services.
• KNIME Implementation Services Software implementation and system integration services using KNIME Analytics Platform and KNIME Server for data mining, ETL, automated reporting, and compound property calculation workflows, including integrations with Oracle Database and OpenBabel.
• Gaussian Software Distribution Distribution of Gaussian computational chemistry software used for quantum chemistry calculations and molecular modeling in research and industrial applications.
• Wave Spectral Software Distribution Distribution of Wave spectral analysis software for processing NMR, IR, UV-Vis, and other spectroscopy data used in analytical laboratories.
• Advance/NanoLabo Simulation Software Distribution Official Italian distribution of AdvanceSoft Corporation's Advance/NanoLabo software for computational materials simulation, supporting materials modeling, ab initio calculations, molecular dynamics simulations of crystalline structures, surfaces, defects, nanostructured materials, and complex systems.
• Corporate Training Courses Remote corporate training courses in Design of Experiments and Multivariate Data Analysis offered in Italian in collaboration with Sartorius Stedim Data Analytics – Umetrics, with hands-on exercises using SIMCA and MODDE Pro, targeted at R&D, production, and quality control researchers in regulated industries.

Quantifiable outcome

• Approximately 50,000 compounds with calculated properties processed through automated KNIME workflow, with over 4 years of problem-free automated operation
• +1 more outcomes

Named customers1 record

Segments6 records

Ideal customer profiles1 record

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration10 records

AI capability7 records

Feature8 records

Partnerships

Ten partnerships are on record, tiered core, major and minor.

• ACD/Labs (Advanced Chemistry Development, Inc.)coreChannel Partner/ Reseller/ DistributorS-IN is the Italian distributor of ACD/Labs solutions including Spectrus Platform, Percepta (for physicochemical property calculations), and ChemSketch. This partnership enables provision of predictive tools for physicochemical, ADME, toxicology, and ecotoxicology properties of molecules to Italian life science companies.
• Dassault Systèmes BIOVIAcoreChannel Partner/ Reseller/ DistributorS-IN is a System Integrator of Dassault Systèmes BIOVIA, providing system configuration and integration services for BIOVIA's Unified Lab suite (Biovia One Lab), focusing on electronic laboratory notebook (ELN), procedure design and execution, and inventory management.
• Sartorius Stedim Data Analytics (Umetrics)coreChannel Partner/ Reseller/ DistributorS-IN distributes Sartorius Umetrics Suite (SIMCA, MODDE, Easy Analytics) in Italy and also provides software implementation and system integration services based on KNIME, R, and Python for data mining and data analysis problems.
• AdvanceSoft CorporationcoreChannel Partner/ Reseller/ DistributorEffective January 1, 2025, S-IN became an official distributor of Advance/NanoLabo Simulation Software for Italy. Advance/NanoLabo is advanced software for materials modeling, ab initio calculations, and molecular dynamics simulations designed to support complex studies through an intuitive graphical user interface.
• KNIMEcoreTechnology or IntegrationS-IN uses KNIME Analytics Platform and KNIME Server for workflow automation, data mining, and data analysis solutions. They build custom KNIME workflows for客户-specific applications including ETL processes, database integration, and automated reporting.
• Sartorius Stedim Data Analytics – UmetricsmajorStrategic or Co-development PartnerS-IN collaborates with Sartorius Stedim Data Analytics – Umetrics to provide corporate training courses in Design of Experiments (DOE) and Multivariate Data Analysis, targeting researchers in R&D, production, and quality control across regulated industries.
• EFSA (European Food Safety Authority)majorStrategic or Co-development PartnerS-IN's TOXIT department has participated in multiple EFSA funded projects including: Data collection for OpenFoodTox database (2012-2022), Further development of OpenFoodTox 3.0 (2023-2026), applicability of QSARs in TTC assessment, genotoxicity evaluation for pesticides, and expert assistance on EFSA's DCF Chemicals Data Catalogue.
• ECHA (European Chemicals Agency)majorStrategic or Co-development PartnerS-IN participated in ECHA funded project for data curation of the agency's systemic toxicity database, based on ESRs of the REACH registration database.
• JRC (Joint Research Centre)minorStrategic or Co-development PartnerS-IN participated in JRC funded projects including: Use of REACH registration database to calculate Human Health Effect Factors of USETox model, and Specific Advice on Exposure Assessment and Hazard/Risk Characterisation for Nanomaterials under REACH.
• EU Funded Projects (COSMOS)minorStrategic or Co-development PartnerS-IN participated in EU funded project COSMOS (Integrated In Silico Models for the Prediction of Human Repeated Dose Toxicity of Cosmetics).

Scale indicators2 records

Recent moves7 records

Expansion highlights4 records

Direct peers

• Simulations Plus: US-listed provider of in silico ADME/toxicology modeling software (GastroPlus, ADMETPredictor, MONOLIX) and contract research services for pharma and chemicals — closely overlapping S-IN's ACD/Labs Percepta-driven ADME/tox prediction and contract research business.
• MultiCASE: US-based vendor of QSAR/rule-based expert software for toxicity prediction (CASE Ultra). Direct competitor to TOXIT's rule-based expert models and QSAR services for regulatory submissions.
• Instem: UK-listed provider of life science informatics solutions (Provantis, LSS, Leadscope). Overlaps with S-IN's lab informatics/regulatory workflow capabilities, particularly for chemistry and toxicology data management.
• Lhasa Limited: UK-based not-for-profit providing in silico toxicology software (Vitic, Nexus, Derek) and contract research for regulated industries. Directly comparable to S-IN/TOXIT's QSAR, read-across, and rule-based toxicology offering.
• Molecular Networks (Altamira): German computational chemistry company offering cheminformatics software and contract research (NMR/MS prediction, retrosynthesis). Comparable to S-IN's cheminformatics consulting and software distribution business.

Others

• KNIME: Open-source data analytics/workflow platform used by S-IN to deliver automated cheminformatics and SDS mining workflows. Ecosystem partner/underlying platform rather than direct competitor, but KNIME's growing enterprise capabilities overlap with S-IN's implementation services.

Emerging players

• Scitara: Lab informatics integration platform (SciPace, SciConnect) focused on connecting lab instruments, ELN/LIMS, and informatics tools. Emerging competitor in the lab workflow automation space where S-IN also sells KNIME workflow services.

Broad incumbents

• ACD/Labs (Advanced Chemistry Development): Global cheminformatics software vendor (Spectrus, Percepta, ChemSketch). Both S-IN's distribution partner and a broad incumbent whose direct sales force competes with S-IN's local consulting and integration work.
• Dassault Systèmes BIOVIA: Broad lab informatics (ELN, LIMS, Unified Lab) and in silico chemistry suite from Dassault Systèmes. S-IN is a BIOVIA system integrator in Italy; BIOVIA itself competes broadly with the same customers in the same product category.
• Certara: US-listed biosimulation and regulatory science provider (Simcyp, Phoenix). Competes with S-IN/TOXIT in in silico ADME/tox prediction and regulatory submissions for pharma.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/s-in-soluzioni-informatiche

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Soluzioni Informatiche