UCSF Memory and Aging Center

What UCSF Memory and Aging Center does

The UCSF Memory and Aging Center (renamed the Edward and Pearl Fein Memory and Aging Center in 2025) is a clinical research center within the University of California, San Francisco that integrates patient care, translational research, and professional training focused on neurodegenerative diseases. Founded in 1998 by Bruce Miller, MD with co-founders Joel Kramer, PsyD, Kristine Yaffe, MD, and Rosalie Gearhart, RN, MSN, the center has grown from a single faculty member into a 300+ faculty/staff organization with 38 core faculty across neurology, geriatrics, psychiatry, cognitive psychology, neuroscience, and nursing. Its core clinical offerings include the Memory and Aging Center Clinic, specialty services, and genetic counseling; its research portfolio spans NIH-funded cooperative agreements (ADRC, ARTFL, LEFFTDS, ALLFTD, MarkVCID), foundation-supported programs (Hillblom Brain Aging Center, Bluefield Project, Tau Consortium), an active clinical trials program, a neurodegenerative disease brain bank, and iPSC-based disease modeling. Proprietary tools include TabCAT (tablet-based cognitive assessment), the original NIH EXAMINER battery, and a Dementia Care Pathway decision-support platform built with Quest Diagnostics.

The center serves patients with memory and cognitive disorders (including Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, and rapidly progressive dementias), their caregivers and families, research volunteers, and healthcare professionals, with community partnerships extending neurological care to underserved San Francisco populations. Revenue is generated through three primary streams: clinical care billed through UCSF Health (insurance-based), federal and foundation research grants (led by the National Institute on Aging and multiple private foundations), and philanthropic gifts (including a major 2025 Fein family naming gift). Distribution is primarily in-person at the Mission Bay campus with telemedicine extending reach to rural areas, and international impact is channeled through the co-directed Global Brain Health Institute with Trinity College Dublin. As a 501(c)(3) university research unit, the center carries no venture or private equity ownership.

Name

UCSF Memory and Aging Center

Legal name

The Regents of the University of California

Website

https://memory.ucsf.edu

Company type

Public

Founded year

1998

Operating status

Operating

Headcount range

101–250 employees

Short description

The UCSF Memory and Aging Center is a clinical research center within UCSF that diagnoses and treats neurodegenerative diseases, runs NIH- and foundation-funded dementia research and clinical trials, and trains clinicians, while serving patients, caregivers, and research participants.

Ownership category

akta.pro rank

Product category

Dementia Care Services

NAICS

Nursing and Residential Care Facilities (623)

SIC

Services-Nursing & Personal Care Facilities (8050)

akta.pro primary industry

Memory Care Care Management & Navigation (Dementia Care Coordination) (HLADACAJ)

Keywords

• Neurodegenerative disease research
• Dementia clinical care
• Alzheimer's research
• Cognitive assessment tools
• Neurology clinical trials

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Clinical Care Services: Patient care revenue through clinical services including Memory & Aging Center Clinic, Specialty Services, and Genetic Counseling. Insurance and patient fees cover only a portion of the cost of personalized treatment.
2. Research Grants and Funding: NIH-funded research programs including Alzheimer's Disease Research Center (ADRC), ARTFL, LEFFTDS, MarkVCID, and other research grants. National Institute on Aging is a primary sponsor.
3. Philanthropic Donations: Gifts and pledges from individuals supporting research and clinical care. The center is part of UCSF, a 501(c)(3) nonprofit organization. Donations support frontotemporal dementia research, Creutzfeldt-Jakob disease research, and art and science programs.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels6 records

Core offering

The UCSF Memory and Aging Center (now the Edward and Pearl Fein Memory and Aging Center) provides multidisciplinary clinical care, translational research, and professional training for patients with neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia, and related disorders. Core offerings include diagnostic evaluation at the Memory & Aging Center Clinic, genetic counseling, clinical trials, the NIH-funded Alzheimer's Disease Research Center, the Hillblom Brain Aging Center, the Neurodegenerative Disease Brain Bank, and proprietary cognitive assessment tools such as TabCAT.

Product overview

The UCSF Memory and Aging Center (now formally the Edward and Pearl Fein Memory and Aging Center) is a clinical research center offering a unified portfolio of dementia care, research, and education services. Its core clinical services include diagnostic evaluation and treatment for memory and cognitive disorders, supported by specialty programs such as genetic counseling, brain health care, and tablet-based cognitive assessment (TabCAT). Research infrastructure includes the Hillblom Brain Aging Center focused on digital tools and biomarkers, an active clinical trials program testing therapies for Alzheimer's disease, FTD, PSP, and other dementias, and collaborations with national Alzheimer's Disease Research Centers. Therapeutic and community programs encompass Art at the MAC including Gallery190 exhibitions, Creative Minds art projects, Artist in Residence, and the Arborvitae literary journal. Professional training programs including fellowships in behavioral neurology, neuropsychology, and the Global Brain Health Institute round out the educational offerings. Together these services provide comprehensive, multidisciplinary care while advancing scientific understanding of neurodegenerative diseases.

Differentiator

Problem solved

Functional benefit

Brands

• Global Brain Health Institute (GBHI): Partnership co-directed by UCSF and Trinity College Dublin that aims to reduce the scale and impact of dementia through training, prevention strategies, and knowledge sharing.
• Alzheimer's Disease Research Center (ADRC)
• Hillblom Brain Aging Center (HBAC)
• Gallery190
• Arborvitae

Products and services

• Memory & Aging Center Clinic In-person clinical services for diagnosis, treatment, and ongoing care for patients with neurodegenerative diseases, located at 1500 Owens Street, Suite 320, San Francisco.
• Specialty Services Specialized clinical programs for specific neurodegenerative conditions, complementing the core Memory & Aging Center Clinic.
• Genetic Counseling Services Genetic counseling for families affected by hereditary forms of dementia including familial Alzheimer's disease, familial FTD, and familial prion disease.
• Brain Health Care Services Comprehensive brain health care services including diagnostic evaluation, treatment planning, and ongoing care for patients with memory and cognitive disorders.
• Clinical Trials Program Active clinical trials evaluating treatments for Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, and other neurodegenerative conditions.
• Hillblom Brain Aging Center A research center funded by the Larry L. Hillblom Foundation focused on creating scientific resources to predict, prevent, and treat age-related brain disease, supporting digital assessment tools and biomarkers research.
• TabCAT Tablet-based Cognitive Assessment Tool Tablet-based cognitive testing platform used for standardized memory and cognitive assessment in clinical and research settings, developed and validated by UCSF researchers.
• Neurodegenerative Disease Brain Bank Brain donation program allowing research participants to consent to brain autopsy for research purposes to advance understanding of neurodegenerative diseases.
• Art at the MAC Art therapy and creative programs including Gallery190 exhibition space, Creative Minds community art projects, Artist in Residence program, and Arborvitae arts and literary journal.
• Professional Training Programs Training programs for future leaders in neurology, neuroscience, and brain health including Behavioral Neurology Training Program, Neuropsychology Training Program, and Global Brain Health Institute fellowships.

Quantifiable outcome

• Over 10,000 patients cared for through clinical and research programs since 1998
• +2 more outcomes

Named customers3 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Ten partnerships are on record, tiered supporting and core.

• Quest DiagnosticssupportingTechnology or IntegrationPartnership to develop the Dementia Care Pathway, an electronic decision-support platform for dementia care
• San Francisco Conservatory of MusicsupportingStrategic or Co-development PartnerPartnership highlighting links between arts and neuroscience, including Music, Creativity and Brain Science programs and Sleep & Dreams events
• Skidmore, Owings & Merrill LLPsupportingImplementation/ SI/ Consulting PartnerArchitecture firm consulted to help design the new office and clinical research space at UCSF Mission Bay campus in 2011
• Trinity College DublincoreStrategic or Co-development PartnerCo-director of Global Brain Health Institute alongside UCSF, aiming to reduce the scale and impact of dementia worldwide
• California Alzheimer’s Disease CentercoreStrategic or Co-development PartnerState of California-funded network of ten dementia care Centers of Excellence at California medical schools. UCSF is a designated center since 1984.
• Chinatown Public Health CentersupportingChannel Partner/ Reseller/ DistributorClinical partnership extending neurological clinical services to vulnerable populations in San Francisco
• Zuckerberg San Francisco General Hospital and Trauma CentersupportingChannel Partner/ Reseller/ DistributorClinical partnership through Neuro-Geriatrics program extending services to diverse populations
• Mission Neighborhood Health CentersupportingChannel Partner/ Reseller/ DistributorCommunity partnership extending brain health services to underserved neighborhoods
• Southeast Health CentersupportingChannel Partner/ Reseller/ DistributorCommunity partnership for brain health outreach and services
• Medical Respite and Sobering CentersupportingChannel Partner/ Reseller/ DistributorPartnership providing services to vulnerable populations including those experiencing homelessness

Scale indicators6 records

Recent moves9 records

Expansion highlights6 records

Market position

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/UCSFmac
• YouTubeyoutube.com/c/UCSFMemoryandAgingCenter
• Facebookfacebook.com/ucsfmemoryandaging
• LinkedInlinkedin.com/company/ucsf-memory-and-aging-center

Revenue estimate

Valuation estimate

Number of profiles

Profiles14 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about UCSF Memory and Aging Center