BioGrowing Probiotics Co.

What BioGrowing Probiotics Co. does

BioGrowing Probiotics Co., Ltd is a Shanghai-based probiotics ingredient and contract development manufacturer established in 2006 and operating as a holding subsidiary of JuneYao Health (605388.SH), part of the JuneYao Group. The company develops, produces, and distributes proprietary probiotic strains, finished probiotic supplements, and industrial starter cultures (BioGuard®) to B2B customers globally, exporting to 80+ countries including 22 of 27 EU member states. Headcount is reported at 51-100, and the company is led by a PhD-heavy R&D team (80%+ doctoral/master's degrees) under founder Song Jin'an.

The technical platform is built around a proprietary strain library of 50,000+ isolates with independent IP rights, sourced from Chinese regions such as Xinjiang, Tibet, and Inner Mongolia, plus protected manufacturing technologies including high-density fermentation (billions of CFU/gram of liquid), patented gastric-acid-resistant encapsulation, non-dairy-based freeze-drying protection (allergen elimination), liquid-nitrogen deep freezing granulation, and OralBubble™ micro-foam lozenge delivery (patented across China, US, EU, Japan, Australia). Clinical validation is anchored in 100+ peer-reviewed publications and RCTs in high-impact journals including Cell Metabolism (AKK WST01 live Akkermansia) and Food Research International (Lp-G18). A 36,666 sq meter production base in Qingpu District with 1,200 tons/year freeze-dried powder capacity — among the largest in Asia — supplies both ingredient and finished-product volumes.

Commercially, BioGrowing operates four revenue streams: (1) bulk probiotic raw material/ingredient sales (Flora-Focus® strains) to functional food and nutraceutical manufacturers; (2) ODM/CDMO custom formulation and manufacturing across 10+ delivery formats (capsules, sachets, tablets, powders, gummies, effervescent, popping candy, microbubble lozenges); (3) BioGuard® industrial starter culture sales (DVS cultures) for dairy and plant-based fermentation; and (4) licensing royalties on proprietary strains and patents. Go-to-market is enterprise field sales supplemented by active participation in 15+ global trade shows annually, with digital presence in CN/EN/ES/RU and strategic geographic expansion into Russia, Mexico, Australia, New Zealand, Southeast Asia, and Korea. Customer concentration is diversified across functional food, dietary supplement, pharmaceutical, and dairy verticals, with one named Global Top 500 dairy customer. International certifications (NSF cGMP, FDA, BRC GS, FSSC22000, ISO22000, Halal, Kosher, Canada NNHPD-FSRN, and US Self-Determined GRAS for BL-G101 and BC-G44) plus drafting participation in MIIT and QB/T industry standards create regulatory barriers to entry.

Name

BioGrowing Probiotics Co.

Legal name

BioGrowing Co.,Ltd

Website

https://biogrowing.com

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

51–100 employees

Short description

BioGrowing Probiotics Co. is a Shanghai-based B2B supplier of proprietary probiotic strains, ODM/CDMO finished products, and BioGuard® starter cultures, exporting to 80+ countries and serving functional food, nutraceutical, pharmaceutical, and dairy manufacturers with a 50,000+ strain library.

Ownership category

akta.pro rank

Product category

Probiotic Ingredients and Contract Manufacturing

NAICS

Dairy Product Manufacturing (3115)

SIC

Dairy Products (2020)

akta.pro primary industry

Probiotics (Strains, Spore-Formers, Synbiotic Components) (AFAJAKAE)

akta.pro secondary industries

Cultures, Probiotics & Fermentation Ingredients (Starter Cultures, Yeast, Adjuncts) (CRADAOAI), Plant-Based & Alternative Dairy Cultures (Vegan Yogurt/Cheese, Fermented Plant Beverages) (AFAJAJAG), Beverage Fermentation Cultures (Beer, Wine, Cider, Kombucha, Fermented Soft Drinks) (AFAJAJAC)

Keywords

• Probiotic ingredients
• Starter cultures
• Contract manufacturing
• Probiotic supplements
• Microbiome solutions

Headquarters

HQ city

Shanghai

HQ country

China

HQ region

Asia

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Probiotic Raw Material / Ingredient Sales: Sale of proprietary probiotic strains (bulk powders, freeze-dried bacterial powders) to B2B customers including functional food manufacturers, supplement brands, pharmaceutical companies, and dairy producers. Revenue is generated through per-kilogram pricing of finished strain ingredients with varying CFU counts.
2. ODM/CDMO Custom Formulation & Manufacturing: End-to-end custom development and manufacturing services for finished probiotic products (capsules, tablets, sachets, gummies, powders, effervescent tablets, popping candy, microbubble lozenges). Includes product design, strain selection, formulation, and packaging. Revenue generated through per-unit manufacturing fees and project-based development charges.
3. Starter Culture Sales (BioGuard®): Sale of industrial starter cultures (DVS - Direct Vat Set) for dairy and plant-based fermentation to commercial food and beverage manufacturers. Includes thermophilic, mesophilic, probiotic, and plant-based starter culture product lines.
4. Licensing Royalties (Strain IP): Licensing of proprietary strains and patented technologies to partners for use in their own product formulations, generating royalty income on approved applications and geographic markets.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

BioGrowing develops, manufactures, and globally distributes probiotic raw materials, proprietary star strains, and industrial BioGuard® starter cultures for dairy and plant-based fermentation. The company also delivers end-to-end ODM/CDMO custom formulation and contract manufacturing of finished probiotic products (capsules, sachets, tablets, gummies, powders, effervescents, popping candy, microbubble lozenges) to functional food, nutraceutical, pharmaceutical, and dairy manufacturers across 80+ countries.

Product overview

BioGrowing Probiotics Co. is a comprehensive probiotic solution provider offering a portfolio of branded products and contract manufacturing services. The core offering includes the Flora-Focus® star strains line (9-10 health functional directions), BioGuard® industrial starter cultures, and innovative consumer products like OralBubble™ microbubble lozenges, OralFlash™ flash-melt probiotics, and OralPOP® popping candy. The company provides end-to-end ODM/CDMO manufacturing services with diverse formats (capsules, sachets, tablets, powders) and operates a proprietary strain library of 50,000+ strains. Key strains include Akkermansia muciniphila AKKBG-001® and AKK WST01, Lactiplantibacillus plantarum J26 and Lp-G18, Weizmannia coagulans BC-G44, and specific strains for oral health (LPc-G110) and female care (Lc-G22).

Differentiator

Problem solved

Functional benefit

Brands

• Flora-Focus®: Star probiotic strains and functional health solutions covering areas including gut health, immunity, oral care, women's health, weight management, blood sugar management, skin health, and more.
• BioGuard®
• OralBubble™
• OralFlash™
• AKKBG-001®

Products and services

• Flora-Focus® Star Strains A flagship brand/portfolio of clinically validated, branded probiotic strains (e.g., AKKBG-001®, AKK WST01, J26, Lp-G18, LPc-G110, Lc-G22, BC-G44) covering gut health, immunity, oral care, female care, weight management, blood sugar management, skin health, and anti-H. pylori, sold as branded raw materials and as part of custom formulations for B2B customers worldwide.
• BioGuard® Starter Cultures Industrial-grade Direct Vat Set (DVS) cryogenic starter cultures for dairy and plant-based fermentation, evaluated across six dimensions (fermentation activity, post-acidity stability, texture, aroma, water retention, anti-phage). Includes thermophilic, mesophilic, probiotic, and plant-based starter culture product lines. Supplied to commercial dairy and plant-based food manufacturers globally.
• OralBubble™ Probiotic Microbubble Lozenge Innovative oral health probiotic lozenge with 10 billion CFU live bacteria, patented micro-foam technology with 5 global patents, targeting 8 major oral health issues including bad breath, gingivitis, and dental plaque. Sugar-free. Available as a finished consumer-format product and for B2B distribution.
• OralFlash™ Flash-Melt Probiotics Revolutionary 'melts-on-tongue' probiotic delivery format providing a refreshing sensation across 9 health function solutions, designed for convenience in travel and daily use, with the OralFlash™ trademark.
• OralPOP® Popping Candy Probiotics Functional probiotic popping candy with 10 billion CFU and a sugar-free formula targeting 8 oral health concerns, positioned for the children's functional food segment.
• Akkermansia muciniphila AKKBG-001® Proprietary heat-killed (postbiotic) Akkermansia muciniphila strain sourced from the intestinal tract of a healthy adult in Kashgar, Xinjiang. Supports weight management, metabolic health, and gut barrier integrity. Allergen-free production using protein-free culture medium; ≥2.0×10¹² TFU/g. Sold as a B2B probiotic ingredient under the AKKBG-001® trademark.
• Akkermansia muciniphila AKK WST01 China's first RCT-validated live Akkermansia muciniphila strain. Clinical study published in Cell Metabolism demonstrated improvements in BMI, body weight, and fat mass in overweight/obese T2D patients. Covered by 13-country patents and self-GRAS certified. Sold as a B2B probiotic ingredient.
• Lactiplantibacillus plantarum J26 Weight management and metabolic health strain sourced from traditional fermented dairy in Inner Mongolia's Horqin grassland. Supported by 8 national invention patents and 30+ peer-reviewed papers. Available in both live and postbiotic forms for capsules, beverages, yogurt, and bakery applications. Sold as a B2B probiotic ingredient.
• Lactiplantibacillus plantarum Lp-G18 Flora-Focus® star strain sourced from natural fermented sour cow milk from Ili, Xinjiang. Research published in Food Research International (IF=8) demonstrating gut-liver axis benefits. Supports liver protection, anti-inflammation, enhanced metabolism, lipid reduction, immune modulation, anti-H. pylori, and anti-aging claims. Sold as a B2B probiotic ingredient.
• Lacticaseibacillus paracasei LPc-G110 Oral health probiotic strain clinically proven to reduce oral malodor and inhibit periodontal pathogens. Adaptable across various oral care probiotic formats including lozenges, tablets, and toothpastes. Part of the Flora-Focus® oral health solutions line.
• Lactobacillus crispatus Lc-G22 Female care probiotic strain that colonizes and proliferates in the vaginal environment, effectively inhibiting Candida and other pathogens. Clinically proven for prevention and treatment of vulvovaginal candidiasis (VVC) and supporting vaginal microbiome balance. Sold as a B2B probiotic ingredient.
• Weizmannia coagulans BC-G44 High-stability, heat-resistant probiotic spore strain sourced from fermented yellow peach. GRAS certified. Maintains ≥95% viability after 2 years at room temperature, ≥85% after 5 minutes at 140°C, ≥85% after 60 minutes in pH 2.0 gastric acid, and ≥55% after 6 hours in bile salts. Sold as a B2B probiotic ingredient, particularly suitable for hot beverage and food applications.
• Probiotic Coffee Solid Beverage Functional coffee beverage combining Weizmannia coagulans BC-G44 with premium Arabica coffee, cold-brew freeze-dried with blood orange and sweet orange notes. Delivers 10 billion CFU live probiotics in a 2g portable stick-pack; maintains 86.85% viability after 5 minutes at 140°C dry heat.
• BioGrowing™ Probiotic Chewable Tablets for Liver Health Innovative chewable liver-care tablet combining patented probiotic strains (incl. Lactiplantibacillus plantarum Lp-G18) with food-as-medicine ingredients and four natural botanical extracts. Each tablet contains 10 billion CFU live probiotics; designed for business dinners and travel use.
• ODM/CDMO Custom Formulation & Manufacturing Services End-to-end original design manufacturing and contract development services for finished probiotic products in multiple formats (capsules, sachets, tablets, powders, gummies, effervescent tablets, popping candy, microbubble lozenges). Includes product design, strain selection, formulation, manufacturing, and packaging, with 1000+ mature formulas available. Targeted at functional food, nutraceutical, pharmaceutical, and dairy manufacturers.

Quantifiable outcome

• Akkermansia muciniphila AKKBG-001®: 88% of participants showed effective weight reduction in a 30-day trial (88% effective rate in weight management sample efficacy report)
• +5 more outcomes

Named customers4 records

Segments6 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

Ten partnerships are on record, tiered core and minor.

• Chinese Academy of SciencescoreStrategic or Co-development PartnerR&D and academic partnership for probiotic strain research, functional component analysis, and biotechnology innovation. The company collaborates with Chinese Academy of Sciences on cutting-edge probiotic research and technology development.
• Northeast Agricultural UniversitycoreStrategic or Co-development PartnerIndustry-academia-research base and postdoctoral mobile station partnership. Joint talent development and graduate training. Collaborative research on probiotic strains and fermentation technology.
• Jiangnan UniversitycoreStrategic or Co-development PartnerAcademic partnership for probiotic research, food science, and biotechnology development. Contributes to BioGrowing's R&D capabilities and innovation pipeline.
• Zhejiang UniversitycoreStrategic or Co-development PartnerUniversity partnership for joint research in probiotic science, fermentation technology, and food applications.
• China Agricultural UniversityminorStrategic or Co-development PartnerAcademic partnership for probiotic research and agricultural biotechnology applications.
• International Probiotics Association (IPA)coreStrategic or Co-development PartnerBioGrowing is an active member of the International Probiotics Association, participating in IPA World Congress and Probiota conferences. Supports industry standards, scientific exchange, and global probiotic market development.
• Beijing Agricultural CollegeminorStrategic or Co-development PartnerJoint training and practice base for graduate students. Collaborative talent development in probiotic science and biotechnology.
• China Dairy Industry AssociationminorOthersIndustry association membership supporting dairy probiotic applications and standards development.
• China Food Additives and Ingredients AssociationminorOthersIndustry association membership contributing to food additive standards and probiotic ingredient applications.
• Shanghai Biopharmaceutical Industry AssociationminorOthersIndustry association membership in Shanghai's biopharmaceutical sector supporting regulatory and market development.

Scale indicators12 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Lallemand: Privately held Canadian company specializing in yeast, bacteria, and probiotic ingredients for food, beverage, and supplement industries. Closely comparable to BioGrowing in B2B probiotics, dairy cultures, and ODM/CDMO services, with a similar global export footprint and privately held ownership structure.
• Sabinsa: US-based manufacturer of patented herbal extracts, nutraceuticals, and probiotic ingredients. Comparable to BioGrowing in B2B ingredient supply, scientific substantiation, and patent-protected product offerings for the dietary supplement industry, with similar global export reach.
• Novonesis (Chr. Hansen): Global market leader in probiotic cultures and enzymes, formed from the 2024 merger of Chr. Hansen and Novozymes. Directly comparable B2B probiotic ingredient business with an extensive strain library, dairy cultures, and global customer base across food, beverage, dietary supplements, and animal health—competing head-to-head with BioGrowing for enterprise accounts.
• Lesaffre: French family-owned global yeast and fermentation company with a dedicated Gnosis by Lesaffre probiotics and health ingredients division. Closely comparable to BioGrowing in B2B probiotic ingredients, starter cultures, and ODM/CDMO services for dietary supplements and functional foods, with similar privately-held profile.

Regional players

• Morinaga Milk Industry: Japanese dairy and functional ingredient company with a strong BIFIDUS and probiotic ingredient business. Comparable to BioGrowing in probiotic R&D, clinical validation, and Asia-Pacific market presence, though primarily serving Japanese and broader Asian markets rather than competing directly in Western markets.

Broad incumbents

• ADM (Archer Daniels Midland): Global nutrition and agricultural processor with significant probiotics and health ingredients business serving dietary supplement, food, and beverage customers. Competes with BioGrowing at the largest multinational customer accounts across its Human Nutrition and Health & Wellness segments.
• International Flavors & Fragrances (IFF) Health & Biosciences: Acquired DuPont Nutrition & Biosciences in 2021, creating one of the largest probiotic and cultures portfolios globally. Competes with BioGrowing in B2B probiotic ingredients for dietary supplements, functional food, and dairy applications, with a broader specialty food ingredients and flavor portfolio.
• Kerry Group: Global taste and nutrition company with a significant probiotics business including Ganeden (acquired 2017). Competes with BioGrowing in B2B probiotic ingredients and functional food applications, with a broader portfolio spanning food ingredients, taste solutions, and consumer health.

Emerging players

• Ganeden (Kerry): US-based probiotic ingredient company acquired by Kerry Group in 2017, known for GanedenBC30 (Bacillus coagulans) strain. Comparable to BioGrowing in B2B probiotic ingredient sales for functional food, beverage, and dietary supplement applications, with significant presence in the US market.
• Probi AB: Swedish publicly-listed probiotic company focused on proprietary probiotic strains and ODM/CDMO services. Directly comparable business model to BioGrowing with a strong clinical research focus, though smaller scale and primarily focused on Europe and North America.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/Biogrowing.Probiotics
• LinkedInlinkedin.com/company/biogrowing-co-ltd

Compliance12 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BioGrowing Probiotics Co.