What Amplitude Surgical does

Amplitude Surgical is a French medical device company founded in 1997 in Valence, specializing in surgical technologies for lower-limb orthopaedics, primarily hip and knee replacement procedures. The company's product portfolio spans acetabular cups and femoral stems for total hip arthroplasty (SATURNE II, EVOK, INTEGRALE, ACOR), total and unicompartmental knee prostheses (SCORE II, ANATOMIC, TRAX CR, UNI SCORE), the Andy orthopaedic surgical robot (CE mark approved November 2025), the AMPLIVISION computer-assisted surgery navigation platform, the i.M.A.G.E. patient-specific instrumentation system, sports medicine devices (COMETE), and AMPLIFIX bone cements. Manufacturing occurs at facilities in Valence and Etoile in the Rhône Valley, with clinical validation through surgeon collaboration.

The company sells to orthopaedic surgeons, hospitals, and surgical centers across 33 countries through a direct sales force and exclusive distributor network. Direct business represents approximately 93% of total sales. France is the home market, accounting for 73% of revenue, while international operations are managed through wholly-owned subsidiaries in Australia, Benelux, Brazil, Germany, South Africa, and Switzerland. R&D investment stands at 4.6% of turnover, with 58 R&D engineers among 429 total employees. R&D output is clinically validated, notably the SCORE II femoral component designed from a digitized study of 1,200 knees using AMPLIVISION navigation.

On October 9, 2025, Zydus MedTech (France) SAS, a subsidiary of Indian pharmaceutical group Zydus Lifesciences Limited, completed a simplified tender offer taking Amplitude Surgical private. FY 2024-25 consolidated revenue was €110.8 million, up 5.7% at constant exchange rates, with EBITDA margin of approximately 27%. Revenue is generated primarily through one-time hardware sales of implants and associated instruments, with contract-based B2B medical device pricing. The company has continued expanding its commercial footprint, acquiring France-based FBC Medical in April 2026 to internalize sales capabilities, and entered robotic-assisted surgery commercialization following the Andy robot's first European clinical use in February 2026.

Name

Amplitude Surgical

Legal name

AMPLITUDE SAS

Website

https://amplitude-ortho.com

Company type

Private

Founded year

1997

Operating status

Operating

Headcount range

251–500 employees

Short description

Amplitude Surgical is a French medical device company, founded in 1997 and now under Zydus Lifesciences ownership, that designs and manufactures hip and knee orthopaedic implants, the Andy surgical robot, and AMPLIVISION computer-assisted surgery systems, selling to hospitals and surgeons in 33 countries.

Ownership category

akta.pro rank

Product category

Orthopaedic Medical Devices

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Orthopedic Joint Reconstruction Implants (Hip/Knee/Shoulder/Elbow/Ankle) (HLAHAEAA)

akta.pro secondary industries

Surgical Navigation, Robotics & Patient-Matched Instrumentation (Ortho/Spine) (HLAHAEAL), Hip & Knee Reconstruction (Arthroplasty) (HLAKALAH), 3D-Printed & Patient-Specific Implants (Custom Ortho/Spine/Cranial) (HLAHAEAJ)

Keywords

• Orthopaedic implants
• Lower limb surgery
• Hip replacement devices
• Knee prosthesis
• Surgical robotics

Headquarters

HQ city

Valence

HQ country

France

HQ region

Europe

Offices8 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Orthopaedic Implants and Surgical Products: Sale of orthopaedic implants (hip and knee prostheses), surgical instruments, computer-assisted surgery systems, and the Andy surgical robot. Revenue model is primarily one-time hardware sales with associated instruments and consumables. FY 2024-25 revenue of €110.8 million, up 5.7% at constant exchange rates.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels4 records

Core offering

Amplitude Surgical designs, manufactures, and distributes orthopaedic implants and surgical technology for lower-limb procedures (hip and knee). Its portfolio includes acetabular cups, femoral stems, total and unicompartmental knee prostheses, bone cements, ligament repair devices, the AMPLIVISION computer-assisted surgery navigation system, the i.M.A.G.E. patient-specific instrumentation system, and the Andy orthopaedic surgical robot for precision bone resection.

Product overview

Amplitude Surgical is a French medical device company specializing in surgical technologies for lower-limb orthopaedics. Founded in 1997 in Valence, France, the company operates as a unified product portfolio covering hip and knee implants, surgical robots, and computer-assisted surgery systems. The product ecosystem includes: acetabular cups and femoral stems (SATURNE II, EVOK, INTEGRALE, ACOR) for hip replacement; total and unicompartmental knee prostheses (SCORE II, ANATOMIC, TRAX CR) for knee replacement; the Andy robotic surgical system for precision bone resection; the AMPLIVISION computer-assisted surgery navigation platform and i.M.A.G.E. patient-specific instrumentation system; sports medicine products (COMETE, ACLip) for ligament repair; and AMPLIFIX bone cements. Products are designed in Valence with clinical validation, manufactured at production sites in Valence and Etoile in the Rhône Valley, and distributed through direct sales representatives and exclusive distributors across 33+ countries.

Differentiator

Problem solved

Functional benefit

Brands

• Andy: Orthopaedic surgical robot designed for precision in bone resections
• AMPLIVISION
• i.M.A.G.E.
• AMPLIFIX
• COMETE
• E.T.O.I.L.E.
• SATURNE
• SCORE
• EVOK
• ACOR
• TRAX
• STELLAR
• HORIZON

Products and services

• SATURNE II Cementless cylindrico-spherical dual mobility acetabular cup used in total hip arthroplasty. The liner moves within the metal cup and the femoral head moves within the liner, increasing joint stability and reducing wear. CE2797 certified.
• SCORE II Primary total knee arthroplasty implant with rotating platform mobile bearing and PCL-sacrificing design. Femoral component design based on study of 1,200 knees digitized using the AMPLIVISION navigation system.
• TRAX CR Primary total knee prosthesis with fixed bearing and cruciate-retaining design. Features anatomical lateralized trochlear groove, single radius design, and AXPe vitamin E enriched polyethylene articulating surfaces.
• Andy Orthopaedic surgical robot designed for precision in bone resections during lower-limb surgery. Aims to improve surgical outcomes and recovery times for orthopaedic procedures.
• AMPLIVISION Computer Assisted Surgery (CAS) navigation system providing navigation-assisted surgery capabilities for improved implant placement accuracy in hip and knee procedures. CE marked.
• i.M.A.G.E. Patient-specific instrumentation system for knee replacement surgery, used with or without AMPLIVISION navigation for personalized surgical approaches.
• EVOK Range of cementless femoral stems available in Standard, Lateralized, and High Offset options. Features quadrangular cross-section with press-fit coating and proximal/distal grooves for higher bone contact.
• STELLAR Cementless acetabular cup with dimensional press-fit. Compatible with BIOLOX Delta ceramic liner or polyethylene liner. Features up to 4 holes for additional cortical fixation screws.
• ACOR monobloc Primary anatomical femoral stem available in cemented and cementless versions in Standard and Lateralized models. Features an anatomic 8° metaphyseal curvature matching the proximal femur's natural curvature.
• INTEGRALE Primary straight femoral stem with full hydroxyapatite (HAP) coating, ovoid metaphyseal cross-section for primary stability, and 137° neck-shaft angle.
• ANATOMIC Primary total knee arthroplasty implant matching bone morphology, posterior stabilized, fixed bearing, PCL-sacrificing design. Features trochlear groove angled 6° with constant radius of curvature.
• SCORE Primary total knee arthroplasty implant with stability through congruency and rotating platform mobile bearing design. Can be used with or without AMPLIVISION navigation.
• UNI SCORE Unicompartmental knee prosthesis used to replace part of the joint surface of the femur and tibia in partial knee replacement procedures.
• AMPLIFIX Bone cement product line for implant fixation. Includes AMPLIFIX 1 (standard viscosity) and AMPLIFIX 3 with Gentamicin (low viscosity with antibiotic).
• COMETE Control Adjustable cortical fixation device for ligament repair with pull-out strength of 1844 N. Features loop length adjustment and locking mechanism for graft fixation.
• CliniRecord Clinical follow-up platform for patient outcome tracking and post-surgical monitoring.

Quantifiable outcome

• Approximately 27% EBITDA margin for FY 2024-25
• +2 more outcomes

Named customers2 records

Segments2 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Two partnerships are on record, tiered minor and core.

• FBC MedicalminorStrategic or Co-development Partner · 30 April 2026Amplitude Surgical acquired 100% share capital of France-based FBC Medical for €700,000. FBC Medical had operated as a sales agent under exclusive agreement with Amplitude Surgical across multiple French departments. Acquisition internalizes commercial capabilities previously outsourced to third-party sales agents.
• eCential RoboticscoreStrategic or Co-development Partner · 27 April 2022Long-term partnership between French MedTech companies eCential Robotics and Amplitude Surgical to enhance knee surgery robotics. Companies joined forces to combine expertise in surgical robotics and orthopaedic implants.

Scale indicators9 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Mathys (Mathys European Orthopaedics): European-focused orthopaedic implant company with hip and knee product lines, similar in scale and geographic focus to Amplitude and acquired by various PE-backed owners historically.
• Corin: UK-headquartered orthopaedic implant specialist with hip and knee portfolios and an emphasis on personalised, surgeon-collaborative product design, mirroring Amplitude's go-to-market and innovation philosophy.
• Exactech: US-based orthopaedic implant and instrumentation specialist focused on hip and knee arthroplasty, comparable in product portfolio breadth though larger in US distribution.
• Medacta International: Swiss orthopaedic specialist with comparable focus on hip and knee implants, patient-matched instrumentation (MyKnee), and the NextAR minimally invasive surgical navigation platform — closely aligned business model and European footprint.

Broad incumbents

• Johnson & Johnson MedTech (DePuy Synthes): Diversified MedTech giant whose DePuy Synthes orthopaedics division competes in hip/knee reconstruction and with the VELYS robotic-assisted surgery platform.
• Stryker: Global orthopaedic leader and Amplitude's most direct competitor in robotics through the Mako SmartRobotics platform for hip and knee arthroplasty, which dwarfs Andy's installed base and clinical evidence.
• Smith+Nephew: Orthopaedic and sports-medicine major that competes with Amplitude in hip/knee implants and with the CORI and ROSA robotics platforms, with a much larger international commercial footprint.
• Zimmer Biomet: One of the largest pure-play orthopaedic device companies, competing head-to-head with Amplitude across hip and knee implants and the ROSA Knee robotics system.
• B. Braun / Aesculap: German MedTech group offering orthopaedic hip and knee implants and surgical instruments in Europe; a long-standing competitor in French and German hospitals where Amplitude also has direct subsidiaries.

Emerging players

• Conformis: Patient-specific knee implant maker whose iTotal/iUni custom instrumentation approach competes conceptually with Amplitude's i.M.A.G.E. patient-specific guides system.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/amplitudesurgical

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries7 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Amplitude Surgical