repha gmbh

What repha gmbh does

Repha GmbH Biologische Arzneimittel is a German family-owned pharmaceutical company founded in 1925 in Hannover by Friedrich Bradtmöller and now headquartered in Langenhagen. The company is in its fourth generation of family ownership under Björn Bradtmöller and specializes in evidence-based phytotherapy, developing and manufacturing herbal medicines, dietary supplements, and cosmetics. Its portfolio is organized around three core therapeutic areas — respiratory tract (ANGOCIN Anti-Infekt N, MARRUBIN), urinary tract (ANGOCIN, ANGOCIN Mannose Plus), and digestive tract (MYRRHINIL-INTEST, NORTASE, UNEXYM vital) — and has expanded into adjacent categories such as sleep (ALLUNA Schlaf) and dermo-cosmetics (REPHADERM, REPHASTASAN).

The company's product differentiation rests on proprietary multi-herb formulations, including nasturtium and horseradish (ANGOCIN), myrrh, coffee charcoal and chamomile (MYRRHINIL-INTEST), and a vegetarian fungal digestive-enzyme blend (NORTASE). Scientific validation is a central pillar: more than 80 studies and 60+ research projects over the past 15 years, partnerships with 12+ German universities (Charité Berlin, Universitätsklinikum Bonn, University of Ulm), and molecular mechanism validation via confocal laser endoscopy. Both ANGOCIN and MYRRHINIL-INTEST are listed in German S3 clinical guidelines, providing physician-level endorsement for clinical use.

Repha's business model is B2B sales-led and channel-exclusively through pharmacies in Germany — public, clinic, and mail-order — distributed via pharmaceutical wholesalers including NOWEDA, and supported by a DocCheck-authenticated Fachbereich portal and a Phytocademy scientific-marketing platform for healthcare professionals. Geographic expansion into Austria has been executed through a distribution partnership with Sanova Pharma GesmbH. Revenue mechanics follow a traditional branded OTC/phytopharmaceutical model: pharmacy-channel sales of multi-SKU branded products at typical consumer pharma price points, with no disclosed subscription, licensing, or platform revenue. The company is preparing for its 100-year anniversary in 2025 and continues to invest in R&D infrastructure, including a new laboratory and office building completed at the Langenhagen site in 2024.

Name

repha gmbh

Legal name

Repha GmbH Biologische Arzneimittel

Website

https://repha.de

Company type

Private

Founded year

1925

Operating status

Operating

Headcount range

1–10 employees

Short description

Repha GmbH is a 100-year-old, fourth-generation family-owned German pharmaceutical company specializing in evidence-based phytotherapy, producing herbal medicines, dietary supplements, and cosmetics distributed exclusively through pharmacies in Germany and Austria.

Ownership category

akta.pro rank

Product category

Herbal Pharmaceuticals (Phytotherapy)

NAICS

Pharmaceutical and Medicine Manufacturing (3254)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Herbal & Botanical Supplements (CRADAGAD)

akta.pro secondary industry

Probiotics & Digestive Health Supplements (CRADAGAF)

Keywords

• Herbal pharmaceuticals
• Phytotherapy medicines
• Botanical anti-infectives
• Vegetarian enzyme therapy
• Digestive health supplements

Headquarters

HQ city

Langenhagen

HQ country

Germany

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Phytopharmaceutical Medicines: Prescription and over-the-counter herbal medicines sold exclusively through pharmacies, including ANGOCIN Anti-Infekt N, MYRRHINIL-INTEST, NORTASE, ALLUNA Schlaf, MARRUBIN, and REPHALGIN N. Revenue from established products with 60+ years of market presence and ongoing scientific evidence base.
2. Dietary Supplements: Non-prescription products including BILISAN Leberkomplex, KROPHAN Jodkomplex, VENTRACID, UNEXYM vital, REPHALYSIN C, and ANGOCIN Mannose Plus sold through pharmacies.
3. Cosmetics: Cosmetic products including REPHADERM Balsam (protective skin balm) and REPHASTASAN Creme (vein and sports massage cream) sold through pharmacies.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Repha GmbH is a family-owned pharmaceutical manufacturer specializing in evidence-based phytotherapy. It develops, produces, and sells prescription and over-the-counter herbal medicines (e.g., ANGOCIN Anti-Infekt N, MYRRHINIL-INTEST, NORTASE, ALLUNA Schlaf, MARRUBIN), food supplements (e.g., REPHALYSIN C, BILISAN, KROPHAN, VENTRACID, UNEXYM vital), homeopathic remedies (REPHALGIN N), and cosmetics (REPHADERM Balsam, REPHASTASAN Creme). All products are manufactured in Germany and distributed exclusively through pharmacies.

Product overview

Repha GmbH is a family-owned pharmaceutical company specializing in evidence-based phytotherapy (plant-based medicines) and natural health solutions. The product portfolio consists of herbal medicines (Arzneimittel), food supplements (Nahrungsergänzungsmittel), and cosmetics (Kosmetika). Core herbal medicines include ANGOCIN® Anti-Infekt N (respiratory/urinary infections), MYRRHINIL-INTEST® (gastrointestinal disorders), NORTASE® (vegetarian digestive enzymes for pancreatic insufficiency), ALLUNA® Schlaf (sleep disorders), MARRUBIN® (cough/bronchial), and REPHALGIN® N (homeopathic headache treatment). Food supplements include REPHALYSIN® C (immune support), BILISAN® Leberkomplex (liver function), KROPHAN® Jodkomplex (thyroid iodine), VENTRACID® (digestive support), UNEXYM® vital (digestive harmony), and ANGOCIN® MANNOSE PLUS (urinary tract). Topical products include REPHA-OS® mouth spray, REPHADERM® skin balm, and REPHASTASAN® vein/massage cream. The company focuses on three therapeutic areas: respiratory tract, urinary tract, and digestive tract.

Differentiator

Problem solved

Functional benefit

Brands

• ANGOCIN® Anti-Infekt N: Herbal medicine for respiratory and urinary tract infections, containing watercress and horseradish.
• MYRRHINIL-INTEST®
• NORTASE®
• ALLUNA® Schlaf
• MARRUBIN®
• REPHALGIN® N
• REPHA-OS® Mundspray
• REPHADERM®
• REPHASTASAN®
• REPHALYSIN® C
• BILISAN® Leberkomplex
• KROPHAN® Jodkomplex
• VENTRACID®
• UNEXYM® vital
• ANGOCIN® MANNOSE PLUS

Products and services

• ANGOCIN Anti-Infekt N Herbal anti-infective medicine containing nasturtium (200mg) and horseradish (80mg) for the relief of acute inflammatory diseases of the bronchi, sinuses, and urinary tract. Sold exclusively through pharmacies in Germany and Austria.
• MYRRHINIL-INTEST Traditional herbal medicine combining myrrh (100mg), coffee charcoal (50mg), and chamomile extract (70mg) for the supportive treatment of gastrointestinal disorders with non-specific diarrhea, mild cramps, and flatulence. Sold exclusively through pharmacies.
• NORTASE Digestive enzyme replacement for maldigestion due to impaired pancreatic function, containing vegetarian fungal enzymes (Rizolipase, protease, amylase) derived biotechnologically from Japanese rice fungus (Rhizopus oryzae). Repha is the only global provider of medicines with these innovative fungal enzymes, offering a vegetarian alternative to porcine pancreatin. Sold exclusively through pharmacies.
• ALLUNA Schlaf Plant-based sleep aid for the treatment of sleep disorders containing valerian root extract (187.5mg) and hop cone extract (42mg). Sold exclusively through pharmacies.
• MARRUBIN Andorn-Bronchialtropfen Traditional herbal medicine (Andornkraut-Fluidextrakt) for mucus loosening in cough associated with colds. Contains the active ingredient marrubiin from horehound (Andorn). Sold exclusively through pharmacies.
• REPHALGIN N Homeopathic headache remedy using homeopathic triturations of jasmine, iris, Canadian bloodroot, and wormwood for gradual and sustained improvement of headaches. Sold exclusively through pharmacies.
• REPHA-OS Mundspray Oral spray containing herbal ingredients including myrrh, bloodroot, ratanhia, peppermint, eucalyptus, clove, and anise for mouth and throat health. Sold exclusively through pharmacies.
• ANGOCIN Mannose Plus Food supplement combining angelica extract with D-mannose for urinary tract support. Sold exclusively through pharmacies.
• REPHALYSIN C Food supplement with fermentation concentrate from probiotic bacteria (Escherichia coli 'EC Gut'-DSM 16481) for maintaining natural immune function, containing 100 µg selenium. Sold exclusively through pharmacies.
• BILISAN Leberkomplex Food supplement combining milk thistle, turmeric, and choline for maintaining normal liver function. Sold exclusively through pharmacies.
• KROPHAN Jodkomplex Food supplement with natural iodine from bladderwrack seaweed and selenium from mustard seed extract for normal thyroid function. Sold exclusively through pharmacies.
• VENTRACID Food supplement with turmeric extract, choline, and plant-based enzyme concentrate supporting healthy digestion by promoting liver, bile, and intestinal functions. Sold exclusively through pharmacies.
• UNEXYM vital Food supplement combining vital substances and plant powders including gentian, horseradish, cinnamon, yarrow, dandelion, ginger, and caraway to harmonize the digestive tract. Sold exclusively through pharmacies.
• REPHADERM Balsam Protective and care-intensive cosmetic balm for irritated and heavily stressed skin, containing herbal extracts of sage, bitter wormwood, rosemary, echinacea, and myrrh. Sold exclusively through pharmacies.
• REPHASTASAN Creme Vein, sport, and massage cream combining plant extracts including arnica, comfrey, witch hazel, and horse chestnut. Sold exclusively through pharmacies.

Quantifiable outcome

• Over 1000% revenue growth since 1990, with workforce tripled over the same period
• +4 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

Feature3 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• Sanova Pharma GesmbHcoreChannel Partner/ Reseller/ Distributor · 1 January 2021Distribution partnership (Vertriebskooperation) for ANGOCIN Anti-Infekt N and ALLUNA Schlaf in Austria. MYRRHINIL-INTEST distribution was also established in Austria through Sanova in 2021.
• Charité BerlincoreStrategic or Co-development PartnerResearch partnership for molecular biology studies on MYRRHINIL-INTEST. Collaborated on Tight Junction research using confocal laser endoscopy, confirming the product's barrier-stabilizing effect directly in the human intestine at over 1000x magnification.
• Universitätsklinikum BonncoreStrategic or Co-development PartnerClinical study partnership showing ANGOCIN Anti-Infekt N can improve quality of life in catheter-dependent quadriplegic patients by reducing urinary tract infection frequency.
• Universitätskliniken Essen-MittecoreStrategic or Co-development PartnerUniversity hospital partnership for clinical studies on ANGOCIN Anti-Infekt N, MYRRHINIL-INTEST, and NORTASE.
• Universität UlmcoreStrategic or Co-development PartnerResearch cooperation with Universität Ulm established in 2016, representing the 12th partner university. Active in clinical and basic research.
• Universitäten Freiburg, Leipzig, Heidelberg, GießencoreStrategic or Co-development PartnerUniversity partnerships for clinical studies and basic research on the efficacy of ANGOCIN Anti-Infekt N, MYRRHINIL-INTEST, and NORTASE under the direction of professors.
• NOWEDA Apothekergenossenschaft eGminorChannel Partner/ Reseller/ DistributorPharmacy cooperative and wholesale partner for distributing Repha products to pharmacy members throughout Germany.

Scale indicators5 records

Recent moves8 records

Expansion highlights5 records

Direct peers

• Cesra Arzneimittel GmbH & Co. KG: Cesra is a German manufacturer of herbal medicinal products and natural cosmetics with a pharmacy-channel focus. Its phytopharmaceutical portfolio (e.g., Cefavora, Hepar SL) competes with Repha's herbal medicines in cardiovascular, liver, and immune indications, with the same scientific-marketing approach.
• Dr. Loges & Co. GmbH: Dr. Loges is a German manufacturer of plant-based and natural medicinal products distributed through pharmacies, with a focus on scientific evidence and healthcare professional marketing. It competes with Repha in phytotherapy categories including immune, digestive, and metabolic health with comparable product positioning.
• Klein Pharma GmbH: Klein Pharma is a German pharmaceutical company specializing in plant-based, homeopathic, and anthroposophic medicines sold through pharmacies. Its portfolio overlaps with Repha in traditional herbal formulations and pharmacy-exclusive distribution, making it a comparable mid-sized German phytopharma player.
• Engelhard Arzneimittel GmbH & Co. KG: Engelhard is a German family-owned pharmaceutical company focused on over-the-counter herbal and homeopathic medicines, sold primarily through pharmacies. Its product portfolio in respiratory and digestive indications (e.g., Prospan, isla-Moos) directly competes with Repha's ANGOCIN, MYRRHINIL-INTEST, and MARRUBIN in the same pharmacy channel.
• Bionorica SE: Bionorica SE is Germany's largest phytopharmaceutical company, specializing in evidence-based herbal medicines for respiratory, urinary, and gynecological indications. It is the most direct competitor to Repha, sharing the same scientific-marketing model targeting healthcare professionals, the same pharmacy-only distribution approach, and overlapping therapeutic areas (e.g., UTI, sinusitis).
• Salus Group (Salus Haus GmbH & Co. KG): Salus Haus is a German family-owned manufacturer of herbal medicinal products, dietary supplements, and tonics sold through pharmacies and health food stores. The company is a direct peer in herbal medicines, with overlapping digestive and immune products (e.g., Salus digestive tonics) and similar long-standing brand heritage.
• A. Vogel AG (Bioforce AG): A. Vogel/Bioforce is a Swiss manufacturer of plant-based medicines and natural health products, with strong pharmacy and health-store distribution in Germany. It is a direct peer in the herbal cold/respiratory and digestive categories, competing with Repha's ANGOCIN, MARRUBIN, and digestive supplements through similar healthcare-professional-led marketing.
• Heel GmbH (Biologische Heilmittel Heel): Heel is a German pharmaceutical company specializing in combination homeopathic and plant-based medicines distributed through pharmacies globally. While more homeopathy-focused, it overlaps with Repha in multi-herbal combination products, scientific marketing to healthcare professionals, and pharmacy-channel distribution in Germany and internationally.

Broad incumbents

• Bayer AG (Consumer Health): Bayer Consumer Health is a major global OTC and phytopharmaceutical player, having acquired Steigerwald Arzneimittel and integrating it into its consumer health business. It competes with Repha across multiple categories (digestive, respiratory, vitamins) with substantially larger marketing budgets and global distribution.
• Dr. Willmar Schwabe GmbH & Co. KG: Schwabe Group is the world's leading manufacturer of plant-based medicines (e.g., Tebonin, Umckaloabo), part of a broader pharma and consumer health portfolio. As a much larger, more internationally diversified competitor, it represents the broad incumbent benchmark in evidence-based phytotherapy that Repha's clinical-marketing model aspires to emulate.

Market position

Strengths6 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/repha-gmbh

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about repha gmbh