Lexi-Comp, Inc.

What Lexi-Comp, Inc. does

Lexi-Comp, Inc. (operating historically as Lexicomp and now rebranded as UpToDate Lexidrug) provides evidence-based drug referential content solutions to healthcare professionals globally. Founded in 1978 and headquartered in Hudson, United States, the company was acquired by Wolters Kluwer and now operates as a product line within Wolters Kluwer's Health division alongside UpToDate, Medi-Span, and Simplifi+ Pharmacy Compliance. The core product, UpToDate Lexidrug, delivers comprehensive drug information supporting patient-specific clinical decision-making by pharmacists, physicians, and other clinicians across the continuum of care. The technology is content-centric, built on a curated drug referential library that healthcare institutions access for medication decision support.

The product portfolio includes UpToDate Lexidrug (formerly Lexicomp) as the core drug referential solution, Medi-Span as a suite of embedded drug data solutions designed for integration into healthcare IT systems (including Price Rx for pricing information), and Simplifi+ Pharmacy Compliance as an add-on module for pharmacy regulatory compliance. The platform architecture emphasizes interoperability, with Medi-Span embedding directly into clinical workflows and UpToDate Lexidrug providing the referential layer. Distribution is global, served through Wolters Kluwer's enterprise sales organization with dedicated regional presence across the Americas, Europe, and Asia-Pacific.

Lexi-Comp generates revenue through subscription-based recurring licensing of its drug decision support solutions to healthcare institutions, including hospitals, pharmacy chains, and other healthcare enterprises. The go-to-market motion is enterprise field sales with quote-based pricing (no publicly disclosed price points), engaging customers via Wolters Kluwer's solutions directory and Contact Us CTAs. Customer segments are healthcare professionals — primarily pharmacists, physicians, and clinical leaders — with role-based targeting covering hospital technology leaders, pharmacy leaders, and clinical leaders. As a wholly-owned Wolters Kluwer subsidiary, Lexi-Comp no longer operates as a standalone entity; the legal name Lexi-Comp, Inc. persists within the corporate structure while the product brand is UpToDate Lexidrug.

Name

Lexi-Comp, Inc.

Legal name

Lexi-Comp, Inc.

Website

https://wolterskluwercdi.com

Company type

Private

Founded year

1978

Operating status

Acquired

Short description

Lexi-Comp, Inc. provides evidence-based drug referential content solutions to global healthcare institutions. Now operating as UpToDate Lexidrug within Wolters Kluwer's Health division, the company serves pharmacists, physicians, and clinicians with subscription-based medication decision support and embedded drug data products.

Ownership category

akta.pro rank

Product category

Clinical Decision Support Software

NAICS

Pharmacy Benefit Management and Other Third Party Administration of Insurance and Pension Funds (524292)

SIC

Services-Health Services (8000)

akta.pro primary industry

Pharmacy Benefit Management (PBM) & Formulary Management IT (HLACAKAD)

akta.pro secondary industries

Pharmacy Interoperability, Standards & Integration (FHIR/NCPDP) (HLACAKAO), Healthcare Terminology, Ontology & Code Set Management (SNOMED/LOINC/ICD/RxNorm) (HLACAIAF)

Keywords

• Drug decision support
• Clinical reference databases
• Healthcare information solutions
• Pharmaceutical content platforms
• Medication intelligence software

Headquarters

HQ city

Hudson

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Drug Referential Solutions: Lexi-Comp (now branded as UpToDate Lexidrug under Wolters Kluwer) provides drug referential content solutions to healthcare institutions, likely through subscription-based licensing models typical of enterprise healthcare software providers.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels2 records

Core offering

Lexi-Comp, Inc. provides evidence-based drug referential content solutions enabling healthcare professionals to make patient-specific medication decisions across the care continuum. The company offers drug information databases (UpToDate Lexidrug, formerly Lexicomp) and embedded drug data solutions (Medi-Span) integrated with clinical workflows at healthcare institutions globally.

Product overview

Lexi-Comp, Inc. (now operating as UpToDate Lexidrug under Wolters Kluwer's Health division) offers a portfolio of drug referential content solutions. The core offerings include UpToDate Lexidrug (formerly Lexicomp) for evidence-based drug decision support and Medi-Span for embedded drug data solutions used by healthcare institutions globally. These products are complemented by Simplifi+ Pharmacy Compliance for pharmacy regulatory compliance. The portfolio provides solutions for clinical decision support, medication intelligence, and pharmacy operations across the healthcare continuum.

Differentiator

Problem solved

Functional benefit

Brands

• UpToDate Lexidrug: Evidence-based drug referential solutions offered by Wolters Kluwer, formerly known as Lexicomp.

Products and services

• UpToDate Lexidrug (formerly Lexicomp) Evidence-based drug referential content solutions that provide healthcare professionals with comprehensive drug information to support clinical decision-making for individual patients.
• Medi-Span Suite of embedded drug data solutions designed for integration into healthcare systems, supporting medication-related decisions across the continuum of care. Includes Price Rx for pricing information.
• Simplifi+ Pharmacy Compliance Pharmacy compliance solution that helps pharmacies meet regulatory requirements and maintain compliance standards.

Named customers1 record

Segments1 record

Ideal customer profiles1 record

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature2 records

Recent moves5 records

Expansion highlights5 records

Emerging players

• DrugBank: DrugBank is a pharmaceutical knowledge database providing drug referential data, used by researchers, clinicians, and developers. It overlaps with Lexi-Comp in drug referential content and embedded drug data APIs.
• VisualDx: VisualDx provides clinical decision support focused on differential diagnosis and visual drug reactions, sold to the same enterprise healthcare customer base. Adjacent to Lexi-Comp's drug reference but complementary in clinical workflows.
• DynaMed (EBSCO): DynaMed is a clinical decision support tool used by clinicians at the point of care, with overlap in drug and treatment reference content. It competes for clinician-facing subscriptions alongside Lexicomp and Micromedex.
• Pharmacist's Letter / TRC Healthcare: TRC Healthcare (Pharmacist's Letter) provides evidence-based drug information and continuing education to pharmacists. It is comparable as a pharmacist-focused drug reference, though with stronger emphasis on education and CE.

Broad incumbents

• Wolters Kluwer UpToDate: UpToDate is the broader clinical decision support suite under the same Wolters Kluwer Health division that houses UpToDate Lexidrug. It is a sibling product, comparable in market and customer base, but broader in scope (general clinical content vs. drug-specific reference).
• Epic (drug content/decision support): Epic embeds drug decision support features within its EHR and competes for the same hospital IT budgets. While not a pure-play drug content vendor, it competes with Medi-Span's embedded drug data at the system integration layer.

Direct peers

• First Databank (FDB): FDB provides embedded drug data and clinical decision support solutions that integrate into EHRs and pharmacy systems. It directly competes with Medi-Span's embedded drug data offering and Lexi-Comp's clinical reference content.
• Elsevier Clinical Pharmacology: Elsevier's Clinical Pharmacology (formerly Gold Standard) provides drug referential content to hospitals and clinicians. It is one of the closest direct competitors to Lexicomp/UpToDate Lexidrug in drug reference and decision support.
• IBM Micromedex: IBM Micromedex is a direct peer, offering evidence-based drug referential and clinical decision support content to hospitals and pharmacists globally. It competes head-to-head with UpToDate Lexidrug (formerly Lexicomp) for enterprise drug information contracts.

Others

• Merative (formerly IBM Watson Health): Merative markets clinical decision support and evidence-based content offerings (historically including Micromedex-adjacent products) to hospitals and health systems. Comparable as a broader enterprise health IT and clinical content vendor with overlap to Lexi-Comp's drug decision support category.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks4 records

Key highlights5 records

Customer concentration

• YouTubeyoutube.com/@WoltersKluwerComms
• Facebookfacebook.com/wolterskluwer
• LinkedInlinkedin.com/company/wolters-kluwer-clinical-drug-information
• Instagraminstagram.com/_wolterskluwer

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Lexi-Comp, Inc.