BIO SYS

What BIO SYS does

BIOSYS Scientific Devices GmbH is a privately held German manufacturer of multiwell plate bioanalytical analyzers, headquartered in Karben, Germany and incorporated as a GmbH registered in Frankfurt am Main. Founded in 1986, the company has built its business around three core instrument platforms — the EAZYREADER 7000 (a 100% scalable ELISpot/Plaque reader upgradable on-site to single-cell and PBMC counting), the BIOREADER 7000 family in four variants (E, V, F, and F-z-i addressing enzymatic, visual, fluoro, and inverted-zoom applications respectively), and the BIOCOUNT 7000 (a 8-well strip reader delivering spot counts in 15-20 seconds). The technical differentiator is a patented dual telecentric illumination system (US 6,384,989 B1; US 6,597,522 B2; Euro Patent 1,122,576) that combines photometric intensity lighting with 3D telecentric illumination to prevent reflections and phantom spots, coupled with proprietary morphological algorithms for cluster separation and a Deep Machine Learning module trained on a proprietary corpus of tens of thousands of biomedical assay images for automated assay-type recognition.

The platform is sold for applications including ELISpot and Fluorospot cytokine quantification, plaque assays, TCID50, virus neutralization, cell infection assays, live/dead/apoptotic cell viability, transfection assessment, foci assays, colony counting, organoid imaging, and antibiotic potency testing — addressing SARS-CoV-2 research, vaccine and antiviral development, immunotherapy monitoring, cell and gene therapy workflows, and basic immunology. Revenue is generated almost entirely from hardware sales of the three reader families plus bundled professional services (qualified on-site installation, on-site training, and remote internet support), with optional 21 CFR Part 11 compliance software and LIS/LIMS import/export via barcode loading. Pricing is not publicly disclosed and is conducted via direct inquiry and distributor quotations. Domestic sales in Germany run direct from the Karben HQ; international sales run through a network of 13 named regional distributors covering 15+ countries (Australia, China/HK/Taiwan, France, India, Israel, Italy, Kenya/Rwanda/Uganda, Kuwait, New Zealand, Saudi Arabia, Singapore/Indonesia, Thailand, and USA/Canada/Mexico via the wholly-owned BIOSYS USA LLC subsidiary).

The customer base spans pharmaceutical and biotechnology R&D (Genentech, CureVac, Evotec, Astellas Gene Therapies, MedImmune, Valneva, Virogin, ACTREC), leading academic medical centers (Johns Hopkins School of Medicine, Stanford University, Karolinska University Hospital Solna, Charité Berlin, Technical University of Munich, Weizmann Institute), and public health institutions (CDC, Robert Koch Institute, China CDC Beijing). The company states "over 300 satisfied customers worldwide" on its homepage, suggesting a niche but global installed base developed over more than 25 years of operating history. Management consists of Anthony Fry as General Manager (Geschäftsführer) with Werner Freber listed as content responsible; no venture or private equity ownership is disclosed.

Name

BIO SYS

Legal name

BIOSYS Scientific Devices GmbH

Website

https://biosys.de

Company type

Private

Founded year

1986

Operating status

Operating

Headcount range

1–10 employees

Short description

BIOSYS Scientific Devices GmbH is a German manufacturer of multiwell plate bioanalytical analyzers (ELISpot, Fluorospot, plaque assays, cell counting) under the Bioreader, EazyReader, and Biocount platforms, serving 300+ pharmaceutical, academic, and government research customers across 15+ countries.

Ownership category

akta.pro rank

Product category

Laboratory Bioanalytical Equipment

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

SIC

Laboratory Analytical Instruments (3826)

akta.pro primary industry

Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE)

akta.pro secondary industry

Multiplex & High-Throughput Diagnostics Platforms (microarrays, digital PCR, lab automation-enabled assays) (HLAAALAL)

Keywords

• ELISpot readers
• Multiwell plate analyzers
• Plaque assay imaging
• PBMC cell counting
• Laboratory bioanalytical equipment

Headquarters

HQ city

Karben

HQ country

Germany

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Technology or R&D, Personnel, Marketing or Sales, Supply Chain

Revenue model

1. Laboratory Equipment Hardware Sales: BIOSYS generates revenue primarily from the sale of laboratory diagnostic instruments (Bioreader, EazyReader, and Biocount series). The company sells directly and through global distributors, with on-site installation, training, and support included with each device.
2. Professional Services (Installation, Training, Support): Qualified on-site installation and training are provided with each Bioreader purchase, along with on-site and internet remote support options.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels3 records

Core offering

BIOSYS Scientific Devices manufactures and sells multiwell plate bioanalytical analyzers — the BIOREADER, EAZYREADER, and BIOCOUNT product lines — that automate ELISpot, Fluorospot, plaque assay, cell viability, PBMC and single cell counting for pharmaceutical, biotechnology, academic, hospital, and government research laboratories. Instruments are sold bundled with on-site installation, training, and remote support, and are differentiated by patented dual telecentric illumination and deep machine learning image processing.

Product overview

BIO SYS Scientific Devices GmbH offers a portfolio of multiwell plate analyzing laboratory equipment for bioanalytical applications. The product line consists of three main reader platforms: EAZYREADER 7000 (the flagship 100% scalable Elispot/Plaque Reader with upgradability to single cell/PBMC counting), BIOREADER 7000 (available in four variants: E, V, F, and F-z-i for different applications from enzymatic to fluorescence), and BIOCOUNT 7000 (the world's first 8-well strip reader). All devices utilize the proprietary dual telecentric illumination system patented for better cytokine quantification and cluster separation. The portfolio targets applications including Elispot, Fluorospot, plaque assays, cell viability, infection assays, and SARS-CoV-2 research.

Differentiator

Problem solved

Functional benefit

Brands

• BIOREADER®: Laboratory multiwell plate analyzers for Elispot, Fluorospot, Plaque, and Fluoro-Plaque assays. Models include BIOREADER® 7000-E, 7000-V, 7000-F, and 7000-F-z-i.
• EAZYREADER®
• BIOCOUNT®

Products and services

• EAZYREADER 7000 100% scalable ELISpot/Plaque reader for pharmaceutical, biotech, and academic labs; upgradable on-site to a Single Cell/PBMC counter, combining white light illumination with dual telecentric lighting for cytokine quantification and cluster separation.
• BIOREADER 7000 -E Multiwell plate analyzer designed for enzymatic ELISpot applications in 96-well filter plates, counting 100% of the filter area with no losses due to exclusion of the outer border/filter region.
• BIOREADER 7000 -V Multiwell plate analyzer for non-fluorescence applications in 384-well to 6-well plates and Petri dishes, with white light illumination for enzymatic and visual plaque assays.
• BIOREADER 7000 -F Fluoro ELISpot/Plaque and enzymatic reader for 96 wells with high-power LED fluoro excitation, supporting dual-color fluorescence applications.
• BIOREADER 7000 -F-z-i Versatile inverted high-resolution zoom fluoro/VIS reader with micro and macro modes and high-power LED fluoro excitation, featuring three separate optical systems for Petri dishes, multiwell plates, and object slides.
• BIOCOUNT 7000 World's first multiwell plate reader for 8-well strips, providing ELISpot spot counts in 15-20 seconds with touchscreen operation, barcode scanning, and LIS/LIMS import, using the same dual telecentric illumination advantages as the BIOREADER line.

Quantifiable outcome

• Analysis time of 15-20 seconds for 8-well strips with Biocount 7000
• +3 more outcomes

Named customers17 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

AI capability2 records

Feature5 records

Partnerships

14 partnerships are on record, tiered standard and core.

• Hin Sci Pty Ltd.standardChannel Partner/ Reseller/ DistributorExclusive/named distributor for Australia. Handles sales and distribution of BIOSYS Scientific laboratory equipment (ELISpot readers, Fluorospot, plaque assay analyzers) within Australia.
• Bio-Excellence International TechstandardChannel Partner/ Reseller/ DistributorNamed distributor covering China, including Hong Kong and Taiwan. Responsible for distribution of BIOSYS products in the Chinese market.
• Serlabo TechnologiesstandardChannel Partner/ Reseller/ DistributorNamed distributor for France. Handles sales and distribution of BIOSYS laboratory equipment in the French market.
• Biotron Healthcare India Pvt. Ltd.standardChannel Partner/ Reseller/ DistributorNamed distributor for India. Responsible for distribution of BIOSYS Scientific products in the Indian market.
• Yesodhara Technologies (Pvt) Ltd.standardChannel Partner/ Reseller/ DistributorAdditional named distributor for India. Provides coverage for different regions or segments within the Indian market.
• Biotron Ltd.standardChannel Partner/ Reseller/ DistributorNamed distributor for Israel. Handles sales and distribution of BIOSYS laboratory equipment in the Israeli market.
• PANTEC S.r.l.standardChannel Partner/ Reseller/ DistributorNamed distributor for Italy. Handles sales and distribution of BIOSYS products in the Italian market.
• Faram E.A. LtdstandardChannel Partner/ Reseller/ DistributorNamed distributor for Kenya, Rwanda, and Uganda. Handles sales and distribution of BIOSYS Scientific equipment in East Africa.
• Advanced Technology CompanystandardChannel Partner/ Reseller/ DistributorNamed distributor for Kuwait. Handles sales and distribution of BIOSYS laboratory equipment in the Kuwaiti market.
• Total Lab Systems LimitedstandardChannel Partner/ Reseller/ DistributorNamed distributor for New Zealand. Handles sales and distribution of BIOSYS products in the New Zealand market.
• Techno OrbitsstandardChannel Partner/ Reseller/ DistributorNamed distributor for Saudi Arabia. Handles sales and distribution of BIOSYS laboratory equipment in the Saudi Arabian market.
• Yizeta Pte Ltd.standardChannel Partner/ Reseller/ DistributorNamed distributor for Singapore and Indonesia. Handles sales and distribution of BIOSYS Scientific products in Singapore and Indonesia.
• Prima Scientific Co., Ltd.standardChannel Partner/ Reseller/ DistributorNamed distributor for Thailand. Handles sales and distribution of BIOSYS laboratory equipment in the Thai market.
• BIOSYS USA LLCcoreChannel Partner/ Reseller/ DistributorWholly-owned subsidiary serving as the primary distributor for the USA, Canada, and Mexico markets. Provides direct sales and support for BIOSYS products in North America.

Scale indicators1 record

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Tecan: Swiss lab-automation and microplate-reader vendor offering multimode readers and cell-imaging systems integrated with liquid-handling robotics; relevant for immunoassay and cell-based labs where BIOSYS competes on imaging and quantification quality.
• Bio-Rad Laboratories: Large life-science tools company that historically supplied ELISpot automation and continues to offer immunoassay workflow products alongside a broad reagents and instruments portfolio, competing for the same lab budget dollars as BIOSYS Bioreader/EazyReader/Biocount.
• Revvity (formerly PerkinElmer Life Sciences): Provides multimode microplate readers, cell-imaging systems and immunoassay reagents across pharma/biotech labs; an established broad-line incumbent whose plate-reader range competes with BIOSYS for bioanalytical instrument budgets.
• Molecular Devices (Danaher): Danaher-owned manufacturer of high-content imaging and microplate readers (e.g., ImageXpress, SpectraMax) used for cell-based and immunoassay quantification; addresses overlapping pharma/biotech imaging workflows though its portfolio is much broader than ELISpot-specific.
• Thermo Fisher Scientific: Global life-science tools giant offering microplate readers, cell imaging and immunoassay workflows through brands such as Thermo Scientific and Applied Biosystems; competes with BIOSYS for the same pharma/biotech/CDC-type accounts via much larger installed base and direct sales force.

Emerging players

• Sartorius: German bioprocessing and lab-products company whose cell-analysis and lab-instruments portfolio (including post-BIA Separations acquisitions) increasingly touches immunoassay and cell-counting workflows competitive with BIOSYS EazyReader 7000's PBMC/viability extensions.
• Berthold Technologies: German specialty instrument maker offering microplate readers, luminometers and immunoassay detection systems relevant to virus neutralization and cytokine assays; targets similar academic and biotech customers and is comparable in size and Mittelstand profile.

Others

• Carl Zeiss Microscopy: Adjacent imaging-instrumentation leader supplying advanced microscopy and image-analysis platforms (e.g., Celldiscoverer) into cell-biology and immunology labs; not a direct ELISpot competitor but a comparably German premium-optics peer sharing the imaging-photonics DNA that BIOSYS' telecentric illumination leverages.

Direct peers

• CTL (Cellular Technology Limited): Direct competitor in automated ELISpot readers (ImmunoSpot S series) and T-cell/B-cell immunoassay analyzers, serving the same pharma, biotech, academic and immunological monitoring customers with similar hardware-plus-software reader platforms.
• AID Autoimmun Diagnostika GmbH: German manufacturer of multiwell plate readers (AID ELISpot reader, iSpot) for ELISpot, Fluorospot and viral neutralization assays; competes head-on with BIOSYS in pharma/biotech and academic immunoassay workflows and shares a German Mittelstand profile.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks7 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/bio-sys-gmbh

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BIO SYS