Name

BBD BioPhenix

Legal name

BBD BIOPHENIX S.L

Website

https://biobide.es

Company type

Private

Founded year

2005

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Product category

Preclinical CRO Services

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Toxicology & Safety Assessment CROs (GLP) (HLAGAAAC)

akta.pro secondary industries

Cell-Based & Potency Assays (Bioassays) (HLAGADAH), Laboratory Quality & GLP/GCLP Compliance (HLAGAKAK)

Keywords

• Preclinical drug discovery
• Zebrafish toxicity assays
• Contract research services
• Ecotoxicology testing
• GLP-compliant screening

Headquarters

HQ city

San Sebastian

HQ country

Spain

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Infrastructure, Operations, Technology or R&D, Marketing or Sales

Revenue model

1. Contract Research Services: CRO services for pharma, biotech, chemical, cosmetic and nutraceutical companies providing preclinical zebrafish-based toxicity and efficacy testing under GLP conditions.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels6 records

Core offering

BBD BioPhenix (Biobide) is a Contract Research Organization (CRO) providing specialized zebrafish-based preclinical testing services for drug discovery and safety assessment. The company delivers Good Laboratory Practice (GLP)-compliant toxicity and efficacy assays organized into general toxicity, specific-organ toxicity, ecotoxicology, and disease model categories. Services are conducted at its Miramon Technology Park facility in San Sebastian, which houses up to 80,000 adult zebrafish.

Product overview

Biobide (BBD BioPhenix) operates as a Contract Research Organization (CRO) providing specialized zebrafish-based testing services for preclinical drug discovery and safety assessment. The company's service portfolio includes Good Laboratory Practice (GLP)-compliant toxicity and efficacy assays organized into four main categories: General Toxicity Assays (Acutetox, Teratotox), Specific-Organ Toxicity Assays (Hepatotox, Cardiotox, Neurotox, Ototox, Immunotox, Muscle Toxicity, Kidney Toxicity, Multitox), Ecotoxicology Assays (EASZY Assay for estrogen pathway, Daphnia Immobilization, Algae Growth Inhibition, Thyroid Disruption), and Efficacy/Disease Models (Antioxidation, Regeneration, Melanin Quantification, Cancer Angiogenesis, Neurodegenerative/Rare Diseases, ALS Models, Sperm Quality, Disease Model Generation, Target Validation). The company also offers specialized reproductive services including zebrafish sperm cryopreservation and in vitro fertilization. All services are conducted at the company's Miramon Technology Park facility in San Sebastian, which houses up to 80,000 adult zebrafish.

Differentiator

Problem solved

Functional benefit

Products and services

• Acutetox Assay General toxicity screening assay using zebrafish embryos to assess acute toxic effects of compounds, available in general and ecotoxicology variants.
• Teratotox Assay General toxicity assay evaluating teratogenic effects (developmental malformations) in zebrafish embryos.
• Cardiotox Assay Specific toxicity assay evaluating cardiovascular toxicity effects in zebrafish models.
• Neurotox Assay Specific toxicity assay assessing neurotoxic effects using zebrafish models.
• Hepatotox Assay Specific toxicity assay evaluating hepatotoxicity (liver toxicity) in zebrafish models.
• Nephrotox/Kidney Toxicity Assay Specific toxicity assay assessing kidney toxicity effects in zebrafish models.
• Ototox Assay Specific toxicity assay assessing ototoxicity (hearing/ear toxicity) in zebrafish models.
• Immunotox Assay Specific toxicity assay evaluating immunotoxicity effects in zebrafish models.
• Muscle Toxicity Assay Specific toxicity assay assessing muscle toxicity effects in zebrafish models.
• Multitox Assay Comprehensive multi-parameter toxicity assessment screening multiple toxicity endpoints simultaneously in zebrafish.
• EASZY Assay (Estrogen Pathway) Ecotoxicology assay evaluating estrogen pathway disruption using zebrafish, specifically designed for endocrine disruptor screening.
• Daphnia Immobilization Test Ecotoxicology assay assessing acute toxicity to Daphnia (water fleas) for environmental hazard characterization.
• Microplate Alga Growth Inhibition Test Ecotoxicology assay evaluating effects on algal growth for environmental toxicity assessment.
• Thyroid Disruption Assay Ecotoxicology assay assessing thyroid endocrine disruption effects in zebrafish models.
• Zebrafish Sperm Cryopreservation and In Vitro Fertilization Specialized reproductive biology service for zebrafish strain preservation and controlled breeding experiments.
• Antioxidation Assay Efficacy assay evaluating antioxidant properties and effects of test compounds.
• Regeneration Assay Efficacy assay assessing tissue regeneration capacity in zebrafish models.
• Melanin Quantification Assay Efficacy assay for measuring melanin content and pigmentation effects in zebrafish.
• Cancer Angiogenesis Inhibition Assay Efficacy assay evaluating anti-angiogenic properties of compounds for cancer therapeutic development.
• Neurodegenerative and Rare Diseases Models Efficacy and disease model services for studying neurodegenerative disorders and rare diseases using zebrafish models.
• Zebrafish Models for Amyotrophic Lateral Sclerosis (ALS) Specific disease model service using zebrafish to study ALS pathophysiology and test therapeutic candidates.
• Sperm Quality Assessment Reproductive toxicology service evaluating zebrafish sperm quality parameters.
• Disease Model Generation Custom zebrafish disease model generation service for creating validated disease models for preclinical research.
• Target Validation Research service for validating therapeutic targets using zebrafish models in early drug discovery.

Quantifiable outcome

• Reduced drug development failure rate through early toxicity screening

Named customers7 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

14 partnerships are on record, tiered core and minor.

• Biatgroup (formerly Bionaturis Group)coreStrategic or Co-development Partner · 1 January 2014Parent company. Biobide was acquired by Bionaturis Group in 2014. In 2018, Bionaturis acquired ADL Biopharma through a reverse acquisition to form Biatgroup. Biatgroup is a biotech European leader focused on R&D and manufacturing high-value fermentation products, listed on MaB (ticker BST).
• ASEBIOminorOthersSpanish biotechnology association membership providing networking and industry representation.
• Basque Health ClusterminorOthersRegional health cluster membership for Basque biotech ecosystem collaboration.
• BioBasqueminorOthersBasque biotechnology platform membership for regional industry collaboration.
• DIA GlobalminorOthersGlobal regulatory science organization membership supporting regulatory affairs expertise.
• ETSOCminorOthersEmbryo Toxicology Society membership for developmental and reproductive toxicology expertise.
• EuFishBiomedminorOthersEuropean Consortium for Biomedical Sciences using fish models.
• HOT (Human Occupational Toxicology Special Interest Group)minorOthersSpecial interest group within the Society of Toxicology for occupational toxicology.
• LogoCILcareminorOthersNanomedicine and otology industry association membership.
• Safety Pharmacology Society (SPS)minorOthersInternational society membership for safety pharmacology expertise.
• SETACminorOthersSociety of Environmental Toxicology and Chemistry membership for ecotoxicology expertise.
• Society of Toxicology (SOT)minorOthersLeading toxicology society membership for scientific networking and expertise.
• ZHA (Zebrafish Husbandry Association)minorOthersInternational association for zebrafish colony management and husbandry standards.
• Hazitek Program (Basque Government)minorStrategic or Co-development PartnerBasque government R&D support programs including Hazitek 2024, Hazitek 2025, DanioBit 2023 projects for zebrafish technology development.

Scale indicators3 records

Recent moves8 records

Expansion highlights5 records

Broad incumbents

• Toxikon: Preclinical contract research organization providing toxicology and medical device testing services. Comparable incumbents competing in outsourced preclinical safety assessment.
• Charles River Laboratories: Global preclinical CRO offering end-to-end safety assessment, including early-stage toxicology and alternative models. Represents the large incumbent against whom Biobide competes for outsourced preclinical contracts.
• WuXi AppTec: Global CRO/CDMO with extensive preclinical toxicology and safety assessment capacity. Sets the scale benchmark for outsourced preclinical services and competes for the same pharma clients.
• Labcorp Early Development Services: Large-scale preclinical CRO providing safety pharmacology and toxicology services globally. Competes broadly for outsourced safety-assessment work, including alternative-model studies.
• Evotec (Zebrafish / Preclinical): Mid-to-large discovery CRO with zebrafish-related preclinical capabilities alongside broader discovery and safety-assessment services. Comparable as a multi-modal preclinical CRO with zebrafish as one offering.

Emerging players

• Sai Life Sciences: India-headquartered preclinical CRO expanding toxicology and safety assessment services for global pharma. Comparable emerging player offering outsourced preclinical capabilities at competitive cost.
• Bioneer Inc. Korean biotech company offering zebrafish embryo-based toxicology testing services. Emerging geographic peer with similar zebrafish-only CRO model in Asia.
• InDanio Bioscience: EU-focused zebrafish toxicology and drug-screening service provider. Comparable emerging niche player focused on regulatory toxicology using zebrafish models.

Direct peers

• ZeClinics: Barcelona-based zebrafish CRO offering toxicity, efficacy, and disease-model services for pharma and biotech. Closest direct competitor to Biobide on model organism, geography, and service mix.
• Phylonix Services International: Massachusetts-based CRO specializing in zebrafish-based drug discovery and toxicology assays. Directly comparable as a zebrafish-only CRO serving global pharma clients.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key highlights7 records

Customer concentration

• Xx.com/Biobide_
• YouTubeyoutube.com/channel/UCE979rIc4g09AF2LBr7uoZg
• Facebookfacebook.com/Biobide-1286387971453667
• LinkedInlinkedin.com/company/biobide

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BBD BioPhenix