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GORTEC

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uuid002esrv

Namestring
GORTEC
Legal namestring
GORTEC - Groupe d'Oncologie Radiothérapie Tête Et Cou
Websiteurl
gortec.net
Company typeenum
Private
Founded yearint
1994
Descriptiontext

GORTEC (Groupe d'Oncologie Radiothérapie Tête Et Cou) is a French academic clinical research cooperative group founded in 1994 and headquartered in Tours, France. It coordinates multi-center clinical and biological studies — including Phase III trials — in head and neck oncology and radiotherapy, operating under a French association loi 1901 / groupement d'intérêt scientifique structure governed by its member researchers and academic medical centers rather than external shareholders. The organization manages a portfolio of 15+ active trials (ILLUMINE, IDEAL, TATIANA, AdCC, XXL, NIVOPOST-OP, StereoPostOp, SANTAL, Pembrorad, OMET, SALTORL, TPFmORL, REWRITe, SIMPA01, REACH) with regulatory footprint in France, Belgium, and Spain, and publishes the Journal du GORTEC and trial-specific newsletters as its primary member-facing communications. GORTEC's recent scientific milestone was the ASCO 2025 plenary presentation of NIVOPOST-OP results demonstrating 63% disease-free survival at 3 years with post-operative nivolumab, an +11% absolute cure-rate improvement over control.

GORTEC's revenue mechanics are non-commercial: it does not sell products or services at list price and is funded through a mix of member contributions, public and institutional research grants, and pharmaceutical industrial-partner co-sponsorship. Its named industrial sponsors include AstraZeneca, Bicara Therapeutics, Leo Pharma, Merck Group, Merck MSD, Nanobiotix, and Summit Therapeutics. Distribution and outreach occur through medical congresses (ASCO, ESTRO), peer-reviewed publications, internal newsletters, the LinkedIn professional channel, and joint annual meetings with Intergroupe ORL (IGORL). GORTEC's primary "customer" base is oncology professionals — radiation oncologists, medical oncologists, and head and neck surgeons — across European academic medical centers.

Its technology stack is conventional for an academic cooperative group: trial-protocol design, multi-center coordination, translational research workflows, and a literature-watch (veille bibliographique) service. No proprietary software products, APIs, AI/ML systems, or commercial platform components are disclosed in the source data.

Short descriptiontext

GORTEC is a French academic clinical research cooperative group that designs and coordinates multi-center Phase III clinical trials in head and neck oncology across France, Belgium, and Spain, funded by membership dues, grants, and pharmaceutical sponsorships.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
11–50
akta.pro rankint
HeadquartersTours, France
HQ citystring
Tours
HQ countrystring
France
HQ regionstring
Europe
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
clinical research coordination, head and neck oncology, radiation oncology trials, cooperative research group, oncology clinical trials
Industry3 codes
1Medical Oncology
CodeHLAKAFABPrimaryYes
2Clinical Research & Trial Central Laboratories
CodeHLAFAMALPrimaryNo
3Clinical Trial Site Operations & Study Coordination
CodeHLAGACAEPrimaryNo
NAICS code1 code
  • Other Scientific and Technical Consulting Services54169
SIC code1 code
  • Services-Commercial Physical & Biological Research8731
Product category
Oncology Clinical Research Services
Marketing channels4 records

Each record includes

Title, Type, Stage, Description, Source

Cost components5 values
Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure
GTM typeB2B
B2B
Offering typeServices
Services
Core offering1 text field

GORTEC is a French academic cooperative group that coordinates and manages multi-center clinical trials and biological studies in head and neck oncology and radiation oncology. The organization designs, initiates, and oversees Phase III and translational research studies, collaborating with academic medical centers and pharmaceutical industrial partners across France, Belgium, and Spain. It also publishes clinical research findings through its Journal du GORTEC and trial-specific newsletters.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 value
  • 63% disease-free survival at 3 years with nivolumab post-operative treatment in NIVOPOST-OP trial (+11% of patients cured with immunotherapy)
Product overview1 text field

GORTEC (Groupe d'Oncologie Radiothérapie Tête Et Cou) is a French clinical research cooperative group specializing in head and neck oncology. Rather than a software product company, GORTEC coordinates and manages clinical trials as its primary activity. The organization offers clinical research coordination services, publishes scientific journals and trial-specific newsletters, and maintains a portfolio of ongoing clinical trials in radiotherapy and head and neck cancer treatment. Key offerings include the Journal du GORTEC publication and Clinical Trial Newsletters for studies such as ILLUMINE, ADCC, NIVOPOST-OP, and others.

Product and service4 records
1GORTEC Clinical Research Coordination Services
CategoryClinical Research Coordination
Description

Coordination and management of clinical studies in head and neck oncology, including radiotherapy research. The organization serves as a cooperative group (Groupe Coopérateur) that designs, initiates, and oversees multi-center clinical trials across France and international sites for oncology professionals, academic medical centers, and pharmaceutical partners.

2ILLUMINE Trial
CategoryClinical Trial
Description

Phase III clinical trial in head and neck cancer sponsored by GORTEC in collaboration with Summit Therapeutics. Regulatory approvals obtained for activation in France, Belgium, and Spain.

3Ongoing Clinical Trials Portfolio
CategoryClinical Trials
Description

Active Phase III clinical trials including ILLUMINE (2024-04) in head and neck cancer, IDEAL (2024-03), TATIANA (2024-01), AdCC (2023-01), and XXL (2022-01), spanning various stages of oncology research.

4Journal du GORTEC
CategoryScientific Publication
Description

Periodical journal published by GORTEC covering clinical trial results, research discussions, and updates from the head and neck oncology field. Issues include Journal N°31 (October 2025) and Journal N°32 (April 2026).

Scale indicator3 records

Each record includes

Type, Value, Description, Source

Partnership8 partners
Strategic tierCoreTypeStrategic or Co-development PartnerAnnounced on2026-02-23
Description

GORTEC is sponsoring the ILLUMINE Phase III trial in head and neck cancer in collaboration with Summit Therapeutics. The trial has received regulatory approvals to start in France, Belgium, and Spain.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

AstraZeneca is listed as an industrial partner of GORTEC. The partnership supports clinical trials in head and neck oncology conducted by the cooperative group.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Bicara Therapeutics is listed as an industrial partner of GORTEC, supporting the group's clinical research activities in head and neck cancer.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Leo Pharma is listed as an industrial partner of GORTEC, contributing to the cooperative group's oncology research programs.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Merck Group is listed as an industrial partner of GORTEC, supporting clinical research activities.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Merck MSD (Merck Sharp & Dohme) is listed as an industrial partner of GORTEC for oncology clinical trials.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Nanobiotix is listed as an industrial partner of GORTEC, contributing to head and neck cancer research programs.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

GORTEC collaborates with IGORL (Intergroupe ORL - Head and Neck Intergroup) on joint professional meetings and research initiatives. The organizations hold combined annual meetings.

Recent move7 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
TypeBroad incumbent
Description

UNICANCER is the French federation of Comprehensive Cancer Centers (CLCCs) and runs large-scale clinical research programs across all major tumor types. It is a broad incumbent peer to GORTEC within the French oncology research ecosystem, with overlapping investigator networks and sponsor relationships.

2European Organisation for Research and Treatment of Cancer (EORTC) - re-listed for emphasis
TypeDirect peer
Description

Selected as a key peer representing the international cooperative oncology group tier that GORTEC competes against for cross-border trial mandates and pharma sponsorship in head and neck oncology.

TypeDirect peer
Description

EORTC is the leading European academic clinical research cooperative group in oncology. It is the most direct peer to GORTEC, conducting multi-center oncology trials across Europe with similar cooperative group governance and pharma-partnered funding model, though operating at significantly larger scale and broader therapeutic scope.

TypeDirect peer
Description

NRG Oncology is a US-based cooperative group focused on radiation oncology and head and neck cancers. It is a direct peer to GORTEC in terms of radiation oncology and head and neck cancer trial focus, though operating across North America with NCI funding support.

TypeBroad incumbent
Description

ECOG-ACRIN is a large US-based NCI-sponsored cooperative group conducting oncology clinical trials. Comparable to GORTEC as a multi-institutional academic cooperative group, though operating at substantially larger scale across all major tumor types.

TypeDirect peer
Description

GERCOR is a French academic cooperative group conducting clinical trials in oncology with a similar multi-center, pharma-sponsored model. It is comparable to GORTEC as a national cooperative peer, though focused on different tumor types (mainly gastrointestinal and breast).

TypeDirect peer
Description

FFCD is a French cooperative group dedicated to digestive oncology clinical research. Comparable to GORTEC as a French national cooperative oncology group with similar governance and pharma-sponsored multi-center trial operations, though focused on GI cancers.

TypeDirect peer
Description

TROG is the Trans-Tasman Radiation Oncology Group, an Australian/New Zealand cooperative group specializing in radiation oncology clinical trials. Directly comparable to GORTEC for its radiation oncology focus, multi-center trial model, and academic cooperative governance.

TypeDirect peer
Description

IFCT is a French francophone cooperative group conducting clinical trials in thoracic oncology. It is directly comparable to GORTEC as a national French intergroup with the same cooperative governance, pharma-partnered trial model, and member-driven structure, though focused on lung cancer.

TypeDirect peer
Description

ARCAGY-GINECO is a French cooperative group focused on gynecological oncology clinical research. Directly comparable to GORTEC as a French national cooperative group with similar member-driven governance and pharma-partnered trial operations.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat5 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights7 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment2 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
No
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles2 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

GORTEC

Oncology Clinical Research Servicesgortec.net

GORTEC is a French academic clinical research cooperative group that designs and coordinates multi-center Phase III clinical trials in head and neck oncology across France, Belgium, and Spain, funded by membership dues, grants, and pharmaceutical sponsorships.

What GORTEC does

GORTEC (Groupe d'Oncologie Radiothérapie Tête Et Cou) is a French academic clinical research cooperative group founded in 1994 and headquartered in Tours, France. It coordinates multi-center clinical and biological studies — including Phase III trials — in head and neck oncology and radiotherapy, operating under a French association loi 1901 / groupement d'intérêt scientifique structure governed by its member researchers and academic medical centers rather than external shareholders. The organization manages a portfolio of 15+ active trials (ILLUMINE, IDEAL, TATIANA, AdCC, XXL, NIVOPOST-OP, StereoPostOp, SANTAL, Pembrorad, OMET, SALTORL, TPFmORL, REWRITe, SIMPA01, REACH) with regulatory footprint in France, Belgium, and Spain, and publishes the Journal du GORTEC and trial-specific newsletters as its primary member-facing communications. GORTEC's recent scientific milestone was the ASCO 2025 plenary presentation of NIVOPOST-OP results demonstrating 63% disease-free survival at 3 years with post-operative nivolumab, an +11% absolute cure-rate improvement over control.

GORTEC's revenue mechanics are non-commercial: it does not sell products or services at list price and is funded through a mix of member contributions, public and institutional research grants, and pharmaceutical industrial-partner co-sponsorship. Its named industrial sponsors include AstraZeneca, Bicara Therapeutics, Leo Pharma, Merck Group, Merck MSD, Nanobiotix, and Summit Therapeutics. Distribution and outreach occur through medical congresses (ASCO, ESTRO), peer-reviewed publications, internal newsletters, the LinkedIn professional channel, and joint annual meetings with Intergroupe ORL (IGORL). GORTEC's primary "customer" base is oncology professionals — radiation oncologists, medical oncologists, and head and neck surgeons — across European academic medical centers.

Its technology stack is conventional for an academic cooperative group: trial-protocol design, multi-center coordination, translational research workflows, and a literature-watch (veille bibliographique) service. No proprietary software products, APIs, AI/ML systems, or commercial platform components are disclosed in the source data.

GORTEC firmographics

Firmographics
Name
GORTEC
Legal name
GORTEC - Groupe d'Oncologie Radiothérapie Tête Et Cou
Website
https://gortec.net
Company type
Private
Founded year
1994
Operating status
Operating
Headcount range
11–50 employees
Short description
GORTEC is a French academic clinical research cooperative group that designs and coordinates multi-center Phase III clinical trials in head and neck oncology across France, Belgium, and Spain, funded by membership dues, grants, and pharmaceutical sponsorships.
Ownership category
akta.pro rank

GORTEC industry classification

Industry
Product category
Oncology Clinical Research Services
NAICS
Other Scientific and Technical Consulting Services (54169)
SIC
Services-Commercial Physical & Biological Research (8731)
akta.pro primary industry
Medical Oncology (HLAKAFAB)
akta.pro secondary industries
Clinical Research & Trial Central Laboratories (HLAFAMAL), Clinical Trial Site Operations & Study Coordination (HLAGACAE)

Keywords

  • Clinical research coordination
  • Head and neck oncology
  • Radiation oncology trials
  • Cooperative research group
  • Oncology clinical trials

Where GORTEC is headquartered

Location

Headquarters

HQ city
Tours
HQ country
France
HQ region
Europe

Offices1 record

Markets served

GORTEC business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Marketing channels4 records

GORTEC product offering

Product offering

Core offering

GORTEC is a French academic cooperative group that coordinates and manages multi-center clinical trials and biological studies in head and neck oncology and radiation oncology. The organization designs, initiates, and oversees Phase III and translational research studies, collaborating with academic medical centers and pharmaceutical industrial partners across France, Belgium, and Spain. It also publishes clinical research findings through its Journal du GORTEC and trial-specific newsletters.

Product overview

GORTEC (Groupe d'Oncologie Radiothérapie Tête Et Cou) is a French clinical research cooperative group specializing in head and neck oncology. Rather than a software product company, GORTEC coordinates and manages clinical trials as its primary activity. The organization offers clinical research coordination services, publishes scientific journals and trial-specific newsletters, and maintains a portfolio of ongoing clinical trials in radiotherapy and head and neck cancer treatment. Key offerings include the Journal du GORTEC publication and Clinical Trial Newsletters for studies such as ILLUMINE, ADCC, NIVOPOST-OP, and others.

Differentiator

Problem solved

Functional benefit

Products and services

  • GORTEC Clinical Research Coordination Services Coordination and management of clinical studies in head and neck oncology, including radiotherapy research. The organization serves as a cooperative group (Groupe Coopérateur) that designs, initiates, and oversees multi-center clinical trials across France and international sites for oncology professionals, academic medical centers, and pharmaceutical partners.
  • ILLUMINE Trial Phase III clinical trial in head and neck cancer sponsored by GORTEC in collaboration with Summit Therapeutics. Regulatory approvals obtained for activation in France, Belgium, and Spain.
  • Ongoing Clinical Trials Portfolio Active Phase III clinical trials including ILLUMINE (2024-04) in head and neck cancer, IDEAL (2024-03), TATIANA (2024-01), AdCC (2023-01), and XXL (2022-01), spanning various stages of oncology research.
  • Journal du GORTEC Periodical journal published by GORTEC covering clinical trial results, research discussions, and updates from the head and neck oncology field. Issues include Journal N°31 (October 2025) and Journal N°32 (April 2026).

Quantifiable outcome

  • 63% disease-free survival at 3 years with nivolumab post-operative treatment in NIVOPOST-OP trial (+11% of patients cured with immunotherapy)

Companies that use GORTEC

Customer profile

Segments2 records

Ideal customer profiles2 records

GORTEC technology and API

Technology

Technology focussed No

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

GORTEC partnerships and signals

Strategic signal

Partnerships

Eight partnerships are on record, tiered core.

  • Summit TherapeuticscoreStrategic or Co-development Partner · 23 February 2026GORTEC is sponsoring the ILLUMINE Phase III trial in head and neck cancer in collaboration with Summit Therapeutics. The trial has received regulatory approvals to start in France, Belgium, and Spain.
  • AstraZenecacoreStrategic or Co-development PartnerAstraZeneca is listed as an industrial partner of GORTEC. The partnership supports clinical trials in head and neck oncology conducted by the cooperative group.
  • Bicara TherapeuticscoreStrategic or Co-development PartnerBicara Therapeutics is listed as an industrial partner of GORTEC, supporting the group's clinical research activities in head and neck cancer.
  • Leo PharmacoreStrategic or Co-development PartnerLeo Pharma is listed as an industrial partner of GORTEC, contributing to the cooperative group's oncology research programs.
  • Merck GroupcoreStrategic or Co-development PartnerMerck Group is listed as an industrial partner of GORTEC, supporting clinical research activities.
  • Merck MSDcoreStrategic or Co-development PartnerMerck MSD (Merck Sharp & Dohme) is listed as an industrial partner of GORTEC for oncology clinical trials.
  • NanobiotixcoreStrategic or Co-development PartnerNanobiotix is listed as an industrial partner of GORTEC, contributing to head and neck cancer research programs.
  • Intergroupe ORL (IGORL)coreStrategic or Co-development PartnerGORTEC collaborates with IGORL (Intergroupe ORL - Head and Neck Intergroup) on joint professional meetings and research initiatives. The organizations hold combined annual meetings.

Scale indicators3 records

Recent moves7 records

Expansion highlights4 records

GORTEC competitors and assessment

Company assessment

Broad incumbents

  • UNICANCER: UNICANCER is the French federation of Comprehensive Cancer Centers (CLCCs) and runs large-scale clinical research programs across all major tumor types. It is a broad incumbent peer to GORTEC within the French oncology research ecosystem, with overlapping investigator networks and sponsor relationships.
  • ECOG-ACRIN Cancer Research Group: ECOG-ACRIN is a large US-based NCI-sponsored cooperative group conducting oncology clinical trials. Comparable to GORTEC as a multi-institutional academic cooperative group, though operating at substantially larger scale across all major tumor types.

Direct peers

  • European Organisation for Research and Treatment of Cancer (EORTC) - re-listed for emphasis: Selected as a key peer representing the international cooperative oncology group tier that GORTEC competes against for cross-border trial mandates and pharma sponsorship in head and neck oncology.
  • EORTC: EORTC is the leading European academic clinical research cooperative group in oncology. It is the most direct peer to GORTEC, conducting multi-center oncology trials across Europe with similar cooperative group governance and pharma-partnered funding model, though operating at significantly larger scale and broader therapeutic scope.
  • NRG Oncology: NRG Oncology is a US-based cooperative group focused on radiation oncology and head and neck cancers. It is a direct peer to GORTEC in terms of radiation oncology and head and neck cancer trial focus, though operating across North America with NCI funding support.
  • GERCOR: GERCOR is a French academic cooperative group conducting clinical trials in oncology with a similar multi-center, pharma-sponsored model. It is comparable to GORTEC as a national cooperative peer, though focused on different tumor types (mainly gastrointestinal and breast).
  • FFCD (Fédération Francophone de Cancérologie Digestive): FFCD is a French cooperative group dedicated to digestive oncology clinical research. Comparable to GORTEC as a French national cooperative oncology group with similar governance and pharma-sponsored multi-center trial operations, though focused on GI cancers.
  • TROG Cancer Research: TROG is the Trans-Tasman Radiation Oncology Group, an Australian/New Zealand cooperative group specializing in radiation oncology clinical trials. Directly comparable to GORTEC for its radiation oncology focus, multi-center trial model, and academic cooperative governance.
  • IFCT (Intergroupe Francophone de Cancérologie Thoracique): IFCT is a French francophone cooperative group conducting clinical trials in thoracic oncology. It is directly comparable to GORTEC as a national French intergroup with the same cooperative governance, pharma-partnered trial model, and member-driven structure, though focused on lung cancer.
  • ARCAGY-GINECO: ARCAGY-GINECO is a French cooperative group focused on gynecological oncology clinical research. Directly comparable to GORTEC as a French national cooperative group with similar member-driven governance and pharma-partnered trial operations.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

GORTEC social profiles

Digital presence

GORTEC financial estimates

Financial estimate

Revenue estimate

Valuation estimate

GORTEC leadership team

Management profile

Number of profiles

Profiles2 records

GORTEC funding detail

Funding detail

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

GORTEC M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about GORTEC

What does GORTEC do?

GORTEC is a French academic cooperative group that coordinates and manages multi-center clinical trials and biological studies in head and neck oncology and radiation oncology. The organization designs, initiates, and oversees Phase III and translational research studies, collaborating with academic medical centers and pharmaceutical industrial partners across France, Belgium, and Spain. It also publishes clinical research findings through its Journal du GORTEC and trial-specific newsletters.

Is GORTEC a public or private company?

GORTEC is a private company. It is classified as nonprofit foundation owned and is currently operating.

When was GORTEC founded?

GORTEC was founded in 1994. It employs 11 to 50 people.

Where is GORTEC based?

GORTEC is headquartered in Tours, France, in the Europe region.

Who are GORTEC's main competitors?

Broad incumbents on record are UNICANCER and ECOG-ACRIN Cancer Research Group. Direct peers are European Organisation for Research and Treatment of Cancer (EORTC) - re-listed for emphasis, EORTC, NRG Oncology, GERCOR, FFCD (Fédération Francophone de Cancérologie Digestive), TROG Cancer Research, IFCT (Intergroupe Francophone de Cancérologie Thoracique) and ARCAGY-GINECO.

Does GORTEC have an API?

No public API is recorded for GORTEC.

What industry is GORTEC in?

GORTEC's product category is Oncology Clinical Research Services. Its primary akta.pro industry code is HLAKAFAB, Medical Oncology, with a secondary code of HLAFAMAL, Clinical Research & Trial Central Laboratories. Its NAICS code is 54169 and its SIC code is 8731.

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Live signals
EIN PresswireNETRIS Pharma Secures €7.25 Million in Horizon Europe Funding to Advance Phase 2b Clinical Trial in Head and Neck CancerNETRIS Pharma secured €7.25 million in Horizon Europe funding to conduct a Phase 2b randomized trial of NP137 in head and neck squamous cell carcinoma. The trial, led by Dr. Jérôme Fayette with GORTEC, will be conducted across France and Spain. The funding follows the positive Phase 2 ImmunoNET study results.BioSpaceSummit Therapeutics Reports Financial Results and Operational Progress for the First Quarter Ended March 31, 2026Summit Therapeutics reported Q1 2026 financial results and clinical progress for ivonescimab. GAAP net loss was $189.4 million, up from $62.9 million a year earlier, with operating expenses rising to $195.2 million. The company will present HARMONi-6 overall survival data at ASCO 2026 and host a conference call on June 1.Business Wire BlogSummit Therapeutics Reports Financial Results and Operational Progress for the First Quarter Ended March 31, 2026Summit Therapeutics Inc. reported Q1 2026 financial results with a GAAP net loss of $189.4 million compared to $62.9 million in Q1 2025, driven by expanded clinical development costs for ivonescimab, while holding $598.7 million in cash and equivalents. The FDA accepted the company's Biologics License Application for ivonescimab in EGFR-mutated non-squamous NSCLC with a PDUFA goal date of November 14, 2026, and positive Phase III updates include HARMONi-6 overall survival data slated for ASCO 2026 Plenary Session and an interim analysis recommendation for HARMONi-3 to continue as planned. The company continues advancing multiple global Phase III trials and has entered clinical collaborations with Revolution Medicines, GSK, and GORTEC to expand ivonescimab's development across additional solid tumor indications.PR NewswireLe GORTEC annonce le succès d'un nouvel essai pour le traitement du cancer de la tête et du couThe GORTEC cooperative group announced that its randomized Phase 3 trial NIVO POST OP (GORTEC 2018-01) evaluating Bristol Myers Squibb's anti-PD-1 drug nivolumab as an adjuvant component alongside cisplatin-radiotherapy in high-risk patients with resected locally advanced head and neck squamous cell carcinoma (LA-SCCHN) met its primary endpoint, demonstrating a statistically significant and clinically meaningful improvement in disease-free survival (DFS). The 680-patient study showed that adding nivolumab to the standard cisplatin-radiotherapy regimen improved DFS outcomes compared to radiotherapy plus cisplatin alone, with a safety profile consistent with prior studies and similar adherence to standard treatment across both arms. The investigators noted this marks the first time in decades that a treatment has demonstrated superiority over the standard cisplatin-radiotherapy regimen for this patient population, with a trend toward improved overall survival also observed as a secondary endpoint.PR NewswireGORTEC Announces New Trial Success for Head and Neck Cancer TreatmentGORTEC, a head and neck oncology research group based in France, announced positive results from its Phase 3 NIVOPOSTOP trial evaluating Bristol Myers Squibb's nivolumab as an adjuvant treatment for resected locally advanced head and neck squamous cell carcinoma patients with high relapse risk. The trial met its primary endpoint of disease-free survival improvement, showing a statistically significant and clinically meaningful benefit compared to standard-of-care cisplatin-radiotherapy alone in 680 randomized patients. Investigators described the findings as potentially practice-changing, representing the first therapy in decades to demonstrate superiority over the standard cisplatin-radiotherapy regimen in this patient population.PR NewswireGORTEC Announces New Trial Success for Head and Neck Cancer TreatmentGORTEC announced that its randomized Phase 3 NIVOPOSTOP GORTEC 2018-01 trial evaluating nivolumab as a post-operative treatment for resected locally advanced head and neck cancer met its primary endpoint of Disease-Free Survival, showing statistically significant and clinically meaningful improvement over standard-of-care cisplatin-radiotherapy. The trial enrolled 680 high-risk patients who were randomized after surgery to receive either standard treatment alone or with the addition of nivolumab. Investigators described the results as potentially practice-changing, noting it is the first time in decades a therapy demonstrated superiority over the standard cisplatin-radiotherapy regimen in this patient population.PR NewswireGORTEC anuncia el éxito de un nuevo ensayo para el tratamiento del cáncer de cabeza y cuelloGORTEC announced that its randomized Phase 3 trial NIVOPOSTOP GORTEC 2018-01 met its primary endpoint of disease-free survival, demonstrating a statistically significant and clinically meaningful improvement in high-risk patients with resected locally advanced head and neck squamous cell carcinoma treated with nivolumab added to standard radiotherapy and cisplatin. The study enrolled 680 patients and the safety profile of nivolumab was consistent with prior reports. Researchers noted this is the first time in decades that a therapy has shown superiority over the standard chemoradiotherapy regimen specifically in patients of African ancestry, with the potential to change clinical practice pending final overall survival analysis.GlobeNewswireOxford BioTherapeutics announces Phase 1b trial in collaboration with GORTEC to investigate OBT076 in Adenoid Cystic Carcinoma (ACC) of the head and neckOxford BioTherapeutics announced a Phase 1b trial with GORTEC to test OBT076 in recurrent or metastatic adenoid cystic carcinoma of the head and neck. The trial will evaluate OBT076 as monotherapy and with balstilimab, targeting CD205 overexpressed in ~80% of ACC samples. The collaboration aims to provide evidence for potential fast-track approval given the disease's unmet need.