Simbiose

What Simbiose does

Simbiose Agro is a Brazilian agricultural biotechnology company founded in 2007 and headquartered in Cruz Alta, Rio Grande do Sul. It develops and manufactures microbiological agricultural inputs — biodefensives (biofungicides, bioinsecticides, bionematicides), inoculants for biological nitrogen fixation, fertilizers, and adjuvants — based on proprietary and co-developed strains of bacteria, fungi, and viruses. The company claims the largest microbiological input portfolio in Latin America with over 25 products, including flagship technologies EficazControl (a biological fungicide developed with EMBRAPA that can replace 100% of chemical fungicides), SolubPhos (a phosphorus solubilizer developed with EMBRAPA), and the VirControl virucide line. Many products are formulated for ambient-temperature storage with shelf lives of 6–36 months, eliminating cold-chain logistics in distribution.

The company serves large-scale and mid-scale Brazilian agricultural producers cultivating soybeans, corn, wheat, cotton, beans, peanuts, sugarcane, and coffee, addressing yield maximization, soil degradation, chemical resistance, and sustainability certification requirements. Its go-to-market combines a network of agricultural distributors and cooperatives across Brazil with direct field sales, technical support via phone and WhatsApp, and event-driven demand generation at major sector events like the ANDAV Congress. International expansion began in March 2025 through a strategic distribution partnership with Corteva Agriscience to bring SolubPhos to over 20 European countries. The company also operates a subsidiary, Simbiose Paraguai, for the Paraguayan market.

Simbiose holds ABNT NBR ISO 9001:2015 and ISO 14001:2015 certifications, has conducted annual GHG inventories since 2021 aligned with ISO 14064 and the GHG Protocol, and achieved Carbon Neutral certification in 2025 and a GHG Protocol Gold Seal in 2026. The company is privately held with no disclosed external investors, ownership structure, or revenue figures.

Name

Simbiose

Legal name

SIMBIOSE-AGRO

Website

https://simbiose-agro.com.br

Company type

Private

Founded year

2007

Operating status

Operating

Headcount range

251–500 employees

Short description

Simbiose Agro is a Brazilian agricultural biotechnology company that develops and produces microbiological inputs — biodefensives, inoculants, fertilizers, and adjuvants — for large-scale row-crop farmers across Brazil, with growing international presence through a Corteva Agriscience distribution partnership in Europe.

Ownership category

akta.pro rank

Product category

Agricultural Biological Inputs (Biodefensives, Inoculants, and Natural Fertilizers)

NAICS

Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (3253), Pesticide and Other Agricultural Chemical Manufacturing (32532), Fertilizer and Compost Manufacturing (32531)

SIC

Agricultural Chemicals (2870)

akta.pro primary industry

Biofertilizers & Microbial Inoculants (IMAEAEAG)

akta.pro secondary industries

Microbial Biofungicides (AFABAEAB), Biological Seed Treatments & Inoculants (within Biologicals) (AFABAEAL), Biological Formulation, Fermentation & Scale-Up Manufacturing (AFABAEAM)

Keywords

• Agricultural biodefensives
• Biological nitrogen fixation
• Microbiological crop protection
• Agricultural inoculants
• Natural agricultural fertilizers

Headquarters

HQ city

Cruz Alta

HQ country

Brazil

HQ region

Latin America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Agricultural biological inputs: Revenue is generated through the sale of biological crop protection products (biodefensives/biofungicides/bionematicides/bioinsecticides), inoculants for biological nitrogen fixation, fertilizers, and adjuvants to agricultural producers across Brazil and internationally. The company sells directly to large-scale farmers through distributors and at agricultural trade events. International expansion began with SolubPhos distribution in Europe via Corteva Agriscience.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Simbiose Agro develops, manufactures, and sells microbiological agricultural inputs based on bacteria, fungi, and viruses for crop protection, biological nitrogen fixation, and soil fertility enhancement. The company operates the largest portfolio of microbiological agricultural inputs in Latin America, spanning biodefensives (biofungicides, bionematicides, bioinsecticides), inoculants, fertilizers, and adjuvants. Products are formulated for seed treatment, foliar, and furrow application and are designed to replace or reduce dependence on chemical pesticides and synthetic fertilizers.

Product overview

Simbiose is a Brazilian agricultural biotech company that develops and produces microbiological inputs for agriculture. The company offers the largest portfolio of microbiological inputs in Latin America, including biodefensives (biological pesticides/fungicides/nematicides), inoculants (nitrogen-fixing bacteria), fertilizers, adjuvants, and additives. The portfolio includes over 25 distinct products across categories: biodefensives such as EficazControl, FrontierControl, NemaControl, StimuControl, GreenControl; inoculants including SimbioseNod (for soybean, peanut, beans, cowpea), SimbioseMaíz (for corn/soybean/wheat); fertilizers like StimuFull and StimuLeg series; and adjuvants such as Bio Pro TSI, Simbose Pro series, and StimuSpray line. Products are based on microorganisms (bacteria, fungi, viruses) and aim to increase soil fertility and nutrient availability while being environmentally sustainable. Notable partnerships include EMBRAPA for product development and Corteva Agriscience for international distribution.

Differentiator

Problem solved

Functional benefit

Brands

• EficazControl: First biological fungicide developed with EMBRAPA
• SolubPhos
• FrontierControl
• NemaControl
• SimbioseNod
• BTControl
• VirControl
• MethaControl
• FlyControl
• GreenControl
• StimuControl
• Bio Pro
• Dupla Proteção
• TSI

Products and services

• EficazControl Biological fungicide developed in partnership with EMBRAPA. Replaces 100% of chemical fungicides with up to 80% efficiency against soil fungi and multiple rot types, for crop protection in Brazilian agriculture.
• FrontierControl Microbiological biofungicide for foliar disease control, marketed as the most complete biofungicide in the market for row crops.
• NemaControl Microbiological nematicide with proprietary strain SIMBI BS 10 (CCT 7600) for high-efficiency control of main nematode species. Liquid formulation, room temperature storage, 36-month shelf life.
• StimuControl Microbiological fungicide for soil-borne disease control. Active ingredient SIMBI T5 (CCT 7589), liquid formulation that does not require refrigeration.
• StimuControl Evolution Microbiological fungicide specifically for White Mold (Sclerotinia sclerotiorum) control. Exclusive SIMBI T5 (CCT7589) strain in OD liquid formulation with room temperature storage.
• GreenControl Powder-form microbiological fungicide for industrial seed treatment (TS). Contains Trichoderma harzianum SIMBI T5 (CCT7589); protects against Fusarium solani and Sclerotinia sclerotiorum (white mold) via competition, antibiosis, and parasitism.
• SolubPhos Phosphorus solubilizer developed in partnership with EMBRAPA. Solubilizes phosphorus retained in soil to make it available to plants, improving nutrient availability without environmental harm. Distributed in Europe via Corteva Agriscience.
• SimbioseNod Ultra TSI High-quality inoculant for biological nitrogen fixation in soybeans for exclusive use in industrial seed treatment (TSI). Contains Bradyrhizobium japonicum (SEMIA 5079 + SEMIA 5080); no refrigeration required; 6-month shelf life.
• SimbioseNod Soja Líquido Liquid inoculant for biological nitrogen fixation in soybean crops. Based on Bradyrhizobium japonicum (SEMIA 5079 and SEMIA 5080); no refrigeration required; up to 6 months shelf life.
• SimbioseNod Soja Turfoso Peat-based inoculant for biological nitrogen fixation in soybean crops. Based on Bradyrhizobium japonicum (SEMIA 5079 and SEMIA 5080).
• SimbioseNod Amendoim Inoculant for biological nitrogen fixation in peanut crops. Based on Bradyrhizobium sp. (SEMIA 6144); 6-month shelf life without refrigeration.
• SimbioseNod Feijão Inoculant for biological nitrogen fixation in bean crops. Based on Rhizobium tropici (SEMIA 4077); no refrigeration required.
• SimbioseNod Feijão Caupi Inoculant for biological nitrogen fixation in cowpea crops. Based on Bradyrhizobium sp. (SEMIA 6462); 6-month shelf life without refrigeration.
• SimbioseMaíz Líquido Liquid inoculant for biological nitrogen fixation in corn, soybean, and wheat crops. Based on Azospirillum brasilense (Ab-V5 and Ab-V6); no refrigeration required; promotes root development and plant growth.
• SimbioseMaíz Turfoso Peat-based inoculant for biological nitrogen fixation in corn, soybean, and wheat crops. Based on Azospirillum brasilense (Ab-V5 and Ab-V6); no refrigeration required.
• BTControl Microbiological insecticide for control of caterpillars including Helicoverpa armigera, Anticarsia gemmatalis, Chrysodeixis includens, and Diaphania hyalinata. Based on Bacillus thuringiensis var. kurstaki, strain HD-1 (CCT 1306); 17,600 IU/mL concentration; 36-month shelf life.
• FlyControl Microbiological insecticide with proprietary active ingredient BB15 for control of sucking pests including Anthonomus grandis, Bemisia tabaci, Dalbulus maidis, Dichelops melacanthus, and Euschistus heros. OD liquid formulation; room temperature storage.
• MethaControl Microbiological insecticide for control of root leafhopper (Mahanarva fimbriolata), pasture leafhopper (Zulia entreriana), and Deois flavopicta. Based on Metarhizium anisopliae, isolate IBCB 425.
• MethaControl Evolution Microbiological insecticide for control of Brown Stink Bug (Scaptocoris castanea). Based on Metarhizium anisopliae; OD liquid formulation with room temperature storage.
• VirControl H.a. First microbiological insecticide developed in Brazil for Helicoverpa armigera control. Developed in partnership with EMBRAPA. Based on Helicoverpa armigera Multiple Nucleopolyhedrovirus; formulation does not require refrigeration; self-perpetuating infection cycle in field.
• VirControl C.i. First microbiological insecticide developed in Brazil for False Looper control (Chrysodeixis includens and Rachiplusia nu). Developed in partnership with EMBRAPA; formulation does not require refrigeration.
• Bio Pro TSI Polymer-based additive for industrial seed treatment (TSI) that improves adherence and survival of bacteria on seeds. Allows planting up to 60 days after treatment; 30-month shelf life.
• Simbiose Pro Additive for seed treatment that improves adherence and survival of bacteria for biological nitrogen fixation. Allows planting up to 5 days after treatment; 30-month shelf life.
• Simbiose Pro Super Additive for seed treatment that improves adherence and survival of all microorganisms. Allows planting up to 10 days after treatment; 30-month shelf life.
• StimuFull Fertilizer with macro and micronutrients (N 10%, P 5%, K 8%, Ca 1%, Mg 0.6%, Mo 0.1%, Bo 0.5%, Cu 0.1%, Fe 0.1%, Mn 0.3%, Zn 0.7%). 36-month shelf life; formulated for foliar application.
• StimuLeg 15 Fertilizer with Molybdenum (Mo 15%) and Nickel (Ni 1%) essential for biological nitrogen fixation (BNF) processes. 36-month shelf life.
• StimuSpray D Agricultural adjuvant for herbicide application. Provides pH regulation, better coverage, and significant drift reduction. Dosage: 30-50 mL per 100 L water.
• StimuSpray F Agricultural adjuvant for fungicide and insecticide spray application. Provides pH regulation, better coverage, and homogenization. Dosage: 30-50 mL per 100 L water.
• StimuSpray O Spreading adhesive agricultural adjuvant for better coverage, penetration, and wetting. Reduces surface tension for better nutrient circulation.

Quantifiable outcome

• Up to 80% efficiency in controlling soil fungi
• +4 more outcomes

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature9 records

Partnerships

One partnership is on record.

• Corteva AgriscienceflagshipChannel Partner/ Reseller/ Distributor · 1 March 2025Simbiose entered a strategic partnership with Corteva Agriscience to distribute its SolubPhos phosphorus solubilizer technology in over 20 European countries. This is the first Brazilian agricultural biosolution to enter the European market, representing Simbiose's inaugural international expansion. The partnership positions Corteva as the exclusive or primary distributor for this product line in Europe and potentially the USA.

Scale indicators8 records

Recent moves6 records

Expansion highlights7 records

Emerging players

• Indigo Ag: US-based ag-tech company offering microbial seed treatments and biological inputs for major row crops. Comparable in developing microbial-based agricultural solutions for large-scale row crop farmers, though with broader digital agriculture and sustainability marketplace components.
• BioConsortia: US-based agricultural biotech using advanced microbial selection and discovery to develop nitrogen-fixing, phosphorus-solubilizing, and biocontrol products. Comparable technology approach (proprietary microbial strain libraries) and product categories, though focused primarily on US and select international markets.

Direct peers

• Novonesis (formerly Novozymes BioAg): Global leader in microbial agricultural inputs including bio fungicides, bioinsecticides, and inoculants. Closely comparable to Simbiose in product categories (biodefensives and biofertilizers), target market (row crop producers), and business model (proprietary strain libraries, formulation, and global distribution).
• Symborg (Corteva subsidiary): Spanish agricultural biotech specializing in biostimulants and biocontrol, now owned by Corteva Agriscience. Direct competitor to Simbiose in microbial agricultural inputs and now part of Corteva, which is Simbiose's European distribution partner, creating an interesting competitive/channel dynamic.
• Pivot Bio: US-based agricultural biotechnology company specializing in microbial nitrogen fixation for corn and other crops. Directly comparable to Simbiose's SimbioseNod and SimbioseMaíz inoculant lines, with similar microbial-based approach to replacing synthetic nitrogen fertilizer.
• Biotrop Soluções Biológicas: Brazilian agricultural biological inputs company offering bioinsecticides, bionematicides, biofungicides, and inoculants to Brazilian row crop producers. Direct competitor in the same Brazilian market with overlapping product categories, customer base, and distribution channels.
• Lallemand Plant Care: Canadian-based specialty yeast and bacteria producer with a dedicated Plant Care division offering biofertilizers, biostimulants, and biocontrol products globally. Comparable to Simbiose in microbial formulation expertise and agricultural applications across multiple crop segments.
• Bioceres Crop Solutions: Latin American agricultural biotechnology company (Argentine-based) offering biological inputs including inoculants, biofertilizers, and biocontrol products. Comparable geographic focus on South American row crops and similar product portfolio targeting soybean and corn producers.

Broad incumbents

• Corteva Agriscience: Global agricultural inputs major offering seeds, crop protection chemicals, and digital services, with growing biologicals portfolio. Comparable as both a partner (European distribution of SolubPhos) and competitor across multiple biological input categories, with vastly superior global scale and distribution.
• Bayer Crop Science: Global agricultural input giant offering seeds, crop protection, and digital tools, with an expanding biologicals portfolio through acquisitions (e.g., AgraQuest). Comparable as competitor across biodefensives and inoculants, with global distribution and significantly larger R&D resources.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/simbioseagro

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Simbiose