I.S.E.
- Company typePrivate
- Founded1992
- HeadquartersGuidonia, Italy
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What I.S.E. does
I.S.E. S.r.l. is an Italian in-vitro diagnostics (IVD) manufacturer founded in 1992 and headquartered in Guidonia Montecelio (Rome), Italy, with a secondary R&D and production site in Rome. The company designs, develops, and produces fully automated clinical chemistry analyzers and a complete CE-marked reagent and consumable panel, with all manufacturing performed in Italy. Its product portfolio spans four analyzers (HEMO ONE, MIURA ONE, MIURA 200, and the flagship MIURA) covering throughputs from 60 to 500 tests/hour, an integrated ISE module for electrolyte analysis (Na+, K+, Li+, Cl-), and reagent lines for clinical chemistry, turbidimetry, HbA1c, plasma proteins, and stool testing. The instruments run Windows-based software, support barcode-driven sample/reagent identification, capacitive liquid level detection, and bidirectional LIS integration via Ethernet/TCP-IP under ASTM E1381-02 and NCCLS LISA2 standards.
The business model follows a classic IVD razor-and-blade structure: hardware analyzer sales carry a 2-year warranty and are complemented by recurring revenue from validated reagents (mono and bi-reagent kits ranging from roughly 100 to 1,369 tests per kit), calibrators and controls, ISE electrode and reagent pack replacement, and consumables such as disposable cuvettes, cleaning and rinse solutions, sample cups, and pump heads. Pricing is quote-based and not publicly disclosed. Go-to-market is a global distributor-led enterprise field sales motion supplemented by direct website engagement, an account/registration system, social channels (Facebook, LinkedIn, YouTube), trade show participation (MEDLAB Dubai 2026, WHX Labs Dubai 2027), and downloadable technical documentation. The company also maintains a group-company relationship with Adaltis, an IVD peer in molecular diagnostics and microELISA, enabling joint exhibition presence.
I.S.E. is a privately held Italian S.r.l. with 11-50 employees, ISO 9001:2015 and ISO 13485:2016 certifications from TÜV Italia Srl, and claims thousands of analyzers installed worldwide. The company targets hospital laboratories, small-to-mid-sized independent labs, physician offices and clinics, and veterinary laboratories, with no disclosed revenue, funding history, named end customers, or senior leadership team in the public record.
I.S.E. firmographics
Firmographics- Name
- I.S.E.
- Legal name
- I.S.E. S.r.l.
- Website
- https://logotech-ise.com
- Company type
- Private
- Founded year
- 1992
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Ownership category
- akta.pro rank
I.S.E. industry classification
Industry- Product category
- In-Vitro Diagnostics (IVD) Clinical Chemistry Analyzers
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), In-Vitro Diagnostic Substance Manufacturing (325413)
- SIC
- Laboratory Analytical Instruments (3826), In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Clinical Chemistry & Hematology Diagnostics (automated analyzers, blood testing) (HLAAALAH)
- akta.pro secondary industries
- Laboratory Automation, Sample Prep & Liquid Handling (IVD Lab Diagnostics) (HLAHAAAN), IVD Reagents, Assay Kits & Consumables (Non-instrument) (HLAHAAAM)
Keywords
Where I.S.E. is headquartered
LocationHeadquarters
- HQ city
- Guidonia
- HQ country
- Italy
- HQ region
- Europe
Offices2 records
Markets served
I.S.E. business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Others
Revenue model
- Clinical Chemistry Analyzers: Sale of automated clinical chemistry analyzers (HEMO ONE, MIURA ONE, MIURA 200, MIURA) to laboratories. Hardware sales with 2-year warranty included.
- Diagnostic Reagents and Test Kits: Recurring sales of CE-marked stable liquid reagents (mono and bi-reagent) for clinical chemistry, turbidimetry, and latex tests. Sold in kits with varying tests per kit (e.g., 100-1369 tests depending on parameter).
- Disposables and Consumables: Ongoing sales of consumables including systemic solutions, cleaner solutions, rinse solutions, reading cuvettes, sample cups, reagent bottles, halogen lamps, pump heads, and sampling probes for Miura and HEMO ONE systems.
- ISE Module Components: Sales of ISE module components including electrodes (Na, K, Cl, Li, Reference, Spacer), reagent packs, urine diluent, and cleaning solutions for Miura analyzer systems.
- Calibrators and Controls: Sales of quality control materials including multi-calibrator, normal/pathological control serum, and dedicated calibrators/controls for specific assays like HbA1c, Vitamin D, CRP, and lipids.
Go-to-market motion1 record
Distribution channels3 records
Marketing channels6 records
I.S.E. product offering
Product offeringCore offering
I.S.E. S.r.l. designs, manufactures, and distributes fully automated clinical chemistry analyzers (HEMO ONE, MIURA ONE, MIURA 200, MIURA) with integrated ISE modules for electrolyte analysis, together with a complete CE-marked stable liquid reagent panel, calibrators, controls, and disposable consumables. The portfolio targets hospital laboratories, independent labs, doctor offices, clinics, and veterinary facilities globally.
Product overview
I.S.E. Srl is an Italian IVD company that develops and manufactures a comprehensive portfolio of fully automated clinical chemistry analysers for the global in-vitro diagnostics market. The product line includes the HEMO ONE (compact, versatile analyser for small-to-mid-sized labs), the MIURA family (comprising MIURA ONE, MIURA 200, and MIURA flagship models offering increasing throughput from 180 to 500 tests/hour), and an ISE Module for electrolyte analysis. The company complements its instrumentation with a complete CE-marked reagent panel including clinical chemistry parameters, turbidimetry assays, and stool testing kits (Haemoglobin FOB, Calprotectin, Pancreatic Elastase), along with dedicated calibrators, controls, and consumables. I.S.E. serves hospital laboratories, healthcare professionals, independent labs, and veterinary facilities with solutions adapted to any laboratory size.
Differentiator
Problem solved
Functional benefit
Brands
- Miura Family: A range of fully automated clinical chemistry analysers including Miura, Miura 200, and Miura One, designed for various laboratory sizes from small to mid-sized.
- HEMO ONE
Products and services
- HEMO ONE Clinical Chemistry Analyzer
Quantifiable outcome
- Up to 500 tests/hour with ISE module integration
- +2 more outcomes
Companies that use I.S.E.
Customer profileSegments5 records
Ideal customer profiles4 records
I.S.E. technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration1 record
Feature7 records
I.S.E. partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- AdaltiscoreAdaltis is the parent/group company of I.S.E. Srl. Adaltis develops, manufactures, and markets in-vitro diagnostic systems and reagents, including molecular diagnostic instruments (EXTRAlab, AMPLilab), microELISA analyzers, and ELISA reagent kits (EIAgen). Products include nucleic acid extraction and PCR systems for infectious disease and genomic testing.
Scale indicators3 records
Recent moves5 records
Expansion highlights5 records
I.S.E. competitors and assessment
Company assessmentOthers
- Adaltis: Group company of ISE selling molecular diagnostic and microELISA instruments and reagents. Not a direct competitor to ISE's clinical chemistry line but a closely related IVD peer within the same corporate group.
Emerging players
- Agappe Diagnostics: Smaller emerging-market clinical chemistry and immunoassay analyzer maker with reagent bundles; partial overlap with ISE in price-sensitive geographies and small-to-mid lab segment.
Direct peers
- Erba Mannheim: Mid-tier clinical chemistry and immunoassay analyzer maker focused on cost-effective solutions for small-to-mid labs in emerging markets — a direct head-to-head peer for ISE's HEMO ONE and MIURA positioning.
- ELITechGroup: European IVD manufacturer offering clinical chemistry analyzers, reagents, and dedicated consumables. Closely matches ISE on integrated instrument-plus-reagent bundles and on a European manufacturing/distribution footprint.
- Horiba Medical: Mid-sized clinical chemistry and hematology analyzer manufacturer with a strong global distributor model, most comparable to ISE in target customers (hospital and independent labs) and product positioning (compact-to-mid-throughput random access analyzers).
- Dirui Industrial: Chinese clinical chemistry and urinalysis analyzer manufacturer with a strong footprint in emerging markets and a portfolio of compact-to-mid-throughput analyzers, directly comparable to the MIURA family.
Broad incumbents
- Roche Diagnostics: Global IVD market leader with cobas clinical chemistry analyzers and integrated ISE. ISE's primary competitive reference point, particularly for mid-sized hospital labs that may evaluate both vendors.
- Mindray: Large Chinese IVD incumbent with a full clinical chemistry, hematology, and immunoassay analyzer portfolio. Competes with ISE in emerging markets and increasingly in Europe on price-performance, but at meaningfully larger scale.
- Siemens Healthineers: Atellica and Advia clinical chemistry lines compete across the throughput range ISE covers; defines the upper bound of competitive intensity ISE faces in mid-sized hospital accounts.
- Randox: Established IVD manufacturer with a broad clinical chemistry and immunoassay reagent menu and analyzer hardware; overlaps ISE on the reagent-and-instrument bundle model in mid-tier lab segments.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat4 records
Key risks5 records
Key highlights6 records
Customer concentration
I.S.E. social profiles
Digital presenceI.S.E. compliance and trust
Trust signalCompliance3 records
I.S.E. financial estimates
Financial estimateRevenue estimate
Valuation estimate
I.S.E. leadership team
Management profileNumber of profiles
I.S.E. funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
I.S.E. M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about I.S.E.
What does I.S.E. do?
I.S.E. S.r.l. designs, manufactures, and distributes fully automated clinical chemistry analyzers (HEMO ONE, MIURA ONE, MIURA 200, MIURA) with integrated ISE modules for electrolyte analysis, together with a complete CE-marked stable liquid reagent panel, calibrators, controls, and disposable consumables. The portfolio targets hospital laboratories, independent labs, doctor offices, clinics, and veterinary facilities globally.
Is I.S.E. a public or private company?
I.S.E. is a private company. It is classified as corporate owned and is currently operating.
When was I.S.E. founded?
I.S.E. was founded in 1992. It employs 11 to 50 people.
Where is I.S.E. based?
I.S.E. is headquartered in Guidonia, Italy, in the Europe region.
How does I.S.E. make money?
Five revenue lines are on record. Clinical Chemistry Analyzers are the primary driver. The others are diagnostic Reagents and Test Kits, disposables and Consumables, ISE Module Components and calibrators and Controls.
Who are I.S.E.'s main competitors?
Adaltis is listed as an others. Agappe Diagnostics is listed as an emerging player. Direct peers are Erba Mannheim, ELITechGroup, Horiba Medical and Dirui Industrial. Broad incumbents are Roche Diagnostics, Mindray, Siemens Healthineers and Randox.
Does I.S.E. have an API?
No public API is recorded for I.S.E..
What industry is I.S.E. in?
I.S.E.'s product category is In-Vitro Diagnostics (IVD) Clinical Chemistry Analyzers. Its primary akta.pro industry code is HLAAALAH, Clinical Chemistry & Hematology Diagnostics (automated analyzers, blood testing), with a secondary code of HLAHAAAN, Laboratory Automation, Sample Prep & Liquid Handling (IVD Lab Diagnostics). Its NAICS code is 334516 and its SIC code is 3826.