Health Care Systems

What Health Care Systems does

Healthcare Systems Co., Ltd. (株式会社ヘルスケアシステムズ) is a Nagoya-based, privately held Japanese biotechnology and mail-in diagnostic testing company founded in 2009 as a Nagoya University-affiliated venture. Its core business is a portfolio of more than 20 mail-in biomarker test kits (郵送検査) covering equol production (Soy Check), sodium/potassium ratio (Salt Check), intestinal environment, oral immune function, oxidative stress, protein intake, dust mite allergens, infant skin barrier (Baby Well Check, with Kao), and colorectal cancer risk (Collastin Test), all built on an in-house analytical stack spanning ELISA, HPLC, GC, LC/MS, RT-PCR, and NGS. The company earns revenue across four service lines: direct-to-consumer kit sales through the karadacheck.com e-commerce platform, B2B contract laboratory analysis for food/pharma clients, clinical trial design and execution for corporations and municipalities, and health-promotion services for corporate wellness programs. Its commercial moat rests on a Japan-wide distribution network of more than 1,000 medical institutions, 4,000+ pharmacies/drugstores, and 80+ corporate and 20+ insurance/municipal accounts, augmented by ISO/IEC 27001 and ISO/IEC 17025 certifications secured in 2024. Healthcare Systems owns three subsidiaries (Dante, Adenoprevent, and Shanghai Reken Seibutsu Technology in China) and pursues an explicit DX strategy to convert raw test results into AI-assisted personalized health action recommendations, anchored by a proprietary OCTA ERP-based core system.

Name

Health Care Systems

Legal name

株式会社ヘルスケアシステムズ

Website

https://hc-sys.com

Company type

Private

Founded year

2009

Operating status

Operating

Headcount range

51–100 employees

Short description

Healthcare Systems is a Nagoya-headquartered Japanese biotech that develops and sells more than 20 mail-in biomarker diagnostic test kits (equol, salt intake, gut health, skin barrier, cancer risk) directly to consumers and runs B2B contract lab analysis, clinical research, and corporate health-promotion services for municipalities, health insurers, and consumer-goods companies across Japan.

Ownership category

akta.pro rank

Product category

Mail-in Diagnostic & Lifestyle Biomarker Testing

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Medical Laboratories (621511)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Services-Medical Laboratories (8071), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Remote Diagnostics & Home Testing Devices (Connected POC/At-Home Diagnostic Readers) (HLAHACAL)

akta.pro secondary industries

Remote Diagnostics & Point-of-Care (Connected Testing, Home Lab Devices) (HLACAPAK), Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB), Clinical Biomarker Testing Services (central labs, trial enrollment/monitoring assays) (HLAAAMAC), Personal Medical Devices & Home Diagnostics (Thermometers, Blood Pressure Monitors, Glucose Meters, Rapid Tests) (CRADAMAK)

Keywords

• Mail-in diagnostic testing
• Biomarker analysis services
• Preventive health screening
• Clinical research services
• Contract laboratory testing

Headquarters

HQ city

Nagoya

HQ country

Japan

HQ region

Asia

Offices3 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure, Supply Chain

Revenue model

1. Mail-in Test Kit Sales (郵送検査事業): Direct sales of consumer mail-in test kits for measuring various health biomarkers (equol, salt intake, gut environment, skin barrier, etc.). Customers purchase kits online, collect samples at home, and receive analysis results digitally.
2. Contract Testing Services (受託検査事業): B2B laboratory services for companies, research institutions, and local governments requiring biomarker analysis. Includes analysis of biological samples (blood, urine, saliva, tears) and food samples, biomarker discovery, and functional food R&D support.
3. Clinical Research Services (臨床研究事業): Clinical trial design, execution, and PR support services for companies and municipalities. From pilot studies to large-scale trials involving hundreds of participants. Includes ethical review committee coordination and academic presentation support.
4. Health Promotion Services (健康支援事業): Services supporting corporate and municipal health literacy initiatives, including health check-up events, nutrition education seminars, and educational programs for families and youth.

Pricing tiers

Go-to-market motion3 records

Distribution channels5 records

Marketing channels5 records

Core offering

Healthcare Systems develops and sells a portfolio of mail-in diagnostic test kits that let individuals measure lifestyle-related biomarkers (equol production, salt intake, gut environment, oxidative stress, immune function, infant skin barrier, colorectal cancer risk, and more) by collecting urine, saliva, sebum, or stool samples at home and receiving digital results. The company also provides contract laboratory analysis services for biological and food samples using ELISA, HPLC, GC, LC/MS, and RT-PCR methods, conducts clinical research and trial operations for corporations and municipalities, and runs corporate and community health literacy programs.

Product overview

Healthcare Systems operates as a mail-in testing services company (郵送検査事業) with a portfolio of over 20 test kit products for health monitoring and disease prevention. The core products include the Soy Check (ソイチェック) for equol testing, Baby Well Check (ベビウェルチェック) for infant skin barrier assessment using sebum RNA technology, and various mail-in tests including salt intake (シオチェック), gut health (肠活チェック), immune function (バリアチェック), oxidative stress (サビチェック), dust mite allergens, and more. The company also provides contract testing services (受託検査事業) using ELISA, HPLC, GC, LC/MS, and real-time PCR, and clinical research services (臨床研究事業) from pilot studies to large-scale trials. Business divisions are supported by the proprietary OCTA system built on ERP5 for integrated data management. The company positions itself in the pre-symptomatic health management (未病) market with a DX strategy to evolve from presenting test numbers to recommending personalized health actions.

Differentiator

Problem solved

Functional benefit

Brands

• カラダのものさし (Karada no Monosashi): Consumer-facing mail-in testing service brand offering various health checkup kits including soy check, salt check, and other wellness tests.

Products and services

• Soy Check (エクオール検査「ソイチェック」) Mail-in urine test kit that determines whether an individual can produce equol from soy isoflavones, measuring equol-producing ability in 5 levels and supporting personalized soy and supplement intake recommendations. Used by individual consumers for self-care and by corporate wellness programs (e.g., Yahoo Japan, Marubeni) for menopause and women's health initiatives.
• Baby Well Check (肌バリア検査「ベビウェルチェック」) Mail-in sebum RNA test for infants that assesses skin barrier function from sebum RNA information and provides personalized skin care recommendations. Developed jointly with Kao using sebum RNA monitoring technology. Used by parents and municipal infant care programs (e.g., Seki City in partnership with Kao), with reported outcomes of 97% of parents maintaining good skincare habits.
• Salt Check / Salt Check Plus (減塩検査「シオチェック」/「シオチェック+（プラス）」) Mail-in urine test that measures sodium-to-potassium ratio (ナトカリ比) to assess salt intake and dietary balance. Used for hypertension prevention and dietary guidance programs, including Tsurugashima City's 40s-50s dietary improvement project.
• Intestinal Activity Check (腸活チェック) Mail-in urine test measuring intestinal decay substances (indican in urine, 尿中インドキシル硫酸) to assess gut environment health and recommend dietary improvements. Used in Asahi Group Foods' Dear Natura campaign and Morinaga Milk Industry's gut health yogurt campaigns.
• Barrier Check (バリアチェック) Saliva IgA antibody mail-in test measuring oral immune function for immune health assessment.
• Protein Check (フレミーチェック) Mail-in urine test measuring protein intake levels and deficiency to assess nutritional status and support frailty (フレイル) prevention programs.
• Oxidative Stress Check (サビチェック) Mail-in urine test measuring oxidative stress markers (8-OHdG) to assess cellular 'rust' levels and antioxidant needs.
• Dust Mite Allergen Test (ダニアレルゲン検査) Mail-in test for quantifying dust mite allergen levels in bedroom floors and bedding. Used for allergy prevention and environmental assessment; referenced in research studies on the impact of air-conditioning systems on indoor dust mite allergen levels.
• Collastin Test (コリバクチン検査) Mail-in test for colorectal cancer risk assessment. Developed by group company Adeno Prevent (アデノプリベント), measuring collastin levels. Launched as a mail-in testing service for colorectal cancer risk screening.
• Sebum RNA Comprehensive Analysis (皮脂RNA網羅解析) Comprehensive sebum RNA analysis service using Kao's sebum RNA monitoring technology. Non-invasive testing via oil-absorbing film with next-generation sequencing (NGS) analysis covering approximately 10,000 types of sebum RNA expression. Targeted at research institutions for dermatology, health science, and medical research applications. First-time entrusted analysis service by Healthcare Systems.
• Intestinal Bacteria Antibody Test (腸内細菌抗体検査) New antibody-based test for detecting specific gut bacteria using proprietary technology developed with the National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN). Lower cost and faster turnaround than traditional genomic analysis. Provided free to up to 40,000 visitors at Osaka-Kansai Expo 2025 Osaka Healthcare Pavilion.
• Contract Testing Services (受託検査事業) Contract analysis services for biological samples (blood, urine, saliva, tears) and food samples using ELISA, HPLC, GC, LC/MS, and real-time PCR methods. Includes new biomarker development and functional food R&D support. Serves companies, research institutions, and local governments.
• Clinical Research Services (臨床研究事業) Clinical trial services from pilot studies to large-scale trials (hundreds of subjects), including trial design, ethics committee applications, UMIN registration, subject recruitment, trial operations, and PR support. Conducted in collaboration with companies and municipalities; supported by group-company collaboration with Adeno Prevent (AdenoPrevent).
• Health Support Services (健康支援事業) Health literacy promotion activities including test utilization for corporate 健康経営 (health management) programs, health events at commercial facilities, and dietary education seminars for families and youth. Supports corporate, municipal, and community health initiatives.

Quantifiable outcome

• Cumulative mail-in test count reached 1 million+ as of April 2025
• +4 more outcomes

Named customers14 records

Segments5 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability5 records

Feature6 records

Scale indicators8 records

Recent moves7 records

Expansion highlights6 records

Market position

Competitive moat5 records

Key highlights7 records

Customer concentration

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Health Care Systems