Cocalico Biologicals

What Cocalico Biologicals does

Cocalico Biologicals, Inc. is a privately held, woman-owned contract biotechnology service company founded in 1984 and headquartered on approximately 60 acres of farmland in Denver, Lancaster County, Pennsylvania. The company's primary business is custom production of polyclonal and monoclonal antibodies using a standardized 91-day immunization protocol across eleven host species (mice, rats, guinea pigs, chickens, rabbits, goats, sheep, bovine, donkeys, alpacas, and horses), yielding serum volumes from approximately 0.5ml to 900ml per animal. Cocalico also sells a catalog of biological products including filtered and non-filtered animal sera, specialty sera, charcoal-treated and delipidated sera, plasmas, red blood cells, and related biological materials such as tissues, glands, and reticulocyte-rich blood.

The company operates USDA-inspected laboratory animal facilities under multiple regulatory certifications (USDA Dealers License 23-B-0028, USDA Research License 23-R-0088, NIH Animal Welfare Assurance D16-00398, and FDA Blood Establishment ID 3039674384). Its go-to-market is sales-led and direct: customers submit antigens along with project and non-duplication assurance forms, and finished antisera are shipped frozen on dry ice via priority overnight delivery. Pricing is unit-based per animal, ranging from $224.50 (mouse) to $1,521.80 (goat), with additional fees for ELISA evaluation ($65/bleed), antigen conjugation, and specialty services. Over its 40-year history, Cocalico has grown exclusively through word-of-mouth referrals rather than formal sales or marketing investment, and serves a horizontal customer base of academic, government, and commercial research laboratories across the United States.

Name

Cocalico Biologicals

Legal name

Cocalico Biologicals, Inc.

Website

https://cocalicobiologicals.com

Company type

Private

Founded year

1984

Operating status

Operating

Headcount range

11–50 employees

Short description

Cocalico Biologicals is a woman-owned, privately held biotech contract service founded in 1984 that produces custom polyclonal and monoclonal antibodies across 11 host species and sells related biological products (sera, plasmas, red blood cells) to US research institutions and academic and commercial laboratories.

Ownership category

akta.pro rank

Product category

Custom Antibody Production Services

NAICS

Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Biological Products, (No Disgnostic Substances) (2836)

akta.pro industry

PRIMARYHLAMAEAK

Biologics & Immunotherapies (Non-vaccine)

Healthcare & Life Sciences/Veterinary & Animal Health/Veterinary Pharmaceuticals & Biologics

SECONDARYAFAEANAK

Veterinary Pharmacy, Vaccine & Biologics Services

Agriculture & Food Production/Animal Production & Aquaculture/Animal Health & Veterinary Services

SECONDARYAFANAJAC

Blood Processing (Edible Blood Products, Plasma for Food Use)

Agriculture & Food Production/Meat, Poultry & Seafood Processing/Co-Product & Specialty Processing (Offal, Organ Meats, Specialty Cuts)

Keywords

• Custom antibody production
• Polyclonal antibody services
• Monoclonal antibody services
• Biological reagent supply
• Animal sera products

Headquarters

HQ city

Reamstown

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Supply Chain

Revenue model

1. Custom Antibody Production Services: One-time service fees for custom antibody production in various host species. Pricing varies by species (mouse $224.50, rat $255.00, guinea pig $253.60, chicken $327.75, rabbit $439.96, goat $1,521.80, sheep $1,293.00). Includes host species cost, daily care and maintenance for 91 days, pre-bleed, inoculations, test bleeds, production bleeds, and disposal charge. Additional services include ELISA testing ($65.00/bleed) and antigen conjugation.
2. Biological Products Sales: Sale of biological products including normal animal sera (filtered/non-filtered), specialty sera, charcoal treated sera, delipidated sera, plasmas, related biological products (tissues, glands, organs, reticulocyte rich blood, reticulocyte lysate), and animal whole blood products (red blood cells).

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels1 record

Core offering

Cocalico Biologicals produces custom polyclonal and monoclonal antibodies in a wide range of host species (mice, rats, guinea pigs, chickens, rabbits, goats, sheep, bovine, donkeys, alpacas, horses) following a standard 91-day immunization protocol or investigator-supplied protocols. The company also supplies catalog and specialty biological products including filtered and non-filtered sera, specialty sera, charcoal-treated sera, delipidated sera, plasmas, animal whole blood products (red blood cells), and related biological products such as tissues, glands, organs, reticulocyte-rich blood, and reticulocyte lysate.

Product overview

Cocalico Biologicals offers two core product lines: Custom Antibody Production services (polyclonal and monoclonal antibodies produced in various host species with standardized or custom protocols) and Biological Products (catalog and specialty biological products including various sera, plasmas, and animal blood products). The company operates as a biological manufacturing organization rather than a software platform, providing laboratory services with no unified software product or modular architecture.

Differentiator

Problem solved

Functional benefit

Products and services

• Custom Antibody Production
• Biological Products Supply
• Antigen Conjugation Service

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Scale indicators4 records

Recent moves3 records

Expansion highlights3 records

Broad incumbents

• Bio-Rad Laboratories: Major life sciences instrumentation and reagent company offering custom polyclonal antibody services, animal sera, and blood-derived reagents alongside a broad clinical and research product portfolio.
• Cell Signaling Technology: Large commercial antibody manufacturer producing validated monoclonal and polyclonal antibodies for research applications; broader catalog but overlapping host species and use case (Western blot, IHC, IP).
• Abcam: Large antibody catalog company serving research customers with thousands of off-the-shelf products; competes for antibody research budgets and increasingly offers rabbit monoclonal custom services.
• Thermo Fisher Scientific (Invitrogen Custom Antibody Services): Global life sciences leader offering custom antibody production, sera, plasma, and blood-derived research reagents as part of a much broader bioscience portfolio; provides direct competitive pressure through scale and bundled services.

Direct peers

• ProSci Incorporated: Custom polyclonal and monoclonal antibody production service provider serving academic and biotech researchers with similar host species menus and assay validation services.
• Rockland Immunochemicals: Pennsylvania-based custom antibody and immunoassay service provider producing polyclonal and monoclonal antibodies in rabbits, goats, chickens, and other species; extremely close geographic and product overlap with Cocalico Biologicals.
• GenScript: Global contract service provider offering custom polyclonal and monoclonal antibody production across multiple host species alongside gene synthesis and biologics services; directly comparable to Cocalico's core custom antibody offering for research customers.
• Lampire Biological Laboratories: Pennsylvania-based contract manufacturer of polyclonal antibodies, animal-derived blood products (plasma, serum, red blood cells), and specialty biological reagents; directly comparable product mix including sera, plasma, and whole blood products.

Regional players

• Y Charpente: Note: covance.com redirects to Labcorp Drug Development; CRO offering large-scale custom antibody and biological reagent production services for clinical and research use, similar but with broader scale and contract research organization capabilities.

Emerging players

• SDIX/Novus Biologicals (Bio-Techne): Custom polyclonal antibody and immunoassay developer integrated within Bio-Techne's research reagent platform; comparable host species menu and antigen handling services for research customers.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/cocalico-biologicals-inc

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Cocalico Biologicals