Simple Origin
Simple Origin designs and manufactures cryogenic and in-situ TEM specimen holders, and is the exclusive North American distributor for TVIPS TEM cameras and Bestron in-situ holders, serving life sciences, materials science, and semiconductor researchers globally through direct sales and a regional partner network.
- Company typePrivate
- Founded-
- HeadquartersPittsburgh, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Simple Origin does
Simple Origin Inc. is a privately held, Pittsburgh-based scientific instrumentation company founded circa 2015 by Dr. Pushkarraj Deshmukh. It designs and manufactures cryogenic and in-situ specimen holders for transmission electron microscopy (TEM), with a portfolio spanning cryo transfer holders, cryogenic inert gas/vacuum transfer holders, cryogenic heating/biasing holders, pumping assemblies, and inert gas/vacuum workstations. The company also serves as the exclusive North American representative for TVIPS (TemCam CMOS cameras and imaging software) and Bestron Science and Technology (the INSTEMS series of multi-environment in-situ TEM holders), and integrates NORCADA MEMS chip technology for temperature-controlled cryo experiments.
The business model is hardware sales of high-ASP scientific instrumentation sold on a quote basis, typically under multi-year contracts, to three primary verticals: life sciences research (cryo-EM structural biology), materials science research (battery, nanomaterials, beam-sensitive samples), and semiconductor research (device failure analysis, in-situ biasing). Distribution combines direct enterprise sales from the Pittsburgh headquarters for North America with an exclusive regional partner network covering Japan, EU, France, Canada, China, and India, reaching customers in more than 20 countries.
The company is bootstrapped and founder-led, with a small team of fewer than 50 employees including co-founder Jake Schade (Production Manager) and advisors Hans Tietz (TVIPS founder), Dr. Matthias Stumpf, and Dr. Shinji Aramaki. Notable technical differentiators include an axis-symmetric dewar design for stability at high tilt angles, over 10 hours of liquid nitrogen holding time, transfer temperatures below -175°C, steady-state drift below 3 nm/min with sub-2Å resolution, and MEMS-based multi-environment systems (INSTEMS-MET) with ≤0.1nm spatial resolution and heating rates exceeding 10,000°C/s.
Simple Origin firmographics
Firmographics- Name
- Simple Origin
- Legal name
- Simple Origin Inc.
- Website
- https://simpleorigin.us
- Company type
- Private
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Simple Origin designs and manufactures cryogenic and in-situ TEM specimen holders, and is the exclusive North American distributor for TVIPS TEM cameras and Bestron in-situ holders, serving life sciences, materials science, and semiconductor researchers globally through direct sales and a regional partner network.
- Ownership category
- akta.pro rank
Simple Origin industry classification
Industry- Product category
- Electron Microscopy Instrumentation
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), Other Measuring and Controlling Device Manufacturing (334519)
- SIC
- Laboratory Analytical Instruments (3826), Industrial Instruments For Measurement, Display, And Control (3823)
- akta.pro primary industry
- Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats) (HLAGAIAJ)
- akta.pro secondary industry
- Cryogenic Logistics (LN2 Dry Shippers, -150°C) (HLAGAMAB)
Keywords
Where Simple Origin is headquartered
LocationHeadquarters
- HQ city
- Pittsburgh
- HQ country
- United States
- HQ region
- North America
Offices7 records
Markets served
Simple Origin business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Supply Chain, Operations, Technology or R&D, Marketing or Sales
Revenue model
- Cryogenic TEM Holders: Sale of cryogenic transfer holders, inert gas/vacuum transfer holders, and variable-temperature holders. Multiple models for different TEM manufacturers (Thermo Fisher, JEOL, Hitachi).
- In-situ TEM Holders: Bestron INSTEMS series multi-environment holders for straining, heating, electrical biasing, and tomography applications.
- TVIPS TEM Cameras: Exclusive North American distribution of TVIPS TemCam CMOS camera systems including XF416, XF216, and XF416R models with associated imaging software.
- Accessories and Pumping Assemblies: Pumping chamber solutions for holder storage, warmup, and regeneration. Inert gas/vacuum workstations for controlled sample loading.
- NORCADA MEMS Integration: Cryogenic heating/biasing holders with NORCADA MEMS chip technology including temperature control software and hardware.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Custom quotation-based pricing |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels3 records
Simple Origin product offering
Product offeringCore offering
Simple Origin manufactures and distributes cryo-EM and TEM instrumentation for scientific research, including cryogenic transfer holders, inert gas/vacuum transfer holders, cryogenic heating/biasing holders, pumping assemblies, and inert gas workstations. The company also serves as the exclusive North American distributor for TVIPS TemCam CMOS camera systems and imaging software, as well as the Bestron INSTEMS series of multi-environment in-situ TEM holders. Products are designed for compatibility with Thermo Fisher (FEI), JEOL, and Hitachi TEM systems and target contamination-controlled cryo-EM, in-situ materials characterization, and semiconductor research workflows.
Product overview
Simple Origin offers precision cryo-EM and TEM instrumentation as a unified portfolio of cryogenic transfer holders, in-situ holders, and high-performance camera systems. The product line centers on Cryo Transfer Holders and Cryogenic Inert Gas/Vacuum Transfer Holders for contamination-free sample handling, complemented by the Cryogenic Heating/Biasing Holder for combined thermal-electrical cryogenic experiments. Supporting infrastructure includes Cryo Holders Pumping Assemblies and Inert Gas/Vacuum Workstations. As exclusive North American representative, Simple Origin distributes TVIPS TemCam cameras (XF416, XF216, XF416R) and the TVIPS Digital Imaging Software Suite (EM-MENU, EM-SPECTRO, EM-TOOLS, EM-CONOS, EM-SCAN, CLEM), along with the full Bestron INSTEMS series of multi-environment in-situ TEM holders spanning mechanical (INSTEMS-M), thermal (INSTEMS-T), electrical (INSTEMS-E), thermal-electrical (INSTEMS-TE), mechanical-thermal (INSTEMS-MT), mechanical-electrical (INSTEMS-ME), and multi-field (INSTEMS-MET) configurations.
Differentiator
Problem solved
Functional benefit
Brands
- TVIPS: High-performance CMOS TEM cameras and imaging software systems, distributed exclusively in North America by Simple Origin.
- Bestron INSTEMS Series
Products and services
- Cryo Transfer Holder (Models 200, 201, 205, 210, 211, 220, 225)
Quantifiable outcome
- Steady-state drift below 3 nm/min with resolution better than 2 Å during regular operation
- +4 more outcomes
Companies that use Simple Origin
Customer profileNamed customers3 records
Segments3 records
Ideal customer profiles3 records
Simple Origin technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration10 records
Feature11 records
Simple Origin partnerships and signals
Strategic signalPartnerships
Nine partnerships are on record, tiered core and minor.
- TVIPS (Tietz Video and Image Processing Systems)coreSimple Origin is the exclusive North American representative for TVIPS, distributing their TemCam CMOS camera systems (XF416, XF216, XF416R) and imaging software (EM-MENU, EM-SPECTRO, EM-TOOLS, EM-CONOS, EM-SCAN, CLEM). TVIPS founder Hans Tietz serves as an advisor to Simple Origin.
- Bestron Science and TechnologycoreSimple Origin is the exclusive North American representative for Bestron ST INSTEMS series multi-environment in-situ TEM holders (INSTEMS-M, INSTEMS-T, INSTEMS-E, INSTEMS-MT, INSTEMS-MET, INSTEMS-TE, INSTEMS-ME).
- NORCADAcoreCollaboration with NORCADA for Cryogenic Heating/Biasing Holders using MEMS chip technology. NORCADA provides heating elements and SOLIS software for temperature control, integrated into Simple Origin holder hardware.
- TVIPS Japan G.K. (Dr. Shinji Aramaki)minorRegional sales and support partner for Japan market, located in Tokyo.
- M-Stumpf GmbH (Dr. Matthias Stumpf)minorRegional sales and service partner for EU region based in Germany. Dr. Matthias Stumpf also serves as advisor to Simple Origin.
- Milexia France SASminorRegional sales and service partner for France.
- Systems For ResearchminorRegional sales and service partner for Canada based in Etobicoke, Ontario.
- Beijing University of Technology Science ParkminorRegional sales and service partner for China, located in Beijing Tongzhou District.
- Drava Life Sciences Private LimitedminorRegional sales and service partner for India, located in Manipal.
Scale indicators1 record
Recent moves6 records
Expansion highlights5 records
Simple Origin competitors and assessment
Company assessmentMarket position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
Simple Origin financial estimates
Financial estimateRevenue estimate
Valuation estimate
Simple Origin leadership team
Management profileNumber of profiles
Profiles9 records
Simple Origin funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Simple Origin M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Simple Origin
What does Simple Origin do?
Simple Origin manufactures and distributes cryo-EM and TEM instrumentation for scientific research, including cryogenic transfer holders, inert gas/vacuum transfer holders, cryogenic heating/biasing holders, pumping assemblies, and inert gas workstations. The company also serves as the exclusive North American distributor for TVIPS TemCam CMOS camera systems and imaging software, as well as the Bestron INSTEMS series of multi-environment in-situ TEM holders. Products are designed for compatibility with Thermo Fisher (FEI), JEOL, and Hitachi TEM systems and target contamination-controlled cryo-EM, in-situ materials characterization, and semiconductor research workflows.
Is Simple Origin a public or private company?
Simple Origin is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Simple Origin founded?
Simple Origin was founded in -1. It employs 11 to 50 people.
Where is Simple Origin based?
Simple Origin is headquartered in Pittsburgh, United States, in the North America region.
How does Simple Origin make money?
Five revenue lines are on record. Cryogenic TEM Holders are the primary driver. The others are in-situ TEM Holders, TVIPS TEM Cameras, accessories and Pumping Assemblies and NORCADA MEMS Integration.
Does Simple Origin have an API?
No public API is recorded for Simple Origin.
What industry is Simple Origin in?
Simple Origin's product category is Electron Microscopy Instrumentation. Its primary akta.pro industry code is HLAGAIAJ, Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats), with a secondary code of HLAGAMAB, Cryogenic Logistics (LN2 Dry Shippers, -150°C). Its NAICS code is 334516 and its SIC code is 3826.