EuroFlow

What EuroFlow does

EuroFlow is a nonprofit research consortium established in 2006 with European Commission support (6th Framework Programme STREP) and operated under the umbrella of ESLHO (European Scientific foundation for Laboratory Hemato-Oncology), an official EHA Specialized Working Group. The consortium comprises 19 expert diagnostic research groups across 11 countries and develops, standardizes, and validates flow cytometry-based diagnostic tests for the diagnosis, prognostic classification, and minimal residual disease (MRD) monitoring of hematological malignancies, including leukemias, lymphomas, and multiple myeloma. Its core technology stack consists of standardized multi-color immunostaining protocols (8+ color panels), proprietary antibody tubes (LST, PIDOT, BCP-ALL MRD, ALOT, SST, PCST), novel immunobead assays for fusion-protein detection, and the Infinicyt analysis software (developed with partner Cytognos) that compares individual patient cases against disease-specific reference databases.

EuroFlow monetizes a portfolio of professional-services revenue streams rather than selling consumables directly: biannual External Quality Assessment (EQA) program fees (€270-€490 per round/scheme), educational course registration (€700 for 2-day, €1,400 for 4-5-day courses, with 50% academic discount), and workshop registration (~€185). Go-to-market is event-driven and educational, anchored by in-person Summer Schools, Winter Courses, PID Courses, and a new T/NK-cell course hosted at European university partners (University of Salamanca, Charles University Prague, University Hospital of Ghent, University of Rostock). Distribution is operated through the euroflow.org website, the ESLHO EQA Portal, and a long-standing channel partnership with BD (Becton Dickinson), which co-hosts workshops worldwide and whose FACSCanto II / Lyric instruments are referenced in EuroFlow SOPs. The customer base is clinical flow cytometry laboratories in over 35 countries, with the ESLHO-led EQA program recently pursuing ISO 17043 Proficiency Testing Provider accreditation to formalize lab certification.

Name

EuroFlow

Legal name

EuroFlow Consortium

Website

https://euroflow.org

Company type

Private

Founded year

2006

Operating status

Operating

Short description

EuroFlow is a 19-group, 11-country nonprofit research consortium that develops and standardizes flow cytometry diagnostic tests, antibody panels, and reference databases for hematological malignancy diagnosis and MRD monitoring, monetizing EQA certification fees, courses, and workshops for clinical laboratories worldwide.

Ownership category

akta.pro rank

Product category

Clinical Flow Cytometry Diagnostics

NAICS

Medical Laboratories (621511), Medical and Diagnostic Laboratories (62151), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Medical Laboratories (8071), In Vitro & In Vivo Diagnostic Substances (2835), Services-Misc Health & Allied Services, Nec (8090)

akta.pro primary industry

Flow Cytometry & Cellular Analysis Diagnostics (HLAHAAAF)

akta.pro secondary industries

Laboratory Developed Tests (LDTs) & Specialized Clinical Lab Assays (HLAAALAN), Oncology Diagnostics (tumor profiling, MRD, liquid biopsy) (HLAAALAE), Point-of-Care & Decentralized Trial Testing Services (HLAGAEAK)

Keywords

• Flow cytometry diagnostics
• Leukemia immunophenotyping
• Minimal residual disease monitoring
• External quality assessment
• Standardized diagnostic protocols

Headquarters

HQ city

Leiden

HQ country

Netherlands

HQ region

Europe

Offices6 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales

Revenue model

1. EQA Program Fees: External Quality Assessment program participation fees charged to laboratories for certification rounds. Participation in one round costs €270, both rounds of one scheme costs €490, with additional charges for multiple instrument certificates.
2. Educational Course Registration: Registration fees for in-person educational courses (1-5 days). Courses cost €1400 for 4-5 day courses and €700 for 2-day courses, with 50% discount for academic laboratory employees.
3. Workshop Registration: Registration fees for educational workshops organized in collaboration with BD and local institutions. Workshop fees typically around €185.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels7 records

Core offering

EuroFlow develops and disseminates standardized, multi-color flow cytometric diagnostic protocols, antibody panels, and reference databases for the diagnosis, prognostic classification, and minimal residual disease (MRD) monitoring of hematological malignancies. It runs an External Quality Assessment (EQA) program with four proficiency testing schemes and delivers in-person training through Summer Schools, Winter Courses, PID Courses, T/NK-cell courses, and BD-co-hosted workshops at partner universities worldwide.

Product overview

EuroFlow is a diagnostic research consortium offering a unified portfolio of standardized flow cytometric diagnostic products and services for hematological malignancies. The core offering consists of highly sensitive flow cytometric tests for diagnosis, prognostic classification, and MRD monitoring, supported by standardized SOPs, antibody panels (including LST, SST, PIDOT, ALOT), and Infinicyt-based analysis software with disease-specific reference databases. The portfolio also includes an External Quality Assessment Program with four proficiency testing schemes (LST, MM MRD, PIDOT, BCP-ALL MRD), and comprehensive education through workshops, courses, Summer/Winter Schools, and published educational materials. All components are designed to work together within the EuroFlow standardized ecosystem for consistent, high-quality flow cytometric diagnostics.

Differentiator

Problem solved

Functional benefit

Brands

• EuroFlow Campus: Educational platform offering courses, schools, and workshops for training in EuroFlow methods and flow cytometric diagnostics.
• EuroFlow EQA Program

Products and services

• EuroFlow LST EQA Scheme Biannual proficiency test using peripheral blood samples from three healthy donors, comparing participant results against reference data with performance scoring for the Lymphoid Screening Tube (LST). Targeted at clinical flow cytometry laboratories seeking certification.
• EuroFlow Multiple Myeloma MRD EQA Scheme External quality assessment for multiparametric flow cytometry detection of MRD in Multiple Myeloma patients, using FCS files from bone marrow samples processed with Next Generation Flow (NGF) methodology. Targeted at clinical laboratories performing MM MRD analysis.
• EuroFlow PIDOT EQA Scheme Two-part proficiency test including a wet lab component and dry analysis of FCS files for screening primary immunodeficiencies using the Primary Immunodeficiency Orientation Tube (PIDOT). Targeted at clinical immunology laboratories.
• EuroFlow BCP-ALL MRD EQA Scheme Combined wet lab and dry analysis proficiency test using files from BCP-ALL patients merged with control files for comprehensive MRD assessment. Targeted at clinical flow cytometry laboratories performing B-ALL MRD analysis.
• EuroFlow Summer School Five-day intensive course training experienced clinical cytometrists on EuroFlow procedures, panel analysis, and use of Infinicyt databases for diagnosis of leukemias and lymphomas. Limited to 24 participants for hands-on case-solving and optional laboratory module, hosted at the University of Salamanca.
• EuroFlow Winter Course on MRD Three-day course focused on Minimal Residual Disease analysis in B-ALL, T-ALL, Multiple Myeloma, and Chronic Lymphatic Leukemia with hands-on case-solving sessions. Hosted at Charles University, Prague.
• EuroFlow Course on T/NK-cell Neoplasms Five-day course on immunophenotypic profiling of T-cell and NK-cell neoplasms, covering diagnosis, clonality assessment, classification, and flow cytometry monitoring through a case-based approach. Hosted at the University of Salamanca.
• EuroFlow PID Course Advanced course on application of flow cytometry in diagnosis and classification of Primary Immunodeficiencies, based on the EuroFlow PID algorithm and PIDOT panel. Hosted at the University Hospital of Ghent, Belgium.
• EuroFlow Educational Workshops Two-day in-person educational workshops organized in collaboration with BD and local institutions in countries including Germany, Vietnam, Malaysia, Egypt, Canada, Brazil, Colombia, Mexico, China, and Australia. Targeted at local clinical cytometrists seeking hands-on protocol training.
• EuroFlow Educational Books Published educational reference books covering EuroFlow-based diagnosis and classification of acute leukemias, mature B- and T-cell malignancies, and primary immunodeficiencies (2nd Version). Targeted at clinical laboratories implementing EuroFlow standardized approaches.
• EuroFlow Standard Operating Procedures (SOPs) Standardized immunostaining protocols for diagnosis, classification, prognostic subclassification, and MRD detection during follow-up of hematological malignancies. Distributed via the EuroFlow login area; supports consistent lab routines across centers.

Quantifiable outcome

• Standardized detection of MRD during follow-up of hematological malignancies
• +2 more outcomes

Named customers5 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Seven partnerships are on record, tiered core, major and minor.

• ESLHO (European Scientific foundation for Laboratory Hemato-Oncology)coreStrategic or Co-development Partner · 1 January 2006ESLHO supports EuroFlow and is an official EHA Specialized Working Group. ESLHO organizes the EuroFlow EQA program in collaboration with EuroFlow Consortium members and has formally adopted the organization of EuroFlow EQA schemes. Also associated with EuroClonality and EuroMRD.
• BD (Becton Dickinson)majorChannel Partner/ Reseller/ DistributorBD-EuroFlow Workshops are conducted worldwide, with BD collaborating on educational workshops. Workshops mention BD FACSCanto IITM instruments and BD Lyric in protocols. BD EuroFlow Workshop series held in multiple countries.
• University of SalamancamajorStrategic or Co-development PartnerUniversity of Salamanca hosts EuroFlow Summer Schools and educational courses. Faculty from University of Salamanca (Prof. Dr. Alberto Orfao, Dr. Juan Flores Montero, Dr. Carlos Fernandez, Dr. Cristina Teodosio) serve as lecturers.
• Charles University PraguemajorStrategic or Co-development PartnerCharles University hosts EuroFlow Winter Course on MRD in Prague. Prof. Dr. Tomas Kalina (lead expert for LST EQA scheme) and Dr. Michaela Reiterova (lead expert for BCP-ALL MRD EQA scheme) are affiliated with Charles University.
• University Hospital of GhentmajorStrategic or Co-development PartnerOrganizes EuroFlow PID courses in cooperation with University Hospital of Ghent. Prof. Dr. Carolien Bonroy (lead expert for PIDOT EQA scheme) is from University of Ghent.
• International Myeloma Foundation (IMF)minorStrategic or Co-development PartnerIMF collaborated on Next Generation Flow Workshop for MM MRD detection. IMF-EuroFlow Workshop on automated, highly sensitive flow cytometry method for standardized detection of MRD in MM held in Salamanca.
• ESCCA (European Society for Clinical Cell Analysis)minorGTM or Marketing PartnerEuroFlow exhibits at ESCCA conferences to distribute educational books and promote Quality Assessment programs. Also presents at ESID conferences.

Scale indicators8 records

Recent moves8 records

Expansion highlights5 records

Emerging players

• Natera: Provider of Signatera tumor-informed MRD testing using ctDNA. While focused on solid tumors today, Natera represents the broader competitive pressure from NGS/molecular MRD players that could encroach on EuroFlow's hematological MRD market over time.
• Adaptive Biotechnologies: US-based company behind the clonoSEQ NGS-based MRD assay, FDA-approved for CLL, ALL, and MM. Represents the molecular alternative to EuroFlow's flow cytometry-based MRD methods and a potential long-term substitute for some clinical indications.
• Cytognos: Spanish biotech developing Infinicyt, the proprietary analysis software that powers EuroFlow's reference database workflow. As the exclusive software partner, Cytognos is tightly coupled to EuroFlow's product offering and represents an enabling rather than competing participant in the ecosystem.

Broad incumbents

• Bio-Rad Laboratories: Flow cytometry instrument manufacturer (ZE5, S3) with a clinical diagnostics focus. Competes for the same hematology laboratory customers as EuroFlow's standardized protocols and offers competing CE-IVD flow cytometry antibody panels.
• Becton Dickinson (BD): Major flow cytometry instrument manufacturer (FACSCanto II, BD Lyric) and EuroFlow's largest commercial partner for global workshops. While primarily an instrument vendor, BD's Life Sciences segment competes broadly for the same hematology laboratory budgets that fund EuroFlow's standardization ecosystem.
• Sysmex Europe: Major hematology diagnostics company with flow cytometry product lines serving European clinical labs. Represents a broad incumbent alternative for hematology laboratories considering turnkey flow cytometry solutions versus EuroFlow's standardized protocols.
• Beckman Coulter Life Sciences: Major flow cytometry instrument and reagent provider (Navios, CytoFLEX, DxFLEX) competing for the same clinical flow cytometry laboratories that adopt EuroFlow protocols. Offers proprietary standardized panels that overlap with EuroFlow's standardized reagent tubes.
• ESLHO (European Scientific foundation for Laboratory Hemato-Oncology): Parent foundation that supports EuroFlow, EuroClonality, and EuroMRD and is recognized as an EHA Specialized Working Group. Now operates the consolidated EQA platform across all three consortia and provides the closest structural analog to EuroFlow's mission.

Direct peers

• EuroMRD: Sister consortium for standardized MRD testing in leukemias and lymphomas, also operating under ESLHO. Directly comparable in consortium structure, EQA scheme model, and target customer base of clinical flow cytometry laboratories.
• EuroClonality: Sister consortium under the same ESLHO umbrella, focused on standardized clonality testing for hematological malignancies. Shares the same organizational model, EQA program, and educational infrastructure as EuroFlow, and its EQA schemes were consolidated with EuroFlow under ESLHO in 2024-2025.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Funding overview

Funding rounds

Investors

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M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about EuroFlow