What Mythos does

Mythos Co., Ltd. (株式会社ミュートス) is an Osaka-headquartered Japanese B2B software provider, founded in August 2006 and operating as a wholly-owned subsidiary of PharmaRise Holdings (ファーマライズホールディングス株式会社). The company specializes in CRM, SFA, and adverse-event information management systems for domestic pharmaceutical manufacturers and medical device companies. Its product portfolio centers on MESICOT (メシコ) for adverse-event case collection and PMDA reporting workflows, Co-ReFit (コ・リフィット) as an SFA/CRM platform for medical representatives with AI-assisted reporting features, STOTCH (ストッチ) for multi-location retail employee engagement, M-Chat (エムチャット) for MR/MS real-time communication, and Chit (チャット), a free multi-character AI group chat application launched in October 2025.

The underlying technology is a cloud-based SaaS stack built on PHP, Java, VueJS, and jQuery, supported by MySQL, MariaDB, PostgreSQL, Oracle, and SQL Server, and deployed across AWS, Azure, and GCP using Docker and Vagrant. AI capabilities are layered through a 2019 Gold-tier partnership with FRONTEO for the KIBIT natural language engine (used for NG-word detection, activity trend analysis, and adverse-event case matching), supplemented by in-house generative AI features added to Co-ReFit in June 2026 in beta. MESICOT and Co-ReFit integrate with EPPV/PMS systems, distributor master data, Google Calendar, and other enterprise systems via documented templates derived from prior implementations at major Japanese pharmaceutical manufacturers.

Mythos earns revenue through a mix of subscription-based cloud services (MESICOT Basic/Light, Co-ReFit, STOTCH on monthly billing), project-based system integration services for custom development, and one-time software licensing for template-based deployments. Go-to-market is primarily direct enterprise field sales supported by trade-show participation (Pharma DX EXPO Tokyo and Osaka) and product-specific microsites. Customer concentration is in the pharmaceutical vertical, with 19 disclosed Co-ReFit customers and additional MESICOT and STOTCH deployments; the company is privately held under its parent group and does not disclose revenue.

Name

Mythos

Legal name

株式会社ミュートス

Website

https://mythos-jp.com

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

11–50 employees

Short description

Mythos Co., Ltd. (株式会社ミュートス) is an Osaka-based Japanese B2B software vendor specializing in CRM, SFA, and adverse-event management systems for domestic pharmaceutical manufacturers. Its portfolio includes MESICOT, Co-ReFit, STOTCH, M-Chat, and Chit AI, serving roughly 19 disclosed pharma customers as a wholly-owned subsidiary of PharmaRise Holdings.

Ownership category

akta.pro rank

Product category

Pharmaceutical CRM and SFA Software

NAICS

Software Publishers (51321)

SIC

Services-Computer Programming Services (7371)

akta.pro primary industry

Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

Keywords

• Pharmaceutical SFA systems
• Adverse event management
• Pharma CRM software
• Safety information systems
• Medical representative tools

Headquarters

HQ city

Osaka

HQ country

Japan

HQ region

Asia

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. System Integration Services: Custom Web system development, smartphone app development, and operational maintenance services for pharmaceutical and medical device companies. Services include consulting through development and maintenance, typically delivered as project-based engagements with upfront customization.
2. Cloud Service Subscriptions: SaaS products including MESICOT (adverse event management), Co-ReFit (pharma SFA), and STOTCH (store management). Offered as cloud services with monthly or annual subscription billing. Basic/Light plan tiers available. Includes AWS cloud-based private cloud or on-premise options.
3. Software Product Licensing: Customization-based product deployment with template-based development approach offering shorter timelines and lower costs compared to full custom development.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels4 records

Core offering

Mythos develops and sells specialized cloud-based software systems for the Japanese pharmaceutical and medical device industry, including MESICOT (adverse event information collection and management), Co-ReFit (pharmaceutical SFA/CRM for medical representatives), STOTCH (store management groupware), and M-Chat (real-time MR/MS communication). The company also provides custom system integration, consulting, and maintenance services for pharmaceutical clients, with templates derived from systems deployed at major Japanese pharmaceutical manufacturers.

Product overview

Mythos offers a portfolio of specialized systems for the pharmaceutical and healthcare industry plus cross-industry cloud services. The core product lineup includes MESICOT for adverse event information collection management, Co-ReFit as the flagship SFA/CRM system for pharmaceutical MRs, STOTCH for store employee consciousness reform, M-Chat for MR-MS real-time communication, and Chit as the company's first AI service. MESICOT and Co-ReFit form the primary pharmaceutical sector offering, with MESICOT handling safety information workflows and Co-ReFit supporting sales activity management. STOTCH extends the portfolio to retail/cross-industry store management. Services include system integration (custom development), cloud services (SaaS products), and specialized systems for EPPV/PMS, actual sales data, and event management.

Differentiator

Problem solved

Functional benefit

Brands

• MESICOT（メシコ）: 副作用情報の収集管理業務に特化したシステム。製薬企業の安全管理部門やMRの業務を支援する。
• Co-ReFit（コ・レフィット）
• STOTCH（ストッチ）
• M-Chat（エムチャット）
• Chit（チット）

Products and services

• MESICOT (メシコ) Adverse event (side effect) information collection and management system for pharmaceutical safety management departments and medical representatives, supporting intake from multiple channels (MR reports, literature, call centers, FAX), online reporting by external reporters, investigation progress tracking, history management, and complaint management. Offered as cloud SaaS with Basic and Light plan tiers.
• Co-ReFit (コ・リフィット) Web-based SFA/CRM system for pharmaceutical company sales departments, supporting medical representative activity reporting, planning, physician relationship management, Google Calendar synchronization, content management, and AI-powered activity support (report drafting, quality checking, conversation simulation). Deployed across 19 pharmaceutical companies.
• STOTCH (ストッチ) Cloud-based groupware for multi-location retail businesses targeting store employee awareness reform, goal tracking, customer information sharing, bulletin board, shift management, thank-you recognition, and customer memo functions. Available in Basic (all features) and Light (3 selected features) plan tiers.
• M-Chat (エムチャット) Real-time chat service for pharmaceutical company medical representatives (MR) and medical specialists (MS), supporting instant information sharing, voice input via OS functionality, and NG word configuration to enforce compliance with sales information provision guidelines.
• Chit (チャット) AI group chat application where users converse with multiple AI characters in a group chat format for consultation and discussion. Free service developed as Mythos's first AI product, with chat content not used for secondary purposes.

Quantifiable outcome

• Side effect reporting speed improved through online reporting function eliminating MR data entry bottleneck
• +3 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability5 records

Feature4 records

Partnerships

Four partnerships are on record, tiered core and flagship.

• 株式会社FRONTEO (FRONTEO Inc.)coreTechnology or Integration · 30 September 2019Partnership for KIBIT natural language processing AI engine integration into pharmaceutical and dispensing pharmacy services. Mythos became the first Gold Partner in the KIBIT Partner Network. KIBIT enables activity trend analysis from reports and guideline compliance checking for MR activities, as well as past case matching and inquiry simplification for MESICOT.
• RPAテクノロジーズ株式会社 (RPA Technologies Inc.)coreTechnology or Integration · 14 May 2019Partnership for BizRobo! RPA product distribution and implementation support targeting pharmaceutical and dispensing pharmacy companies. Mythos provides RPA introduction support including implementation, operation, and consulting services for business process automation.
• 株式会社フラジェリン (Flagellin Inc.)coreStrategic or Co-development Partner · 29 August 2018Business partnership for co-development of analysis and sales support cloud services for pharmaceutical industry. Flagellin provides ML-powered automated analysis engine and databases; Mythos provides implementation support, customization, and ongoing operational maintenance.
• ファーマライズホールディングス株式会社 (PharmaRise Holdings Co., Ltd.)flagshipOthersParent company. Owns dispensing pharmacy chain and healthcare-related businesses. Mythos provides system development services and shares corporate infrastructure. Located in Osaka with group company discount programs available to Mythos employees.

Scale indicators5 records

Recent moves13 records

Expansion highlights5 records

Regional players

• NTT Data: Large Japanese system integrator with a pharmaceutical industry practice. Provides custom system development and IT services to Japanese pharmaceutical companies, overlapping with Mythos's system integration services.
• NTT Data: Large Japanese system integrator with a dedicated pharmaceutical industry practice. Provides custom system development, CRM, and IT services to Japanese pharmaceutical manufacturers, overlapping with Mythos's system integration and Co-ReFit SFA offerings.

Broad incumbents

• IQVIA: Global leader in pharma analytics, technology solutions, and commercial services. Offers CRM and physician engagement solutions for pharmaceutical companies alongside data and consulting services.
• Salesforce: Largest general-purpose CRM platform with Life Sciences Cloud and Health Cloud offerings for pharmaceutical companies. Competes in the pharma CRM space but as part of a much broader portfolio rather than specializing in pharma workflows.
• Oracle Health Sciences: Clinical trial, pharmacovigilance, and pharma CRM technology (former Cerner, Siebel). Provides broad pharma IT portfolio including clinical trial informatics and safety systems that overlap with Mythos's adverse event management.

Direct peers

• Veeva Systems: Global leader in cloud-based CRM, SFA, and regulatory solutions for life sciences. Most directly comparable to Mythos as both serve pharmaceutical sales organizations with CRM/SFA offerings, though Veeva operates at significantly larger scale internationally.
• ArisGlobal: Provider of pharmacovigilance, regulatory affairs, and drug safety software for life sciences. Directly comparable to Mythos's MESICOT adverse event information collection and management system.
• Sparta Systems (Honeywell): Quality management and complaint handling software for life sciences (TrackWise). Overlaps with Mythos's MESICOT complaint management function and pharma quality system offerings.

Others

• FRONTEO: AI company providing the KIBIT natural language processing engine. Mythos's first Gold partner in the KIBIT Partner Network, integrated into MESICOT for case matching and Co-ReFit for report quality checking.
• RPA Technologies (BizRobo!): RPA software vendor behind BizRobo!. Mythos's distribution and implementation partner for RPA automation targeting Japanese pharmaceutical and dispensing pharmacy customers.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Mythos