What U.S. Biotech Sources does

U.S. Biotech Sources, LLC is a privately held biochemical reagent supplier founded in 2000 and headquartered in San Pablo, California, with an additional office in Richmond, CA. The company develops and sells a catalog of biological reagents for life science research, spanning protein purification resins (His-tag, Protein A, GST affinity, plus size exclusion and enzyme immobilization beads), DNA/RNA extraction and purification kits, protein extraction and staining kits, protein molecular weight markers, pre-mixed culture media, peptones, and fine chemicals. Proprietary, trademarked product lines include SuperPure™ Agar and Agarose LE, SuperSieve™ 3:1 Agarose, SuperPremix™ LB Broth and Agar formulations, and the Rapid Run™ high-flow chromatography resin line. The company explicitly states it also pursues drug discovery work focused on anti-cancer therapeutics, though there is no disclosed pipeline, indication, or stage detail for this activity in the available data.

The business operates a direct-to-customer sales model, with orders accepted via telephone, email, and fax during U.S. business hours, supplemented by an e-commerce-enabled catalog on usbiotechsources.com. Pricing is per-unit with explicit volume and long-term customer discounts; peptones and fine chemicals are quote-based for bulk packages up to 50 kg. The customer base is anchored in academic research laboratories, with named adopters including the University of California Berkeley, Davis, and San Francisco, plus biotechnology industry customers in the U.S. and Asia. International reach is enabled through a distribution partnership with Homeogenics Biotechnology Inc., based in Beijing's Zhongguancun Science Park, covering the Chinese market. The firm is structured as a California LLC with 11-50 employees, no disclosed funding rounds, no M&A activity, and no patents or regulatory filings disclosed in the source material.

Name

U.S. Biotech Sources

Legal name

U.S. Biotech Sources, LLC

Website

https://usbiotechsources.com

Company type

Private

Founded year

2000

Operating status

Operating

Headcount range

11–50 employees

Short description

U.S. Biotech Sources is a California-based biochemical reagent supplier that develops and sells protein purification resins, DNA/RNA extraction kits, culture media, and peptones to academic research laboratories and biotech companies in the U.S. and Asia via direct sales and a Beijing distributor.

Ownership category

akta.pro rank

Product category

Life Science Reagents

NAICS

Medicinal and Botanical Manufacturing (325411)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industries

Raw Materials & Critical Reagents Supply (Media/Resins/Cytokines) (HLAGAGAI), Bioprocess Consumables & Reagents (resins, membranes, media components, buffers) (HLAAAJAI), Raw Materials & Critical Reagents Supply Services (media, resins, single-use) (HLAAAKAI)

Keywords

• Biological reagents
• Protein purification
• DNA RNA extraction
• Cell culture media
• Life science research

Headquarters

HQ city

Richmond

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Marketing or Sales, Technology or R&D

Revenue model

1. Biological Reagent Sales: The company generates revenue through the sale of biological reagents including protein purification products, DNA/RNA extraction and purification kits, culture media, peptones, and fine chemicals. Products are sold in various package sizes (grams to kilograms) with unit pricing.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels2 records

Core offering

U.S. Biotech Sources manufactures and supplies biological reagents for life science research, including protein purification products (His-tag, Protein A, GST affinity chromatography resins, and size exclusion chromatography beads), DNA/RNA extraction and purification kits, culture media pre-mixes, peptones, protein extraction/staining kits, protein markers, and fine chemicals. Products are sold in package sizes from research-scale (grams) to industrial-scale (kilograms) via the company's own website, telephone, email, and an international distributor network.

Product overview

U.S. Biotech Sources is a biotechnology reagent and laboratory supplies company offering a comprehensive portfolio of biological reagents for life science research. The company operates as a single-brand supplier with a focused product line organized into distinct categories: (1) Culture Media & Pre-Mix products including SuperPure™ Agar, Agarose LE, SuperSieve™ 3:1 Agarose, Tryptone, Yeast Extract, and SuperPremix™ LB Broth/Agar formulations; (2) Protein Products encompassing extraction kits for bacterial, mammalian, yeast, and plant samples, protein purification systems using His-tag affinity chromatography, Protein A/GST purification resins, enzyme immobilization beads, and size exclusion chromatography beads (Plain, Crosslinked, and Rapid Run™ Agarose Beads); (3) Molecular Biology Products including RNA and DNA extraction/purification kits for diverse sample types, gel extraction, and PCR cleanup kits; (4) Protein Markers in various molecular weight ranges; (5) Peptones and Fine Chemicals. These products serve research laboratories at universities including UC Berkeley, Davis, and UCSF, as well as biotech industries in the U.S. and Asian countries.

Differentiator

Problem solved

Functional benefit

Brands

• SuperPure™: Product line including SuperPure Agar and SuperPure Agarose LE for bacteriological and molecular biology applications
• SuperPremix™
• SuperSieve™
• Rapid Run™
• Chelating Agarose Beads

Products and services

• SuperPure™ Agar Bacteriological grade agar available in powder and granulated forms, used as a solidifying agent in culture media for microbiology applications. Targeted at research laboratories in academic and biotech settings.
• SuperPure™ Agarose LE Molecular biology grade agarose for DNA/RNA gel electrophoresis, offering high purity and resolution. For research laboratories conducting nucleic acid analysis.
• SuperSieve™ 3:1 Agarose Molecular biology grade agarose with specialized sieving properties for DNA separation applications. For research laboratories needing size-selective nucleic acid separation.
• SuperPremix™ Culture Media Pre-Mixes Pre-mixed LB Broth and LB Agar formulations (Miller and Lennox variants) for cultivation of E. coli and other bacteria in molecular biology applications. Targeted at research laboratories.
• Protein Extraction Kits Kits for extracting proteins from bacterial, mammalian, yeast, plant, and inclusion body samples, including a Protein Right Folding Kit for refolding misfolded proteins. For research laboratories performing proteomics and protein analysis.
• Protein Staining Kits Kits for detecting and visualizing proteins in polyacrylamide gels, including glycoprotein staining, phosphoprotein staining, Coomassie Blue staining, and silver stain destaining. For research laboratories performing protein analysis.
• His-Tag Purification (Chelating Agarose Beads) Immobilized metal affinity chromatography (IMAC) beads for purification of His-tagged recombinant proteins, available with Nickel, Zinc, Cobalt, or Copper metals in various formats. For research laboratories and biotech companies performing recombinant protein purification.
• Chelating Rapid Run™ Agarose Beads High-flow-rate IMAC beads combining metal affinity purification with Rapid Run™ agarose technology for large-scale His-tagged protein purification, offering 70% higher flow rates than standard commercial resins. For process-scale protein purification in biotech and industrial research.
• Protein A Agarose Beads Protein A conjugated agarose beads for affinity purification of antibodies and immunoglobulins from various mammalian species. For research laboratories performing antibody purification.
• Glutathione Agarose Beads Affinity chromatography resin for purification of GST-tagged fusion proteins and glutathione-binding enzymes, available in bulk resin and cartridge formats. For research laboratories performing GST-tag protein purification.
• Size Exclusion Chromatography Resins Size exclusion chromatography (gel filtration) beads for protein separation by molecular size, including Plain Agarose Beads, Crosslinked Agarose Beads, and Rapid Run™ Agarose Beads in multiple concentrations and particle sizes. For research laboratories and process-scale protein separations.
• Glyoxal and Aminoethyl Agarose Beads Pre-activated agarose beads for covalent immobilization of enzymes and antibodies through lysine amino groups (Glyoxal) or acidic amino acid groups (Aminoethyl), eliminating the need for activation steps. For research laboratories performing enzyme immobilization and antibody purification.
• Protein Markers Pre-stained protein molecular weight markers in various ranges (High, Mid, Low, Wide Range, Broad Range SDS-PAGE Standards) for SDS-PAGE gel calibration and molecular weight determination. For research laboratories performing protein electrophoresis.
• DNA Extraction Kits Comprehensive DNA extraction solutions for genomic DNA from animal, bacterial, blood, plant, tissue, plasmid, hair, insect, soil, stool, and viral samples, available in mini-prep, midi-prep, and maxi-prep formats. For research laboratories performing genomic DNA isolation.
• RNA Extraction Kits Complete kits for total RNA and mRNA extraction from various sample types including animal tissues, blood, plant, fungal, bacterial, viral, and clinical samples, available in multiple formats and throughput options. For research laboratories performing RNA isolation.
• DNA/RNA Purification and Specialty Kits Specialized molecular biology kits including DNA Gel Extraction, PCR Products Purification, Apoptotic DNA Ladder Detection, Single Colony Screening (PCR-EZ A2), Random Priming DNA Labeling, and Tiny Sample DNA/RNA Recovery. For research laboratories performing downstream molecular biology workflows.
• Peptones Extensive line of peptone products including beef extract, heart infusion, brain heart infusion, casein peptone, gelatin peptone, meat peptone, soy peptone, marine peptone, and specialty peptones for culture media preparation. For research laboratories and biotech companies preparing microbiological culture media.
• Fine Chemicals Selection of commonly used antibiotics and molecular biology reagents including Ampicillin, Kanamycin, Tetracycline, X-Gal, MU-gal, and IPTG for bacterial selection and induction applications. For research laboratories performing molecular biology and microbiology research.

Quantifiable outcome

• Products widely used by research laboratories at major UC campuses and other universities
• +1 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature10 records

Partnerships

One partnership is on record.

• Homeogenics Biotechnology Inc.minorChannel Partner/ Reseller/ DistributorHomeogenics Biotechnology Inc. is a distributor of U.S. Biotech Sources products in China, located at Zhong guan cun Science Park in Hai Dian District, Beijing, China. The company联系方式 is Tel. 13326616855. This is part of U.S. Biotech Sources' strategy to expand distribution channels internationally.

Scale indicators2 records

Recent moves5 records

Expansion highlights5 records

Direct peers

• GenScript: Direct peer in molecular biology reagents, protein purification tools, and biotech research services, with overlapping DNA/RNA extraction kits and custom reagent offerings targeting academic and biotech customers.
• Gold Biotechnology: Similar-sized U.S. reagent supplier focused on antibiotics, fine chemicals, culture media, and molecular biology reagents — directly overlapping U.S. Biotech Sources' fine chemicals (ampicillin, kanamycin, IPTG, X-Gal) and peptone categories with comparable budget pricing.
• Bio-Rad Laboratories: Direct competitor across protein purification resins, gel electrophoresis reagents, and life science research consumables. Bio-Rad's Profinity IMAC, Affi-Gel, and agarose product lines overlap directly with U.S. Biotech Sources' chelating beads, Protein A/GST resins, and SuperPure™ agarose lines.
• Research Products International: Comparable mid-sized U.S. reagent supplier offering culture media components, antibiotics, biochemicals, and life science research consumables — competing in nearly identical categories (peptones, agar, fine chemicals) with similar budget pricing strategy.
• Cell Signaling Technology: Specialized peer in protein research reagents including antibodies, protein extraction/lysis tools, and protein purification products — overlapping with U.S. Biotech Sources' protein extraction kits, staining kits, and affinity purification resins.
• New England Biolabs: Specialist in molecular biology reagents and kits, including DNA/RNA purification and protein tools. Overlaps with U.S. Biotech Sources' molecular biology product line, though NEB is more enzyme-focused while U.S. Biotech Sources is broader in extraction and protein workflows.

Broad incumbents

• Thermo Fisher Scientific: Dominant life science tools incumbent covering protein purification (Ni-NTA, Protein A resins), culture media, antibiotics, and molecular biology kits across Invitrogen, Thermo Scientific, and Gibco brands. Competes with U.S. Biotech Sources on essentially every product line, with vastly greater scale.
• Merck KGaA / MilliporeSigma: Broad incumbent supplying the research reagents catalog most directly comparable to U.S. Biotech Sources' portfolio — agar, agarose, peptones, antibiotics, IPTG, X-Gal, protein extraction kits, and affinity purification resins — under the Sigma-Aldrich and Millipore brands.
• Cytiva (Danaher): Global leader in chromatography resins and bioprocessing consumables, including MabSelect Protein A, Ni-Sepharose, and size-exclusion matrices that directly compete with U.S. Biotech Sources' affinity and size-exclusion agarose bead lines, especially in process-scale applications.

Emerging players

• Tocris Bioscience (Bio-Techne): Specialty supplier of life science research reagents including biochemicals and protein research tools. Partial overlap with U.S. Biotech Sources' fine chemicals and protein reagent categories, though Tocris is more focused on small-molecule bioactive compounds.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks6 records

Key highlights7 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about U.S. Biotech Sources