Colorado Serum Company

What Colorado Serum Company does

Colorado Serum Company is a privately held US manufacturer of veterinary biologicals and laboratory reagents, founded in 1923 and headquartered in Denver, Colorado. The company operates two product segments. The veterinary biologicals segment produces vaccines, bacterins, antitoxins, and serum antibody products for livestock species (cattle, sheep, goats, swine, horses), covering clostridial diseases (tetanus, blackleg, enterotoxemia), anthrax, brucellosis, leptospirosis, salmonellosis, pasteurellosis, chlamydiosis, campylobacteriosis, contagious ecthyma, and respiratory pathogens. Manufacturing relies on in-house donor animal herds of equine, bovine, ovine, caprine, and guinea pig origin, with killed bacterial products using aluminum hydroxide or oil adjuvants, live attenuated vaccines, toxoids, and serum antibody formulations; all serials undergo sterility testing (HI, Thioglycollate, Tryptic Soy) and equine-origin serials are subject to USDA-mandated qPCR testing for EqPV-H. The laboratory reagent segment produces red blood cells in multiple anticoagulant formats (alsevers, citrated, defibrinated) from sheep, rabbit, calf, goat, and guinea pig, plus pooled normal sera, guinea pig complement (frozen and lyophilized), hemolysin, and Freund's adjuvants for veterinary in-vitro research use. Products are sold exclusively through a network of authorized US distributors for the biologicals segment, with laboratory reagents shipped directly to customers via UPS Next Day Air. The company is licensed by USDA/APHIS/Center for Veterinary Biologics, operates a basic e-commerce catalog site, and produces educational content through a "Vets Corner" blog authored by staff veterinarians.

Name

Colorado Serum Company

Legal name

Colorado Serum Company

Website

https://colorado-serum-com.3dcartstores.com

Company type

Private

Founded year

1923

Operating status

Operating

Headcount range

101–250 employees

Short description

Colorado Serum Company is a privately held Denver-based manufacturer, founded in 1923, producing USDA-licensed veterinary vaccines, antitoxins, and serum products for livestock plus laboratory reagents, sold through authorized US distributors.

Ownership category

akta.pro rank

Product category

Veterinary Biologicals

NAICS

Veterinary Services (54194)

SIC

Biological Products, (No Disgnostic Substances) (2836), In Vitro & In Vivo Diagnostic Substances (2835), Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047)

akta.pro primary industry

Veterinary Vaccines (Biologics) (HLAMAEAL)

akta.pro secondary industries

Livestock Vaccines (Cattle, Swine, Sheep & Goats) (HLAMAKAB), Veterinary Vaccine & Biologics Distributors (HLAMAIAC), Reference Laboratory Testing (Clinical Pathology & Chemistry) (HLAMADAA)

Keywords

• Veterinary biologicals
• Livestock vaccines
• Animal disease prevention
• Veterinary diagnostics reagents
• Serum antibody products

Headquarters

HQ city

Denver

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Supply Chain, Technology or R&D, Others

Revenue model

1. Veterinary Biological Products: Colorado Serum Company generates revenue through the sale of veterinary biological products including vaccines, bacterins, toxoids, and antitoxins for livestock animals. Products are sold through authorized distributors with pricing based on dose size and product type.
2. Laboratory Reagent Products: Sale of laboratory reagents including red blood cells, serum products, complement, and hemolysin for veterinary in-vitro research use. These products are priced separately from biologicals and shipped UPS Next Day Air with additional shipping charges.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels3 records

Core offering

Colorado Serum Company manufactures and distributes veterinary biological products including vaccines, bacterins, toxoids, antitoxins, and serum antibody products for livestock species (cattle, sheep, goats, swine, horses). The company also produces laboratory reagents such as red blood cells, pooled normal sera, guinea pig complement, hemolysin, and Freund's adjuvants for veterinary diagnostic and research applications. Manufacturing is performed under USDA/APHIS/CVB licensure using in-house donor animal herds with veterinary supervision.

Product overview

Colorado Serum Company is a manufacturer and distributor of veterinary biologicals and laboratory reagents established in 1923. The product portfolio consists of two main segments: (1) Veterinary Biologicals including vaccines, antitoxins, and bacterins for livestock (cattle, sheep, goats, swine, horses) covering diseases such as tetanus, anthrax, blackleg, salmonella, leptospirosis, and respiratory pathogens; and (2) Laboratory Reagent Products including red blood cells (in various anticoagulant formats: alsevers, citrated, defibrinated), pooled normal sera, guinea pig complement, hemolysin, and Freund's adjuvants. The biologicals segment includes branded product lines: Essential vaccines (Essential 1, 2, 3, 3+T), tetanus products (antitoxin and toxoid formulations), BOVI-SERA serum antibodies, and PULMO-CLEAR immunomodulator. Products are sold through distributors to veterinarians and livestock producers. Some equine serum origin products have faced production constraints due to USDA-mandated EqPV-H testing requirements.

Differentiator

Problem solved

Functional benefit

Brands

• Colorado Serum Biologicals: Primary product line of biological veterinary products
• Professional Biologicals
• Laboratory Reagent Products

Products and services

• Tetanus Antitoxin Equine origin serum product prepared from hyperimmunized horses, used as an aid in the prevention and treatment of tetanus in cattle, sheep, goats, and swine. Contains phenol and thimerosal as preservatives.
• Clostridium Perfringens Types C&D Antitoxin Multivalent equine-origin antitoxin for temporary prevention or treatment of clostridial enterotoxemia in cattle, sheep, goats, and swine caused by Types B, C, and D toxin.
• Normal Equine Serum Equine origin serum for non-specific treatment of equine infections and disease conditions, providing supplemental equine albumin, globulins, and associated fluids.
• Essential 2 Double bacterin for vaccination of healthy cattle, sheep, and goats against Blackleg (Clostridium chauvoei) and Malignant Edema (Clostridium septicum) with aluminum hydroxide adjuvant.
• Essential 1 Bacterin for prevention of Red Water Disease (Bacillary Hemoglobinuria) caused by Clostridium haemolyticum in cattle, sheep, and goats.
• Essential 3 Multi-valent clostridial vaccine providing protection against multiple clostridial diseases in cattle.
• Essential 3 + T Multi-valent clostridial vaccine with tetanus protection for cattle.
• Anthrax Spore Vaccine Live attenuated bacterial vaccine using Sterne Strain 34F2 of Bacillus anthracis for vaccination of healthy cattle, sheep, goats, swine, and horses against anthrax.
• BOVIB-LEPTO 5 Combination vaccine for cattle preventing infertility, delayed conception, abortions, and losses from Campylobacter fetus, Leptospira canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona.
• BOVI-SERA Bovine origin serum antibody product for prevention and treatment of enteric and respiratory conditions in cattle and sheep caused by multiple pathogens including Arcanobacterium pyogenes, E. coli, Mannheimia haemolytica, Pasteurella multocida, and Salmonella typhimurium.
• Brucella Abortus Vaccine - Strain RB-51 Attenuated live bacterial vaccine for prevention of Brucella abortus infection and abortion in healthy female cattle 4-12 months of age. Licensed veterinarian purchase required.
• RESPIRA-3 Respiratory vaccine for cattle and calves preventing disease caused by Bovine Rhinotracheitis virus, Bovine Virus Diarrhea virus (BVDV), and Parainfluenza 3 virus.
• LEPTO 5 Leptospira bacterin for prevention of leptospirosis in cattle and swine caused by Canicola, Grippotyphosa, Hardjo, Icterohaemorrhagiae, and Pomona organisms.
• Mannheimia Haemolytica-Pasteurella Multocida Bacterin Killed bacterial vaccine for cattle, sheep, and goats against respiratory disease caused by Mannheimia haemolytica and Pasteurella multocida.
• Tetanus Toxoid - Concentrated Detoxified tetanus toxoid vaccine for healthy horses, cattle, sheep, goats, and swine. Purified, concentrated with adjuvant for low-dose immunization.
• Tetanus Toxoid - Unconcentrated Tetanus toxoid vaccine with potassium alum adjuvant for horses, cattle, sheep, goats, and swine. Unconcentrated formulation with different dosing.
• Salmonella Dublin-Typhimurium Bacterin Formalin killed, aluminum hydroxide adsorbed vaccine for vaccination of healthy cattle against Salmonella dublin and Salmonella typhimurium infections.
• Caseous D-T Combination vaccine for sheep against tetanus, enterotoxemia (Clostridium perfringens Type D), and caseous lymphadenitis (Corynebacterium pseudotuberculosis). Licensed for sheep only.
• CASE-BAC Corynebacterium pseudotuberculosis bacterin-toxoid for vaccination of healthy sheep against caseous lymphadenitis (CLA).
• Chlamydia Abortus Bacterin Chlamydia psittaci bacterin for vaccination of healthy ewes against Ovine Enzootic Abortion (EAE) with oil adjuvant.

Quantifiable outcome

• Serum antibody products provide 10-21 days of passive immunity protection
• +1 more outcomes

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators3 records

Recent moves5 records

Expansion highlights4 records

Broad incumbents

• Vetoquinol: Independent global animal health company specializing in livestock and companion animal pharmaceuticals and biologicals. Comparable to Colorado Serum in veterinary biologics with similar independent-company positioning but stronger European presence.
• Zoetis: The largest pure-play animal health company globally, Zoetis manufactures a broad portfolio of veterinary vaccines, parasiticides, and diagnostics across livestock and companion animals. It is a broad incumbent competitor to Colorado Serum in the livestock biologics space, though much larger and more diversified.
• Virbac: France-based animal health company offering veterinary vaccines, pharmaceuticals, and diagnostics across companion and production animals. Overlaps with Colorado Serum in livestock biologicals, especially ruminant vaccines, with broader product breadth.
• Merck Animal Health: Division of Merck & Co. offering veterinary vaccines, pharmaceuticals, and health management solutions for livestock and companion animals. Directly competes with Colorado Serum in livestock vaccine categories while operating at far greater scale and geographic reach.
• Boehringer Ingelheim Animal Health: Global animal health business producing veterinary vaccines and biologics for livestock and pets. Competes with Colorado Serum in clostridial, reproductive, and respiratory vaccines for cattle and swine, with substantially broader R&D and international distribution.
• Elanco Animal Health: Animal health company offering vaccines, parasiticides, and therapeutics across livestock and companion animals following its acquisition of Bayer Animal Health. Overlaps with Colorado Serum in livestock biologicals, particularly cattle and swine vaccines.

Direct peers

• Ceva Santé Animale: Global veterinary biologics and pharmaceutical company headquartered in France, with a strong focus on livestock vaccines (poultry, swine, ruminants). Most directly comparable to Colorado Serum in species mix and vaccine-centric portfolio, though with significantly broader geographic reach.
• Phibro Animal Health: Animal health and nutrition company producing vaccines, parasiticides, and nutritional specialties for livestock and poultry. Comparable in size and livestock-vaccine focus to Colorado Serum, though publicly traded and more diversified into feed additives.
• Bimeda Animal Health: Privately held global animal health company manufacturing veterinary pharmaceuticals, vaccines, and nutritional products across livestock species. Closely comparable niche-positioning to Colorado Serum as a privately held livestock biologics specialist with multi-species coverage.

Others

• IDEXX Laboratories: Leading veterinary diagnostics company offering in-clinic lab instruments, reference lab testing, and rapid test kits. Adjacent peer given Colorado Serum's laboratory reagent business (red blood cells, complement, sera) supporting veterinary diagnostic workflows.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/vision-metering-llc

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Colorado Serum Company